Journal of Orthopaedic Research®最新文献

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Preserving Patient-Specific Knee Motion: A Randomized Clinical Trial of Unicompartmental and Total Knee Arthroplasty. 保留患者特有的膝关节运动:单室和全膝关节置换术的随机临床试验。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-10-03 DOI: 10.1002/jor.70077
Gregor Kuntze, Sobhan Panjavi, Evonne Henning, Robert Korley, Gregory Abelseth, Janet Ronsky, Kelly Johnston
{"title":"Preserving Patient-Specific Knee Motion: A Randomized Clinical Trial of Unicompartmental and Total Knee Arthroplasty.","authors":"Gregor Kuntze, Sobhan Panjavi, Evonne Henning, Robert Korley, Gregory Abelseth, Janet Ronsky, Kelly Johnston","doi":"10.1002/jor.70077","DOIUrl":"https://doi.org/10.1002/jor.70077","url":null,"abstract":"<p><p>Unicompartmental knee arthroplasty (UKA) may enable improved functional outcomes compared to total knee arthroplasty (TKA). This randomized controlled trial assessed pre- and postoperative patient reported outcome measures (PROMs) and knee joint gait biomechanics for UKA and TKA patients. Patients were allocated to UKA (Oxford Partial Knee, Biomet, USA) and TKA (Persona CR Knee System, Zimmer, USA) study arms. Patients completed the Oxford Knee Score (OKS) and Western Ontario & McMaster University Arthritis Index (WOMAC), as well as instrumented gait analysis before and 1-year after surgery. Measures of interest: OKS scores; WOMAC sub-scores; Patient-specific correlations and root mean squared errors (RMSE) of stance phase sagittal and coronal knee angles. Statistical analysis included linear mixed-effects models (PROMs; α = 0.0125) and multivariate analysis of variance (gait biomechanics; α = 0.05). A total of 38 patients were recruited (UKA n = 17; TKA n = 21). All PROMs improved significantly following surgery (n = 37, p < 0.001), regardless of surgical technique. A significant effect of surgical technique on gait biomechanics was observed (n = 30, F<sub>4,25</sub>, p = 0.010), where UKA patients displayed greater sagittal plane correlations [median(Q1,Q3) UKA 0.985 (0.967, 0.991), TKA 0.955 (0.942, 0.973)]; p = 0.018] and lower coronal plane RMSEs [UKA 3.6 (2.4,5.0)°, TKA 8.6 (5.1, 11.5)°; p = 0.002]. Although patient-reported outcomes improved similarly following UKA and TKA, UKA more closely preserved native knee kinematics as indicated by the greater similarity of sagittal gait patterns shapes and lower magnitude of coronal angle changes. CLINICAL SIGNIFICANCE: Greater preservation of patient-specific knee kinematics with UKA supports its use in appropriately selected patients and informs the design of targeted, functionally oriented rehabilitation protocols.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrosion in Modular Revision Hip Stem Tapers - A Retrieval Analysis. 模块化修正后的髋关节干锥的腐蚀-检索分析。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-10-02 DOI: 10.1002/jor.70078
Therese Bormann, Haolan Yan, Sebastian Jaeger, Mareike Schonhoff, J Philippe Kretzer
{"title":"Corrosion in Modular Revision Hip Stem Tapers - A Retrieval Analysis.","authors":"Therese Bormann, Haolan Yan, Sebastian Jaeger, Mareike Schonhoff, J Philippe Kretzer","doi":"10.1002/jor.70078","DOIUrl":"https://doi.org/10.1002/jor.70078","url":null,"abstract":"<p><p>In revision hip arthroplasty, modular stems enable intraoperative adjustment of the biomechanics of the hip to ensure a stable joint function even in complex anatomical cases. Modular stem junctions, however, carry the risk of junction degradation due to corrosive processes or even junction breakage. Fretting-corrosion has been mentioned as precursor of junction breakage but has hardly been systematically assessed. To investigate relations between corrosion and fretting, and implant and patient specific parameters and connection strength, respectively, a collection of 53 retrieved modular hip stems of different implant systems was investigated. Corrosion and fretting at the stem-neck taper connection were rated with a modified Goldberg score. Taper contamination was assessed with a similar scoring system. If the hip stems were still joint to the neck piece, the push-out force to detach the parts was recorded as a measure for taper junction strength. A multivariate regression analysis revealed that corrosion and fretting were significantly affected by implantation time, taper contamination, body weight and implant system. Taper junction strength was not altered by corrosion or fretting but by taper contamination. The results indicate that implant geometry parameters are not related to the extent of corrosive degradation at the junction, but taper contamination significantly increased corrosion at taper surfaces. This underlines the importance of the cleanliness of the taper surfaces during hip stem assembly for a long-term stability of the modular implant.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Implant Stability in Cementless Femoral Components With Different Interference Fits. 评估不同过盈配合无骨水泥股骨假体的稳定性。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-10-02 DOI: 10.1002/jor.70079
Esther Sánchez, Christoph Schilling, Thomas M Grupp, Alexander Giurea, Nico Verdonschot, Dennis Janssen
{"title":"Assessing Implant Stability in Cementless Femoral Components With Different Interference Fits.","authors":"Esther Sánchez, Christoph Schilling, Thomas M Grupp, Alexander Giurea, Nico Verdonschot, Dennis Janssen","doi":"10.1002/jor.70079","DOIUrl":"https://doi.org/10.1002/jor.70079","url":null,"abstract":"<p><p>Cementless total knee arthroplasty implants offer advantages over cemented implants, such as bone preservation and easier revision procedures. However, the optimal interference fit required to achieve a good press-fit fixation, essential for both primary and long-term stability, remains uncertain. This study uses finite element analysis to investigate the effects of two interference fits (350 µm and 700 µm) on micromotions, gap behavior, and plastic deformation at the bone-implant interface of a cementless femoral component under various loading conditions. Finite element models were developed using paired cadaveric femurs, incorporating microCT and optical scans. Micromotions were quantified as shear displacement, while gaps were quantified as normal displacement. Bone response was assessed by quantifying the volume of bone experiencing total equivalent plastic strain. The models showed moderate correlation with experimental results, predicting 35% of displacement variability. Although high interference fit implants slightly reduced micromotions and gaps, these differences were not statistically significant (p = 0.252 and p = 0.759, respectively). The high interference fit implants exhibited significantly greater plastic deformation (+15.7%, p = 0.031), particularly at the posterior femoral condyles. These findings suggest that while an increased interference fit does not enhance primary stability, it may lead to more plasticity in the bone, potentially leading to more damage. Thus, optimizing the interference fit is crucial to balance implant fixation and minimize bone damage.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Hounsfield Unit Evaluation of Preoperative CT Scans Predict Surgeon's Preference of Cementless Fixation in Total Knee Arthroplasty? 术前CT扫描的Hounsfield单位评价能否预测全膝关节置换术中外科医生对无骨水泥固定的偏好?
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-30 DOI: 10.1002/jor.70080
Chukwuemeka U Osondu, Hannah Mosher, Jonathan Brutti, Hallie B Remer, Matthew Barra, Juan C Suarez
{"title":"Can Hounsfield Unit Evaluation of Preoperative CT Scans Predict Surgeon's Preference of Cementless Fixation in Total Knee Arthroplasty?","authors":"Chukwuemeka U Osondu, Hannah Mosher, Jonathan Brutti, Hallie B Remer, Matthew Barra, Juan C Suarez","doi":"10.1002/jor.70080","DOIUrl":"https://doi.org/10.1002/jor.70080","url":null,"abstract":"<p><p>Adequate bone quality is necessary for reliable cementless fixation during total knee arthroplasty (TKA). Hounsfield Units (HUs) can be a useful surrogate of bone density, and therefore a proxy of bone quality. We sought to determine whether HU would correlate with subjective intraoperative assessment of bone quality and hence use of cementless fixation. A retrospective review of patients who underwent a robotic-assisted TKA between June 2022 and June 2024 by a single surgeon was conducted. HU measurements were obtained at three regions of interest (ROI) within the tibial plateau on preoperative axial-CT scans. Patients were divided into cementless or cemented tibial implant fixation groups based upon subjective intraoperative bone quality assessment. Demographic data such as age, sex, and BMI were collected. The final cohort included 630 patients. Cementless fixation was used in 58.3% of cases. Cementless patients had a higher combined overall average HU measurement (152.7 vs. 105.6, p < 0.001). Point-biserial correlation showed moderate inverse correlations between implant fixation type and HU measurements (all p < 0.001). ROC analysis and predictive modeling found that the best performance was derived from the combined model followed by combined demographics alone, and then HU measurements alone (AUC: 0.853 vs. 0.808 vs. 0.757). Standalone demographic resulted in the poorer predictive modeling. Ultimately, cementless fixation was associated with higher HU measurements compared to cemented fixation in all 3 ROI. HU in conjunction with combined demographic data offered the greatest confidence in predicting fixation type and therefore may be utilized to aid in decision-making and surgical planning for TKA.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overuse-Induced Muscle Disorder: Establishing a Rat Model to Unravel the Role of Fibro-Adipogenic Progenitor Cells in Intramuscular Fibrosis. 过度使用引起的肌肉疾病:建立大鼠模型揭示纤维脂肪祖细胞在肌内纤维化中的作用。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-30 DOI: 10.1002/jor.70076
Hiroyori Fusagawa, Tatsuya Sato, Azuma Naito, Nao Tokuda, Nao Yamauchi, Akiyoshi Uezumi, Madoka Uezumi, Yuki Saito, Minami Fusagawa, Hiroyuki Takashima, Nobutoshi Ichise, Toshifumi Ogawa, Takuro Karaushi, Noritsugu Tohse, Brian Feeley, Xuhui Liu, Atsushi Teramoto, Takashi Yamada
{"title":"Overuse-Induced Muscle Disorder: Establishing a Rat Model to Unravel the Role of Fibro-Adipogenic Progenitor Cells in Intramuscular Fibrosis.","authors":"Hiroyori Fusagawa, Tatsuya Sato, Azuma Naito, Nao Tokuda, Nao Yamauchi, Akiyoshi Uezumi, Madoka Uezumi, Yuki Saito, Minami Fusagawa, Hiroyuki Takashima, Nobutoshi Ichise, Toshifumi Ogawa, Takuro Karaushi, Noritsugu Tohse, Brian Feeley, Xuhui Liu, Atsushi Teramoto, Takashi Yamada","doi":"10.1002/jor.70076","DOIUrl":"https://doi.org/10.1002/jor.70076","url":null,"abstract":"<p><p>Overuse-induced muscle disorders (OIMD) frequently occur in athletes due to excessive and improper use under high physical demand, often leading to muscle pain and weakness. Limited studies have shown intramuscular fibrosis in OIMD, with fibro-adipogenic progenitors (FAPs), also known as mesenchymal stromal cells (MSCs), playing a crucial role in this fibrosis. This study aimed to develop a rat OIMD model using neuromuscular electrical stimulation-induced isometric exercise (NMES-ISO) and to investigate mechanisms by which excessive exercise without adequate rest leads to OIMD. We hypothesize that daily NMES-ISO would cause muscle weakness and fibrogenesis mediated by FAP activation triggered by muscle fiber damage. Male Wistar rats received daily NMES-ISO loading on the plantar flexor muscles at a lengthened position. Two weeks of NMES-ISO led to decreased muscle torque without muscle mass reduction. Masson-Trichrome stain revealed collagen-rich fibrogenic lesions in the gastrocnemius muscles, while Evans blue stain detected no muscle fiber damage during the first 5 days. MRI showed increased T2*wi signals correlating with fibrogenic areas. Excessive NMES-ISO stimulated FAP proliferation. This study established a rat model of OIMD using NMES-ISO, characterized by muscle weakness and intramuscular fibrogenesis. Contrary to our hypothesis, FAP activation occurred without overt muscle injury, suggesting excessive mechanical loading may directly trigger FAP proliferation and fibrogenesis. It was cautioned that even relatively safe isometric contraction training could lead to FAP activation and intramuscular fibrosis without proper methods and recovery periods.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glenosphere Tilt and Size Predict Shoulder Kinematics During the Hand-to-Back Motion After Reverse Shoulder Arthroplasty. 关节关节倾斜和大小预测肩关节在反向肩关节置换术后手到背运动中的运动学。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-30 DOI: 10.1002/jor.70072
Ajinkya A Rai, Clarissa M LeVasseur, Gillian E Kane, Maria A Munsch, Christopher J Como, Alexandra S Gabrielli, Jonathan D Hughes, William J Anderst, Albert Lin
{"title":"Glenosphere Tilt and Size Predict Shoulder Kinematics During the Hand-to-Back Motion After Reverse Shoulder Arthroplasty.","authors":"Ajinkya A Rai, Clarissa M LeVasseur, Gillian E Kane, Maria A Munsch, Christopher J Como, Alexandra S Gabrielli, Jonathan D Hughes, William J Anderst, Albert Lin","doi":"10.1002/jor.70072","DOIUrl":"https://doi.org/10.1002/jor.70072","url":null,"abstract":"<p><p>Internal rotation (IR) is not reliably improved after reverse shoulder arthroplasty (RSA). This study aimed to identify surgical parameters that predict kinematics of the hand-to-back motion (H2B) after RSA and to identify associations between kinematics and clinical outcomes after RSA. We hypothesized that less humeral retroversion, more lateralization and a larger glenosphere would predict kinematics associated with favorable outcomes post-RSA. Thirty-five patients performed H2B while synchronized biplane radiographs were collected. Digitally reconstructed radiographs, constructed from patient-specific bone plus implant models, were matched to the biplane radiographs to determine kinematics. The total contribution to motion, the end position, peak angles, and range of motion (ROM) were found for all glenohumeral and scapular rotations. The path of the center of the humeral insert on the glenosphere was calculated. Patient-reported outcomes, clinical ROM, and strength were measured. Associations were determined between intraoperative variables and kinematics as well as between kinematics and outcomes. The results demonstrated that glenosphere tilt predicted glenohumeral and scapular kinematics; these kinematics were associated with IR ROM, strength, and more favorable patient-reported outcomes. A larger glenosphere predicted a center of contact that was associated with more strength in IR. All components of scapular rotation were associated with favorable outcomes, suggesting rehabilitation focusing on scapular motion may improve outcomes post-RSA. Glenosphere tilt and size predicted kinematics that were associated with range of motion, strength, and patient-reported outcomes.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probiotic Supplementation Enhances Functional Recovery and Modulates the Serum Metabolome in Mice. 补充益生菌可促进小鼠功能恢复并调节血清代谢组。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-29 DOI: 10.1002/jor.70073
Joseph L Roberts, Parker Kooima, Jarred Kaiser, Jinhua Chi, Haiwei Gu, Hicham Drissi
{"title":"Probiotic Supplementation Enhances Functional Recovery and Modulates the Serum Metabolome in Mice.","authors":"Joseph L Roberts, Parker Kooima, Jarred Kaiser, Jinhua Chi, Haiwei Gu, Hicham Drissi","doi":"10.1002/jor.70073","DOIUrl":"https://doi.org/10.1002/jor.70073","url":null,"abstract":"<p><p>Bone fractures represent common traumatic injuries associated with significant morbidity due to acute and, in some cases, persistent chronic pain. Emerging evidence suggests the gut microbiota plays a critical role in modulating inflammatory and nociceptive signaling; however, its potential as a therapeutic target for alleviating fracture-related pain remains largely unexplored. In this study, we examined the effects of probiotic supplementation with Bifidobacterium longum (B. longum) or Lacticaseibacillus casei (L. casei) on pain-related behaviors, functional recovery, and systemic metabolic changes after unilateral femoral fracture in female C57BL/6J mice. While probiotic supplementation did not significantly alter body composition or whole-body bone mineral density, B. longum supplementation resulted in a modest but significant increase in lumbar spine bone mineral density. Both probiotic strains significantly attenuated pain behaviors compared to vehicle-treated controls, with B. longum demonstrating more rapid and pronounced analgesic effects, including improved hindlimb gait symmetry and reduced compensatory limb usage. Untargeted metabolomic analysis revealed strain-specific and time-dependent changes in systemic metabolic profiles, notably affecting pathways involved in neurotransmitter biosynthesis, tryptophan metabolism, and inflammatory signaling. Collectively, these findings highlight the therapeutic potential of microbiota-targeted strategies as nonpharmacological interventions for improving functional recovery and reducing pain behavior following traumatic bone injury.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Imaging of Articular Cartilage: Current Status and Clinical Applications. 关节软骨的光学成像:现状及临床应用。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-28 DOI: 10.1002/jor.70074
Varun Gopinatth, Alyssa Ashford, Spencer P Lake, Matthew V Smith, Derrick M Knapik
{"title":"Optical Imaging of Articular Cartilage: Current Status and Clinical Applications.","authors":"Varun Gopinatth, Alyssa Ashford, Spencer P Lake, Matthew V Smith, Derrick M Knapik","doi":"10.1002/jor.70074","DOIUrl":"https://doi.org/10.1002/jor.70074","url":null,"abstract":"<p><p>Osteoarthritis (OA) is a condition characterized by cartilage degeneration leading to pain, swelling and disability, while representing a substantial financial burden. Radiographs are most commonly used to evaluate the presence and progression of OA, which can reveal various structural changes within joints. Moreover, standard radiographs, magnetic resonance imaging, and arthroscopy enable visualization of cartilage surfaces and presence of any macroscopic changes. Optical imaging technologies represent nondestructive and noninvasive imaging modalities that allow for evaluation of microscopic changes in articular cartilage, such as fibrillations, clefts, collagen disorganization, and matrix degeneration. OCT and PSOCT can accurately assess cartilage surface disruption and collagen disorganization, with studies performed during arthroscopy further showing its potential to identify early cartilage degeneration. RS can identify disruptions in organization and composition of cartilage based on banding changes in the collagen microstructure. Additional imaging techniques, including photoacoustic imaging, Brillouin spectroscopy, and polarimetry-based techniques can detect articular cartilage degeneration by identifying proteoglycan loss and collagen fibril disorganization. Current clinical applications are limited by small number of human studies and techniques compatible for use during surgery as well as standardized grading systems and imaging processing techniques.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Ultrasound-Guided Tenotomy and Debridement on Pain, Function, and Psychological Factors for Achilles Tendinopathy: A Prospective Cohort Study. 超声引导下的肌腱切开术和清创对跟腱病患者疼痛、功能和心理因素的影响:一项前瞻性队列研究。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-28 DOI: 10.1002/jor.70071
Mederic M Hall, Ruth L Chimenti, Jessica F Danielson, Timothy R Fleagle
{"title":"Effects of Ultrasound-Guided Tenotomy and Debridement on Pain, Function, and Psychological Factors for Achilles Tendinopathy: A Prospective Cohort Study.","authors":"Mederic M Hall, Ruth L Chimenti, Jessica F Danielson, Timothy R Fleagle","doi":"10.1002/jor.70071","DOIUrl":"https://doi.org/10.1002/jor.70071","url":null,"abstract":"<p><p>Ultrasound-guided tenotomy and debridement is a minimally invasive treatment with a low risk of complications for individuals with chronic Achilles tendinopathy. Yet the benefits of this procedure on pain, function, and pain-related psychological factors, as well as predictors of treatment success, remain understudied. A total of 56 individuals with chronic Achilles tendinopathy (mean (SD): age = 55.9 (11) years, BMI = 34.8 (8.2) kg/m<sup>2</sup>, women = 68%) underwent baseline ultrasonography, followed by ultrasound-guided tenotomy and debridement, and rehabilitation. Participants reported pain (0-10), function (Foot and Ankle Ability Measure-ADL), kinesiophobia (Tampa Scale of Kinesiophobia-17), and pain catastrophizing (Pain Catastrophizing Scale) at baseline and for a year following the procedure. Baseline pain was 6.1 (2.2), kinesiophobia was 40.8 (7.1), pain catastrophizing was 13.7 (10.2), and function was 55.9 (17.3). By 6 weeks, there were decreases in pain (mean change (95% CI): -1.9 (-1.1 to -2.6), function: 14.4 (9.3-19.5), kinesiophobia: -5 (-3.2 to -6.9), and pain catastrophizing: -7 (-4.9 to -9.1)). Patient-reported outcomes were similar at 52 weeks (pain: -2.99 (-2.2 to -3.8), function: 25.1 (19.6-30.7), kinesiophobia: -7.5 (-6.1 to -11.4), catastrophizing: -8.5 (-6.1 to -10.8)) following the procedure. Haglund deformity (β: -13.1 (-0.6 to -25.5)) and intratendinous calcifications (β: -14.7 (-1.4 to -28.1)) were associated with smaller improvements in function. No procedure-related complications were reported. Clinical significance: Ultrasound-guided tenotomy and debridement for chronic Achilles tendinopathy may provide positive outcomes for pain, function, and pain-related psychological factors at 6-week and 1-year follow-up. Haglund deformity and tendon calcifications were associated with smaller improvements in function.</p>","PeriodicalId":16650,"journal":{"name":"Journal of Orthopaedic Research®","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in the Movement of the Glenoid Over the Humeral Head Between Subject-Specific and Generalized Glenohumeral Motion. 肱骨头上关节盂运动在个体特异性和广义关节盂运动之间的差异。
IF 2.3 3区 医学
Journal of Orthopaedic Research® Pub Date : 2025-09-28 DOI: 10.1002/jor.70028
Linus Hötzel, Lena Uhlenberg, Heiko Gottschling, Manuel Schroeder, Markus Scheibel, Michael H Amini, Jean-David Werthel, Oliver Amft, Floor M Lambers
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