Journal of Obstetrics and Gynaecology最新文献

筛选
英文 中文
A risk prediction model of gestational diabetes mellitus based on traditional and genetic factors. 基于传统和遗传因素的妊娠糖尿病风险预测模型。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-04 DOI: 10.1080/01443615.2024.2372665
Ying Li, Xinli Zhong, Mengjiao Yang, Lu Yuan, Dandan Wang, Ting Li, Yanying Guo
{"title":"A risk prediction model of gestational diabetes mellitus based on traditional and genetic factors.","authors":"Ying Li, Xinli Zhong, Mengjiao Yang, Lu Yuan, Dandan Wang, Ting Li, Yanying Guo","doi":"10.1080/01443615.2024.2372665","DOIUrl":"https://doi.org/10.1080/01443615.2024.2372665","url":null,"abstract":"<p><strong>Background: </strong>Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication during pregnancy. We aimed to evaluate a risk prediction model of GDM based on traditional and genetic factors.</p><p><strong>Methods: </strong>A total of 2744 eligible pregnant women were included. Face-to-face questionnaire surveys were conducted to gather general data. Serum test results were collected from the laboratory information system. Independent risk factors for GDM were identified using univariate and multivariate logistic regression analyses. A GDM risk prediction model was constructed and evaluated with the Hosmer-Lemeshow goodness-of-fit test, goodness-of-fit calibration plot, receiver operating characteristic curve and area under the curve.</p><p><strong>Results: </strong>Among traditional factors, age ≥30 years, family history, GDM history, impaired glucose tolerance history, systolic blood pressure ≥116.22 mmHg, diastolic blood pressure ≥74.52 mmHg, fasting plasma glucose ≥5.0 mmol/L, 1-hour postprandial blood glucose ≥8.8 mmol/L, 2-h postprandial blood glucose ≥7.9 mmol/L, total cholesterol ≥4.50 mmol/L, low-density lipoprotein ≥2.09 mmol/L and insulin ≥11.5 mIU/L were independent risk factors for GDM. Among genetic factors, 11 single nucleotide polymorphisms (SNPs) (rs2779116, rs5215, rs11605924, rs7072268, rs7172432, rs10811661, rs2191349, rs10830963, rs174550, rs13266634 and rs11071657) were identified as potential predictors of the risk of postpartum DM among women with GDM history, collectively accounting for 3.6% of the genetic risk.</p><p><strong>Conclusions: </strong>Both genetic and traditional factors contribute to the risk of GDM in women, operating through diverse mechanisms. Strengthening the risk prediction of SNPs for postpartum DM among women with GDM history is crucial for maternal and child health protection.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2372665"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing nomograms for predicting disease-free survival and overall survival in patients with breast cancer. 建立预测乳腺癌患者无病生存期和总生存期的提名图。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-15 DOI: 10.1080/01443615.2024.2361435
Ling Zhou, Lifen Bai, Huiyin Zhu, Chongyong Guo, Sheng Liu, Lu Yin, Jian Sun
{"title":"Establishing nomograms for predicting disease-free survival and overall survival in patients with breast cancer.","authors":"Ling Zhou, Lifen Bai, Huiyin Zhu, Chongyong Guo, Sheng Liu, Lu Yin, Jian Sun","doi":"10.1080/01443615.2024.2361435","DOIUrl":"https://doi.org/10.1080/01443615.2024.2361435","url":null,"abstract":"<p><strong>Background: </strong>Prognostic factors-based nomograms have been utilised to detect the likelihood of the specific cancer events. We have focused on the roles of aldehyde dehydrogenase 1 (ALDH1) and p-AKT in predicting the prognosis of BC patients. This study was designed to establish nomograms based on the integration of aldehyde dehydrogenase 1 (ALDH1) and p-AKT in predicting the disease-free survival (DFS) and overall survival (OS) of breast cancer (BC) patients.</p><p><strong>Methods: </strong>Demographic and clinical data were obtained from BC patients admitted to our hospital between September 2015 and August 2016. Univariate and multivariate Cox regression analyses were utilised to analyse the risk factors of recurrence and mortality. The nomograms for predicting the DFS and OS were established using the screened risk factors. Stratified analysis was performed with the cut-off value of exp (pi) of 4.0-fold in DFS and OS, respectively.</p><p><strong>Results: </strong>Multivariate Cox regression analysis indicated that ALDH, p-AKT and pathological stage III were independent risk factors for the recurrence among BC patients. ALDH1, p-AKT, pathological stage III and ER<sup>-</sup>/PR<sup>-</sup>/HER2<sup>-</sup> were independent risk factors for the mortality among BC patients. The established nomograms based on these factors were effective for predicting the DFS and OS with good agreement to the calibration curve and acceptable area under the receiver operating characteristic (ROC) curve. Finally, stratified analyses showed patients with a low pi showed significant decrease in the DFS and OS compared with those of high risk.</p><p><strong>Conclusion: </strong>We established nomograms for predicting the DFS and OS of BC patients based on ALDH1, p-AKT and pathological stages. The ER<sup>-</sup>/PR<sup>-</sup>/HER2<sup>-</sup> may be utilised to predict the OS rather than DFS in the BC patients.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2361435"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why is ethnicity a risk factor for postpartum haemorrhage? 为什么种族是产后出血的风险因素?
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-17 DOI: 10.1080/01443615.2024.2380084
Hashviniya Sekar, Karen Joash
{"title":"Why is ethnicity a risk factor for postpartum haemorrhage?","authors":"Hashviniya Sekar, Karen Joash","doi":"10.1080/01443615.2024.2380084","DOIUrl":"10.1080/01443615.2024.2380084","url":null,"abstract":"<p><p>Postpartum haemorrhage (PPH) is a leading cause of maternal mortality and morbidity on a global scale. Ethnic background is known to be a determinant of variation in the outcomes of women receiving maternity care across the world. Despite free maternity healthcare in the UK National Health Service, women with an ethnic minority background giving birth have an increased risk of PPH, even when other characteristics of the mother, the baby and the care received are considered. Improving PPH care has significant implications for improving health equity. The underlying causes of ethnic disparities are complex and multifaceted. It requires a deep dive into analysing the unique patient factors that make these women more likely to suffer from a PPH as well as reflecting on the efficacy of intra and postpartum care and prophylactic treatment these women receive.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2380084"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NK-92 cells activated by IL-2 inhibit the progression of endometriosis in vitro. 由 IL-2 激活的 NK-92 细胞可抑制子宫内膜异位症在体外的发展。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-21 DOI: 10.1080/01443615.2024.2372682
Jun Yao, Li-Jiao Zhang, Zhe Zhou, Mao-Fang Hua
{"title":"NK-92 cells activated by IL-2 inhibit the progression of endometriosis in vitro.","authors":"Jun Yao, Li-Jiao Zhang, Zhe Zhou, Mao-Fang Hua","doi":"10.1080/01443615.2024.2372682","DOIUrl":"10.1080/01443615.2024.2372682","url":null,"abstract":"<p><strong>Background: </strong>Interleukin (IL)-2 is a key cytokine capable of modulating the immune response by activating natural killer (NK) cells. This study was recruited to explore the therapeutic potential of IL-2-activated NK-92 cells in endometriosis in vitro.</p><p><strong>Methods: </strong>Ectopic endometrial stromal cells (EESCs) were isolated and co-cultured with IL-2-activated NK-92 cells at varying effector-to-target (E:T) ratios (1:0 [Control], 1:1, 1:3, and 1:9). The viability, cytotoxicity, and cell surface antigen expression of IL-2-activated NK-92 cells were assessed. The viability, apoptosis, invasion, and migration ability of EESCs co-cultured with NK-92 cells at different ratios were evaluated. The apoptosis-related proteins, invasion and migration-related proteins as well as MEK/ERK pathway were examined via western blot. Each experiment was repeated three times.</p><p><strong>Results: </strong>IL-2 activation enhanced NK-92 cytotoxicity in a concentration-dependent manner. Co-culturing EESCs with IL-2-activated NK-92 cells at E:T ratios of 1:1, 1:3, and 1:9 reduced EESC viability by 20%, 45%, and 70%, respectively, compared to the control group. Apoptosis rates in EESCs increased in correlation with the NK-92 cell proportion, with the highest rate observed at a 1:9 ratio. Moreover, EESC invasion and migration were significantly inhibited by IL-2-activated NK-92 cells, with a 60% reduction in invasion and a 50% decrease in migration at the 1:9 ratio. Besides, the MEK/ERK signalling pathway was down-regulated in EESCs by IL-2-activated NK-92 cells.</p><p><strong>Conclusion: </strong>IL-2-activated NK-92 cells exhibit potent cytotoxic effects against EESCs. They promote EESC apoptosis and inhibit viability, invasion, and migration through modulating the MEK/ERK signalling pathway.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2372682"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statement of Retraction: Impact of maternal iron deficiency anaemia on the expression of the newly discovered multi-copper ferroxidase, Zyklopen, in term placentas. 撤回声明:母体缺铁性贫血对新发现的多铜铁氧化酶 Zyklopen 在足月胎盘中表达的影响。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI: 10.1080/01443615.2024.2382547
{"title":"Statement of Retraction: Impact of maternal iron deficiency anaemia on the expression of the newly discovered multi-copper ferroxidase, Zyklopen, in term placentas.","authors":"","doi":"10.1080/01443615.2024.2382547","DOIUrl":"https://doi.org/10.1080/01443615.2024.2382547","url":null,"abstract":"","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2382547"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Red flags for randomisation. 随机化的红旗。
IF 1.3 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-03-04 DOI: 10.1080/01443615.2024.2303830
Natasha Weaver
{"title":"Red flags for randomisation.","authors":"Natasha Weaver","doi":"10.1080/01443615.2024.2303830","DOIUrl":"10.1080/01443615.2024.2303830","url":null,"abstract":"","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2303830"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? 子宫内膜癌术前血液学参数异常;反映肿瘤侵袭性还是放疗反应减弱?
IF 1.3 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-01-07 DOI: 10.1080/01443615.2023.2294332
Stephanie W Vrede, Hannah Donkers, Casper Reijnen, Anke Smits, Nicole C M Visser, Peggy M Geomini, Huy Ngo, Dennis van Hamont, Brenda M Pijlman, Maria Caroline Vos, Marc P L M Snijders, Roy Kruitwagen, Ruud L M Bekkers, Khadra Galaal, Johanna M A Pijnenborg
{"title":"Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?","authors":"Stephanie W Vrede, Hannah Donkers, Casper Reijnen, Anke Smits, Nicole C M Visser, Peggy M Geomini, Huy Ngo, Dennis van Hamont, Brenda M Pijlman, Maria Caroline Vos, Marc P L M Snijders, Roy Kruitwagen, Ruud L M Bekkers, Khadra Galaal, Johanna M A Pijnenborg","doi":"10.1080/01443615.2023.2294332","DOIUrl":"10.1080/01443615.2023.2294332","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour aggressiveness, or also impact response to adjuvant treatment. Therefore, our primary aim is to evaluate the prognostic relevance of anaemia, thrombocytosis and leucocytosis on survival in EC. Secondary, to explore their predictive relevance in response to radiotherapy in EC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective multicentre cohort study was performed within 10 hospitals. Preoperative haematological parameters were defined as: Anaemia - haemoglobin &lt;7.45 mmol/L (&lt;12 g/Dl), thrombocytosis - platelets &gt;400 × 10&lt;sup&gt;9&lt;/sup&gt; platelets/L, leucocytosis - leukocytes &gt;10 × 10&lt;sup&gt;9&lt;/sup&gt;/L. The relationship of haematological parameters with clinicopathological characteristics, ESGO/ESTRO/ESP risk groups and survival were evaluated. Furthermore, the predictive value of haematological parameters was determined on the overall response to adjuvant radiotherapy and for the ESGO/ESTRO/ESP intermediate-risk group solely receiving radiotherapy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 894 patients were included with a median follow-up of 4.5 years. Anaemia was present in 103 (11.5%), thrombocytosis in 79 (8.8%) and leucocytosis in 114 (12.7%) patients. The presence of anaemia or thrombocytosis was significantly associated with ESGO/ESTRO/ESP high-risk (respectively, &lt;i&gt;P&lt;/i&gt; = 0.002 and &lt;i&gt;P&lt;/i&gt; = 0.041). In the entire cohort, anaemia remained independently associated with decreased disease-specific survival (HR 2.31, 95% CI (1.19-4.50), &lt;i&gt;P&lt;/i&gt; = 0.013) after adjusting for age, the abnormal haematological parameters and ESGO/ESTRO/ESP risk groups. In patients that were treated with adjuvant radiotherapy (&lt;i&gt;n&lt;/i&gt; = 239), anaemia was associated with significant reduced 5-year disease-specific and recurrence-free survival (&lt;i&gt;P&lt;/i&gt; = 0.005 and &lt;i&gt;P&lt;/i&gt; = 0.025, respectively). In ESGO/ESTRO/ESP intermediate risk patients that received solely vaginal brachytherapy (&lt;i&gt;n&lt;/i&gt; = 74), anaemia was associated with reduced disease-specific survival (&lt;i&gt;P&lt;/i&gt; = 0.041).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Current data demonstrate the importance of preoperative anaemia as independent prognostic factor in patients with EC. Moreover, anaemia seems to be associated with reduced response to radiotherapy. Prospective validation in a larger study cohort is needed to verify anaemia as predictive biomarker for radiotherapy.&lt;b&gt;&lt;i&gt;What is already known on this subject?&lt;/i&gt;&lt;/b&gt; In endometrial cancer, preoperative abnormal haematological parameters like, anaemia, thrombocytosis and leucocytosis appears to be associated with FIGO advanced-stage and unfavourable outcome.&lt;b&gt;&lt;i&gt;What do the results of this study add?&lt;/i&gt;&lt;/b&gt; It remains unclear whether anaemia, thrombocytosis or leucocytosis solely reflecting worse prognosis by advanced tumour stage, or also","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2294332"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal and foetal risks associated with teenage pregnancy - a comparative retrospective study in Turkey. 与少女怀孕有关的母体和胎儿风险--土耳其的一项比较性回顾研究。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-06-18 DOI: 10.1080/01443615.2024.2364787
Mehmet Nuri Duran, Eren Pek, Süreyya Sarıdaş Demir, Kübra Özkan Karacaer, Bülent Demir
{"title":"Maternal and foetal risks associated with teenage pregnancy - a comparative retrospective study in Turkey.","authors":"Mehmet Nuri Duran, Eren Pek, Süreyya Sarıdaş Demir, Kübra Özkan Karacaer, Bülent Demir","doi":"10.1080/01443615.2024.2364787","DOIUrl":"https://doi.org/10.1080/01443615.2024.2364787","url":null,"abstract":"<p><strong>Background: </strong>Adolescent pregnancy is defined as pregnancy occurring in young women between the ages of 10 and 19 years. Adolescent pregnancies, which are among the social healthcare concerns in developed and developing countries, have negative effects on maternal and infant health. Pregnancy in adolescence puts the health of both the mother and child at risk, as adolescent pregnancies have higher rates of eclampsia, systemic infection, low birth weight, and preterm delivery compared to other pregnancies. In this study, the effects of education level, smoking, and marital status on maternal and foetal outcomes in adolescent pregnancies were evaluated.</p><p><strong>Methods: </strong>The records of a total of 960 pregnant women (480 pregnant adolescents aged 15-19 years and 480 pregnant adult women aged 20-26 years) were examined retrospectively. The demographic data of the groups and maternal and foetal outcomes of the pregnancies were compared. A logistic regression model was established as a statistical method for reducing confounding effects.</p><p><strong>Results: </strong>Unmarried women were statistically significantly more prevalent in the adolescent group (38.3% vs. 7.3%). Among the considered risk factors, preeclampsia (2.9% vs. 0.8%) and smoking (29.8% vs. 9.8%) were statistically significantly more common in the adolescent group. When the groups were compared in terms of risk factors in pregnancy, it was found that pregnancy in adolescence was associated with a 3.04-fold higher risk of smoking, 5.25-fold higher risk of being unmarried, 3.50-fold higher risk of preeclampsia, and 1.70-fold higher risk of intrauterine growth retardation (IUGR).</p><p><strong>Conclusions: </strong>This study demonstrates an increased risk of preeclampsia, IUGR, and smoking during pregnancy in adolescent pregnant women. These findings can be used to identify adolescent pregnancies requiring specific assistance and to take measures to reduce the probability of adverse outcomes.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2364787"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pregnancy outcomes of foetal reduction from twin to singleton gestation compared to ongoing twin gestations: a systematic review and meta-analysis. 从双胎妊娠减胎至单胎妊娠与持续双胎妊娠的妊娠结局比较:系统综述和荟萃分析。
IF 0.9 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-07-08 DOI: 10.1080/01443615.2024.2371955
Bijun Mao, Li Chen
{"title":"Pregnancy outcomes of foetal reduction from twin to singleton gestation compared to ongoing twin gestations: a systematic review and meta-analysis.","authors":"Bijun Mao, Li Chen","doi":"10.1080/01443615.2024.2371955","DOIUrl":"10.1080/01443615.2024.2371955","url":null,"abstract":"<p><strong>Background: </strong>Foetal reduction, which involves selectively terminating one or more foetuses in a multiple gestation pregnancy, has become more common. This systematic review and meta-analysis aims to assess and compare pregnancy outcomes of foetal reduction from twin to singleton gestation to ongoing twin gestations.</p><p><strong>Methods: </strong>A comprehensive search of electronic databases (MEDLINE, EMbase, Cochrane Library, CINAHL and PsycINFO) was done for studies published until 15 April 2023. The outcomes analysed included gestational diabetes mellitus (DM), hypertension, caesarean delivery, foetal loss, perinatal death, preterm birth (PTB), intrauterine growth restriction (IUGR), preterm prelabour rupture of membranes (PPROM) and birth weight.</p><p><strong>Results: </strong>A total of 13 studies comprising 1241 cases of twin to singleton foetal reduction gestation were compared to 20,693 ongoing twin gestations. Our findings indicate that foetal reduction was associated with a significantly lower risk of developing maternal gestational DM (odds ratio [OR] = 0.40, 95% confidence interval [CI] 0.27-0.59) and hypertension (OR = 0.36, 95% CI 0.23-0.57) compared to the control group. Incidence rate of caesarean delivery (OR = 0.65, 95% CI 0.53-0.81) after foetal reduction was significantly lower compared to ongoing twin gestations. There was a 63% lower chance of PTB before 37 weeks of pregnancy. However, there was no significant association between foetal reduction and outcomes such as foetal loss, perinatal death, IUGR and PPROM.</p><p><strong>Conclusions: </strong>Our findings suggest that foetal twin to singleton reduction entails potential benefits as compared to ongoing twin gestations. Further well planned studies are needed to explore underlying mechanisms to understanding of the outcomes associated with foetal reduction procedures and inform clinical decision-making for pregnant individuals and healthcare providers alike.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2371955"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors that influence the choice of long-acting reversible contraceptive use among adolescents post-abortion in Chongqing, China: a cross-sectional study. 影响中国重庆流产后青少年选择使用长效可逆避孕药的因素:一项横断面研究。
IF 1.3 4区 医学
Journal of Obstetrics and Gynaecology Pub Date : 2024-12-01 Epub Date: 2024-02-14 DOI: 10.1080/01443615.2024.2316625
Fengzhen Jin, Yuanpei Yang, Junjie Sun, Ruiyue Li, Fei Yao, Xiaoli Liu
{"title":"Factors that influence the choice of long-acting reversible contraceptive use among adolescents post-abortion in Chongqing, China: a cross-sectional study.","authors":"Fengzhen Jin, Yuanpei Yang, Junjie Sun, Ruiyue Li, Fei Yao, Xiaoli Liu","doi":"10.1080/01443615.2024.2316625","DOIUrl":"10.1080/01443615.2024.2316625","url":null,"abstract":"<p><strong>Background: </strong>Induced abortion can seriously harm the physical and mental health of adolescent women. Long-acting reversible contraception (LARC) can effectively reduce unplanned pregnancies and prevent repeated abortions among adolescents. This study aimed to analyse the factors affecting the choice of LARC among adolescents in Chongqing of China.</p><p><strong>Methods: </strong>A total of 555 adolescents who underwent induced abortions for unplanned pregnancies between January 2019 and October 2021 were selected as study subjects. Logistic regression analysis was used to determine the factors affecting adolescent LARC choices following induced abortions.</p><p><strong>Results: </strong>The factors that affected adolescent LARC choices included an average monthly income ≥ ¥3000 (OR = 3.432, 95% CI: 1.429∼8.244), history of previous abortions (OR = 3.141, 95% CI: 1.632∼6.045), worrying about unplanned pregnancy (OR = 0.365, 95% CI: 0.180∼0.740), parental support for using LARC (OR = 3.549, 95% CI: 1.607∼7.839), sexual partners' support for using LARC (OR = 2.349, 95% CI: 1.068∼5.167), concerns about using LARC (OR = 0.362, 95% CI: 0.176∼0.745), and willingness to use free IUDs (OR = 13.582, 95% CI: 7.173∼25.717).</p><p><strong>Conclusion: </strong>Cost is one of the factors affecting LARC choices. Parents and sexual partners may play important role in the choice of LARC.</p>","PeriodicalId":16627,"journal":{"name":"Journal of Obstetrics and Gynaecology","volume":"44 1","pages":"2316625"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139729856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信