{"title":"Progress of Researches on Pharmacological Effects and Bioavailability of Tangeretin.","authors":"Wanqing Wang, Tianqi Jia, Yifan Zhang, Yawen Zhou","doi":"10.5650/jos.ess24169","DOIUrl":"https://doi.org/10.5650/jos.ess24169","url":null,"abstract":"<p><p>Tangeretin is one of the most abundant polymethoxyflavones in citrus peel and its pharmacological effects are extremely rich. However, due to its poor solubility, bitter taste and poor oral bioavailability, the oral administration of tangeretin is still limited, which seriously limits its application in industrial production. The establishment of encapsulation and delivery systems to improve bioavailability is an effective method. This paper reviewed the research progress of the structure and properties, pharmacological effects and main methods to improve bioavailability of tangeretin, including emulsion delivery, lipid encapsulation, microencapsulation and other delivery and utilization research and application. The article aims to provide theoretical basis for the high-value application of tangeretin in functional food and pharmaceutical industry.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 1","pages":"13-23"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antioxidation Performance of Essential Oils of Herbs and Spices in White Mineral Oils.","authors":"Imren Meydan, Basar Uyar","doi":"10.5650/jos.ess24218","DOIUrl":"https://doi.org/10.5650/jos.ess24218","url":null,"abstract":"<p><p>White mineral oil (paraffin oil) is a colorless, tasteless and hydrophobic oil used in many different industries. The oil is prone to oxidation, which negatively affects its properties and performance. In this study, six different essential oils obtained from herbs and spices (Sage, Laurel, Basil, Rosemary, Thyme, Oregano) were added to pharmaceutical and technical grade white mineral oils at 0.1 - 0.8 % (w/w) concentrations. Light, heat and air were applied to induce and accelerate oxidation. The total acid number, viscosity, and DPPH radical scavenging activity of the oils were measured in addition to the TGA and DSC tests to evaluate the anti-oxidation performance of the additives. The results showed that combined heat and oxygen treatment was the most effective of the three conditions tested to cause oxidation. The highest DPPH scavenging activities were obtained with oregano and thyme essential oils (up to 59% and 54% DPPH increase, respectively) and DPPH% activity increased linearly with increasing essential oil concentration. Thermal analyses, total acid number and viscosity change data also suggested the essential oils of Thyme, Oregano and Laurel as the best antioxidant additives to be used in white oils.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 7","pages":"633-645"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation and Characterization of Emulsifier-free, Submicron-sized Monodisperse Rice Bran Wax Particles and their Applicability.","authors":"Shigesaburo Ogawa, Maya Ono, Shogo Sugano, Teruyuki Nakano, Koichi Niwa","doi":"10.5650/jos.ess25066","DOIUrl":"https://doi.org/10.5650/jos.ess25066","url":null,"abstract":"<p><p>The development of an optimal material design is crucial for rice bran wax (RBW) to achieve significant advancements in value-added byproducts. In this study, emulsifier-free, submicron-sized, monodisperse RBW particles were prepared via melt emulsification using a combination of a high-HLB emulsifier-decaglycerin stearate or Tween 20-and a low-HLB emulsifier-glyceryl stearate or Span 20. High dispersibility was achieved due to the zeta-potential generated by the surrounding surfactants, resulting in monodispersed submicron-sized RBW particles. Surface cleaning with ethanol effectively removed surface-adsorbed emulsifiers, yielding emulsion-free RBW particles. Due to the hydrophobic nature of the wax particles, high solvent repellencies were observed, along with the formation of colloidal assemblies such as liquid marbles and W/O Pickering emulsions using cosmetics-applicable liquids. Based on X-ray diffraction analysis and differential scanning calorimetry, RBW was identified as a promising candidate for emulsifier-free submicron-sized particles due to its high crystallinity, which facilitates the effective elimination of emulsifiers.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 7","pages":"567-576"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aroma Compounds of Fresh Leaves and their Dried Powders in Angelica acutiloba Kitagawa.","authors":"Shiro Ezoe, Katsumi Nakano, Yoshihiko Akakabe","doi":"10.5650/jos.ess25099","DOIUrl":"https://doi.org/10.5650/jos.ess25099","url":null,"abstract":"<p><p>This study aimed to investigate the aroma compounds in fresh leaves and their dried powders in Angelica acutiloba Kitagawa (yamato-tōki). Essential oils were extracted from the dried powders of leaves in A. acutiloba Kitagawa using a simultaneous distillation extraction (SDE) technique and analyzed using GC/MS. The phthalides in the essential oils were accounted for 41.46%, followed by sesquiterpene hydrocarbonds (19.45%) and monoterpene hydrocarbonds (18.74%). A major component in the oils, detected at 34.95%, was isolated using silica gel column chromatography and determined as (Z)-ligustilide using 1D and 2D NMR spectroscopy. We also purified (Z)-butylidenephthalide as the minor phthalide. In the oils extracted from fresh leaves using SDE, the monoterpene hydrocarbonds were accounted for 52.69%, followed by phthalides (20.95%) and sesquiterpene hydrocarbonds (10.63%). The most dominant aroma compound identified was γ-terpinene, followed by (Z)-ligustilide, p-cymene and β-caryophyllene using GC/MS. Both oils exhibited a celery-like aroma. It could be revealed that investigations on the composition of related phthalides in Angelica varieties are necessary to clarify their therapeutic effects and mechanisms.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 9","pages":"837-843"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weijie Shang, Yanjie Huang, Yihang Zhang, Ruojia Li, Liping Dai
{"title":"Quantification of Fatty Acids from Arctium lappa L. Leaves by <sup>13</sup>C qNMR and HPLC-CAD.","authors":"Weijie Shang, Yanjie Huang, Yihang Zhang, Ruojia Li, Liping Dai","doi":"10.5650/jos.ess25041","DOIUrl":"https://doi.org/10.5650/jos.ess25041","url":null,"abstract":"<p><p>Arctium lappa L. (burdock) leaves is effective in the traditional treatment of stroke. Fatty acids are abundant in burdock leaves, and may play an important role in the treatment of stroke. A new procedure was presented that provides <sup>13</sup>C NMR-based quantitative measurements of total content, average chain length, average degree of unsaturation, and average polyunsaturation of fatty acids in burdock leaves from five producing areas. The content of five fatty acids in burdock leaves, including α-linolenic acid, linoleic acid, palmitic acid, oleic acid, and stearic acid, were further determined by HPLC-CAD. Among five producing areas, the results of <sup>13</sup>C qNMR showed that the content of total fatty acids in burdock leaves ranged from 8.62 to 24.51 μmol·g<sup>-1</sup>, the average chain length ranged from 19.67 to 23.14, the average degree of unsaturation ranged from 1.19 to 3.91, and the average polyunsaturated moieties ranged from 0.23 to 2.37. The results of HPLC-CAD showed that the contents of α-linolenic acid, linoleic acid, palmitic acid, oleic acid and stearic acid were 0.66 - 6.60 mg·g<sup>-1</sup>, 0.38-4.41 mg·g<sup>-1</sup>, 0.46-3.55 mg·g<sup>-1</sup>, 0.18-0.20 mg·g<sup>-1</sup> and 0.10-0.32 mg·g<sup>-1</sup> respectively. The developed <sup>13</sup>C qNMR method can accurately determine the total fatty acids content and provide relevant information on the fatty acids structure types in burdock leaves. This method is capable of complementing existing fatty acids quantitative methodologies, circumventing their deficiencies, and its application can be extended to other plants.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 9","pages":"825-835"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation and Characterization of Luminescent Alkyl β-D-galactoside-curcuminoid Dye Composites via Micelle-to-fiber Transition in Aqueous Systems.","authors":"Shigesaburo Ogawa, Kotaro Ekida, Akane Ueno, Nanako Nomura, Kumiko Yamamoto, Koichi Niwa","doi":"10.5650/jos.ess25067","DOIUrl":"https://doi.org/10.5650/jos.ess25067","url":null,"abstract":"<p><p>The precise understanding and control of the phase behavior of surfactant aqueous systems have enabled the development of diverse materials in the fields of foods, cosmetics, and pharmaceuticals. In this study, we investigated aqueous systems of the bio-based surfactants alkyl β-d-galactosides (CnGals, where n represents the chain length; n = 6, 8, 10, 11, and 12). First, we confirmed that CnGals aqueous systems formed micelle solutions upon heating and hydrogel upon cooling. In particular, decyl β-d-galactoside (C10Gal) exhibited a homogeneous fiber morphology at low concentrations (0.1 wt.%), whereas larger n values afforded an inhomogeneous solid matrix and smaller n values required higher concentrations or did not form a fiber structure. In addition, the C10Gal micelles solubilized curcuminoid dyes such as demethoxycurcumin and curcumin and allowed preparing luminescent fibers upon cooling the solution. The removal of water afforded the corresponding C10Gal-dye solid composite with a high luminescence quantum yield. Powder X-ray diffraction and differential thermal analysis suggested the formation of a stable adduct or cocrystal with a unique interaction between the curcuminoid dyes and C10Gal. Therefore, we successfully prepared an environmentally friendly, highly luminescent organic solid via micelle-to-fiber transition of an environmentally friendly surfactant induced by a mild temperature change.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 8","pages":"689-699"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Satoshi Horikoshi, Takeru Matsumoto, Megumi Nakamura, Nick Serpone
{"title":"Microwave-Induced In-Liquid Plasma for Chemical and Environmental Applications: Investigation of Wastewater Treatment Contaminated by Microplastics and Toxic Metal Ions.","authors":"Satoshi Horikoshi, Takeru Matsumoto, Megumi Nakamura, Nick Serpone","doi":"10.5650/jos.ess25141","DOIUrl":"https://doi.org/10.5650/jos.ess25141","url":null,"abstract":"<p><p>This study utilized a microwave-induced in-liquid plasma (MILP) device to treat water contaminated with microplastics (MPs) and metal ions. The performance of the device was initially assessed using a rhodamine-B (RhB) aqueous dye solution in a circulation-type reactor, yielding a greater degradation efficiency compared to conventional batch treatments. Polyethylene (PE) particles (diameter, 20 μm; average molecular weight, 1.8 million) served as a model for MPs to evaluate their disposal and degradation under continuous circulation treatment. A plasma-induced polymer gel synthesis method was employed to remove metal ions, achieving over 80% removal of copper, tin, lead, and mercury within 5 minutes. These findings highlight the significant potential of MILP technology for innovative advanced water treatment applications.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 10","pages":"949-959"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adsorption and Lubrication of Mixtures Consisting of Cationic Surfactant and Long-Chain Alcohol in Aqueous Media.","authors":"Kenichi Sakai, Hinano Tomari, Haruhiko Tsunoda, Kyosuke Arakawa, Koji Tsuchiya, Masaaki Akamatsu, Hideki Sakai","doi":"10.5650/jos.ess25143","DOIUrl":"https://doi.org/10.5650/jos.ess25143","url":null,"abstract":"<p><p>We studied the adsorption and lubrication of cationic surfactants on silica in the presence of 1-hexadecanol (C16OH). The surfactants employed in this study were quaternary ammonium salts with different alkyl chain lengths (alkyltrimethylammonium chloride, CnTAC, where n is the alkyl chain length of 14, 16, and 18). The mixing of CnTAC, C16OH, and water generally yields the structure of \"α-form hydrated crystals\" or the structural unit of \"lamellar gel networks\" at appropriate compositions. In these structures, the alkyl chains of CnTAC and C16OH are packed in the hexagonal arrangement within lamellar bilayers. Quartz crystal microbalance with dissipation monitoring technique suggested that the adsorbed vesicular aggregates of CnTAC and C16OH flattened on the silica surface. The larger vesicular aggregates formed a viscosity-dominant thicker adsorption film in the initial stage, and then experienced the flattening more significantly to yield an elasticity-dominant thin film. At a given size of the vesicular aggregates, the alkyl chain length of CnTAC did not make large impact on the adsorption in their steady state. The adsorption film achieved excellent lubricity, being irrespective on the size of the vesicular aggregates and the alkyl chain length of CnTAC. We anticipate that these findings will be useful in formulating \"α-gels\" in various personal care applications.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 11","pages":"983-990"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145437314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shadab Md, Ibrahim M Ibrahim, Mohammed W Al-Rabia, Mohammad Kashif Iqubal, Musarrat Husain Warsi
{"title":"Development of Turmeric Oil-based 5-Fluorouracil Loaded Lipid Nanogel for Improved Dermatokinetic and Drug Deposition for Skin Cancer.","authors":"Shadab Md, Ibrahim M Ibrahim, Mohammed W Al-Rabia, Mohammad Kashif Iqubal, Musarrat Husain Warsi","doi":"10.5650/jos.ess25076","DOIUrl":"https://doi.org/10.5650/jos.ess25076","url":null,"abstract":"<p><p>Hydrophilicity and side effects are the major problems in the effective and safe use of 5-fluorouracil (5FL) for skin cancer. Lipid-based nanocarriers, especially nanostructured lipid carriers (NLC), show specific advantages of high drug loading and low drug leakage for successful delivery of 5FL. Therefore, a lipid-nanogel system of 5FL-loaded NLC (5FL-LNG) for topical delivery was aimed at in the present study. For NLC development, a mixture of turmeric oil and labrasol (70:30) was determined as oil, and then solid lipid (tefose 1500) and surfactant (Tween 80) were selected. Central composite design was used for formulation optimization. Design suggested a formulation prepared with 1.5% binary mixture, 6% surfactant, and 8 min of sonication time for the optimized 5FL-NLC. Optimized 5FL-NLC had particle size, zeta potential, entrapment efficiency, and transmittance values of 223.47±2.42 nm, -14.90±0.95 mV, 78.81±1.63%, and 94.79±0.58%, respectively. The DSC revealed homogeneous and amorphous nature of 5FL-NLC. 5FL-LNG formulation was prepared with 1% w/w Carbopol<sup>®</sup> 934 and compared with conventional Carbopol<sup>®</sup> 934 gel of 5FL. Spreadability and extrudability were better for 5FL-LNG and were further confirmed by texture analysis. In vitro release and skin permeation (both in vitro and ex vivo) of 5FL was better for 5FL-LNG compared to the conventional gel. Dermatokinetic data showed that C<sub>skin-max</sub> and AUC<sub>0-8h</sub> values were significantly higher for 5FL-LNG. Confocal laser scanning microscopy confirmed noticeable betterment of 5FL delivery to skin epidermis and dermis from 5FL-LNG compared to conventional gel. Overall, developed 5FL-LNG formulation demonstrated its significant results for effective topical application and, therefore, could be subjected to further pre-clinical and clinical studies.</p>","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 12","pages":"1091-1106"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Errata for J. Oleo Science, Vol.74, No.9 p.820 (2025).","authors":"","doi":"10.5650/jos.ess25111e","DOIUrl":"https://doi.org/10.5650/jos.ess25111e","url":null,"abstract":"","PeriodicalId":16626,"journal":{"name":"Journal of oleo science","volume":"74 12","pages":"1145"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}