Journal of Neuropsychiatry and Clinical Neurosciences最新文献_第3页

Case Study 9: A 64-Year-Old Man With Rapidly Progressive Cognitive Impairment and Behavioral Changes. 案例研究9：一名64岁男性，快速进行性认知障碍和行为改变。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-02-18 DOI: 10.1176/appi.neuropsych.20240198

Syed N Kamal, Maria S Kryatova, Seth A Gale, Kirk R Daffner, David A Silbersweig, Scott M McGinnis, Barbara Schildkrout

引用次数: 0

Dementia With Lewy Bodies Phenocopy in a Case of RT-QuIC-Negative Creutzfeldt-Jakob Disease: Implications of Functional Anatomy. RT-QuIC 阴性克雅氏病病例中的路易体痴呆表型：功能解剖学的意义。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2024-07-11 DOI: 10.1176/appi.neuropsych.20230205

Molly K Wiggins, Emily P Pharr, Jennifer L Wood, Suzanne Craft, William T Harrison, James R Bateman

引用次数: 0

Myokines and the Brain: A Novel Neuromuscular Endocrine Loop. 肌因子与大脑：一种新的神经肌肉内分泌回路。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 DOI: 10.1176/appi.neuropsych.20240173

Wilfredo López-Ojeda, Robin A Hurley

引用次数: 0

Neuropsychiatric Vulnerabilities and Sequelae of Human Trafficking in the United States. 美国人口贩运的神经精神脆弱性和后遗症》（Neuropsychiatric Vulnerabilities and Sequelae of Human Trafficking in the United States.

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2024-11-19 DOI: 10.1176/appi.neuropsych.20240175

Mollie Gordon, Jade Evenstad, Komal Nathani, John Coverdale, Phuong Nguyen

引用次数: 0

The Population-Based Incidence and Prevalence of Catatonia. 以人群为基础的紧张症发病率和患病率。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-01-10 DOI: 10.1176/appi.neuropsych.20240072

James Luccarelli, Joshua R Smith, Mark Kalinich, Ali Amad, Jonathan P Rogers

{"title":"The Population-Based Incidence and Prevalence of Catatonia.","authors":"James Luccarelli, Joshua R Smith, Mark Kalinich, Ali Amad, Jonathan P Rogers","doi":"10.1176/appi.neuropsych.20240072","DOIUrl":"10.1176/appi.neuropsych.20240072","url":null,"abstract":"Objective: Catatonia is a neuropsychiatric disorder that is associated with a range of medical and psychiatric illnesses. Although many single-center studies have been conducted, uncertainty over the population-based incidence and prevalence of the disorder remains. This study reports on the incidence and prevalence rates of catatonia extrapolated from two large epidemiologic studies in the United Kingdom and United States.Methods: Incidence rates (defined as the number of catatonic episodes per 100,000 person-years) and prevalence rates (defined as the proportion of individuals with catatonia in a given year) were calculated from the two studies.Results: U.K. data showed an incidence of 4.34 (95% CI=3.98-4.72) catatonic episodes per 100,000 person-years with an average 1-year prevalence of 4.39 (95% CI=4.03-4.77) catatonic episodes per 100,000 persons. U.S. data revealed a 1-year prevalence of 5.15 (95% CI=5.08-5.23) catatonia-related hospitalizations per 100,000 persons.Conclusions: Catatonia is a rare disorder, qualifying as an orphan disease under both European Medicines Agency and U.S. Food and Drug Administration criteria. Further research is needed to rigorously define the epidemiology of catatonia in other populations.","PeriodicalId":16559,"journal":{"name":"Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"160-162"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

L266V MAPT Gene Mutation Associated With Frontotemporal Dementia, Progressive Supranuclear Palsy, and Corticobasal Syndrome. L266V MAPT基因突变与额颞叶痴呆、进行性核上性麻痹和皮质基底综合征相关

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-01-10 DOI: 10.1176/appi.neuropsych.20240128

Ana Maria Rivas-Grajales, Steve C Han, Ryan Wang, Patricia Greenstein, Ludy C Shih

引用次数: 0

Predictors of Antidepressant Use Among People With Multiple Sclerosis. 多发性硬化症患者使用抗抑郁药的预测因素。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1176/appi.neuropsych.20240096

David E Freedman, Jiwon Oh, Anthony Feinstein

{"title":"Predictors of Antidepressant Use Among People With Multiple Sclerosis.","authors":"David E Freedman, Jiwon Oh, Anthony Feinstein","doi":"10.1176/appi.neuropsych.20240096","DOIUrl":"10.1176/appi.neuropsych.20240096","url":null,"abstract":"Objective: Anxiety and depression are common among individuals with multiple sclerosis (MS) but are often undertreated. Little is known about factors that influence the odds of antidepressant treatment for MS. The authors aimed to identify predictors of antidepressant use among people with MS.Methods: A retrospective chart review was undertaken for a consecutive sample of 315 individuals with MS attending a tertiary neuropsychiatry clinic in Toronto. Predictor variables of antidepressant use included age, sex, MS duration and subtype, disease-modifying therapy use, psychotropic medication use, Expanded Disability Status Scale (EDSS) score (for neurological disability), Hospital Anxiety and Depression Scale subscale score (for anxiety and depression), and the abbreviated five-item Modified Fatigue Impact Scale (MFIS-5) score (for fatigue). Independent predictors of antidepressant use were identified with backward stepwise regression analyses (p<0.05).Results: Participants' mean±SD age was 45.5±11.4 years, 74% were female, the mean EDSS score was 2.8±1.9 out of 10.0, and 70% had a relapsing-remitting subtype of MS. Psychotropic medication use such as antipsychotics and anxiolytics (OR=1.77, p<0.01), increased EDSS scores (OR=1.20, p<0.01), and increased MFIS-5 scores (OR=1.11, p<0.01) independently predicted antidepressant use.Conclusions: Polypharmacy, neurological disability, and fatigue may increase the odds of antidepressant use among people with MS. These findings clarify differences between people with MS who use or do not use antidepressants, shedding light on the factors that may influence antidepressant use among people with MS.","PeriodicalId":16559,"journal":{"name":"Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"238-243"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated Prefrontal iTBS With Transauricular Vagus Nerve Stimulation for Functional Seizures and Depression: Case Report. 经耳迷走神经刺激加速前额叶iTBS治疗功能性癫痫和抑郁：病例报告。

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-03-26 DOI: 10.1176/appi.neuropsych.20240213

Charles Palmer, Noah Vieira, Elisabeth Collins, Morgan Dancy, Joseph Chasen, Mark S George

引用次数: 0

Case Study 8: A 70-Year-Old Man With Memory Loss, Wandering, and Inappropriate Behaviors. 案例研究8：一位70岁的老人，有失忆、徘徊和不恰当的行为。

IF 2.9 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1176/appi.neuropsych.20240125

Lakeshia C Gibson, Katherine A Krause, Seth A Gale, Barbara Schildkrout, Michael B Miller, Mel B Feany, David A Silbersweig, Kirk R Daffner, Hyun-Sik Yang, Scott M McGinnis

引用次数: 0

Quetiapine, Clozapine, and Pimavanserin Treatment Response in Monogenic Parkinson's Disease Psychosis: A Systematic Review. 喹硫平、氯氮平和皮马凡瑟林对单基因帕金森病精神病的治疗反应：系统回顾

IF 2.4 4区医学

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-01 Epub Date: 2024-07-22 DOI: 10.1176/appi.neuropsych.20230231

Mark Ainsley Colijn

{"title":"Quetiapine, Clozapine, and Pimavanserin Treatment Response in Monogenic Parkinson's Disease Psychosis: A Systematic Review.","authors":"Mark Ainsley Colijn","doi":"10.1176/appi.neuropsych.20230231","DOIUrl":"10.1176/appi.neuropsych.20230231","url":null,"abstract":"Psychotic symptoms frequently occur in idiopathic Parkinson's disease (PD) and often require treatment with antipsychotic therapy. Most antipsychotics have the potential to worsen the motor symptoms of PD; quetiapine, clozapine, and pimavanserin are commonly used for the treatment of idiopathic PD because these medications tend to be comparatively well tolerated. Although psychotic symptoms may also occur in monogenic forms of PD, no reviews have focused on the use of antipsychotic medications in this context. The objective of the present systematic review was to characterize the effectiveness and tolerability of quetiapine, clozapine, and pimavanserin in monogenic PD-associated psychosis. A literature search was performed with PubMed, Scopus, and Embase. The search yielded 24 eligible articles describing 30 individuals, although treatment response with respect to psychotic symptoms was described in only 11 cases; of these, six individuals experienced symptomatic improvement or remission (four with clozapine and two with quetiapine), two exhibited a poor therapeutic response (one to clozapine and one to quetiapine), and the other three responded initially to antipsychotic therapy before experiencing a recurrence of symptoms. The use of quetiapine and clozapine in GBA variant-associated PD is briefly reviewed separately. Notably, no reports of pimavanserin therapy were identified. In keeping with the idiopathic PD literature, relatively low doses of medication were used in most cases. Lastly, side effects were rarely reported. Although quetiapine and particularly clozapine may be effective and well tolerated in the treatment of monogenic PD psychosis, this review highlights the paucity of available evidence to guide clinical decision making in this context.","PeriodicalId":16559,"journal":{"name":"Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"6-13"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0