The Population-Based Incidence and Prevalence of Catatonia.

IF 2.4 4区医学 Q2 CLINICAL NEUROLOGY

Journal of Neuropsychiatry and Clinical Neurosciences Pub Date : 2025-01-10 DOI:10.1176/appi.neuropsych.20240072

James Luccarelli, Joshua R Smith, Mark Kalinich, Ali Amad, Jonathan P Rogers

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引用次数: 0

Abstract

Objective: Catatonia is a neuropsychiatric disorder that is associated with a range of medical and psychiatric illnesses. Although many single-center studies have been conducted, uncertainty over the population-based incidence and prevalence of the disorder remains. This study reports on the incidence and prevalence rates of catatonia extrapolated from two large epidemiologic studies in the United Kingdom and United States.

Methods: Incidence rates (defined as the number of catatonic episodes per 100,000 person-years) and prevalence rates (defined as the proportion of individuals with catatonia in a given year) were calculated from the two studies.

Results: U.K. data showed an incidence of 4.34 (95% CI=3.98-4.72) catatonic episodes per 100,000 person-years with an average 1-year prevalence of 4.39 (95% CI=4.03-4.77) catatonic episodes per 100,000 persons. U.S. data revealed a 1-year prevalence of 5.15 (95% CI=5.08-5.23) catatonia-related hospitalizations per 100,000 persons.

Conclusions: Catatonia is a rare disorder, qualifying as an orphan disease under both European Medicines Agency and U.S. Food and Drug Administration criteria. Further research is needed to rigorously define the epidemiology of catatonia in other populations.

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以人群为基础的紧张症发病率和患病率。

目的：紧张症是一种神经精神障碍，与一系列医学和精神疾病有关。尽管已经进行了许多单中心研究，但基于人群的发病率和患病率仍然不确定。本研究报告从英国和美国的两项大型流行病学研究中推断出紧张症的发病率和患病率。方法：从这两项研究中计算发病率（定义为每10万人年紧张症发作的次数）和患病率（定义为某一年患有紧张症的个体的比例）。结果：英国数据显示，每10万人年紧张性发作4.34次（95% CI=3.98-4.72），平均1年患病率为每10万人4.39次（95% CI=4.03-4.77）。美国数据显示，每10万人中有5.15人（95% CI=5.08-5.23）因紧张症住院。结论：紧张症是一种罕见的疾病，符合欧洲药品管理局和美国食品和药物管理局的孤儿病标准。需要进一步的研究来严格定义紧张症在其他人群中的流行病学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuropsychiatry and Clinical Neurosciences 医学-精神病学

CiteScore

5.30

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： As the official Journal of the American Neuropsychiatric Association, the premier North American organization of clinicians, scientists, and educators specializing in behavioral neurology & neuropsychiatry, neuropsychology, and the clinical neurosciences, the Journal of Neuropsychiatry and Clinical Neurosciences (JNCN) aims to publish works that advance the science of brain-behavior relationships, the care of persons and families affected by neurodevelopmental, acquired neurological, and neurodegenerative conditions, and education and training in behavioral neurology & neuropsychiatry. JNCN publishes peer-reviewed articles on the cognitive, emotional, and behavioral manifestations of neurological conditions, the structural and functional neuroanatomy of idiopathic psychiatric disorders, and the clinical and educational applications and public health implications of scientific advances in these areas. The Journal features systematic reviews and meta-analyses, narrative reviews, original research articles, scholarly considerations of treatment and educational challenges in behavioral neurology & neuropsychiatry, analyses and commentaries on advances and emerging trends in the field, international perspectives on neuropsychiatry, opinions and introspections, case reports that inform on the structural and functional bases of neuropsychiatric conditions, and classic pieces from the field’s rich history.