Journal of nuclear medicine technology最新文献

{"title":"⁹⁰Y SIR-Spheres Activity Measurement with New SIROS D-Vial Delivery Kit.","authors":"Benjamin P Lopez, S Cheenu Kappadath","doi":"10.2967/jnmt.124.267413","DOIUrl":"10.2967/jnmt.124.267413","url":null,"abstract":"<p><p>A new ⁹⁰Y SIR-Spheres delivery kit (SIROS D-vial and shield) has been introduced with a different physical form from the legacy V-Vial kit. Here, we establish the dose calibrator settings and exposure-rate-to-activity conversion factor to assay ⁹⁰Y SIR-Spheres activity in the new SIROS kit. <b>Methods:</b> Eight D-vials with initial ⁹⁰Y activities from 1.2 to 6.6 GBq within acrylic shields were assayed with dose calibrators and exposure-rate meters until activities decayed to approximately 0.1 GBq. The dose calibrator settings resulting in the lowest median activity errors and the best-fit slope of exposure rate versus activity were identified. <b>Results:</b> SIROS D-vial ⁹⁰Y activity can be accurately and reliably estimated directly using setting 51 × 10 on both the CRC-15R and the CRC-55tR dose calibrators (errors within ±0.5%) and indirectly with an exposure-rate reading at 30 cm using conversion factor 0.664 ± 0.003 GBq/(mR/h) (<i>R</i> ² = 0.985). <b>Conclusion:</b> Dose calibrator settings and exposure-rate-to-activity conversion factor for ⁹⁰Y activity assays with new SIROS kit should be updated from legacy V-Vial parameters to avoid an approximately 10% underestimation.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"256-260"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can a Carbonated Lemon Drink Reduce Extracardiac Activity in Myocardial Perfusion Imaging?","authors":"Nora Al-Somali, Hossam El-Zeftawy, Salman Al-Qurashi, Nabeel Mishah, Jose Norwin Catipay, Leen Albalbeesi, Yasser Al-Eatany, Narjes Al-Alahmadii, Ali Alghamdi, Ahmed A Osman, Nadia Batawil","doi":"10.2967/jnmt.124.267965","DOIUrl":"10.2967/jnmt.124.267965","url":null,"abstract":"<p><p>Myocardial perfusion imaging (MPI) provides physiologic and functional information about the heart muscle and its blood flow. Extracardiac radioactivity can interfere with visualization of the inferior wall of the myocardium, leading to poor-quality images, difficulties in interpretation, and delays in routine practice. This study aimed to identify the efficiency of having the patient consume a carbonated lemon drink to minimize the extracardiac radioactivity of ^99mTc-sestamibi in comparison to ^99mTc-tetrofosmin during MPI. <b>Methods:</b> This was a retrospective study that recruited 158 patients with known or suspected coronary artery disease referred to undergo ^99mTc-sestamibi or ^99mTc-tetrofosmin rest/stress single-day MPI. The patients were divided into 2 groups of mixed sexes and different ages. The first group comprised 78 patients injected with ^99mTc-sestamibi, and the second group comprised 80 patients injected with ^99mTc-tetrofosmin. For both groups, the patients drank 30 mL of fresh lemon juice diluted with 150 mL of soda water, and then we gave the patients about 100 mL of straight soda water, before imaging for both the rest and the stress phases. <b>Results:</b> Generally, in both groups, the ^99mTc-tetrofosmin produced a good-quality image in comparison with the ^99mTc-sestamibi. The mean rank of the total score for ^99mTc-tetrofosmin (62.75) was less than that for ^99mTc-sestamibi (96.68), and this difference was highly statistically significant (<i>P</i> = 0.000). There were statistically significant differences in the ratios and mean ranks for both groups in favor of ^99mTc-tetrofosmin in patients having coronary artery disease. <b>Conclusion:</b> The use of a carbonated lemon drink minimizes extracardiac activity from both ^99mTc-labeled MPI radiopharmaceuticals. This finding was more statistically significant for ^99mTc-tetrofosmin MPI, providing better image quality and earlier imaging in both the rest and the stress phases because of faster hepatobiliary clearance.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"239-246"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand.","authors":"Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich","doi":"10.2967/jnmt.124.267576","DOIUrl":"10.2967/jnmt.124.267576","url":null,"abstract":"<p><p>Diagnostic reference levels (DRLs) are an important tool for controlling radiation exposure and ensuring safety in medical applications. In Thailand, DRL data have been gathered and established for nuclear medicine diagnostics since 2021. However, there is a lack of information on PET imaging examinations. At the National Cyclotron and PET Scan Centre, Chulabhorn Hospital, radiopharmaceuticals are produced for medical imaging and research, and a wide range of PET/CT and PET/MRI examinations are performed. Our objective was to investigate the administered activity of radiopharmaceuticals in patients undergoing PET imaging, especially the existing data on DRLs in medical diagnostic imaging. <b>Methods:</b> This was a retrospective study on nuclear medicine patients at the National Cyclotron and PET Scan Centre in 2023. Statistical analysis, including the mean and the 75th percentile values, was conducted to determine DRLs according to the International Commission on Radiological Protection guidelines. <b>Results:</b> The center performed 8,711 PET/CT and PET/MRI studies with 13 protocols in 2023. The most commonly administered activity was ¹⁸F-FDG in oncology and neurology examinations, with DRLs of 186.11 and 136.16 MBq, respectively. These values were notably almost twice lower than several reports in other countries. <b>Conclusion:</b> There is a lack of comprehensive data on most DRLs for PET imaging at this center because of the nonwidespread use of several radiopharmaceuticals. However, the lower DRLs for ¹⁸F-FDG can highlight the need for ongoing investigation toward the establishment of local DRLs, as well as assurance on the safety and efficiency of radiation used in nuclear medicine.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"261-266"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain Death Scintigraphy: Do Not Blow the Flow.","authors":"Julie D Bolin","doi":"10.2967/jnmt.124.267894","DOIUrl":"10.2967/jnmt.124.267894","url":null,"abstract":"<p><p>Brain death denotes the loss of function in both the cerebrum and the brain stem, leading to coma, absence of spontaneous respiration in the setting of adequate stimulus, and the cessation of all brain stem reflexes. Although spinal reflexes such as deep tendon, plantar flexion, and withdrawal reflexes may persist, recovery is not possible. The cessation of brain function qualifies as death because of its central role in coordinating vital bodily functions. Although brain death is largely determined by a clinical and neurologic examination, confounding variables may necessitate ancillary testing such as cerebral brain perfusion imaging.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"192-198"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal Cortical Imaging.","authors":"Mary Beth Farrell","doi":"10.2967/jnmt.124.268301","DOIUrl":"10.2967/jnmt.124.268301","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"205-207"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of the Clinical and Technical Aspects of ^99mTc-Dimercaptosuccinic Acid Renal Imaging: The Comeback \"Kit\".","authors":"Ruth Lim, Neha Kwatra, Valentina Ferrer Valencia, Katelyn N Collins, Reza Vali, Frederic H Fahey, S Ted Treves","doi":"10.2967/jnmt.123.267185","DOIUrl":"10.2967/jnmt.123.267185","url":null,"abstract":"<p><p>^99mTc-labeled dimercaptosuccinic acid (^99mTc-DMSA) imaging is a well-established and highly sensitive method for the diagnosis of several renal cortical disorders affecting children and adults. Beginning in 2014, ^99mTc-DMSA availability was severely impaired when it was added to the Drug Shortages List of the U.S. Food and Drug Administration and was commercially unavailable thereafter. The agent shortage negatively impacted practitioners' ability to evaluate renal cortical defects in children and adults and changed renal imaging practice. A survey among pediatric nuclear medicine clinicians confirmed the clinical need for ^99mTc-DMSA. Finally, in early 2023 the Food and Drug Administration again approved ^99mTc-DMSA in the United States. During the ^99mTc-DMSA shortage, established practitioners may not have had the opportunity of using ^99mTc-DMSA as they were accustomed in their experience. Also, newer imaging specialists and referring physicians and technologists may not have benefited from having ^99mTc-DMSA in their training. Therefore, it is time to bring back ^99mTc-DMSA into the armamentarium of imaging methods available to evaluate regional cortical renal function.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"199-204"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing Communication Support Material for Sharing Information with Patients Undergoing an ¹⁸F-FDG PET/CT Examination.","authors":"Camilla Andersson, Berit Möller-Christensen","doi":"10.2967/jnmt.124.267672","DOIUrl":"10.2967/jnmt.124.267672","url":null,"abstract":"<p><p>Our aim was to develop communication support material for information sharing related to an ¹⁸F-FDG PET/CT examination. <b>Methods:</b> The study had a qualitative design adapting a multiphase structure. A prototype of communication support material consisting of illustrations and text related to an ¹⁸F-FDG PET/CT examination was developed. Interviews were conducted with patients scheduled for an ¹⁸F-FDG PET/CT examination for the first time, and questionnaires were collected from health care professionals with experience in ¹⁸F-FDG PET/CT. The communication support material was revised until consensus was reached about it. <b>Results:</b> The results are based on interviews with patients (<i>n</i> = 10) and questionnaires collected from health care professionals (<i>n</i> = 9). The overall theme revealed that patient information about an ¹⁸F-FDG PET/CT examination is a balancing act between text and illustrations. The analysis showed 2 categories: \"illustrations as a complement\" and \"easy-to-understand layout.\" <b>Conclusion:</b> The participants strengthened the development of the communication support material by bringing in valuable viewpoints from various perspectives. The results support a person-centered approach in which information about an ¹⁸F-FDG PET/CT examination can be adapted to each patient's needs as a balancing act between text and illustrations.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"234-238"},"PeriodicalIF":1.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/CT Imaging in Lung Cancer.","authors":"Kelli E Schlarbaum","doi":"10.2967/jnmt.124.267843","DOIUrl":"https://doi.org/10.2967/jnmt.124.267843","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"52 2","pages":"91-101"},"PeriodicalIF":1.3,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>JNMT</i> Outstanding Articles for 2023.","authors":"Kathy S Thomas","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"52 2","pages":"8A"},"PeriodicalIF":1.3,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nuclear Medicine and Theranostics: A Year of Remarkable Achievements and Global Engagement.","authors":"Dmitry Beyder","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"52 2","pages":"9A-10A"},"PeriodicalIF":1.3,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}