Journal of nuclear medicine technology最新文献

{"title":"When in Doubt, Add SPECT/CT: A Case of Mistaken Identity","authors":"Justin G. Peacock, Amanda M. Adams","doi":"10.2967/jnmt.123.266795","DOIUrl":"https://doi.org/10.2967/jnmt.123.266795","url":null,"abstract":"A 63-y-old woman with a history of breast cancer presented with concerns of osseous metastasis. Initial whole-body planar bone scintigraphy revealed a focus of concern overlying the sternum. SPECT/CT images revealed the anomaly — localized activity in the needleless hub attached to the chemotherapy port. If not for the precision of SPECT/CT, such a rare artifact could have led to a false-positive diagnosis, particularly impactful in breast cancer patients. This case emphasizes the critical role of SPECT/CT in accurate diagnoses.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"57 4","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An International Survey Investigating the Incidence and Management of Brown Fat Uptake on18F-FDG PET/CT at Children’s Hospitals and Interventions for Mitigation","authors":"William C. Gaylord, Andrew T. Trout, Anthony N. Audino, Jennifer A. Belsky","doi":"10.2967/jnmt.123.266536","DOIUrl":"https://doi.org/10.2967/jnmt.123.266536","url":null,"abstract":"Brown fat can present challenges in patients with cancer who undergo 18 F-FDG PET scans. Uptake of 18 F-FDG by brown fat can obscure or appear similar to active oncologic lesions, causing clinical challenges in PET interpretation. Small, retrospective studies have reported environmental and pharmacologic interventions for suppressing brown fat uptake on PET; however, there is no clear consensus on best practices. We sought to characterize practice patterns for strategies to mitigate brown fat uptake of 18 F-FDG during PET scanning. Methods: A survey was developed and distributed via e-mail LISTSERV to members of the Children ’ s Oncology Group diagnostic imaging committee, the Society for Nuclear Medicine and Molecular Imaging pediatric imaging council, and the Society of Chiefs of Radiology at Children ’ s Hospitals between April 2022 and February 2023. Responses were stored anony-mously in REDCap, aggregated, and summarized using descriptive statistics. Results: Fifty-fi ve complete responses were submitted: 51 (93%) faculty and fellow-level physicians, 2 (4%) technologists, and 2 (4%) respondents not reporting their rank. There were 43 unique institutions represented, including 5 (12%) outside the United States. Thirty-eight of 41 (93%) institutions that responded on environmental interventions reported using warm blankets in the infusion and scanning rooms. Less than a third ( n 5 13, 30%) of institutions reported use of a pharmacologic intervention, with propranolol ( n 5 5, 38%) being most common, followed by fentanyl ( n 5 4, 31%), diazepam ( n 5 2, 15%), and diazepam plus pro-pranolol ( n 5 2, 15%). Selection criteria for pharmacologic intervention varied, with the most common criterion being brown fat uptake on a prior scan ( n 5 6, 45%). Conclusion: Clinical practices to mitigate brown fat uptake on pediatric 18 F-FDG PET vary widely. Simple environmental interventions including warm blan-kets or increasing the temperature of the injection and scanning rooms were not universally reported. Less than a third of institutions use pharmacologic agents for brown fat mitigation.","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"128 3","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical Aspects of Nuclear Medicine Ventriculoperitoneal Shunt Evaluation.","authors":"Michael M Graham","doi":"10.2967/jnmt.123.266203","DOIUrl":"10.2967/jnmt.123.266203","url":null,"abstract":"<p><p>The radionuclide ventriculoperitoneal shunt evaluation study is a simple test that involves injecting a small volume of radionuclide into the shunt reservoir and then observing its disappearance using dynamic γ-camera imaging. Although it seems simple, there are several potential pitfalls that can result in a misinterpreted or uninterpretable study. This paper is a detailed description of how to avoid the pitfalls and also how to interpret the results.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"271-276"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing ePortfolio Within the Nuclear Medicine Technology Program.","authors":"Grace Wenzler, George Patchoros, Jordi Getman-Eraso","doi":"10.2967/jnmt.123.265969","DOIUrl":"10.2967/jnmt.123.265969","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"302-306"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventricular Shunt Patency.","authors":"Michael Graham","doi":"10.2967/jnmt.123.266765","DOIUrl":"10.2967/jnmt.123.266765","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"277-278"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilation/Perfusion Lung Scan Safety Statement in the Current Coronavirus Disease 2019 Environment.","authors":"Sara G Johnson","doi":"10.2967/jnmt.123.266734","DOIUrl":"10.2967/jnmt.123.266734","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"288-289"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cervical Ganglioneuroblastoma Diagnosed by ⁶⁸Ga-DOTATOC PET/CT in a Child with Opsoclonus Myoclonus Syndrome.","authors":"Kusai Al-Muqbel, Hamza Alardah, Ruba Al-Smadi, Sohaib Al-Khatib, Raya Abughanmi","doi":"10.2967/jnmt.123.265776","DOIUrl":"10.2967/jnmt.123.265776","url":null,"abstract":"<p><p>We performed a ⁶⁸Ga-DOTATOC PET/CT scan on a 25-mo-old female patient who presented with opsoclonus myoclonus ataxia syndrome and had negative initial anatomic imaging. The scan showed a somatostatin receptor-overexpressing cervical tumor in favor of a cervical neuroendocrine tumor, with subsequent histopathologic findings of ganglioneuroblastoma.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"337-338"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"⁹⁰Y Contamination in the Interventional Radiology Suite: VARSKIN Estimation of Skin and Eye Injury and Review of Mitigation Strategies.","authors":"Michael Arseneault, George Mawko, Robert J Abraham","doi":"10.2967/jnmt.122.265108","DOIUrl":"10.2967/jnmt.122.265108","url":null,"abstract":"<p><p>Our objective was to demonstrate, through computer simulations, radiation exposure levels from a ⁹⁰Y contamination event during radioembolization procedures to calculate the radiation doses from various contamination scenarios. We also provide reasonable safety protocols to prevent contamination and minimize radiation exposure during decontamination. <b>Methods:</b> Simulations were performed using the computer code VARSKIN+, version 1.0, to determine the amount of radiation exposure resulting from different contamination scenarios. <b>Results:</b> The annual radiation dose limit to the skin and the lens of the eye was exceeded within 23 s of exposure to a 44-MBq droplet. Double layers of surgical gloves and level 3 gowns provided some attenuation of radiation from ⁹⁰Y contamination by reducing the dose rate by 39% and 44%, respectively. Two layers of surgical gloves offered the best ratio of radiation protection without compromising dexterity. <b>Conclusion:</b> This study demonstrated that radiation exposures during ⁹⁰Y spills or contamination events can be considerable. Interventional radiology and nuclear medicine personnel must be mindful of the risks, follow strategies to prevent spills, and be familiar with recommended decontamination procedures for spills in the interventional radiology suite.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"290-295"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10069951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ChatGPT and Patient Information in Nuclear Medicine: GPT-3.5 Versus GPT-4.","authors":"Geoff Currie, Stephanie Robbie, Peter Tually","doi":"10.2967/jnmt.123.266151","DOIUrl":"10.2967/jnmt.123.266151","url":null,"abstract":"<p><p>The GPT-3.5-powered ChatGPT was released in late November 2022 powered by the generative pretrained transformer (GPT) version 3.5. It has emerged as a readily accessible source of patient information ahead of medical procedures. Although ChatGPT has purported benefits for supporting patient education and information, actual capability has not been evaluated. Moreover, the March 2023 emergence of paid subscription access to GPT-4 promises further enhanced capabilities requiring evaluation. <b>Methods:</b> ChatGPT was used to generate patient information sheets suitable for gaining informed consent for 7 common procedures in nuclear medicine. Responses were generated independently for both GPT-3.5 and GPT-4 architectures. Specific procedures were selected that had a long-standing history of use to avoid any bias associated with the September 2021 learning cutoff that constrains both GPT-3.5 and GPT-4 architectures. Each information sheet was independently evaluated by 3 expert assessors and ranked on the basis of accuracy, appropriateness, currency, and fitness for purpose. <b>Results:</b> ChatGPT powered by GPT-3.5 provided patient information that was appropriate in terms of being patient-facing but lacked accuracy and currency and omitted important information. GPT-3.5 produced patient information deemed not fit for the purpose. GPT-4 provided patient information enhanced across appropriateness, accuracy, and currency, despite some omission of information. GPT-4 produced patient information that was largely fit for the purpose. <b>Conclusion:</b> Although ChatGPT powered by GPT-3.5 is accessible and provides plausible patient information, inaccuracies and omissions present a risk to patients and informed consent. Conversely, GPT-4 is more accurate and fit for the purpose but, at the time of writing, was available only through a paid subscription.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"307-313"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10224669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differentiation of Discordant Lesions on Dual-Tracer PET/CT (⁶⁸Ga-PSMA-11 and ¹⁸F-FDG) in Prostate Carcinoma: Diagnosis of Second Primary Malignancies.","authors":"Ashwini Chalikandy, Subhash Yadav, Sandip Basu","doi":"10.2967/jnmt.123.265779","DOIUrl":"10.2967/jnmt.123.265779","url":null,"abstract":"<p><p>We present 2 cases of metastatic castration-resistant prostate carcinoma with discordant lesions on dual-tracer PET/CT (⁶⁸Ga-PSMA-11 and ¹⁸F-FDG PET/CT), which on subsequent histopathologic evaluation revealed second primary malignancies of combined hepatocellular carcinoma and cholangiocarcinoma and poorly differentiated squamous cell carcinoma. These case illustrations emphasize the need to evaluate discordant lesions on dual-tracer PET/CT, which can lead to early diagnosis of second primary malignancies and thereby can provide better management in these patients.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"339-342"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10069945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}