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The Role of [99mTc]Tc-Sestamibi in Functional Imaging of the Iodine-Loaded Thyroid Gland. [99mTc]Tc-Sestamibi在碘负荷甲状腺功能成像中的作用。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.265665
Sokratis El Mantani Ordoulidis, Maria Siampanopoulou
{"title":"The Role of [<sup>99m</sup>Tc]Tc-Sestamibi in Functional Imaging of the Iodine-Loaded Thyroid Gland.","authors":"Sokratis El Mantani Ordoulidis, Maria Siampanopoulou","doi":"10.2967/jnmt.123.265665","DOIUrl":"10.2967/jnmt.123.265665","url":null,"abstract":"<p><p>Due to high iodine loading from iodinated contrast media, the thyroid uptake of common radiopharmaceuticals ([<sup>99m</sup>Tc]NaTcO<sub>4</sub> and [<sup>123</sup>I]NaI) can be influenced up to 2 mo after administration. In such cases, and generally when differential diagnosis between productive and destructive thyrotoxicosis is necessary, [<sup>99m</sup>Tc]Tc-sestamibi scintigraphy could be an option. This case highlights the role of [<sup>99m</sup>Tc]Tc-sestamibi in the evaluation of thyrotoxicosis in a patient with a blocked thyroid gland as a result of stable iodine saturation.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"331-332"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical Challenges in Pluvicto Therapy: Incontinent and Anticoagulated Patients. 普立维托治疗的关键挑战:尿失禁和抗凝患者。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266482
James R Crowley
{"title":"Critical Challenges in Pluvicto Therapy: Incontinent and Anticoagulated Patients.","authors":"James R Crowley","doi":"10.2967/jnmt.123.266482","DOIUrl":"10.2967/jnmt.123.266482","url":null,"abstract":"<p><p>As molecular therapy continues to grow, unanticipated challenges may arise, requiring the institution's therapeutic team to reevaluate its therapeutic protocol to identify and address potential situations and challenges that may occur. This practical pointer will focus on the novel prostate cancer therapy Pluvicto (<sup>177</sup>Lu-vipivotide tetraxetan) and 2 unique situations and challenges of treating patients at the Theranostic Center at Carilion Clinic, an outpatient facility dedicated to targeted molecular therapy.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"279-281"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ChatGPT in Nuclear Medicine: Unveiling the Pros and Cons. ChatGPT在核医学：揭开利弊。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266070
Jasim Jaleel, Sambit Sagar, Rakesh Kumar
{"title":"ChatGPT in Nuclear Medicine: Unveiling the Pros and Cons.","authors":"Jasim Jaleel, Sambit Sagar, Rakesh Kumar","doi":"10.2967/jnmt.123.266070","DOIUrl":"10.2967/jnmt.123.266070","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"343-344"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49678546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GPT-4 in Nuclear Medicine Education: Does It Outperform GPT-3.5? 核医学教育中的GPT-4：它的表现优于GPT-3.5吗？
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266485
Geoffrey M Currie
{"title":"GPT-4 in Nuclear Medicine Education: Does It Outperform GPT-3.5?","authors":"Geoffrey M Currie","doi":"10.2967/jnmt.123.266485","DOIUrl":"10.2967/jnmt.123.266485","url":null,"abstract":"<p><p>The emergence of ChatGPT has challenged academic integrity in teaching institutions, including those providing nuclear medicine training. Although previous evaluations of ChatGPT have suggested a limited scope for academic writing, the March 2023 release of generative pretrained transformer (GPT)-4 promises enhanced capabilities that require evaluation. <b>Methods:</b> Examinations (final and calculation) and written assignments for nuclear medicine subjects were tested using GPT-3.5 and GPT-4. GPT-3.5 and GPT-4 responses were evaluated by Turnitin software for artificial intelligence scores, marked against standardized rubrics, and compared with the mean performance of student cohorts. <b>Results:</b> ChatGPT powered by GPT-3.5 performed poorly in calculation examinations (31.4%), compared with GPT-4 (59.1%). GPT-3.5 failed each of 3 written tasks (39.9%), whereas GPT-4 passed each task (56.3%). <b>Conclusion:</b> Although GPT-3.5 poses a minimal risk to academic integrity, its usefulness as a cheating tool can be significantly enhanced by GPT-4 but remains prone to hallucination and fabrication.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"314-317"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49678557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ChatGPT in Nuclear Medicine Education. 核医学教育中的ChatGPT。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266334
Amnuay Kleebayoon, Viroj Wiwanitkit
{"title":"ChatGPT in Nuclear Medicine Education.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.2967/jnmt.123.266334","DOIUrl":"10.2967/jnmt.123.266334","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"344"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49678545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of 18F-FDG PET/CT in Assessment of Disease Extent and Response to Treatment in Xanthoma Disseminatum. 18F-FDG PET/CT在评估广泛性黄瘤疾病程度和治疗反应中的应用
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266162
Kunal Ramesh Chandekar, Swayamjeet Satapathy, Ananya Sharma, Neha Taneja, Madhavi Tripathi, Chandrasekhar Bal
{"title":"Utility of <sup>18</sup>F-FDG PET/CT in Assessment of Disease Extent and Response to Treatment in Xanthoma Disseminatum.","authors":"Kunal Ramesh Chandekar, Swayamjeet Satapathy, Ananya Sharma, Neha Taneja, Madhavi Tripathi, Chandrasekhar Bal","doi":"10.2967/jnmt.123.266162","DOIUrl":"10.2967/jnmt.123.266162","url":null,"abstract":"<p><p>The clinical utility of <sup>18</sup>F-FDG PET/CT is being increasingly recognized in histiocytic disorders. We report the case of a 23-y-old woman who presented with slowly progressive, yellowish-brown papules, plaques, and nodules over her face and flexures. Besides the multiple cutaneous lesions, lesions of the brain, stomach, gallbladder, and marrow were additionally revealed by baseline <sup>18</sup>F-FDG PET/CT. Skin biopsy and the overall clinical picture were consistent with xanthoma disseminatum. Subsequent PET/CT after cladribine therapy revealed a decrease in the extent and metabolic activity of most lesions, suggestive of a favorable response. This case report highlights the potential role of <sup>18</sup>F-FDG PET/CT in the accurate assessment of disease extent and posttreatment response in rare histiocytic disorders.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"335-336"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10224666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uterine Metastasis Presenting as Abnormal Uterine Bleeding in a Case of Primary Breast Cancer Identified on 18F-FDG PET/CT. 18F-FDG PET/CT诊断原发性乳腺癌子宫转移表现为异常子宫出血1例
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266221
Parneet Singh, Sai Sradha Patro, Tejasvini Singhal, Girish Kumar Parida, Kanhaiyalal Agrawal
{"title":"Uterine Metastasis Presenting as Abnormal Uterine Bleeding in a Case of Primary Breast Cancer Identified on <sup>18</sup>F-FDG PET/CT.","authors":"Parneet Singh, Sai Sradha Patro, Tejasvini Singhal, Girish Kumar Parida, Kanhaiyalal Agrawal","doi":"10.2967/jnmt.123.266221","DOIUrl":"10.2967/jnmt.123.266221","url":null,"abstract":"<p><p>Metastases to the female genital tract are rare, especially from extragenital primaries. The most common extragenital sites associated with genital metastasis are the gastrointestinal tract (37.6%) followed by the breast (34.9%). It is crucial to differentiate primary from metastatic involvement of the uterus for appropriate patient management. We present one such case of endometrial metastasis in a patient who presented clinically with abnormal uterine bleeding and was diagnosed with primary breast cancer via <sup>18</sup>F-FDG PET/CT.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"333-334"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurotheranostics: The Next Frontier for Health Span. 神经治疗:健康跨度的下一个前沿。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.265502
Meryam A Losee, John P Seibyl, Phillip H Kuo
{"title":"Neurotheranostics: The Next Frontier for Health Span.","authors":"Meryam A Losee, John P Seibyl, Phillip H Kuo","doi":"10.2967/jnmt.123.265502","DOIUrl":"10.2967/jnmt.123.265502","url":null,"abstract":"<p><p>With an aging U.S. population, advancements in the treatment of Alzheimer disease (AD) and other neurodegenerative diseases are key to the maximization of health span. The recent approval of 2 antiamyloid antibodies, which decrease brain amyloid load, places us on the cusp of breakthrough therapies that target the mechanism of the disease rather than just treating the symptoms. Although the trials that led to these approvals studied patients with mild early symptoms, multiple ongoing trials have enrolled cognitively normal patients screened for AD biomarkers including risk factors for amyloid positivity, family history, and genetic markers. Thus, amyloid PET can help identify an at-risk population that can be enrolled for antiamyloid therapy to prevent AD symptoms from ever developing. In this review, we examine the paradigm of neurotheranostics and how PET biomarkers of amyloid, tau, inflammation, and neurodegeneration could characterize the pathologic stage of AD and therefore allow for personalized therapy.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"266-270"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Quick Guide to Writing a Teaching Case Study. 撰写教学案例研究的快速指南。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.266660
Mary Beth Farrell
{"title":"A Quick Guide to Writing a Teaching Case Study.","authors":"Mary Beth Farrell","doi":"10.2967/jnmt.123.266660","DOIUrl":"10.2967/jnmt.123.266660","url":null,"abstract":"<p><p>Case studies published in the <i>Journal of Nuclear Medicine Technology</i> are brief chronologic or logical descriptions of a clinical experience that aim to share a technical outcome associated with an instrumentation or patient care scenario or demonstrate a unique finding associated with a nuclear medicine procedure. Although brief by necessity, case studies provide enough relevant detail to educate the reader about a clinical condition coupled with a diagnostic or therapeutic procedure. Case studies do not have to be about bizarre clinical conditions. Case studies can be about quality issues that directly impact the imaging or therapeutic procedure, protocol modifications when a clinical scenario requires out-of-the-box decisions, new techniques developed to address unique or difficult situations, or something as simple as an artifact that resulted in an unusual image finding. The sections of a case study, including the introduction, case report, discussion, and conclusion, are explained. The goal of this article is to teach new authors how to write a teaching case study.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"323-326"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging Pathway of a Pediatric Patient with Succinate Dehydrogenase B-Deficient Paraganglioma. 小儿琥珀酸脱氢酶b缺乏症副神经节瘤的影像学表现。
IF 1.3
Journal of nuclear medicine technology Pub Date : 2023-12-05 DOI: 10.2967/jnmt.123.265655
Stephen Edmonds, Jennifer Davidson, Rosanne Joseph, Madhusudan Vyas
{"title":"Imaging Pathway of a Pediatric Patient with Succinate Dehydrogenase B-Deficient Paraganglioma.","authors":"Stephen Edmonds, Jennifer Davidson, Rosanne Joseph, Madhusudan Vyas","doi":"10.2967/jnmt.123.265655","DOIUrl":"10.2967/jnmt.123.265655","url":null,"abstract":"<p><p>Pheochromocytoma and paraganglioma are rare in children, at only 1 in every 50,000 cases. Even though some cases are sporadic, they have been connected to syndromes such as von Hippel-Lindau, multiple endocrine neoplasia types IIa and IIb, neurofibromatosis type 1, and hereditary pheochromocytoma-paraganglioma syndromes. A genetic mutation causes around 60% of pheochromocytomas and paragangliomas in children under 18. <b>Methods:</b> A 15-y-old child with a 6-y history of back discomfort is presented. The justification for using 2 functional imaging modalities, <sup>68</sup>Ga-DOTATATE PET/CT and <sup>123</sup>I-<i>meta</i>-iodobenzylguanidine SPECT/CT, is examined in this case study. We reviewed the patients' journey since the first referral for imaging. <b>Results:</b> Delaying the molecular imaging modalities has affected patients' overall diagnosis and applied treatment outcomes. <b>Conclusion:</b> This case study investigates the potential for the earlier use of various diagnostic modalities in conjunction with diagnostic testing to facilitate an earlier diagnosis. However, since this study is based solely on imaging and lacks access to the patient's clinical or family history, factors such as potential inequities in health-care facilities, health literacy, and socioeconomic status are not addressed. It is essential to acknowledge these influences as they contribute to the inequitable access to health-care settings in New Zealand.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"318-322"},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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