Journal of nuclear medicine technology最新文献

{"title":"A Quick Guide to Writing a Teaching Case Study.","authors":"Mary Beth Farrell","doi":"10.2967/jnmt.123.266660","DOIUrl":"10.2967/jnmt.123.266660","url":null,"abstract":"<p><p>Case studies published in the <i>Journal of Nuclear Medicine Technology</i> are brief chronologic or logical descriptions of a clinical experience that aim to share a technical outcome associated with an instrumentation or patient care scenario or demonstrate a unique finding associated with a nuclear medicine procedure. Although brief by necessity, case studies provide enough relevant detail to educate the reader about a clinical condition coupled with a diagnostic or therapeutic procedure. Case studies do not have to be about bizarre clinical conditions. Case studies can be about quality issues that directly impact the imaging or therapeutic procedure, protocol modifications when a clinical scenario requires out-of-the-box decisions, new techniques developed to address unique or difficult situations, or something as simple as an artifact that resulted in an unusual image finding. The sections of a case study, including the introduction, case report, discussion, and conclusion, are explained. The goal of this article is to teach new authors how to write a teaching case study.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the Importance of Applying Various Methods of Calculation in Determining the Blood-Absorbed Dose for Patients with Differentiated Thyroid Carcinoma.","authors":"Issa A Al-Shakhrah","doi":"10.2967/jnmt.122.265214","DOIUrl":"10.2967/jnmt.122.265214","url":null,"abstract":"<p><p>The objective was to compare estimated total blood-absorbed doses obtained by applying 4 methods to the same group of patients. In addition, these results were compared with those for the patients of other researchers, who used various other techniques over a period of more than 20 y. <b>Methods:</b> Twenty-seven patients (22 women and 5 men) with differentiated thyroid carcinoma were enrolled in the study. Whole-body measurements were performed as conjugate-view (anterior and posterior) counts by scintillation camera imaging. All patients received 3.7 GBq of ¹³¹I for thyroid ablation. <b>Results:</b> The mean total blood-absorbed doses by the first, second, third, and fourth methods in the 27 patients were estimated to be 0.46 ± 0.12, 0.45 ± 0.13, 0.46 ± 0.19, and 0.62 ± 0.23 Gy, respectively. The maximum values were 1.40, 0.81, 1.04. and 1.33 Gy, respectively. The difference between the mean values was 37.22%. In the comparison with the total blood-absorbed doses for the patients of other researchers, the difference was 50.77% (difference between the means of 0.65 and 0.32 Gy). <b>Conclusion:</b> None of the total absorbed doses to the blood by the 4 methods in my 27 patients was 2 Gy, the maximum permissible dose. The difference between the total absorbed doses to the blood obtained by different teams of researchers was 50.77%, whereas the difference between the values by the 4 different methods in the 27 patients was 37.22%.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Season of Celebration.","authors":"Kathy S Thomas","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138487809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138487810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SNMMI-TS: 2023 Highlights and a Glimpse into 2024.","authors":"Dmitry D Beyder","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138487811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Report on the PET/CT Image-Based Radiation Dosimetry of [¹⁸F]FDHT in Women, a Validated Imaging Agent with New Applications for Evaluation of Androgen Receptor Status in Women with Metastatic Breast Cancer.","authors":"Keisha C McCall,&nbsp;Mofei Liu,&nbsp;Su-Chun Cheng,&nbsp;Amanda Abbott,&nbsp;Shipra Dubey,&nbsp;Diane Young,&nbsp;Mayzie Johnston,&nbsp;Annick D Van den Abbeele,&nbsp;Beth Overmoyer,&nbsp;Heather Jacene","doi":"10.2967/jnmt.123.265623","DOIUrl":"https://doi.org/10.2967/jnmt.123.265623","url":null,"abstract":"<p><p>In a prospective clinical trial, [¹⁸F]fluoro-5α-dihydrotestosterone ([¹⁸F]FDHT), the radiolabeled analog of the androgen dihydrotestosterone, was used as a PET/CT imaging agent for in vivo assessment of metastatic androgen receptor-positive breast cancer in postmenopausal women. To our knowledge, this article presents the first report of PET/CT image-based radiation dosimetry of [¹⁸F]FDHT in women. <b>Methods:</b> [¹⁸F]FDHT PET/CT imaging was performed on a cohort of 11 women at baseline before the start of therapy and at 2 additional time points during selective androgen receptor modulator (SARM) therapy for androgen receptor-positive breast cancer. Volumes of interest (VOIs) were placed over the whole body and within source organs seen on the PET/CT images, and the time-integrated activity coefficients of [¹⁸F]FDHT were derived. The time-integrated activity coefficients for the urinary bladder were calculated using the dynamic urinary bladder model in OLINDA/EXM software, with biologic half-life for urinary excretion derived from VOI measurements of the whole body in postvoid PET/CT images. The time-integrated activity coefficients for all other organs were calculated from VOI measurements in the organs and the physical half-life of ¹⁸F. Organ dose and effective dose calculations were then performed using MIRDcalc, version 1.1. <b>Results:</b> At baseline before SARM therapy, the effective dose for [¹⁸F]FDHT in women was calculated as 0.020 ± 0.0005 mSv/MBq, and the urinary bladder was the organ at risk, with an average absorbed dose of 0.074 ± 0.011 mGy/MBq. Statistically significant decreases in liver SUV or uptake of [¹⁸F]FDHT were found at the 2 additional time points on SARM therapy (linear mixed model, <i>P</i> < 0.05). Likewise, absorbed dose to the liver also decreased by a small but statistically significant amount at the 2 additional time points (linear mixed model, <i>P</i> < 0.05). Neighboring abdominal organs of the gallbladder wall, stomach, pancreas, and adrenals also showed statistically significant decreases in absorbed dose (linear mixed model, <i>P</i> < 0.05). The urinary bladder wall remained the organ at risk at all time points. Absorbed dose to the urinary bladder wall did not show statistically significant changes from baseline at any of the time points (linear mixed model, <i>P</i> ≥ 0.05). Effective dose also did not show statistically significant changes from baseline (linear mixed model, <i>P</i> ≥ 0.05). <b>Conclusion:</b> Effective dose for [¹⁸F]FDHT in women before SARM therapy was calculated as 0.020 ± 0.0005 mSv/MBq. The urinary bladder wall was the organ at risk, with an absorbed dose of 0.074 ± 0.011 mGy/MBq.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10221836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SNMMI Procedure Standard/EANM Practice Guideline for Palliative Nuclear Medicine Therapies of Bone Metastases.","authors":"Austin R Pantel,&nbsp;Matthias Eiber,&nbsp;Dmitry D Beyder,&nbsp;A Tuba Kendi,&nbsp;Richard Laforest,&nbsp;Isabel Rauscher,&nbsp;Edward B Silberstein,&nbsp;Matthew P Thorpe","doi":"10.2967/jnmt.123.265936","DOIUrl":"10.2967/jnmt.123.265936","url":null,"abstract":"University of Pennsylvania, Department of Radiology; School of Medicine, Department of Nuclear Medicine, Technische Universit€at M€unchen, Munich, Germany; Barnes-Jewish Hospital, Department of Radiology; Mayo Clinic Rochester, Department of Radiology; Washington University, Department of Radiology, St. Louis; Technical University of Munich, Department of Nuclear Medicine; and University of Cincinnati Medical Center, Cincinnati","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Collimators in a High-Resolution, Whole-Body SPECT/CT Device with a Dual-Head Cadmium-Zinc-Telluride Detector for ¹²³I-FP-CIT SPECT.","authors":"Hitoshi Hiraki,&nbsp;Toshimune Ito,&nbsp;Masahisa Onoguchi,&nbsp;Hirotatsu Tsuchikame,&nbsp;Masaaki Shishido,&nbsp;Takafumi Maeno,&nbsp;Takayuki Shibutani,&nbsp;Hiroki Sanada","doi":"10.2967/jnmt.122.265328","DOIUrl":"https://doi.org/10.2967/jnmt.122.265328","url":null,"abstract":"<p><p>The study aim was to evaluate the adaptation of collimators to ¹²³I-<i>N</i>-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl)nortropane (¹²³I-FP-CIT) dopamine transporter SPECT (DAT-SPECT) by a high-resolution whole-body SPECT/CT system with a cadmium-zinc-telluride detector (C-SPECT) in terms of image quality, quantitation, diagnostic performance, and acquisition time. <b>Methods:</b> Using a C-SPECT device equipped with a wide-energy, high-resolution collimator and a medium-energy, high-resolution sensitivity (MEHRS) collimator, we evaluated the image quality and quantification of DAT-SPECT for an anthropomorphic striatal phantom. Ordered-subset expectation maximization iterative reconstruction with resolution recovery, scatter, and attenuation correction was used, and the optimal collimator was determined on the basis of the contrast-to-noise ratio (CNR), percentage contrast, and specific binding ratio. The acquisition time that could be reduced using the optimal collimator was determined. The optimal collimator was used to retrospectively evaluate diagnostic accuracy via receiver-operating-characteristic analysis and specific binding ratios for 41 consecutive patients who underwent DAT-SPECT. <b>Results:</b> When the collimators were compared in the phantom verification, the CNR and percentage contrast were significantly higher for the MEHRS collimator than for the wide-energy high-resolution collimator (<i>P</i> < 0.05). There was no significant difference in the CNR between 30 and 15 min of imaging time using the MEHRS collimator. In the clinical study, the areas under the curve for acquisition times of 30 and 15 min were 0.927 and 0.906, respectively, and the diagnostic accuracies of the DAT-SPECT images did not significantly differ between the 2 times. <b>Conclusion:</b> The MEHRS collimator provided the best results for DAT-SPECT with C-SPECT; shorter acquisition times (<15 min) may be possible with injected activity of 167-186 MBq.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10538243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of the Coronavirus Disease 2019 Pandemic on the Clinical Environment.","authors":"Shannon N Youngblood,&nbsp;Sara L Johnson","doi":"10.2967/jnmt.123.265808","DOIUrl":"https://doi.org/10.2967/jnmt.123.265808","url":null,"abstract":"<p><p>The Nuclear Medicine Technology Certification Board performed an impact survey on the coronavirus disease 2019 pandemic to better assess the current state of nuclear medicine practice within the United States, as well as the perceptions and experiences of technologists working during the pandemic. <b>Methods:</b> A web-based automation platform was used to create, collect, and analyze the survey data. <b>Results:</b> The survey revealed many department protocol variations during the pandemic, a decrease in patient volume, and several other concerns and issues. Experiences regarding staffing and wage changes were varied. <b>Conclusion:</b> This research showed significant inconsistencies in practice and stresses to nuclear medicine technology during the pandemic, as well as concerns for the workforce pipeline. NMTCB decided to delay the JTA process and conduct additional research regarding the workforce.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10159723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Gathering.","authors":"Kathy S Thomas","doi":"10.1142/9789812565846_0003","DOIUrl":"https://doi.org/10.1142/9789812565846_0003","url":null,"abstract":"The Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging in Chicago was fantastic! Gathering with nuclear medicine professionals from around the world to share new ideas, technologies, and information is always an exhilarating experience, and this year was no exception. Although the haze and smoke from the Canadian fires darkened the city skies, nothing could darken the mood of those attending the meeting, either virtually or in person. There was something for everyone, including the festive opening ceremony, the very competitive knowledge bowl, the packed educational opportunities, the many social events, the informative and educational exhibit hall, and the new ‘virtual’ poster hall, not to mention the many networking opportunities! A great social and educational time was had by all! During the educational program, Mary Beth Farrell, JNMT’s CE Editor, presented “How to Write a Manuscript” to students and attending nuclear medicine professionals, designed to provide and encourage future authors with the tools to write successfully. JNMT is always looking for new content and new authors! I followed with a very brief summary of the publication process once the manuscript is submitted. For authors new to the publication process, we stressed the fact that help is available and emphasized that, aside from the prestige and bragging rights of being published, there also may be financial rewards associated with being published! For those not quite ready to put pen to paper, ok, so I’m “old school”—how about fingers to the keyboard—we encouraged becoming a reviewer. Every nuclear medicine professional is an expert in some aspect of nuclear medicine. Why not consider becoming a reviewer of manuscripts specific to that expertise? The process is easy and begins by creating an account on the SNMMI publication portal at JNM Manuscript Processing System (snmjournals.org). Turning to this issue, a diverse collection of continuing education articles is offered. Dual-energy x-ray absorptiometry (DXA) units replaced dual-energy photon absorptiometry (DPA) units in the late 1980s; however, many nuclear medicine departments continue to perform DXA procedures today. Banks et al. present Part 1 of a two-part series that summarizes bone physiology, osteoporosis etiology, and the principles and technical aspects of DXA (1). Part 2 will follow in the December issue with a review of DXA interpretation as well as potential scanning pitfalls and techniques to improve image quality. Practice guidelines support best practice in the clinical setting. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the European Association of Nuclear Medicine (EANM) routinely review and update guidelines for imaging and therapeutic nuclear medicine procedures to improve the quality of service for patients worldwide. The updated practice guideline for the treatment of palliation of bone pain provides the latest information on the therapeutic use of available ","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1142/9789812565846_0003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45834169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}