{"title":"Recognizing and Responding to the Acute Cardiac Stress Patient.","authors":"Geoffrey Currie, Hosen Kiat","doi":"10.2967/jnmt.125.269450","DOIUrl":"10.2967/jnmt.125.269450","url":null,"abstract":"<p><p>A cardiac emergency in SPECT/CT and PET/CT occurs infrequently but necessitates prompt recognition and an appropriate response. The emergence of <sup>18</sup>F-based myocardial perfusion radiopharmaceuticals is anticipated to increase the use of cardiac stress testing; therefore, it is crucial for personnel, including nuclear medicine technologists in PET departments, to be equipped with proper training and competency to identify and manage deteriorating cardiac patients or emergency cardiac events. This article provides insight into the foundation principles of both cardiac stress testing and the use of adjunctive medications to manage patients after stress. The acute deteriorating nuclear cardiology patient is outlined, including recognizing crucial changes in vital signs and basic electrocardiogram interpretation. Key medications associated with an emergency response are detailed. Armed with these tools, nuclear medicine technologists can more confidently care for high-risk nuclear cardiology patients.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"116-122"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren
{"title":"Gender and Ethnicity Bias of Text-to-Image Generative Artificial Intelligence in Medical Imaging, Part 2: Analysis of DALL-E 3.","authors":"Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Eric Rohren","doi":"10.2967/jnmt.124.268359","DOIUrl":"10.2967/jnmt.124.268359","url":null,"abstract":"<p><p>Disparity among gender and ethnicity remains an issue across medicine and health science. Only 26%-35% of trainee radiologists are female, despite more than 50% of medical students' being female. Similar gender disparities are evident across the medical imaging professions. Generative artificial intelligence text-to-image production could reinforce or amplify gender biases. <b>Methods:</b> In March 2024, DALL-E 3 was utilized via GPT-4 to generate a series of individual and group images of medical imaging professionals: radiologist, nuclear medicine physician, radiographer, nuclear medicine technologist, medical physicist, radiopharmacist, and medical imaging nurse. Multiple iterations of images were generated using a variety of prompts. Collectively, 120 images were produced for evaluation of 524 characters. All images were independently analyzed by 3 expert reviewers from medical imaging professions for apparent gender and skin tone. <b>Results:</b> Collectively (individual and group images), 57.4% (<i>n</i> = 301) of medical imaging professionals were depicted as male, 42.4% (<i>n</i> = 222) as female, and 91.2% (<i>n</i> = 478) as having a light skin tone. The male gender representation was 65% for radiologists, 62% for nuclear medicine physicians, 52% for radiographers, 56% for nuclear medicine technologists, 62% for medical physicists, 53% for radiopharmacists, and 26% for medical imaging nurses. For all professions, this overrepresents men compared with women. There was no representation of persons with a disability. <b>Conclusion:</b> This evaluation reveals a significant overrepresentation of the male gender associated with generative artificial intelligence text-to-image production using DALL-E 3 across the medical imaging professions. Generated images have a disproportionately high representation of white men, which is not representative of the diversity of the medical imaging professions.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"162-168"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Technegas Ventilation Lung Imaging in the United States.","authors":"Kathy S Thomas, Tina M Buehner","doi":"10.2967/jnmt.125.269774","DOIUrl":"10.2967/jnmt.125.269774","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"180-182"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PET/CT Case Series: Unmasking the Mystery of Cardiac Sarcoidosis.","authors":"Diane K Soulek","doi":"10.2967/jnmt.125.269732","DOIUrl":"10.2967/jnmt.125.269732","url":null,"abstract":"<p><p>The annual incidence of cardiac sarcoidosis is low, but increased awareness of this inflammatory condition has led to earlier disease recognition. High mortality rates compel prompt diagnosis and intervention to reduce the risk of major adverse cardiac events. This cardiac sarcoid PET/CT case series provides information on cardiac sarcoid features, reviews advanced imaging and its role in treatment monitoring, examines the importance of dietary modifications required for <sup>18</sup>F-FDG cardiac sarcoid imaging and the associated consequences of noncompliant patient preparation, and provides an in-depth review of a patient's cardiac sarcoid journey.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"104-112"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Advances in Nuclear Cardiology-2025.","authors":"Mary Beth Farrell","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":"53 2","pages":"89"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Liu, Lionel T Munemo, Nuno Martins, Vasileios Kouranos, Athol U Wells, Rakesh K Sharma, Kshama Wechalekar
{"title":"Assessment of Cardiac Sarcoidosis with PET/CT.","authors":"Alexander Liu, Lionel T Munemo, Nuno Martins, Vasileios Kouranos, Athol U Wells, Rakesh K Sharma, Kshama Wechalekar","doi":"10.2967/jnmt.124.268142","DOIUrl":"10.2967/jnmt.124.268142","url":null,"abstract":"<p><p><sup>18</sup>F-FDG PET with CT is an important advanced imaging modality used to assess patients with suspected or known cardiac sarcoidosis (CS). <sup>18</sup>F-FDG PET is indicated for CS work-up in patients with extra-CS and abnormal screening results for cardiac involvement, patients under 60 y old presenting with unexplained high-grade atrioventricular heart block, and patients with suspected CS and idiopathic ventricular arrhythmias. In patients with established CS, serial <sup>18</sup>F-FDG PET can be used to assess response to immunosuppressive therapy and long-term surveillance for reactivation of myocardial inflammation in patients with low-grade or quiescent disease. Patient preparation before <sup>18</sup>F-FDG PET scanning is key in ensuring adequate suppression of physiologic myocardial <sup>18</sup>F-FDG uptake, to maximize the power of the test to detect pathology. Inadequate dietary preparation can cause diffuse or focal-on-diffuse <sup>18</sup>F-FDG uptake in the absence of active inflammation. It is important to assess resting myocardial perfusion, typically with <sup>82</sup>Rb cardiac PET. Several different patterns of abnormalities have been reported in patients with CS, including normal myocardial perfusion with focal or patchy <sup>18</sup>F-FDG uptake suggesting myocardial inflammation without scarring; the presence of a myocardial perfusion defect with abnormal <sup>18</sup>F-FDG uptake suggesting myocardial scarring with inflammation; and the presence of a myocardial perfusion defect without <sup>18</sup>F-FDG uptake indicating myocardial scarring without inflammation. Prognostically, the presence of myocardial perfusion defects and abnormal <sup>18</sup>F-FDG uptake has been shown to be an independent predictor of death or ventricular arrythmias. A high myocardial SUV<sub>max</sub> in the left and right ventricles has been shown to be an independent predictor of adverse clinical outcomes. Although the diagnostic performance of <sup>18</sup>F-FDG PET has been studied, the reference standard for CS tended to rely on clinical criteria, which may be less sensitive than <sup>18</sup>F-FDG PET at detecting CS. Therefore, the diagnosis of CS should rely on a multidisciplinary team approach involving multimodality advanced imaging, including echocardiography, cardiovascular MR, and <sup>18</sup>F-FDG PET.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"123-129"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-Sensitivity Troponin Elevation in a Young Woman with Typical Chest Pain: The Heart of the Matter.","authors":"Rahul Annabathula, Wengen Chen, Scott Jerome","doi":"10.2967/jnmt.125.269733","DOIUrl":"10.2967/jnmt.125.269733","url":null,"abstract":"<p><p>In the era of high-sensitivity troponin, minor elevations are often attributed to noncardiac etiologies. However, in patients who present with characteristic symptoms, any troponin elevation is concerning. We detail a case of a 37-y-old woman who presented to an outside hospital with typical chest pain and had a mild elevation in high-sensitivity troponin. Given her overall stability, she was discharged with outpatient cardiology follow-up. <sup>82</sup>Rb PET/CT myocardial perfusion imaging test demonstrated a large, reversible anteroseptal perfusion defect. Coronary angiography revealed severe (80%) stenosis in the proximal left anterior descending artery treated with a single stent. This case highlights the need to have a high index of suspicion in young people with minor troponin elevations and pursue timely imaging.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"169-171"},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hinna Shahid, Lois Miller, Obaid Kazmi, Peter Seidensticker
{"title":"Delivery Methods of Radiopharmaceuticals: Exploring Global Strategies to Minimize Occupational Radiation Exposure.","authors":"Hinna Shahid, Lois Miller, Obaid Kazmi, Peter Seidensticker","doi":"10.2967/jnmt.124.268043","DOIUrl":"10.2967/jnmt.124.268043","url":null,"abstract":"<p><p>In the world of nuclear medicine, health care professionals face the challenge of safeguarding themselves and their patients from occupational radiation exposure. As the field experiences exponential growth, driven by the surge in approvals of radiopharmaceuticals for diagnostic and therapeutic applications, it becomes vital to delve into the delivery methods of radiopharmaceuticals. Health care professionals take precautions during radiopharmaceutical administration, including maintaining distance from radioactive sources, using shielding, limiting exposure time, and monitoring radiation levels with badges. Regular evaluations provide compliance with recommended exposure limits, yet concerns persist, especially regarding the cumulative radiation exposure from manual injections over time. Understanding the long-term effects of radiation exposure has spurred the development of cutting-edge medical device technologies, such as autoinjectors, designed to administer radiopharmaceuticals accurately while minimizing total radiation dose to health care professionals. The U.S. Pharmacopeia 825 regulation refers to these devices as \"direct infusion systems.\" Nuclear medicine technologists commonly refer to them as \"autoinjectors,\" whereas device manufacturers may use terms such as injection system, radiopharmaceutical injector, or infusion system. Despite variations in terminology, these devices hold a pivotal role in shaping the future of radiopharmaceutical delivery. In an era of escalating demand for PET procedures worldwide, skilled health care professionals ensure the safe and precise dosing of radiopharmaceuticals. This article explores the state-of-the-art medical devices in radiopharmaceutical delivery, spotlighting transformative medical devices currently revolutionizing the nuclear medicine landscape in the global market.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"2-6"},"PeriodicalIF":1.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hung Q Dam, David C Brandon, Crystal G Gantz, Vesper V Grantham, Chen S Low, Harry W Schroeder, Michael G Stabin, Lionel S Zuckier
{"title":"The SNMMI Procedure Standard/ACNM Practice Guideline for Gastrointestinal Bleeding Scintigraphy 3.0.","authors":"Hung Q Dam, David C Brandon, Crystal G Gantz, Vesper V Grantham, Chen S Low, Harry W Schroeder, Michael G Stabin, Lionel S Zuckier","doi":"10.2967/jnmt.124.269004","DOIUrl":"10.2967/jnmt.124.269004","url":null,"abstract":"","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"14-23"},"PeriodicalIF":1.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Hosen Kiat, Eric Rohren
{"title":"Fitness for Purpose of Text-to-Image Generative Artificial Intelligence Image Creation in Medical Imaging.","authors":"Geoffrey Currie, Johnathan Hewis, Elizabeth Hawk, Hosen Kiat, Eric Rohren","doi":"10.2967/jnmt.124.268402","DOIUrl":"10.2967/jnmt.124.268402","url":null,"abstract":"<p><p>The recent emergence of text-to-image generative artificial intelligence (AI) diffusion models such as DALL-E, Firefly, Stable Diffusion, and Midjourney has been touted with popular hype about the transformative potential in health care. This hype-driven, rapid assimilation comes with few professional guidelines and without regulatory oversight. Despite documented limitations, text-to-image generative AI creations have permeated nuclear medicine and medical imaging. Given the representation of medical imaging professions and potential dangers in misrepresentation and errors from both a reputation and community harm perspective, critical quality assurance of text-to-image generative AI creations is required. Here, tools for evaluating the quality and fitness for purpose of generative AI images in nuclear medicine and imaging are discussed. Generative AI text-to-image creation suffers quality limitations that are generally prohibitive of mainstream use in nuclear medicine and medical imaging. Text-to-image generative AI diffusion models should be used within a framework of critical quality assurance for quality and accuracy.</p>","PeriodicalId":16548,"journal":{"name":"Journal of nuclear medicine technology","volume":" ","pages":"63-67"},"PeriodicalIF":1.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}