Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand.

IF 1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich
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Abstract

Diagnostic reference levels (DRLs) are an important tool for controlling radiation exposure and ensuring safety in medical applications. In Thailand, DRL data have been gathered and established for nuclear medicine diagnostics since 2021. However, there is a lack of information on PET imaging examinations. At the National Cyclotron and PET Scan Centre, Chulabhorn Hospital, radiopharmaceuticals are produced for medical imaging and research, and a wide range of PET/CT and PET/MRI examinations are performed. Our objective was to investigate the administered activity of radiopharmaceuticals in patients undergoing PET imaging, especially the existing data on DRLs in medical diagnostic imaging. Methods: This was a retrospective study on nuclear medicine patients at the National Cyclotron and PET Scan Centre in 2023. Statistical analysis, including the mean and the 75th percentile values, was conducted to determine DRLs according to the International Commission on Radiological Protection guidelines. Results: The center performed 8,711 PET/CT and PET/MRI studies with 13 protocols in 2023. The most commonly administered activity was 18F-FDG in oncology and neurology examinations, with DRLs of 186.11 and 136.16 MBq, respectively. These values were notably almost twice lower than several reports in other countries. Conclusion: There is a lack of comprehensive data on most DRLs for PET imaging at this center because of the nonwidespread use of several radiopharmaceuticals. However, the lower DRLs for 18F-FDG can highlight the need for ongoing investigation toward the establishment of local DRLs, as well as assurance on the safety and efficiency of radiation used in nuclear medicine.

泰国 Chulabhorn 医院 PET 成像诊断参考水平。
诊断参考水平(DRL)是控制辐照和确保医疗应用安全的重要工具。在泰国,自 2021 年起就开始收集和建立核医学诊断参考水平数据。然而,目前还缺乏 PET 成像检查方面的信息。朱拉蓬医院的国家回旋加速器和正电子发射计算机断层扫描中心生产用于医学成像和研究的放射性药物,并进行各种正电子发射计算机断层扫描(PET)/计算机断层扫描(CT)和正电子发射计算机断层扫描(PET)/计算机磁共振成像(MRI)检查。我们的目的是调查接受 PET 成像检查的患者体内放射性药物的给药活性,特别是医疗诊断成像中 DRL 的现有数据。研究方法这是一项回顾性研究,研究对象是 2023 年在国家回旋加速器和 PET 扫描中心接受治疗的核医学患者。根据国际辐射防护委员会的指导方针,对包括平均值和第 75 百分位值在内的数据进行了统计分析,以确定 DRL。结果:该中心在 2023 年进行了 8,711 次 PET/CT 和 PET/MRI 研究,共有 13 个方案。在肿瘤学和神经学检查中,最常使用的活性是 18F-FDG,其 DRL 分别为 186.11 和 136.16 MBq。这些数值明显比其他国家的一些报告低了近一倍。结论由于本中心未广泛使用多种放射性药物,因此缺乏有关 PET 成像大多数 DRL 的全面数据。不过,18F-FDG 的 DRL 值较低,这说明有必要继续调查,以确定当地的 DRL 值,并确保核医学所用辐射的安全性和效率。
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来源期刊
Journal of nuclear medicine technology
Journal of nuclear medicine technology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.90
自引率
15.40%
发文量
57
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