Journal of neurosurgical sciences最新文献

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Human placenta in vascular neurosurgery training: a comprehensive review of laboratory models, possible exercises, and assessments for skills improvement. 血管神经外科训练中的人胎盘:实验室模型的全面回顾,可能的练习,以及技能改进的评估。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-12-01 DOI: 10.23736/S0390-5616.24.06303-3
Francesco Restelli, Elio Mazzapicchi, Jacopo Falco, Morgan Broggi, Ignazio G Vetrano, Paolo Ferroli, Francesco Acerbi
{"title":"Human placenta in vascular neurosurgery training: a comprehensive review of laboratory models, possible exercises, and assessments for skills improvement.","authors":"Francesco Restelli, Elio Mazzapicchi, Jacopo Falco, Morgan Broggi, Ignazio G Vetrano, Paolo Ferroli, Francesco Acerbi","doi":"10.23736/S0390-5616.24.06303-3","DOIUrl":"10.23736/S0390-5616.24.06303-3","url":null,"abstract":"<p><strong>Introduction: </strong>Simulation is increasingly recognized as an important tool to enhance neurosurgical education. In this field, especially in neurovascular surgery, human placenta (hPl) is being recognized as a valuable training model because of its abundant availability, ethical acceptance, and analogous vasculature with other vessels of the human body. Nevertheless, although a rising body of literature is witnessing a renovated interest toward this \"old\" model, to date no comprehensive reviews on the topics are available. Main objective of this paper is to comprehensively review hPl use in neurovascular surgery training, focusing on model preparation, type of possible exercises along with assessment tools which can be used to check for trainees learning.</p><p><strong>Evidence acquisition: </strong>A systematic review of the pertinent literature was performed, following PRISMA guidelines, searching the following key words in \"title/abstract\" fields in only English-written works: \"placenta and neurosurgery.\" We focused on preclinical works concerning use of hPl models in neurovascular surgery training. We included studies published in the last 40 years, till December 31<sup>st</sup>, 2023.</p><p><strong>Evidence synthesis: </strong>A total of 950 scientific publications were initially screened, and 23 papers met the inclusion and exclusion criteria. In summary, the chorionic surface of hPl may be used as a neurovascular gym where different exercises can be performed. Placenta models can be produced with or without the use of intravascular dyes and or/pumping systems to resemble a beating-heart vascular system. The three main neurovascular surgical fields where hPl is being considered to be highly simulative are: 1) Sylvian fissure dissection; 2) aneurysm dissection and clipping; 3) bypass training. Considering the simulative purpose, face, content and construct validify of hPl model have been tested and verified by many authors, although still few data are available regarding transfer/predictive validity.</p><p><strong>Conclusions: </strong>This systematic review highlighted the easiness of preparation and availability along with the strong didactical meaning that the use of hPl-based models may have in the field of neurovascular surgery training. In view of current progressive lowering of surgical vascular cases and increasing technical demand related to their management, further studies aimed to assess if this simulator could be able to produce a learning effect and improve performance with continued use are strongly needed.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":"68 6","pages":"646-659"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cracking the glass ceiling: women's evolution in neurosurgical leadership. 打破玻璃天花板:女性在神经外科领导岗位上的发展。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-12-01 Epub Date: 2024-07-04 DOI: 10.23736/S0390-5616.24.06289-1
Teresa Somma, Ilaria Bove, Francesca Vitulli, Felice Esposito, Tamara Ius, Paolo Cappabianca
{"title":"Cracking the glass ceiling: women's evolution in neurosurgical leadership.","authors":"Teresa Somma, Ilaria Bove, Francesca Vitulli, Felice Esposito, Tamara Ius, Paolo Cappabianca","doi":"10.23736/S0390-5616.24.06289-1","DOIUrl":"10.23736/S0390-5616.24.06289-1","url":null,"abstract":"","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"643-645"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of surgical set-up of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics. 内镜下二外科四手前颅底手术的手术设置对外科医生工效学的影响。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-12-01 Epub Date: 2023-05-09 DOI: 10.23736/S0390-5616.23.05991-X
Pavithran Maniam, James Lucocq, Rohit Gohil, Ashok Rokade
{"title":"The impact of surgical set-up of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics.","authors":"Pavithran Maniam, James Lucocq, Rohit Gohil, Ashok Rokade","doi":"10.23736/S0390-5616.23.05991-X","DOIUrl":"10.23736/S0390-5616.23.05991-X","url":null,"abstract":"<p><strong>Background: </strong>The impact of different surgical set-ups of endoscopic two surgeon four hand anterior skull base surgeries on surgeons' ergonomics remain unclear. This study aims to explore the effect of surgeon, patient and surgical screen positioning on surgeons' ergonomics using the Rapid Entire Body Assessment (REBA) tool.</p><p><strong>Methods: </strong>A total of 20 different surgical positions of anterior skull base surgery were simulated and the ergonomic impact on surgeons' neck, truck, leg and wrist were measured using the validated Rapid Entire Body Assessment (REBA) tool. To investigate the ergonomic effect of different surgical setups, the operating surgeon, assisting surgeon, patient head, camera and screen positions were positioned differently in each surgical position.</p><p><strong>Results: </strong>The lowest REBA Score recorded is 3 whereas the highest score is 8. The REBA scores for the majority of positions are 3 highlighting that these positions are ergonomically favorable. Position 12 is the least ergonomically favorable position with a total REBA score of 19. In this position, operating surgeon is positioned to the right of the patient, assisting surgeon to the left of patient, patient head in central position with camera held by operating surgeon and one screen is placed to the right of patient. Positions 13 and 17 are the most ergonomically favorable positions with a total REBA score of 12. In these positions, the patient's head is positioned to the center, two screens were utilized, and the surgeons were positioned on either side of the patient. The utilization of 2 screens with a central patient head position with the surgeons placed on either side of the patient contribute towards a more ergonomically state in these positions.</p><p><strong>Conclusions: </strong>Certain positional behaviors are better at reducing musculoskeletal injury risk when compared to other. Positions with two screens and central head positions are more favourable ergonomically and surgeons should consider this set-up to reduce musculoskeletal injuries during anterior skull base surgery.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"691-697"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9432924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The "banana splitting DREZotomy": an atraumatic method to improve pain relief after dorsal root entry zone lesioning in brachial plexus injuries. Case series and tenets for the treatment. “香蕉劈开式DREZotomy”:一种改善臂丛神经损伤后背根进入区损伤后疼痛缓解的无创性方法。病例系列和治疗原则。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-12-01 Epub Date: 2023-05-18 DOI: 10.23736/S0390-5616.23.06018-6
Stefano Ferraresi, Lorenzo Maistrello, Elisabetta Basso, Piero DI Pasquale
{"title":"The \"banana splitting DREZotomy\": an atraumatic method to improve pain relief after dorsal root entry zone lesioning in brachial plexus injuries. Case series and tenets for the treatment.","authors":"Stefano Ferraresi, Lorenzo Maistrello, Elisabetta Basso, Piero DI Pasquale","doi":"10.23736/S0390-5616.23.06018-6","DOIUrl":"10.23736/S0390-5616.23.06018-6","url":null,"abstract":"<p><strong>Background: </strong>The treatment of neuropathic deafferentation pain due to avulsion injuries of the brachial plexus is a major problem, albeit rare, in the neurosurgical practice. The aim of the paper is to present step-by-step the main principles of a surgical upgrade of the well-known Dorsal Root Entry Zone lesioning, that we named banana splitting DREZotomy.</p><p><strong>Methods: </strong>A comparison is made among three groups of patients, two of which were treated following the classic techniques, while in the third no physical agent is applied to the spinal cord during surgery.</p><p><strong>Results: </strong>The patients operated on following the well-established surgical procedures showed a short-term success rate around 70%, online with the data of the ongoing literature. The results with the banana-splitting technique, instead, have been astonishing both in terms of resolution of pain, absence of true complications and of unpleasant side effects.</p><p><strong>Conclusions: </strong>A purely dissective technical variant of the surgical procedure called DREZ lesioning has shown better results overcoming the 30% failures of all the reported series. The profound and permanent splitting of the posterior horn and the absence of any other component (heat propagation, radiofrequency, or dotted coagulation) are the major factors which may explain such outstanding results.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"704-713"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9833890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family-base rare variant association analysis in Saudi Arabian hydrocephalus subjects using whole exome sequencing. 利用全外显子组测序分析沙特阿拉伯脑积水患者的家族基础罕见变异关联。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-12-01 Epub Date: 2023-05-09 DOI: 10.23736/S0390-5616.23.06010-1
Ahmed Ammar, Dalal K Bubshait, Abdulrazaq Al Ojan, Shuroq A Alshari, Cyril Cyrus, Rawan Alanazi, Mohammed A Al Ghamdi, Brendan J Keating, Abdulrahman Al-Anazi, Noorah H Al Qahtani, Amein K Al-Ali
{"title":"Family-base rare variant association analysis in Saudi Arabian hydrocephalus subjects using whole exome sequencing.","authors":"Ahmed Ammar, Dalal K Bubshait, Abdulrazaq Al Ojan, Shuroq A Alshari, Cyril Cyrus, Rawan Alanazi, Mohammed A Al Ghamdi, Brendan J Keating, Abdulrahman Al-Anazi, Noorah H Al Qahtani, Amein K Al-Ali","doi":"10.23736/S0390-5616.23.06010-1","DOIUrl":"10.23736/S0390-5616.23.06010-1","url":null,"abstract":"<p><strong>Background: </strong>Hydrocephalus is a highly heterogeneous multifactorial disease that arises from genetic and environmental factors. Familial genetic studies of hydrocephalus have elucidated four robustly associated hydrocephalus associated loci. This study aims to identify potential genetic causation in cases of hydrocephalus, with or without spina bifida and Dandy Walker Syndrome (DWS), using family-based rare variant association analysis of whole exome sequencing.</p><p><strong>Methods: </strong>We performed whole exome sequencing in 143 individuals across 48 families where at least one offspring was affected with hydrocephalus (N.=27), with hydrocephalus with spina bifida (N.=21) and with DWS (N.=3), using Illumina HiSeq 2500 instrument.</p><p><strong>Results: </strong>No pathogenic or putative pathogenic single-nucleotide variants were evident in the four known hydrocephalus loci in our subjects. However, after examining 73 known hydrocephalus genes previously identified from literature, we identified three potentially impactful variants from the cohort. Using a gene panel comprising variants in known neural tube defects loci, we identified a total of 1024 potentially deleterious variants, of which 797 were missense variants and 191 were frameshift variants, 36 were stop gain/loss variants. A small portion of our family pedigree analyses yielded putative genetic signals which may be responsible for hydrocephaly elated phenotypes, however the low diagnostic yield may be due to lack of capture of genetic variants in the exonic regions i.e. structural variants may only be evident from whole genome sequencing.</p><p><strong>Conclusions: </strong>We identified three potentially impactful variants from our cohort in 73 known hydrocephalus genes previously identified in literature.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"698-703"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9432927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of intra-operative skull fixation techniques on cervical sagittal parameters. 术中颅骨固定技术对颈椎矢状面参数的影响比较。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-11-19 DOI: 10.23736/S0390-5616.24.06255-6
Connor C Jacob, Ryan G Eaton, Andrew J Grossbach, Asad Akhter, Nathaniel Toop, Joshua Wang, Joravar Dhaliwal, Stephanus V Viljoen
{"title":"Comparison of intra-operative skull fixation techniques on cervical sagittal parameters.","authors":"Connor C Jacob, Ryan G Eaton, Andrew J Grossbach, Asad Akhter, Nathaniel Toop, Joshua Wang, Joravar Dhaliwal, Stephanus V Viljoen","doi":"10.23736/S0390-5616.24.06255-6","DOIUrl":"10.23736/S0390-5616.24.06255-6","url":null,"abstract":"<p><strong>Background: </strong>There is limited literature concerning the use of bi-vector traction to a Mayfield following posterior cervical fusion with respect to cervical alignment parameters. The objective of this study was to determine how variability of intra-operative fixation methods for posterior cervical fusion affects post-operative cervical sagittal alignment parameters.</p><p><strong>Methods: </strong>After institutional review board (IRB) approval, retrospective chart review of a total of 54 patients who underwent posterior cervical fusion from July 2017 to December 2019 was conducted. The patients were divided into two cohorts based on their intra-operative positioning, those who were affixed to a three-point fixation system, and those who were placed in bi-vector traction. Pre- and post-operative cervical alignment parameters were measured.</p><p><strong>Results: </strong>There was no difference in post-operative sagittal parameters between the two groups. Each group showed a statistically significant difference in T1-slope when comparing pre- and post-operative measurements.</p><p><strong>Conclusions: </strong>In our study we did not find that any of our techniques including bi-vector traction, static Mayfield positioning, or dynamic Mayfield positioning were very effective in adding lordosis during posterior cervical fusion surgeries. Interestingly, we also found a statistically significant increase in T1 slope and resulting trend towards increased cervical SVA.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follow-up neuroimaging after non-perimesencephalic, angiogram-negative subarachnoid hemorrhage. 非脑周血管造影阴性蛛网膜下腔出血后的后续神经影像学检查。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2023-01-31 DOI: 10.23736/S0390-5616.22.05686-7
Jean-Philippe Dufour, Menno R Germans, Emanuela Keller, Zsolt Kulcsàr, Luca Regli, Giuseppe Esposito
{"title":"Follow-up neuroimaging after non-perimesencephalic, angiogram-negative subarachnoid hemorrhage.","authors":"Jean-Philippe Dufour, Menno R Germans, Emanuela Keller, Zsolt Kulcsàr, Luca Regli, Giuseppe Esposito","doi":"10.23736/S0390-5616.22.05686-7","DOIUrl":"10.23736/S0390-5616.22.05686-7","url":null,"abstract":"<p><strong>Background: </strong>In approximately 15% of spontaneous subarachnoid hemorrhage (SAH) patients, no bleeding source is found in the initial imaging. These patients can be categorized as either perimesencephalic (PM-SAH) or non-perimesencephalic (NP-SAH) subarachnoid hemorrhage patients. Follow-up imaging is routinely performed after NP-SAH to detect treatable etiologies; however, the optimal follow-up imaging protocol remains unclear. This study examines the optimal time interval to re-imaging and the performance of magnetic resonance imaging and angiography (MRI/A) in this setting.</p><p><strong>Methods: </strong>In this retrospective study, the records of NP-SAH patients treated at the University Hospital of Zurich (Switzerland) from 2005 to 2018 were analyzed. Clinical and radiological data were collected. Re-imaging data was grouped according to imaging modality and divided into three time-categories after bleeding: short-term (<2 weeks), medium-term (2-8 weeks) and long-term (>8 weeks) re-imaging.</p><p><strong>Results: </strong>Eighty-one NP-SAH patients were included. In 8 patients an aneurysm was diagnosed during re-imaging via digital subtraction angiography (9.9% diagnostic yield). Five aneurysms were detected at short-term in 81 patients (6.2% short-term yield) and three at medium-term re-imaging in 27 patients (11.1% medium-term yield). No aneurysms were found after 8 weeks in 56 patients. Five of these 8 patients also received MRI/A re-imaging, which was able to show the aneurysm in all 5 cases.</p><p><strong>Conclusions: </strong>Our study emphasizes the importance of re-imaging in NP-SAH patients, which should be done both at short-term and at medium-term follow-up after the hemorrhage. Long-term re-imaging after 8 weeks might not be of diagnostic benefit. MRI/A might be considered as a possible noninvasive re-imaging modality in this setting.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"541-550"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9152205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive value of neutrophil-to-lymphocyte ratio and neutrophil-to-monocyte ratio in severe traumatic brain injury: a retrospective cohort. 中性粒细胞与淋巴细胞比率和中性粒细胞与单核细胞比率在严重脑外伤中的预测价值:回顾性队列。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2023-03-08 DOI: 10.23736/S0390-5616.23.05877-0
Luiz F Matias, Murilo D Pimentel, Mateus F Medeiros, Franciani R Rocha, Marcelo V Gambetta, Samantha C Lopes
{"title":"Predictive value of neutrophil-to-lymphocyte ratio and neutrophil-to-monocyte ratio in severe traumatic brain injury: a retrospective cohort.","authors":"Luiz F Matias, Murilo D Pimentel, Mateus F Medeiros, Franciani R Rocha, Marcelo V Gambetta, Samantha C Lopes","doi":"10.23736/S0390-5616.23.05877-0","DOIUrl":"10.23736/S0390-5616.23.05877-0","url":null,"abstract":"<p><strong>Background: </strong>The neutrophil-lymphocyte ratio (NLR), the platelet-lymphocyte ratio (PLR), the lymphocyte-monocyte ratio (LMR), the neutrophil-monocyte ratio (NMR) and the systemic immune inflammation index (SII) are associated with clinical outcomes in oncological diseases, cardiovascular diseases, infectious / inflammatory diseases, endocrinological, pulmonary and brain injuries. Here, we investigate its association with hospital mortality in patients with severe traumatic brain injury.</p><p><strong>Methods: </strong>We retrospectively reviewed clinical data from patients with severe traumatic brain injury (sTBI) who were treated in our department between January 2015 and December 2020. NLR, PLR, NMR, LMR and SII data were collected between admission and day 3, as well as other indicators related. The relationship between hematological ratios and in-hospital mortality were analyzed.</p><p><strong>Results: </strong>A total of 96 patients were included in study, hospital mortality was 40.6% (N.=39). The levels of NLR on admission (D0), NLR day 1 (D1), NLR day 2 (D2), NLR day 3 (D3), NMR day 1 (D1) and NMR day (2) remained significantly higher in patients with death intra-hospital (P=0.030; P=0.038; P=0.016; P=0.048; P=0.046 and P=0.001, respectively). Multivariate logistic analysis showed that higher NLR values at admission and day 2 NMR were associated with in-hospital mortality (OR=1.120, P=0.037; and OR=1.307, P=0.004, respectively). Analysis of the recipient operating characteristic (ROC) curve showed that the NLR on admission had a sensitivity of 59.0% and a specificity of 66.7% (area under the curve 0.630, P=0.031, Youden's Index 0.26) and the NMR of day 2 had a sensitivity of 67.7% and a specificity of 70.4% (area under the curve 0.719, P=0.001, Youden's index 0.38) to predict mortality intra-hospital based on the best threshold.</p><p><strong>Conclusions: </strong>Our analysis indicates that higher NLR levels on admission and day 2 NMR are independent predictors of in-hospital mortality in patients with sTBI.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"604-611"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10867134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of baseline frailty and age with postoperative outcomes in metastatic brain tumor patients. 转移性脑肿瘤患者的基线虚弱程度和年龄与术后效果的关系。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-11-07 DOI: 10.23736/S0390-5616.22.05865-9
Christine J Colasacco, Joanna Abouezzi, Sophia Arbuiso, Derek B Asserson, Syed F Kazim, Kyril L Cole, Alis J Dicpinigaitis, Jose Dominguez, Rohini G McKEE, Meic H Schmidt, William T Couldwell, Christian A Bowers
{"title":"Association of baseline frailty and age with postoperative outcomes in metastatic brain tumor patients.","authors":"Christine J Colasacco, Joanna Abouezzi, Sophia Arbuiso, Derek B Asserson, Syed F Kazim, Kyril L Cole, Alis J Dicpinigaitis, Jose Dominguez, Rohini G McKEE, Meic H Schmidt, William T Couldwell, Christian A Bowers","doi":"10.23736/S0390-5616.22.05865-9","DOIUrl":"10.23736/S0390-5616.22.05865-9","url":null,"abstract":"<p><strong>Background: </strong>The impact of baseline frailty status versus that of chronological age on surgical outcomes of metastatic brain tumor patients remains largely unknown. The present study aimed to evaluate this relationship for preoperative risk stratification using a large national database.</p><p><strong>Methods: </strong>The National Surgical Quality Improvement Program database was queried to extract data of metastatic brain tumor patients who underwent surgery between 2015 and 2019 (N.=5943). Univariate and multivariate analyses were performed to assess the effect of age and modified Frailty Index-5 on mortality, major complications, unplanned readmission and reoperation, extended length of stay (eLOS), and non-home discharge.</p><p><strong>Results: </strong>Both univariate and multivariate analyses demonstrated that frailty status was significantly predictive of 30-day mortality, major complications, eLOS, and non-home discharge. Although increasing age was also a significant predictor of eLOS and discharge to non-home destination, effect sizes were smaller compared with frailty.</p><p><strong>Conclusions: </strong>The present study, based on analysis of data from a large national registry, shows that frailty, when compared with age, is a superior predictor of postoperative outcomes in metastatic brain tumor patients. A future prospective study, namely a randomized controlled trial, would be beneficial in helping to corroborate the findings of this retrospective study.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"526-532"},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10444368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculum sellae meningiomas: surgical outcomes in 65 patients, review of the literature and proposal for an anatomical and radiological classification. 蝶鞍管脑膜瘤:65 例患者的手术结果、文献综述以及解剖学和放射学分类建议。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2023-06-12 DOI: 10.23736/S0390-5616.23.06061-7
Giulio Maira, Biagia LA Pira, Alessandra Serraino, Maria P Tropeano, Delia Cannizzaro
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