Journal of neurosurgical sciences最新文献

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Roxadustat protects oxidative stress and tissue injury in the brain induced by ischemic stroke via the HIF-1α/NRF2 axis. 罗沙司他通过HIF-1α/NRF2轴保护缺血性中风引起的脑氧化应激和组织损伤。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-28 DOI: 10.23736/S0390-5616.24.06329-X
Keping Jiao, Huiqin Zhang, Bin Li, Yanyan Wang, Jian Liu
{"title":"Roxadustat protects oxidative stress and tissue injury in the brain induced by ischemic stroke via the HIF-1α/NRF2 axis.","authors":"Keping Jiao, Huiqin Zhang, Bin Li, Yanyan Wang, Jian Liu","doi":"10.23736/S0390-5616.24.06329-X","DOIUrl":"https://doi.org/10.23736/S0390-5616.24.06329-X","url":null,"abstract":"","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Follow-up neuroimaging after non-perimesencephalic, angiogram-negative subarachnoid hemorrhage. 非脑周血管造影阴性蛛网膜下腔出血后的后续神经影像学检查。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2023-01-31 DOI: 10.23736/S0390-5616.22.05686-7
Jean-Philippe Dufour, Menno R Germans, Emanuela Keller, Zsolt Kulcsàr, Luca Regli, Giuseppe Esposito
{"title":"Follow-up neuroimaging after non-perimesencephalic, angiogram-negative subarachnoid hemorrhage.","authors":"Jean-Philippe Dufour, Menno R Germans, Emanuela Keller, Zsolt Kulcsàr, Luca Regli, Giuseppe Esposito","doi":"10.23736/S0390-5616.22.05686-7","DOIUrl":"10.23736/S0390-5616.22.05686-7","url":null,"abstract":"<p><strong>Background: </strong>In approximately 15% of spontaneous subarachnoid hemorrhage (SAH) patients, no bleeding source is found in the initial imaging. These patients can be categorized as either perimesencephalic (PM-SAH) or non-perimesencephalic (NP-SAH) subarachnoid hemorrhage patients. Follow-up imaging is routinely performed after NP-SAH to detect treatable etiologies; however, the optimal follow-up imaging protocol remains unclear. This study examines the optimal time interval to re-imaging and the performance of magnetic resonance imaging and angiography (MRI/A) in this setting.</p><p><strong>Methods: </strong>In this retrospective study, the records of NP-SAH patients treated at the University Hospital of Zurich (Switzerland) from 2005 to 2018 were analyzed. Clinical and radiological data were collected. Re-imaging data was grouped according to imaging modality and divided into three time-categories after bleeding: short-term (<2 weeks), medium-term (2-8 weeks) and long-term (>8 weeks) re-imaging.</p><p><strong>Results: </strong>Eighty-one NP-SAH patients were included. In 8 patients an aneurysm was diagnosed during re-imaging via digital subtraction angiography (9.9% diagnostic yield). Five aneurysms were detected at short-term in 81 patients (6.2% short-term yield) and three at medium-term re-imaging in 27 patients (11.1% medium-term yield). No aneurysms were found after 8 weeks in 56 patients. Five of these 8 patients also received MRI/A re-imaging, which was able to show the aneurysm in all 5 cases.</p><p><strong>Conclusions: </strong>Our study emphasizes the importance of re-imaging in NP-SAH patients, which should be done both at short-term and at medium-term follow-up after the hemorrhage. Long-term re-imaging after 8 weeks might not be of diagnostic benefit. MRI/A might be considered as a possible noninvasive re-imaging modality in this setting.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9152205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Granulocyte-colony stimulating factor, a potential candidate for the treatment of Parkinson's disease. 治疗帕金森病的潜在候选药物--粒细胞集落刺激因子。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2021-05-03 DOI: 10.23736/S0390-5616.21.05314-5
Jiawen Yuan, Li-Xia Xue, Jin-Peng Ren
{"title":"Granulocyte-colony stimulating factor, a potential candidate for the treatment of Parkinson's disease.","authors":"Jiawen Yuan, Li-Xia Xue, Jin-Peng Ren","doi":"10.23736/S0390-5616.21.05314-5","DOIUrl":"10.23736/S0390-5616.21.05314-5","url":null,"abstract":"<p><strong>Background: </strong>Granulocyte colony-stimulating factor (G-CSF) activates the PI3K/Akt pathway to exert neuroprotective effects. The current study aimed to determine if G-CSF reverses behavioral deficits, even after motor malfunction occurs in Paraquat (PQ)-treated mice.</p><p><strong>Methods: </strong>Male C57BL/6 mice (8 weeks old) were divided into 3 groups: PQ + G-CSF-treated group (N.=8); PQ + saline-treated group (N.=8); and saline-treated control group (N.=8). Spontaneous locomotor activity was evaluated together with the pole test. The DA, 3, 4-dihydroxyphenyl acetic acid (DOPAC), and homovanillic acid (HVA) levels in the bilateral striatum were determined by HPLC. The number of substantia nigra pars compacta tyrosine hydroxylase (TH)-immunoreactive neurons was calculated using an unbiased cell counting stereology method, the activities of total GSH-PX and SOD, and the malondialdehyde (MDA) content were assessed.</p><p><strong>Results: </strong>After G-CSF treatment, spontaneous motor activity and the T<inf>turn</inf> and T<inf>LA</inf> times in the CSF group were significantly lower than the control group, and the striatal dopamine level in the striatum and the number of TH-positive neurons in the substantia nigra (SN) were significantly increased compared to the control group (5478±654 vs. 3647±488 DA neurons, P<0.05). Compared to the control group, the GSH-PX and SOD activities were increased, while the MDA level was significantly decreased in the SN (P<0.05).</p><p><strong>Conclusions: </strong>The data strongly suggest that G-CSF reverses behavioral deficits in PQ-treated mice with movement disorders. Thus, G-CSF may be utilized as a prospective drug candidate for the treatment of Parkinson's disease.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38942801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of dual antiplatelet therapy combining aspirin and ticagrelor in patients with undergoing intracranial stenting procedures. 在接受颅内支架手术的患者中联合使用阿司匹林和替卡格雷的双重抗血小板疗法的安全性和有效性。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-09-16 DOI: 10.23736/S0390-5616.22.05745-9
Yihui Ma, Xiangyu Zhang, Tingbao Zhang, Yu Feng, Wenyuan Zhao, Xinjun Chen
{"title":"Safety and efficacy of dual antiplatelet therapy combining aspirin and ticagrelor in patients with undergoing intracranial stenting procedures.","authors":"Yihui Ma, Xiangyu Zhang, Tingbao Zhang, Yu Feng, Wenyuan Zhao, Xinjun Chen","doi":"10.23736/S0390-5616.22.05745-9","DOIUrl":"10.23736/S0390-5616.22.05745-9","url":null,"abstract":"<p><strong>Background: </strong>Thromboembolic complications are one of the major periprocedural complications following neuroendovascular procedures. Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel remain the principal agents for prevention of thromboembolic complications. However, clopidogrel resistance is associated with higher risk of thromboembolic complications. This study investigated the safety and efficacy of DAPT with ticagrelor and aspirin in patients undergoing intracranial stenting procedures.</p><p><strong>Methods: </strong>This retrospective study was based on patients with intracranial aneurysms who undergoing intracranial stenting procedures at our institution between August 2017 and July 2020. These patients received DAPT with ticagrelor and aspirin were included. DAPT with 90 mg ticagrelor twice daily and aspirin 100 mg daily was continued for 3 months after the intracranial stenting procedure and aspirin continued for 1 year.</p><p><strong>Results: </strong>In this study, 151 patients were identified. The most common aneurysm location was the internal carotid artery with 127 (71.8%) patients. Of the 151 cases with 160 treated aneurysms, 30 (18.8%) patients were treated by flow diverters (FDs), and 130 (81.2%) by stent-assisted coiling. Five (3.3%) patients had thromboembolic complications. Intraprocedural aneurysmal rupture was observed in one patient because of coil extrusion during coil insertion. None of the patients showed a newly DAPT-related intracerebral hemorrhage. Two patients developed dyspnea, and the symptom resolved without intervention. Furthermore, ecchymoma and gastrointestinal bleeding occurred in one patient respectively. DAPT-related thromboembolic and hemorrhagic complications were not significantly different between the FD group and stent-assisted coiling group.</p><p><strong>Conclusions: </strong>In our study, DAPT combining ticagrelor and aspirin seems to be a safe and efficient treatment for preventing thromboembolic complications in patients with intracranial aneurysms, without any increase in hemorrhagic complications. Ticagrelor may be an effective alternative for patients undergoing neurointervention.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40361028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive value of neutrophil-to-lymphocyte ratio and neutrophil-to-monocyte ratio in severe traumatic brain injury: a retrospective cohort. 中性粒细胞与淋巴细胞比率和中性粒细胞与单核细胞比率在严重脑外伤中的预测价值:回顾性队列。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2023-03-08 DOI: 10.23736/S0390-5616.23.05877-0
Luiz F Matias, Murilo D Pimentel, Mateus F Medeiros, Franciani R Rocha, Marcelo V Gambetta, Samantha C Lopes
{"title":"Predictive value of neutrophil-to-lymphocyte ratio and neutrophil-to-monocyte ratio in severe traumatic brain injury: a retrospective cohort.","authors":"Luiz F Matias, Murilo D Pimentel, Mateus F Medeiros, Franciani R Rocha, Marcelo V Gambetta, Samantha C Lopes","doi":"10.23736/S0390-5616.23.05877-0","DOIUrl":"10.23736/S0390-5616.23.05877-0","url":null,"abstract":"<p><strong>Background: </strong>The neutrophil-lymphocyte ratio (NLR), the platelet-lymphocyte ratio (PLR), the lymphocyte-monocyte ratio (LMR), the neutrophil-monocyte ratio (NMR) and the systemic immune inflammation index (SII) are associated with clinical outcomes in oncological diseases, cardiovascular diseases, infectious / inflammatory diseases, endocrinological, pulmonary and brain injuries. Here, we investigate its association with hospital mortality in patients with severe traumatic brain injury.</p><p><strong>Methods: </strong>We retrospectively reviewed clinical data from patients with severe traumatic brain injury (sTBI) who were treated in our department between January 2015 and December 2020. NLR, PLR, NMR, LMR and SII data were collected between admission and day 3, as well as other indicators related. The relationship between hematological ratios and in-hospital mortality were analyzed.</p><p><strong>Results: </strong>A total of 96 patients were included in study, hospital mortality was 40.6% (N.=39). The levels of NLR on admission (D0), NLR day 1 (D1), NLR day 2 (D2), NLR day 3 (D3), NMR day 1 (D1) and NMR day (2) remained significantly higher in patients with death intra-hospital (P=0.030; P=0.038; P=0.016; P=0.048; P=0.046 and P=0.001, respectively). Multivariate logistic analysis showed that higher NLR values at admission and day 2 NMR were associated with in-hospital mortality (OR=1.120, P=0.037; and OR=1.307, P=0.004, respectively). Analysis of the recipient operating characteristic (ROC) curve showed that the NLR on admission had a sensitivity of 59.0% and a specificity of 66.7% (area under the curve 0.630, P=0.031, Youden's Index 0.26) and the NMR of day 2 had a sensitivity of 67.7% and a specificity of 70.4% (area under the curve 0.719, P=0.001, Youden's index 0.38) to predict mortality intra-hospital based on the best threshold.</p><p><strong>Conclusions: </strong>Our analysis indicates that higher NLR levels on admission and day 2 NMR are independent predictors of in-hospital mortality in patients with sTBI.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10867134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuous subcortical monitoring of motor pathways during glioma surgery with ultrasonic surgical aspirator: technical description in a single institute experience. 使用超声手术吸引器对胶质瘤手术过程中的运动通路进行皮层下连续监测:一家研究所的技术描述。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-06-28 DOI: 10.23736/S0390-5616.22.05819-2
Alessandro D'Elia, Laura Lavalle, Antonella Bua, Mario Schiano DI Cola, Marco Ciavarro, Vincenzo Esposito
{"title":"Continuous subcortical monitoring of motor pathways during glioma surgery with ultrasonic surgical aspirator: technical description in a single institute experience.","authors":"Alessandro D'Elia, Laura Lavalle, Antonella Bua, Mario Schiano DI Cola, Marco Ciavarro, Vincenzo Esposito","doi":"10.23736/S0390-5616.22.05819-2","DOIUrl":"10.23736/S0390-5616.22.05819-2","url":null,"abstract":"<p><strong>Background: </strong>Actual challenge in surgical treatment of intra-axial gliomas involving eloquent areas is maximal safe resection. Mapping and monitoring of cortical and subcortical motor functions are important tools to avoid postoperative deficits. In the present study, we present our experience with a continuous dynamic motor mapping technique pairing a traditional monopolar stimulator with a Cavitron ultrasonic surgical aspirator (CUSA) to perform a continuous stimulation of the white matter avoiding removal interruption.</p><p><strong>Methods: </strong>We describe a single center retrospective analysis of 1-year consecutive patients with intraxial tumors located adjacent to corticospinal tract and treated with surgical resection adopting \"continuous dynamic mapping technique.\" With the support of a reconstruction software (3D Slicer), we classified the extent of resection (EOR) as gross total resection (GTR) (>98%), sub-total resection (STR) (from 90% to 97%), and partial resection (<90%). Medical Research Council (MRC) grading was adopted to evaluate neurological outcomes (from 0 to 5), assessed on first postoperative day, at 1 week, 1 month and 3 months.</p><p><strong>Results: </strong>From July 2017 to July 2018, 29 patients underwent to surgical removal of intraxial tumor adjacent to motor areas, using continuous dynamic subcortical mapping. Median age was 54 years old (range 12-75 years). At preoperative MRI tractography reconstruction, mean distance between tumor and corticospinal tract was 4.4 mm (range At 1 week postoperative assessment, motor deficits were still present in 12 patients (41%). At 1 month, 10 patients (35%) had persisting deficits, which required admission to rehabilitation department. At 3 months, 4 patients (14%) had persistent motor impairment and overall 28 patients (98%) were able to walk by themselves.</p><p><strong>Conclusions: </strong>Our early experience showed that a combination of dynamic subcortical mapping with transcranial and cortical strip MEP (motor evoked potentials) monitoring is useful in tumors close to motor eloquent areas to extend surgical resection avoiding permanent consequences. However, we need for further experience to consolidate and improve this technique.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Women in neurosurgery: review of the literature combined with a gender-based analysis of the development over the past 20 years in Austria. 神经外科中的女性:文献综述,结合对奥地利过去 20 年发展的性别分析。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-06-28 DOI: 10.23736/S0390-5616.22.05766-6
Veronika Sperl, Barbara Kiesel, Marlies Bauer, Lisa I Wadiura
{"title":"Women in neurosurgery: review of the literature combined with a gender-based analysis of the development over the past 20 years in Austria.","authors":"Veronika Sperl, Barbara Kiesel, Marlies Bauer, Lisa I Wadiura","doi":"10.23736/S0390-5616.22.05766-6","DOIUrl":"10.23736/S0390-5616.22.05766-6","url":null,"abstract":"<p><strong>Background: </strong>The number of female neurosurgeons has grown over the last decades, however, a gender gap still exists in most western countries. The reasons for this gender gap remain mostly unclear. The aim of the present study was to analyze the development of the numbers of female neurosurgeons in Austria over the last 20 years in comparison to other surgical disciplines. Additionally, a literature review was performed summarizing articles reporting on women in neurosurgery.</p><p><strong>Methods: </strong>Data including male and female residents as well as board certified surgeons over the last 20 years retrieved from the Austrian Medical Association were collected. An additional PubMed query was performed focusing on literature reporting on working conditions, work-life-balance as well as data of female leading positions.</p><p><strong>Results: </strong>In 2021, 5237 surgeons were registered at the Austrian Medical Association including 258 (5%) neurosurgeons. In total, 1081 of 5237 (21%) surgeons and 61 of 253 (24%) of all Austrian neurosurgeons were female. In comparison to the percentage of women in all surgical disciplines, the number of female neurosurgeons is represented slightly above the average of 21%. According to data representing the trend of the last 20 years, the percentage of female neurosurgeons in Austria has doubled over the last 20 years. Comparably, this trend can be observed in all surgical disciplines.</p><p><strong>Conclusions: </strong>The percentage of female neurosurgeons in Austria are constantly increasing over the last 20 years, however a gender gap still exists. Consequently, studies are warranted to analyse the causes to improve the reported gender gap in Neurosurgery.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinico-pathologic predictors of dismal course in atypical meningiomas: a retrospective single-centre analysis. 非典型脑膜瘤不良病程的临床病理学预测因素:单中心回顾性分析。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-06-28 DOI: 10.23736/S0390-5616.22.05741-1
Alice Ryba, Matthias Millesi, Thomas Roetzer, Wolfgang Marik, Stefan Wolfsberger
{"title":"Clinico-pathologic predictors of dismal course in atypical meningiomas: a retrospective single-centre analysis.","authors":"Alice Ryba, Matthias Millesi, Thomas Roetzer, Wolfgang Marik, Stefan Wolfsberger","doi":"10.23736/S0390-5616.22.05741-1","DOIUrl":"10.23736/S0390-5616.22.05741-1","url":null,"abstract":"<p><strong>Background: </strong>Despite continuous refinement of the WHO Classification for meningiomas, the biological behavior of atypical meningiomas remains difficult to predict on the basis of this grading system alone. The aim of this study was to investigate the prognostic significance of clinical and radiological parameters in a series of atypical meningioma with long follow-up of minimum 5 years.</p><p><strong>Methods: </strong>Of 1675 meningiomas treated at the Medical University Vienna (Austria) between 1993 and 2015, 179 were atypical meningioma. Of those, 93 patients were identified with follow-up of ≥5 years. Patients were grouped by recurrence and evaluated for overall and progression free survival as well as potential prognostic parameters such as age, gender, tumor size and location, edema, irregular surface, contrast enhancement, bone invasion and hyperostosis, necrosis, EOR and MIB-1.</p><p><strong>Results: </strong>From 42 (45%) patients in group recurrent and 51 (55%) patients in group non-recurrent, seven independent factors were associated with decreased progression-free survival in univariate analysis: size ≥5 cm, age ≥60 years, male gender, subtotal resection, irregular surface, and necrosis on magnetic resonance imaging, and MIB-1≥6%. In multivariable analysis, only larger size, older age, necrosis and higher MIB-1 remained independent prognostic risk factors for recurrence of atypical meningioma.</p><p><strong>Conclusions: </strong>We identified larger size, older age, presence of necrosis on magnetic resonance imaging, and higher MIB-1, as detrimental parameters for recurrence of atypical meningioma. Until molecular profiling of atypical meningioma becomes routinely available, these parameters may aid the clinician in decision making about surveillance intervals and adjuvant radiation treatment.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nerve high-resolution ultrasound in a 2-year follow-up of radial nerve palsy related to humeral shaft fractures. 神经高分辨率超声在与肱骨轴骨折相关的桡神经麻痹两年随访中的应用。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-06-28 DOI: 10.23736/S0390-5616.22.05781-2
Luca Leonardi, Simona Loreti, Antonella DI Pasquale, Laura Fionda, Fiammetta Vanoli, Stefania Morino, Matteo Garibaldi, Girolamo Alfieri, Antonio Lauletta, Marco Salvetti, Giovanni Antonini
{"title":"Nerve high-resolution ultrasound in a 2-year follow-up of radial nerve palsy related to humeral shaft fractures.","authors":"Luca Leonardi, Simona Loreti, Antonella DI Pasquale, Laura Fionda, Fiammetta Vanoli, Stefania Morino, Matteo Garibaldi, Girolamo Alfieri, Antonio Lauletta, Marco Salvetti, Giovanni Antonini","doi":"10.23736/S0390-5616.22.05781-2","DOIUrl":"10.23736/S0390-5616.22.05781-2","url":null,"abstract":"<p><strong>Background: </strong>High-resolution nerve ultrasonography (HRUS) could have an emerging importance in diagnosis and follow-up of axonopathic radial palsy associated with humeral shaft fractures due to closed trauma. The aim of our study was to establish the role of HURS in this context through a longitudinal multimodal analysis.</p><p><strong>Methods: </strong>Clinical, electrodiagnostic (EDX) and HRUS evaluations were prospectively performed at month 1, 3, 6, 12 and 24 from injury, in a continuous series of 19 patients collected in a 5-year study. Clinical severity was scored on MRC of involved muscles, EDX on presence/absence of functional continuity; anatomical continuity and nerve cross sectional area (NCSA) of radial (RN) and posterior interosseus (PIN) nerves were evaluated through HRUS.</p><p><strong>Results: </strong>All patients showed clinical improvement during follow-up; EDX functional continuity was reached by all patients within 12 months; HRUS revealed RN anatomical continuity in all patients and PIN involvement in 74%. RN NCSA progressively reduced during FU, but it was still significantly higher than contralateral at month 24; PIN NCSA became normal within 24 months.</p><p><strong>Conclusions: </strong>When anatomical RN continuity is confirmed by HRUS, good functional outcome is reached even in patients with EDX loss of functional continuity. Together with clinical and EDX evaluations, HRUS may provide useful data in the follow-up of radial palsy due to humeral shaft fractures.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40408783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Specifies of the fetal median callosal artery. 明确胎儿胼胝体中动脉的位置。
IF 1.3 4区 医学
Journal of neurosurgical sciences Pub Date : 2024-10-01 Epub Date: 2022-09-09 DOI: 10.23736/S0390-5616.22.05820-9
Ljiljana Vasović, Ana Mrkaić, Milena M Trandafilović, Martina Drevenšek
{"title":"Specifies of the fetal median callosal artery.","authors":"Ljiljana Vasović, Ana Mrkaić, Milena M Trandafilović, Martina Drevenšek","doi":"10.23736/S0390-5616.22.05820-9","DOIUrl":"10.23736/S0390-5616.22.05820-9","url":null,"abstract":"<p><strong>Background: </strong>A variable artery in the anterior cerebral circulation, named median callosal artery (MdCA) belongs to one of the three groups of anteromedial central branches of the anterior communicating artery (ACoA). The lack of information on MdCA in human fetuses inspired the authors to explore and present its morphological features.</p><p><strong>Methods: </strong>The arteries of the brain base were analyzed and measured on 193 specimens of human fetuses, whose values are preserved from the time of preparation of PhD thesis.</p><p><strong>Results: </strong>The median callosal artery was observed in 45% (87/193) of fetuses from 12.5 to 25 weeks of gestation. The MdCA originating from the single ACoA was found in 4.66% cases. MdCAs originating from the so-called anterior communicating rete (16.58%), as well from the partially duplicated (5.69%) and total duplicated ACoA (10.88%) were also found. A statistically significant difference of the artery OD between male and female fetuses was not found. There was a non-significant positive correlation between fetal age presented in gestational weeks and the artery OD (r=0.214). The OD of the MdCA did not correlate with the diameters of the anterior cerebral artery (ACA). An unusual convergent union of initial ACA medial vessels and partial duplication at MdCA beginning and its trunk fenestrations were shown, along with bilateral distribution of MdCA branches.</p><p><strong>Conclusions: </strong>The wide range of variability of the median callosal artery in human fetuses, presented in this paper, contributes to anatomical knowledge on the anterior part of cerebral circulation.</p>","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33455180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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