Shraddha Sudhir, Kharma C Foucher, Pim Jetanalin, Lindsay Slater Hannigan
{"title":"Ischemic Preconditioning Improves Hip Abductor Strength and Power in Patients with Symptomatic Knee Osteoarthritis.","authors":"Shraddha Sudhir, Kharma C Foucher, Pim Jetanalin, Lindsay Slater Hannigan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of ischemic preconditioning (IC) on bilateral hip abductor strength, fatigue, and power in patients with knee osteoarthritis (KOA).</p><p><strong>Methods: </strong>Participants (n=10) with KOA completed isokinetic and isometric hip abductor assessments on a Biodex dynamometer both before and after IC. IC was administered during a single session and consisted of 5 minutes of inflation (225mmHg) followed by 5 minutes of reperfusion for 50 minutes. Changes in strength and endurance measures before and after IC were compared using paired t-tests and magnitude of significant differences were reported using Cohen's d effect sizes.</p><p><strong>Results: </strong>Isokinetic hip abductor peak torque (d=.42, p=.027) and average power (d=.57, p=.029) in the involved limb, and isokinetic peak torque (d=.37, p=.044) in the uninvolved limb increased significantly after IC compared to baseline. There were no changes in isokinetic average power in the uninvolved limb, or isometric peak torque and fatigue index in both limbs after IC (p=.13-.77).</p><p><strong>Conclusions: </strong>A single session of IC improved hip abductor strength in both limbs and power in the involved limb in KOA patients. IC should continue to be investigated as a safe and clinically convenient intervention that can supplement traditional modalities to improve muscle function in KOA.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"353-360"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which Bone-Modifying Agents Are Most Effective in Reducing Bone Loss in Women with Early and Locally Advanced Breast Cancer? - A Cochrane Review summary with commentary.","authors":"Ekin Ilke Sen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"332-335"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bridging Dynamic Neuromuscular Stabilization Synergism with Movement Control Impairment Related Non-Specific Low Back Pain: Scoping Review.","authors":"Manju Kaushik, Irshad Ahmad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Non-specific chronic low back pain (NSCLBP) with movement control impairment (MCI) subgroup often experiences postural pain and functional lumbar spine instability. This scoping review had two aims: 1) to map the evidence related to dynamic neuromuscular stabilization (DNS) efficacy as a spinal stabilization strategy and to identify gaps in the literature that may exist regarding the effectiveness of DNS in low back pain management and 2) to align the DNS approach as a potential intervention for MCI patients. The clinical trial studies related to DNS exercises were searched from inception until February 2024 through electronic databases, such as PubMed, Google Scholar, PEDro, and Science Direct. The Arksey and O'Malley methodology and PRISMA-ScR checklist were followed to report the findings. A total of 18 studies offering a total sample of 483, were included based on the inclusion criteria. The results of 14 studies summarized the DNS-related influence on neural substrates and core stability. The availability of only 4 studies on DNS efficacy in chronic low back pain indicates a dearth of evidence. This review highlighted the DNS efficacy in improving core muscle activation and pain-related symptoms in NSCLBP patients while emphasising the need for prospective research in the MCI subgroup.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"420-432"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cesar Sordo-Vacas, Amador Garcia-Ramos, David Colomer-Poveda
{"title":"Intra and Inter-Session Reliability of Movement Velocity During Pull-Ups Performed at Small Climbing Holds.","authors":"Cesar Sordo-Vacas, Amador Garcia-Ramos, David Colomer-Poveda","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The synergy between arm and shoulder muscles, along with isometric finger flexor strength, are crucial for climbing proficiency. However, tests often assess these factors separately rather than in a unified action. This study aimed to determine the intra- and inter-session reliability of the mean propulsive velocity (MPV) during pull-ups on a large hold and on small climbing edges.</p><p><strong>Methods: </strong>Ten male climbers (self-reported maximal grade 6b-8b on French scale) participated in two identical sessions. During each session, participants performed two blocks of two pull-ups on a large hold and on four small climbing edges (25, 20, 15, and 10mm) in randomized order. The MPV was recorded using a linear position transducer.</p><p><strong>Results: </strong>The MPV during climbing pull-ups at 20mm (0.75±0.16 m/s), 15mm (0.73±0.16 m/s), and 10mm (0.52±0.15 m/s) was reduced compared to a pull-up on a large hold (0.84±0.16m/s). Intraclass correlation coefficients (ICCs) were good-to-excellent across hold sizes for intra-session (ICC 0.84-0.99) and inter-session (ICC 0.73-0.96) measurements.</p><p><strong>Conclusions: </strong>The results suggest that the MPV assessed during climbing-specific pull-ups on small holds provides valuable insights into finger, elbow and shoulder muscle force capacities in a unified action. This test could be considered a sport-specific test for monitoring performance in climbers.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"370-376"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia Ferfeli, Antonios Galanos, Ismene A Dontas, Dimitrios Pitidis-Poutous, Ioannis K Triantafyllopoulos, Zaira Symeonidou, Damiani Tsiamasfirou, Efstathios Chronopoulos
{"title":"Respiratory Muscle Strength Correlation with Functional Capacity, Quality of Life, Demographics and Co-morbidities in Stroke and Spinal Cord Injury.","authors":"Sofia Ferfeli, Antonios Galanos, Ismene A Dontas, Dimitrios Pitidis-Poutous, Ioannis K Triantafyllopoulos, Zaira Symeonidou, Damiani Tsiamasfirou, Efstathios Chronopoulos","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To record Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) in neuro-rehabilitation patients and establish correlation with functional status, quality of life, demographics and co-morbidities.</p><p><strong>Methods: </strong>Respiratory muscle strength was measured in 50 stroke patients and 50 spinal cord injury (SCI) patients. Both groups were evaluated with the Modified Barthel Index (MBI-Shah version) and the 36-Item Short Form Survey. Demographics, medical history, history of moderate physical activity prior to injury and American Spinal Injury Association (ASIA) classification were recorded.</p><p><strong>Results: </strong>Respiratory muscle strength declined with age and males exhibited higher MIP and MEP in the SCI group and higher MEP, but not MIP, in stroke. In the ASIA D SCI subgroup, the MBI total score was moderately positively correlated with MIP and MEP values. In stroke, MBI total score and MEP were positively correlated in both sexes and MBI total score and MIP in females. Diabetes mellitus absence correlated with higher MIP and MEP in SCI. Prior physical activity was linked to higher MIP, MEP in stroke and to higher MIP in SCI.</p><p><strong>Conclusions: </strong>Age, sex, functional capacity, SCI classification, quality of life components, history of physical activity and diabetes influence respiratory muscle strength in the studied population.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"361-369"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender-specific Indian Paediatric and Adult Reference Data for Muscle Function Parameters Assessed Using Jumping Mechanography.","authors":"Sonal Kasture, Vaman Khadilkar, Vivek Patwardhan, Anuradha Khadilkar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To establish age and gender-specific paediatric and adult reference data for muscle function parameters assessed using Jumping Mechanography in the Indian population.</p><p><strong>Methods: </strong>2056 healthy individuals (1068 males), aged 5 to 60 years, performed 2 tests on a force platform (Leonardo Mechanograph, Novotec). Maximum power (Pmax) was assessed by single two legged jump and maximum force (Fmax) by multiple one legged hopping. LMS method was used to generate age and gender-specific reference curves for 5 - 20y group and mean ± SD and median ± IQR are presented for 21 - 60y group.</p><p><strong>Results: </strong>In 5 - 20y group, Pmax and Fmax increased with age while in 21 - 60y group, the parameters declined with age. Females had lower Pmax values than males, consistently through all age groups. In children <15y, there were no intergender differences in Fmax, however, in further age groups, females had lower Fmax (p<0.001). Our participants showed lower Pmax and Fmax when compared with machine reference data based on German population (p<0.001).</p><p><strong>Conclusion: </strong>We present ethnicity-specific reference values for muscle function by Jumping Mechanography. These values are intended to help in clinical assessment of muscle function of Indian population and to identify those at risk of poor muscle function.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 3","pages":"243-258"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparative Study of the Early Postoperative Outcome of Three Intramedullary Fixation Modalities in the Treatment of Intertrochanteric Fractures of the Femur in the Elderly.","authors":"Hongpei Fu, Lang Hu, Feng Zou, Xiaolong Liao, Yongling Zheng, Peicheng Jin, Junjie Jia, Junchang Xu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To compare early outcomes of proximal femoral bionic nail (PFBN), Inter-TAN, proximal femoral nail antirotation (PFNA) for intertrochanteric fractures in elderly patients.</p><p><strong>Methods: </strong>Eighty-two elderly patients with intertrochanteric femoral fractures treated at Xiangyang No. 1 People's Hospital affiliated with Hubei University of Medicine from December 2021 to 2022 were retrospectively analyzed. They were categorized into three surgical groups: PFBN (22 cases), Inter-TAN (20 cases), and PFNA (40 cases). Preoperative demographics and fracture characteristics were compared, alongside intraoperative and postoperative metrics like operative time and complication rates.</p><p><strong>Results: </strong>In the PFBN group, operative time, fluoroscopy use, blood loss, and transfusion were higher, but postoperative weight-bearing, healing, and hospital stay were shorter compared to the Inter-TAN and PFNA groups (P<0.05). Inter-TAN had a significantly shorter postoperative weight-bearing time than PFNA (P<0.001). Other compared factors showed no significant differences between groups (P>0.05), including complication rates and scores at 6-month follow-up.</p><p><strong>Conclusions: </strong>PFBN, a novel surgical approach for intertrochanteric fractures in elderly patients, outperforms Inter-TAN and PFNA by accelerating early weight-bearing and hastening fracture recovery.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 3","pages":"310-317"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenhao Dai, Yibing Liu, Junjie Chang, Na Cao, Xi Zhang, Jun Gao
{"title":"Analysis of Pathological Factors of Long Head of Biceps Tendinopathy Based on Network Pharmacology.","authors":"Wenhao Dai, Yibing Liu, Junjie Chang, Na Cao, Xi Zhang, Jun Gao","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the therapeutic effect and mechanism of Danggui Buxue Tang in the treatment of biceps longus tendon lesions, and to preliminarily explore the relevant factors affecting this injury.</p><p><strong>Methods: </strong>Using network pharmacology analysis methods, the potential mechanism of Danggui Buxue Tang in treating key lesions of the long head of the biceps brachii muscle was studied.</p><p><strong>Results: </strong>Model analysis revealed 44 protein-protein interactions associated with long head binding. The distribution of 19 strongly correlated targets is Pharmaper>SEA>Stitch>Swiss. Further discovery revealed 17 immune system and inflammation related KEGG pathways with P values less than 0.01. The TNF and sphingolipid signaling pathways are associated with inflammation, while the MAPK signaling pathway is associated with immunity. Finally, it was found that the FoxO and HIF-1 signaling pathways are directly associated with long head restraint injury in the biceps brachii muscle.</p><p><strong>Conclusion: </strong>Danggui Buxue Tang inhibits related pathways, regulates the immune system, reduces inflammation, and alleviates disease progression. Danggui Buxue Tang can be an effective choice for treating combined lesions of the long head of the biceps brachii muscle.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 3","pages":"291-300"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefanie Steven, Karoline Spiess, Bruno Lentzen, Nina Reinhart, Eckhard Schoenau, Ibrahim Duran
{"title":"Effect of a Rehabilitation Program Including Home-Based Vibration-Assisted Therapy on Gait Parameters in Children with Cerebral Palsy.","authors":"Stefanie Steven, Karoline Spiess, Bruno Lentzen, Nina Reinhart, Eckhard Schoenau, Ibrahim Duran","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to examine the effects of a rehabilitation program combined with a home-based vibration-assisted therapy on gait parameters in children with cerebral palsy (CP).</p><p><strong>Methods: </strong>In a retrospective study, 180 children, 101 boys and 79 girls, (mean age 7.2 ± 3.3 years) with CP at Gross Motor Function Classification System (GMFCS) Level I and Level II were examined using gait analyses with the Leonardo Mechanograph® Gangway at three measurement points. The measurements were conducted before (M0) and after a six-month rehabilitation period (M6), as well as 12 months after the commencement of rehabilitation (M12). The difference between measurement points M6-M0 (treatment interval) and M12-M6 (follow-up interval) were compared, and significance was determined using the Wilcoxon test.</p><p><strong>Results: </strong>Children with CP at GMFCS Level I and II demonstrated a significant improvement in gait efficiency (pathlength/distance M6-M0: -0.053 (SD 0.25) vs M12-M6: -0.008 (0.36), p=0.038). There were no significant difference in change of mean velocity and average step length between M6-M0 and M12-M6 (p=0.964 and p=0.611).</p><p><strong>Conclusions: </strong>The rehabilitation program seems to enhance gait efficiency in children with CP. German Clinical Trial Registry: DRKS0001131 at www.germanctr.de.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 3","pages":"259-266"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yannis Dionyssiotis, Konstantinos Prokopidis, Melina Longoni Di Giusto, Andrea Olascoaga-Gómez De León, Roberto Coronado-Zarco, Nicola Manocchio, Belgin Erhan, Calogero Foti
{"title":"Neglecting Bone Health: A Critical Gap in Management of Muscle Spasticity with Botulinum Toxin in Spinal Cord Injury.","authors":"Yannis Dionyssiotis, Konstantinos Prokopidis, Melina Longoni Di Giusto, Andrea Olascoaga-Gómez De León, Roberto Coronado-Zarco, Nicola Manocchio, Belgin Erhan, Calogero Foti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neuromuscular inhibitors have been quickly advanced from being used only for aesthetic purposes to being used as a treatment for musculoskeletal pain and muscle spasticity. This phenomenon stems from the diminished force exerted by muscles, which are essential for bone remodeling. In this context, it is hypothesized that botulinum toxin (BTX) might exert a direct influence on bone resorption. Although such treatments have the potential to provide patients with significant relief, bone loss occurring due to elective muscle paralysis has yet to be examined in clinical trials. The disuse model resulting from spinal cord injury, characterized by the absence of ground reaction and muscle forces, provides an ideal context for exploring the skeletal ramifications of intramuscular BTX injection. This approach enables an investigation into the intricate interplay between muscle and bone, encompassing the impact of spasticity on bone preservation, the potential positive and negative outcomes of BTX on bone metabolism, and the involvement of the autonomic nervous system in bone remodeling regulation. This paper presents a narrative review of research findings on the disturbance of the typical balance between muscles and bones caused by acute muscle paralysis from BTX, resulting in osteopenia and bone resorption.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 3","pages":"318-324"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}