Journal of nanoscience and nanotechnology最新文献_第10页

Application of Carbon Nanoparticle Tracers in the Lateral Neck Lymph Nodes of CN1bx Patients with Papillary Thyroid Carcinoma. 纳米碳示踪剂在CN1bx甲状腺乳头状癌患者侧颈淋巴结中的应用。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19472

XiaoYu Qian, Jian Tang, Yongquan Chu, Liang Chen, Ziqiang Chen, Lin Li

{"title":"Application of Carbon Nanoparticle Tracers in the Lateral Neck Lymph Nodes of CN1bx Patients with Papillary Thyroid Carcinoma.","authors":"XiaoYu Qian, Jian Tang, Yongquan Chu, Liang Chen, Ziqiang Chen, Lin Li","doi":"10.1166/jnn.2021.19472","DOIUrl":"https://doi.org/10.1166/jnn.2021.19472","url":null,"abstract":"This study aimed to investigate the applicability of carbon nanoparticle tracers in the lateral neck lymph nodes of CN1bx patients with papillary thyroid carcinoma surgery. 73 patients with papillary thyroid carcinoma at our hospital between January 2019 to December 2019 were suspected metastasis in the lateral neck lymph node before surgical treatment. During the operation, carbon nanoparticle tracers were used as black staining tracers for the lateral neck lymph nodes to detect metastasis in each Compartment of the neck. The lateral Compartment is defined as level ll-V The black-stained lymph nodes, dyed by Carbon nanoparticle tracers, and non-dyed lymph nodes were compared. Post-surgery paraffin pathology was adopted as the gold standard to calculate the predictive performance of the carbon nanoparticle tracers in detecting lymph node biopsy metastasis. 59 of the patients (80.8%) had lateral neck metastasis. The black-stained lymph nodes, dyed by Carbon nanoparticle tracers, in Compartment IV exhibited the highest proportions in the case number submitted for detection and in lymph nodes metastasis, followed by Compartment III. The metastasis rate of the dyed lymph nodes in areas III and IV was significantly higher than that of non-dyed lymph nodes (P < 0.05). The sensitivity and accuracy of the dyed lymph node biopsy in Compartments III-IV were 90% and 93.2%, respectively. This predictive performance was similar to that Compartments ll-V combined. In conclusion, when carbon nanoparticle tracers are used for lymph node biopsy, high sensitivity and accuracy are obtained in lateral neck compartments III-IV, making these compartments ideal for lymph node biopsy.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5408-5413"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38985942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mixed Poloxamer Nanomicelles for the Anticonvulsant Lamotrigine Drug: Solubility, Micellar Characterization, and In-Vitro Release Studies. 抗惊厥药物拉莫三嗪的混合波洛沙姆纳米胶束:溶解度、胶束表征和体外释放研究。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19490

Sofiya Shaikh, Hemil Patel, Debes Ray, Vinod K Aswal, Rakesh K Sharma

{"title":"Mixed Poloxamer Nanomicelles for the Anticonvulsant Lamotrigine Drug: Solubility, Micellar Characterization, and In-Vitro Release Studies.","authors":"Sofiya Shaikh, Hemil Patel, Debes Ray, Vinod K Aswal, Rakesh K Sharma","doi":"10.1166/jnn.2021.19490","DOIUrl":"https://doi.org/10.1166/jnn.2021.19490","url":null,"abstract":"Recently the applications of Poloxamers in drug development is promising as it facilitated the drug molecule for delivering to the correct place, at the correct time and in the correct amount. Poloxamers can form nanomicelles to encapsulate hydrophobic drugs in order to increase solubility, stability and facilitate delivery at target. In this context, the solubilization of anticonvulsant lamotrigine (LMN) drug in a chain of Poloxamers containing different polyethylene oxide and polypropylene oxide noieties were examined. The results showed better solubilization of LMN in Poloxamers contain low CMTs while poor with Poloxamers having high CMTs. Systematic investigation of two mixed Poloxamer nanomicelles (P407:P403 and P407:P105) for LMN bioavailability at body temperature (37 °C) were investigated. The solubility of LMN was enhanced in mixed P407:P403 nanomicelles with the amount of P403 and reduced in mixed P407:P105 nanomicelles with the amount of P105. LMN encapsulated mixed Poloxamer nanomicelles were found spherical in shape with ~25 nm Dh sizes. The In-Vitro release profiles of mixed Poloxamer nanomicelles demonstrated the biphasic model with initial burst release and then slowly release of LMN. Better biocompatibility of LMN in the mixed P407:P403 nanomicelles was confirmed with stability data. The results of this work were proven the mixed P407:P403 nanomicelles as efficient nanocarriers for LMN.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5723-5735"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38905207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Pulse-Modulated Plasma Etching of Copper Thin Films via CH₃COOH/Ar. CH₃COOH/Ar等离子体刻蚀铜薄膜的研究。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19462

Jin Su Ryu, Eun Taek Lim, Moon Hwan Cha, Chee Won Chung

引用次数: 0

UV Light Activated Multi-Cycle Photoelectric Properties of TiO₂ and CdS/TiO ₂ Films in Formaldehyde. 紫外光在甲醛中活化TiO 2和CdS/TiO 2膜的多周期光电性质

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19465

Zhijun Zou, Zhongli Qu, Longtao Tang, Yang Qiu, Gaohua Liao, Chang Li, Fen Li, Jiayou Tao

{"title":"UV Light Activated Multi-Cycle Photoelectric Properties of TiO₂ and CdS/TiO ₂ Films in Formaldehyde.","authors":"Zhijun Zou, Zhongli Qu, Longtao Tang, Yang Qiu, Gaohua Liao, Chang Li, Fen Li, Jiayou Tao","doi":"10.1166/jnn.2021.19465","DOIUrl":"https://doi.org/10.1166/jnn.2021.19465","url":null,"abstract":"In this work, UV light activated multi-cycle photoelectric properties of TiO₂ and CdS/TiO₂ films in formaldehyde were researched. TiO₂ film was prepared by screen printing, CdS/TiO₂ compounded film was synthesized by SILAR method. XRD and FE-SEM was used to characterize the TiO₂ and CdS/TiO₂ samples. Multi-cycle photoelectric properties of TiO₂ and CdS/TiO₂ with uv light on and off were evaluated by testing the photocurrent. On one hand, under the same bias voltage, CdS/TiO ₂showed a higher photocurrent than that by TiO₂. The reason for this result should be ascribed to the compounded structure in CdS/TiO₂, with which the separation and transfer of photogenerated electron-hole pairs could be improved. On the other hand, with the testing cycle number increased, the photocurrent amplitudes of TiO₂ and CdS/TiO₂ increased. These results suggested that the time to reach a stable photocurrent value for TiO₂ and CdS/TiO₂ is much longer than one cycle time (300 S). To illustrate the increased photocurrent amplitude value cycle by cycle, the photocurrent of CdS/TiO₂ to a much longer time (more than 4000 seconds) was also tested. To explain these results, corresponding possible illustrations were presented.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5642-5647"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38893158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Characterization and Optical Properties of ZnO Nanoparticles Doped with Er and Yb. 掺铒镱氧化锌纳米粒子的合成、表征及光学性能

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19489

S Fuentes, D Espinoza, J León

引用次数: 2

Fabrication of High Dielectric Materials Through Selective Insertion of Functionalized Reduced Graphene Oxide on Hard Segment of Thermoplastic Polyurethane. 功能化还原氧化石墨烯选择性插入热塑性聚氨酯硬段制备高介电材料。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19468

Rakesh Manna, Suneel Kumar Srivastava, Vikas Mittal

{"title":"Fabrication of High Dielectric Materials Through Selective Insertion of Functionalized Reduced Graphene Oxide on Hard Segment of Thermoplastic Polyurethane.","authors":"Rakesh Manna, Suneel Kumar Srivastava, Vikas Mittal","doi":"10.1166/jnn.2021.19468","DOIUrl":"https://doi.org/10.1166/jnn.2021.19468","url":null,"abstract":"The presence of microcapacitors near percolatrion threshold determines dielectric permittivity of a material. Motivated by this concept, we focused our work by preferentially allocating functionalized reduced graphene oxide (FRGO) in hard segment (disperse phase) of Thermoplastic polyurethane (TPU) by solution blending method and characterized. Morphological studies of TPU/FRGO nanocomposites established homogeneous dispersion of FRGO throughout the TPU matrix. It is noted that TPU/FRGO (1 phr) nanocomposites exhibit maximum increase in tensile strength (33%) and elongation at break (10%). Thermogravimetric analysis (TGA) showed maximum enhancement in onset of decomposition temperature (~6 °C) in 2 phr FRGO loaded TPU. Differential scanning calorimetry (DSC) analysis showed maximum reduction (~2 °C) in glass transition temperature (Tg) of soft segment of TPU followed by maximum improvements in melting temperature (~4 °C) as well as crystallization temperature (~22 °C) of hard segment compared to neat TPU. Further, a significantly high value of dielectric permittivity (401) is achieved in 1.5 phr loaded FRGO at 100 Hz due to the formation of significantly higher number of microcapacitors near the percolation threshold. It is anticipated that such thermally stable and mechanically strong high dielectric TPU/FRGO nanocomposites can find applications in the field of electronic devices.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5569-5582"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38974945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyelectrolyte Multi-Layered Griseofulvin Nanoparticles: Conventional versus Continuous In-Situ Layer-by-Layer Fabrication. 聚电解质多层灰黄霉素纳米颗粒:传统与连续原位逐层制备。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19453

Sumayah Abdul-Jabbar, Gary P Martin, Luigi G Martini, Jayne Lawrence, Paul G Royall

{"title":"Polyelectrolyte Multi-Layered Griseofulvin Nanoparticles: Conventional versus Continuous In-Situ Layer-by-Layer Fabrication.","authors":"Sumayah Abdul-Jabbar, Gary P Martin, Luigi G Martini, Jayne Lawrence, Paul G Royall","doi":"10.1166/jnn.2021.19453","DOIUrl":"https://doi.org/10.1166/jnn.2021.19453","url":null,"abstract":"Polyelectrolyte multilayers are promising drug carriers with potential applications in the delivery of poorly soluble drugs. Furthermore, the polyelectrolyte multilayer contributes towards electrostatic interactions, which enhances the physical and chemical stability of colloids when compared to those prepared by other approaches. The aim of this work was to generate a polyelectrolyte multilayer on well characterised nanoparticles of the poorly water-soluble drug, griseofulvin. Griseofulvin (GF) nanoparticles (300 nm) were produced by wet bead milling, bearing a negative surface charge due to the use of poly(sodium 4-styrenesulfonate) (PSS) as a stabiliser. Six further layers of alternating chitosan and PSS polyelectrolyte multilayer were successfully generated at the particle surface either via use of: (1) the conventional method of adding excess coating polymer followed by centrifugation, or (2) the continuous in situ approach of adding sufficient amount of coating polymer. The continuous in situ method was designed de novo by the consecutive addition of polymers under high shear rate mixing. In comparison to the continuous in situ method, the conventional method yielded nanoparticles of smaller size (282 ±9 nm vs. 497 ±34 nm) and higher stability by maintaining its size for 6 months. In conclusion, the parent griseofulvin nanosuspension proved to be a suitable candidate for the polyelectrolyte multilayer fabrication providing an avenue for a bespoke formulation with versatile and potentially enhanced drug delivery properties.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5611-5621"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38974949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Bovine Serum Albumin Conjugation in Superparamagnetic/Poly(methyl methacrylate) Nanoparticles as an Alternative for Magnetic Enzyme-Linked Immunosorbent Assays. 牛血清白蛋白在超顺磁/聚甲基丙烯酸甲酯纳米颗粒中的偶联作为磁性酶联免疫吸附测定的替代方法。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19458

Paulo Emilio Feuser, Camila Guindani, Jonathann Correa Possato, Jaqueline Pereira Guessi, Arthur Poester Cordeiro, Ricardo Andrez Machado-de-Ávila, Claudia Sayer, Pedro Henrique Hermes de Araújo

{"title":"Bovine Serum Albumin Conjugation in Superparamagnetic/Poly(methyl methacrylate) Nanoparticles as an Alternative for Magnetic Enzyme-Linked Immunosorbent Assays.","authors":"Paulo Emilio Feuser, Camila Guindani, Jonathann Correa Possato, Jaqueline Pereira Guessi, Arthur Poester Cordeiro, Ricardo Andrez Machado-de-Ávila, Claudia Sayer, Pedro Henrique Hermes de Araújo","doi":"10.1166/jnn.2021.19458","DOIUrl":"https://doi.org/10.1166/jnn.2021.19458","url":null,"abstract":"Nanomaterials, such as magnetic nanoparticles have attracted significant attention of medical area due to their capacity to improve the performance of immunoassays. Therefore the aim of this work was to study the bovine serum albumin (BSA) conjugation in superparamagnetic (MNPs)/poly(methyl methacrylate) (PMMA) nanoparticles with further characterization and application in enzyme-linked immunosorbent (ELISA) assay. The successful conjugation of BSA in MNPs- PMMA nanoparticles was confirmed by several techniques, including light scattering, zeta potential, transmission electron microscopy (TEM) and Lowry protein quantification assay. The superparamagnetic properties were confirmed by vibrating sample magnetometer. BSA conjugated MNPs-PMMA nanoparticles presented higher interactions with antibody than free BSA. The BSA + MNPs-PMMA nanoparticles (magnetic ELISA assay) reduced the time and increased the sensibility of traditional ELISA assay, reinforcing the idea that the use these nanomaterials are an excellent alternative for the immunoassays field.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5493-5498"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38975551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Free Fatty Acid from Waste Palm Oil Functionalized Magnetic Nanoparticles Immobilized on Surface Graphene Oxide as a New Adsorbent for Simultaneously Detecting Hazardous Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Food Extracts. 氧化石墨烯表面固定化废棕榈油游离脂肪酸功能化磁性纳米颗粒作为同时检测食品提取物中有害多环芳烃和邻苯二甲酸酯的新型吸附材料。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19454

Sharifah Mohamad, Shabnam Bakhshaei, Ninie Suhana Abdul Manan, N A Parmin, Siti Khalijah Mahmad Rozi

{"title":"Free Fatty Acid from Waste Palm Oil Functionalized Magnetic Nanoparticles Immobilized on Surface Graphene Oxide as a New Adsorbent for Simultaneously Detecting Hazardous Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Food Extracts.","authors":"Sharifah Mohamad, Shabnam Bakhshaei, Ninie Suhana Abdul Manan, N A Parmin, Siti Khalijah Mahmad Rozi","doi":"10.1166/jnn.2021.19454","DOIUrl":"https://doi.org/10.1166/jnn.2021.19454","url":null,"abstract":"A newly synthesized free fatty acids from waste palm oil functionalized magnetic nanoparticles immobilized on the surface of graphene oxide (FFA@MNP-GO) was successfully synthesized and characterized in this research. The combinations of long alkyl chain of free fatty acid with graphene oxide that consists of large delocalized 77-electron systems and abundant of hydrophilic groups with hydroxyl, epoxide and carboxylic groups offer the determination of simultaneous wide range of polarities of organic pollutants in real matrices through hydrogen bonding, hydrophobic and 77-77 interactions. The fabricated adsorbent was successfully applied as a magnetic solid phase extraction (MSPE) adsorbent for the simultaneous separation of selected phthalate esters (PAEs) and polycyclic aromatic hydrocarbons (PAHs) in apple and cabbage extracts prior to their high performance liquid chromatography with diode-array detector (HPLC-DAD) determination. Factors affecting the extraction efficiency such as amount of adsorbent, desorption solvent, volume of desorption solvent, extraction time, desorption time, pH and sample volume were investigated and optimized. The results revealed that under optimal conditions, the detection limit of selected PAEs and PAHs were in the range of 0.56-0.97 ng mL-1 and 0.02-0.93 ng mL-1, respectively. The spiked recoveries of real apple and cabbage extracts for PAEs and PAHs were in the range of 81.5-117.6% with good relative standard deviation (RSD) (n = 5) less than 10% and 86.7-118.2% with acceptable RSDs (n = 5) ranging from 1.5 to 11.0%, respectively. This study reported for the first time the use of MSPE procedure for simultaneous determination of chosen PAHs and PAEs in real samples including apple and cabbage extracts by using new adsorbent, FFA@MNP-GO.","PeriodicalId":16417,"journal":{"name":"Journal of nanoscience and nanotechnology","volume":"21 11","pages":"5522-5534"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38975554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Amino Acid Dependent Performance of Modified Chitosan Against Bacteria and Red Blood Cell. 改性壳聚糖对细菌和红细胞的氨基酸依赖性研究。

Journal of nanoscience and nanotechnology Pub Date : 2021-11-01 DOI: 10.1166/jnn.2021.19480

Xiaoyan Ju, Lu Tian, Xuantong Duan, Zhuang Li, Yongping Han, Ye Tian, Zhongwei Niu

引用次数: 1