S. Soetrisno, Ismarwati Ismarwati, Hafi Nurinasari
{"title":"The Effectiveness of Community Development Model by Using Whatsapp toward Old Women Behavior in Early Detection of Cervical Cancer","authors":"S. Soetrisno, Ismarwati Ismarwati, Hafi Nurinasari","doi":"10.26655/JMCHEMSCI.2021.4.5","DOIUrl":"https://doi.org/10.26655/JMCHEMSCI.2021.4.5","url":null,"abstract":"The aim of this research was to describe the effectiveness of the community development model for health promotion using WhatsApp toward old women behavior in doing an early detection of cervical cancer through the examination of visual acetic acid. The kind of this research was the mixed method and sequential strategy. The model of the mixed sequential method is a procedure of research when the researcher combines the qualitative and quantitative data by mixing in different time. The research of design used sequential explanatory; did the collection and analysis the quantitative data first, then followed by collecting the qualitative data based on the result of quantitative data. The research was conducted on December 2019 to May 2020. The research location was in Bantul District, Special Region of Yogyakarta. The partcicipants in this research were elderly women that had followed the process of quantitative research. The determination of the participants number in this research was undertaken sequentially; determining the limit of the increase until reaching the data saturation to obtain the number of participants which consisted of 15 participants, while for quantitative section, 40 participants were employed. The technique of data collection used in this research was in-depth interview, observation and study documentation. Data analysis was conducted quantitatively and qualitatively. The results indicated that from 87.5 percent of participants (35 participants), 97.5 percent did the early detection of cervical cancer. Based on the results, it was indicated that the community development model for health promotion using WhatsApp was effective in encouraging changes in the behavior of the elderly in early detection of cervical cancer through the examination of visual acetic acid in Bantul District.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"22 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77194637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Mental Health of Chemotherapy-Treated Cancer Nurses","authors":"Yosra Raziani, Sheno Raziani","doi":"10.26655/JMCHEMSCI.2021.4.6","DOIUrl":"https://doi.org/10.26655/JMCHEMSCI.2021.4.6","url":null,"abstract":"Cancer is a disease that changes the way one thinks about life, threatens to impair one's performance, and also change one's appearance. Being diagnosed with cancer causes a buzz in a person's life. Patient nurses should try to control their level of emotional distress while making vital decisions about treatment. The patient's main concerns include fears of death, dependence, malformation, disability, rejection and severance, and financial issues. Patient reactions are modulated by psychological and interpersonal factors. Medical factors include tumor location, symptoms, and course of the disease. Psychological factors include temperament, ability to adapt, ego power and the evolutionary stage of life, and the effects and meaning of cancer at that stage. Interpersonal factors are related to family and social support. Patients may experience anxiety, sadness, fear, and anger, or may become numb. Sin and the common mechanisms play a major role in it. Cognitively, patients may be aggressively seeking information, or may be confused or paralyzed or unable to concentrate. Physical complaints may increase and daily activities, appetite and sleep may be disturbed. Acute stress reactions may be severe but are usually variable and transient. When the disorder lasts for more than 10-14 days, Baciti evaluates the patient for psychiatric status.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82437025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Firdaws A. AL-Mashhadani, Shahad Abdul Rasol Albayati, S. M. Haidary
{"title":"The Protective Effect of Powdered Tart Cherry Supplements or Eating Local Iraqi Tart Cherry Fruit on Moderate to Border Level of Uric Acid and Lipid Profile in Human Serum","authors":"Firdaws A. AL-Mashhadani, Shahad Abdul Rasol Albayati, S. M. Haidary","doi":"10.26655/JMCHEMSCI.2021.4.4","DOIUrl":"https://doi.org/10.26655/JMCHEMSCI.2021.4.4","url":null,"abstract":"We aimed to compare the protective effect of short-term supplementation of a powdered tart cherry supplement (Prunuscerasus the sour cherry) and eating local tart cherry fruit in the north of Iraq, in managing hyperlipidemia and relieving the pain of gout. Four groups were recruited: Two for moderate to border level of uric acid and two for moderate to high hyperlipidemia patients; a group once dealing with300g local fresh tart cherry and the other group with 500mg of freeze dryer powder capsule of tart cherry fruits daily for six weeks. The participants were randomly assigned into a placebo or treatment group. 24-hr dietary records were required to be filled by the volunteers before taking blood, which allowed the assessment of any dietary changes. A fasting blood sampling occurred on the first day of the study (baseline). After a 6-week intervention period, the whole blood was collected for lipid profile analysis. Total cholesterol, low-density lipoprotein (LDL), and triglyceride were significantly lower in participants receiving local tart cherry fruits compared with those receiving freeze-dried tart cherry powder capsule and in the control group, a significant increase in high-density lipoprotein (HDL), along with a significant lowering of serum uric acid, especially for border level of serum uric acid patients without medication was found. All participants had a high degree of interest, mainly as the fruits existing were cheap in northern Iraq instead of its capsule that was expensive and not present in this region. We recommend local freeze dryer powder capsule be available in Iraq.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90076603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determinants of Caregiver Behaviour to the Quality of Life among Psychiatric Patients after Removal of Shackles in Klaten and Sukoharjo","authors":"A. Widodo, Arum Pratiwi","doi":"10.26655/JMCHEMSCI.2021.4.2","DOIUrl":"https://doi.org/10.26655/JMCHEMSCI.2021.4.2","url":null,"abstract":"Caregiver’s behaviour in caring for family members with mental disorders highly influenced the life quality of post-shackle psychiatric patients. This study aimed at determining the determinants of behaviour in the caregiver that affect the life quality of post-shackle patients. The study was conducted using an analytical survey with a cross-sectional study approach. Samples were taken from a population of 63 post-shackle patients and their caregivers in Klaten and Sukoharjo. All seven determinants of caregiver behaviour were analysed by concurrent regression. The independent variables were knowledge, attitudes, behavioural tendencies, subjective norms, self-efficacy, intentions, and social support from the family, while the dependent variable was the life quality of post-stock patients. Data analysis included multiple regression analysis test, t-test, F-test, and R2. The regression test revealed F obtained of 9.624 with a significance value of 0.001 (ρ <0.05) so that H0 was rejected. The determination value was 0.493. Hence, the independent variable in the model could explain 49.3% of variations of changes in the dependent variable. The study concluded that caregiver behaviour, namely the factors of knowledge, attitude, self-efficacy, and caregiver intention, partially determined the quality of life of post-shackle patients in Klaten and Sukoharjo districts.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86630892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethnobotanical Survey of Medicinal Plants Used By the Marakwet Community in Cherangani Forest, Kenya","authors":"Mourine Mutai, E. M. Njeru, R. Ntabo","doi":"10.26655/jmchemsci.2021.3.9","DOIUrl":"https://doi.org/10.26655/jmchemsci.2021.3.9","url":null,"abstract":"Since long time ago, humans have used medicinal plants. Currently, many of the contemporary drugs can be traced to plant origins. Human activities such as deforestation and farming risk the availability of medicinal plants of medical importance; therefore, there is a need to document knowledge and information on these plants. Structured questionnaires, which involved oral interviews and discussions, were used to gather information from the 35 selected herbalists. The information on every medicinal plant used in the treatment of human diseases was documented. A total of 26 medicinal plants were recorded with trees (38.5%), herbs (30.8%), shrubs (26.9%), and climbers (3.8%). The plant parts were either used singly or in combination. The mixture of leaves, roots, and barks were the most preferred combination by 77.1%, followed by barks and roots by 57.1%, and leaves and barks by 11.4%. The diseases treated were gastrointestinal ailments by 97.1%, while skin and respiratory were 80% each. Boiling was the most preferred method of preparation (58%), followed by burning to ashes (28%), boiling (12%), and raw (2%). Oral administration was the most preferred method (63%), followed by swabs (24%), and inhalation (13%). The medicinal plant's primary source was Cherangani forest (91.4%), although some herbalists had also domesticated some medicinal plants (8.6%). The study provides information on medicinal plants used by herbalists in the Marakwet community, which be used in investigating potential active compounds in the documented medicinal plants for the development of crude drugs.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75732999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Korokina, M. Pokrovskii, I. S. Kochkarova, O. N. Pokopeiko, S. Povetkin
{"title":"Investigation of Allergenic and Mutagenic Effects of Phenolic Compound, an Arignase-2 Inhibitor","authors":"L. Korokina, M. Pokrovskii, I. S. Kochkarova, O. N. Pokopeiko, S. Povetkin","doi":"10.26655/jmchemsci.2021.3.10","DOIUrl":"https://doi.org/10.26655/jmchemsci.2021.3.10","url":null,"abstract":"A big risk factor for sensitization and allergic diseases is susceptibility to animal allergens. The most significant animal allergens are derived from mammals, besides mites and cockroaches. The experiments on the allergenic properties of KUD975 were carried out on bisexual sexually mature albino guinea pigs weighing 300 ± 20 g. During the initial assessment of allergenic and mutagenic properties, the allergenic properties of KUD975 were studied by setting up an active skin anaphylaxis reaction. Mutagenicity in the test of induction of dominant lethal mutations was studied. For research, outbred male rats weighing 180-220 g KUD975 was administered intragastrically at a dose of 106 mg/kg, which corresponds to a 40-fold estimated therapeutic dose. Planting intact females at the rate of 3 heads for each male was performed weekly according to the stages of spermatogenesis. The study of the allergenic effect in the formulation of the reaction of active skin anaphylaxis in guinea pigs and mutagenicity in the test for the induction of dominant lethal mutations of the phenolic compound methyl ester (2 - ((1-hydroxy naphthalene-2-yl) thio) acetyl) -D-proline under the laboratory code KUD975 showed no signs of allergenicity and mutagenicity of compound KUD975. Given the results of this study, as well as the previously conducted study of toxicological safety, pharmacological activity, methyl ester (2 - ((1-hydroxy naphthalene-2-yl) thio) acetyl) -D-proline KUD-975 can be recommended for further study as a medicinal agent acting on arignase-2 for the treatment and prevention of a number of endothelium-associated diseases.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"213 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79485467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving Knowledge of Diabetes Mellitus Patients Using Booklet","authors":"Wachidah Yuniartika, Dwi Nur Hidayati","doi":"10.26655/jmchemsci.2021.3.4","DOIUrl":"https://doi.org/10.26655/jmchemsci.2021.3.4","url":null,"abstract":"This research aimed to determine the increase in knowledge of Diabetes Mellitus patients through a booklet. This quantitative study followed a quasi-experimental design with two groups of pretest-posttest, at Kartasura Sukoharjo community health centre in April 2019. We used the purposive sampling technique with 40 samples divided into 20 samples in the experimental group and 20 samples in the control group. The patients aged 50-65 years, registered at the Chronic Disease Management Program (prolanis) Kartasura Community Health Centre, without comorbidities participated in the study. We used a questionnaire containing 20 questions that was modified by researchers. Its validity was 0.443, and its reliability was 0.945. Wilcoxon test was used to analyse the data. The results showed that the pre-test results of the experimental group showed a mean of 9.35, post-test of 12.95, and a P-value of 0.001. The pre-test results of the control group showed a mean of 11.00, post-test of 10.90, and P value of 0.414. There was also an in-depth study of the material by dividing it into small groups and giving booklets so that respondents could remember and do it at home. As for chronic disease patients, the more often they socialize, the less burden they feel.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89271574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tanjung Anitasari Indah Kusumaningrum, Novida Rohmawaty, Hestia Selena
{"title":"Reproductive Health Information from Parents: A Dominant Factor of Voluntary Counselling and Testing (VCT) HIV Intention on Adolescents","authors":"Tanjung Anitasari Indah Kusumaningrum, Novida Rohmawaty, Hestia Selena","doi":"10.26655/jmchemsci.2021.2.8","DOIUrl":"https://doi.org/10.26655/jmchemsci.2021.2.8","url":null,"abstract":"Voluntary Counselling and Testing (VCT) is a service that is very useful to detect someone's HIV status early. It is hoped that someone who engages in risky sexual behavior can take advantage of VCT services. The purpose of this study was to analyze the relationship of sex, experiences in obtaining reproductive health information from parents, community, community leaders, access to reproductive health information through social media, participation in organizations, experiences of risk behavior with the intention of VCT in adolescents in Surakarta. This research was conducted with a cross-sectional approach in April 2019. The study population was adolescents aged 15-19 years in five sub-districts in Surakarta, Indonesia (Laweyan, Banjarsari, Serengan, Pasar Kliwon, and Jebres). The number of samples in this study was 450 adolescents who were taken with a quota sampling technique. Bivariate analysis was performed using chi-square and Fisher exact and multivariate analysis using logistic regression analysis. The results showed a relationship between getting reproductive health information from parents (p-value 0.003) and community leaders (p-value 0.027) with the intention of VCT in adolescents. The experience of getting reproductive health information from parents is the most influential factor in the intention of VCT in adolescents (OR = 0.565, CI = 0.385-0.830). Efforts are needed to provide information to adolescents about VCT services to understand that VCT is very important for follow-up care if HIV test results are reactive. Adolescents also need to be given information regarding how to increase self-efficacy to utilize VCT.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90497314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Correlation between Pain’s Level of Dysmenorrhea and Affected Activity: A Study of Young Women in Surakarta Residency","authors":"Wahyuni Wahyuni, N. Nordin, M. Mutalazimah","doi":"10.26655/JMCHEMSCI.2021.2.12","DOIUrl":"https://doi.org/10.26655/JMCHEMSCI.2021.2.12","url":null,"abstract":"Pain due to dysmenorrhea is often complained of by young women. This situation often affects daily activities, disrupts school activities, work, and social activities. The purpose of this study was to determine the correlation between the level of dysmenorrhoea pain and its results among young women in Surakarta. This study was a cross-sectional study involving 385 respondents who filled out a questionnaire about demographic data, dysmenorrhea, and its impact on activity. The most age group complaining about dysmenorrhea was 15-19 years old. The most of pain level was moderate pain, as much as 42.1%. Meanwhile, the lightest pain was mild pain, which was felt by 64.4% of respondents. All of the respondents were not married and had no sexual relations. Most body mass index was in the normal category, which is 64.9%. Of the 285 respondents, 79.2% experienced an impact on their activities due to dysmenorrhea. The most menarche age group was 12-14 years, and the most pain duration was 1-3 days. 89.9% have normal duration of menstruation. The results of statistical tests showed that the P-value","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89564265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}