Journal of Medicinal and Chemical Sciences最新文献_第8页

Geological and Geochemical Modelling of the Kudryashovskoye Field 库德里亚绍夫斯科耶油田地质地球化学模拟

Journal of Medicinal and Chemical Sciences Pub Date : 2021-04-01 DOI: 10.26655/jmchemsci.2021.2.10

G. R. Ganieva, Rustam Igorevich Sonin

{"title":"Geological and Geochemical Modelling of the Kudryashovskoye Field","authors":"G. R. Ganieva, Rustam Igorevich Sonin","doi":"10.26655/jmchemsci.2021.2.10","DOIUrl":"https://doi.org/10.26655/jmchemsci.2021.2.10","url":null,"abstract":"The practice of using chemical thermodynamics, chemical kinetics, or both to analyze chemical reactions affecting geological systems, usually with the aid of a computer, is geochemical modeling. In high-temperature geochemistry, it is used to simulate reactions occurring deep inside the Earth, in magma, for example, or to model low-temperature reactions near the Earth's surface aqueous solutions. According to the geological structure, the Kudryashovskoye field is multilayer. The placement system is selective in this field. The development of all facilities takes place using a reservoir pressure system. The well stock for drilling (throughout the field) is 42, including 28 producing wells and 14 injection wells. In 2015, 12 wells were planned to be drilled. The paper considers and analyses two options for the development approach. The first option: drilling, is planned in 2019 according to the approved layout of wells. The density of good grids is 10.6 ha/well. The second option: drilling is carried out according to the areal system with a distance of 200-250 m between the wells. The density of the wells is 8.1 ha/well. It is planned to use the technology for simultaneous-separate operation in 19 wells Modelling is carried out using the Petrel software package. After the work is done and comparative analysis, development options are proposed. The second development option is most suitable from the economic point of view and approach.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89988075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A new study biological role of hpv infection, oral contraceptive use, sex hormones and bisphenol A and increase rate cancer of cervical in libya 一项新的研究hpv感染、口服避孕药使用、性激素和双酚A与利比亚宫颈癌发病率增加的生物学作用

Journal of Medicinal and Chemical Sciences Pub Date : 2020-09-01 DOI: 10.26655/jmchemsci.2020.4.5

S. Korbag, I. Korbag

引用次数: 2

Development and validation of analytical method for simultaneous estimation of sofosbuvir and velpatasvir by RP-HPLC method in pharmaceutical dosage form 反相高效液相色谱法同时测定制剂中索非布韦和维帕他韦含量的方法建立与验证

Journal of Medicinal and Chemical Sciences Pub Date : 2020-09-01 DOI: 10.26655/jmchemsci.2020.4.2

Patel Grishma, P. Dhara, Reema Mansuri, Sapra Ritu, M. Dhananjay

{"title":"Development and validation of analytical method for simultaneous estimation of sofosbuvir and velpatasvir by RP-HPLC method in pharmaceutical dosage form","authors":"Patel Grishma, P. Dhara, Reema Mansuri, Sapra Ritu, M. Dhananjay","doi":"10.26655/jmchemsci.2020.4.2","DOIUrl":"https://doi.org/10.26655/jmchemsci.2020.4.2","url":null,"abstract":"In this work, a simple, rapid, accurate, precise, specific, and sensitive RP-HPLC method was developed and validated for the simultaneous estimation of the Sofosbuvir and Velpatasvir in bulk drug and pharmaceutical dosage form. The stationary phase used for the chromatographic separation was Hypersil BDS column C18 column (250 mm× 4.6 mm with the particle size of 5 mm) andthe mobile phase used for the separation was methanol:phosphate buffer (pH3) taken in ratio of 75:25%V/V. The flow rate was 1.0 mL/min at 30 °C. The drugs were detected at the wavelength of 260 nm. The retention time for the Sofosbuvir (SOFO) and Velpatasvir(VELP) were 3.714 and 5.263, respectively. The linearity was performed using the concentration range of 2-12 µg/mL of Sofosbuvir and 0.5-3 µg/mL of Velpatasvir. The correlation coefficient was found to be 0.999 and 0.999, respectively. The % purity of the Sofosbuvir and Velpatasvir was found to be 99.01% and 99.25%, respectively. The proposed method was validated for specificity, linearity, precision, robustness and accuracy were within the range of acceptance limit according to ICH Q2 (B) guidelines and the developed method can be employed for the routine quality control analysis in the bulk and combined pharmaceutical dosage form of Sofosbuvir and Velpatasvir.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87881513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Role of using Satellite at Home on Intimacy and Marital Satisfaction of Couples in Qom 库姆地区家庭使用卫星对夫妻亲密关系和婚姻满意度的影响研究

Journal of Medicinal and Chemical Sciences Pub Date : 2020-09-01 DOI: 10.26655/jmchemsci.2020.4.8

A. Massoumi

{"title":"Investigating the Role of using Satellite at Home on Intimacy and Marital Satisfaction of Couples in Qom","authors":"A. Massoumi","doi":"10.26655/jmchemsci.2020.4.8","DOIUrl":"https://doi.org/10.26655/jmchemsci.2020.4.8","url":null,"abstract":"Among the various and modern media, satellite can be mentioned as one of the most popular media all over the world. Satellite is one of the most influential media in the present age, which like other media and means of communication is mainly the product of the West. Some satellite programs and movies contain content in which adherence to family and moral values seems ridiculous and vulgar, as opposed to having free sex, daring sex, and questioning the importance and value of marriage. Is considered to be the result of a free-thinking and progressive view of life and emotional relationships. Asking questions and raising repeated doubts about the views of people who have not been enslaved or are living together, and in return providing views and answering skeptical questions to convince the audience that times have changed and people should not stick. On the other hand, the family as a social institution has always been considered by the legislator and several laws have been enacted in relation to this institution. Apart from the family laws, he also has special rights in terms of religion, morality and custom. These include strengthening the foundations of the family, strengthening the family, raising children, good morals and good company, healthy sexual relations and the emotional and intimate atmosphere of the family.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"220 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77010681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical screening for codeine and tramadol in urine of anonymous students attending university sick bays 在大学医务室匿名学生尿液中可待因和曲马多的化学筛选

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/jmchemsci.2020.3.2

R. Sha’Ato, A. Itodo, Atumeyi Anthony Ugbedeojo

引用次数: 0

Solar light photo-catalyzed condensation of aldones with 4-phenylthiosemicarbazide, a green chemistry approach 太阳能光催化醛酮与4-苯基硫脲的缩合反应，一种绿色化学方法

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/JMCHEMSCI.2020.3.4

Steeve M. Adjibodé, Urbain C. Kasséhin, S. Médégan, J. Quetin-Leclercq, F. Gbaguidi, J. Poupaert

引用次数: 0

An overview on the effects of power frequency electromagnetic field exposure on the female reproduction system, pregnancy outcome and fetal development 工频电磁场暴露对女性生殖系统、妊娠结局及胎儿发育的影响综述

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/jmchemsci.2020.1.8

Elham Mansuori, A. Alihemmati, A. Mesbahi

{"title":"An overview on the effects of power frequency electromagnetic field exposure on the female reproduction system, pregnancy outcome and fetal development","authors":"Elham Mansuori, A. Alihemmati, A. Mesbahi","doi":"10.26655/jmchemsci.2020.1.8","DOIUrl":"https://doi.org/10.26655/jmchemsci.2020.1.8","url":null,"abstract":"This article presents a review of the published scientific studies on the potential adverse effects of power frequency electromagnetic field (50-60 Hz) from domestic and occupational sources and electric transmission lines on female reproduction system and pregnancy outcome. In this review, publications in English were searched in the ISI Web of Knowledge, PubMed databases and GoogleScholar from January 2000 to December 2017 articles. For ascertaining the reliability of study, data were extracted independently and in duplicate by two investigators. According to some of the conducted studies, environmental exposure to power frequency EMF (electromagnetic field) exposure was found to adversely affect sex hormones, female genital system, embryonic development, pregnancy outcome and fetal and offspring development, while other studies reported no significant effect of power frequency EMF exposure on reproductive parameters and embryonic and fetal development. Overall, the results were not convergent and there was controversy regarding the findings. However, it can be concluded that a part of controversy can be attributed to differences in field strength and exposure time, the experiment condition in terms of in vivo and in vitro which had a significant impact on the observed results.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85134904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Salicylic Acid as a Bio-based and Natural Brønsted Acid Catalyst Promoted Green and Solvent-free Synthesis of Various Xanthene Derivatives 水杨酸作为生物基天然硼酸催化剂促进了多种杂蒽衍生物的绿色无溶剂合成

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/jmchemsci.2020.3.8

F. Mohamadpour, Mansoor Feilizadeh

引用次数: 3

Nanohybrid based on layered zinc hydroxide with salicylic acid drug: Investigation of the structure and controlled release properties 水杨酸类药物层状氢氧化锌纳米杂化物的结构与控释性能研究

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/jmchemsci.2020.3.5

H. Nabipour, Yuan Hu

引用次数: 3

Determination of tartrazine in some food and medicine samples after solid phase extraction 固相萃取法测定食品和药品中酒黄石的含量

Journal of Medicinal and Chemical Sciences Pub Date : 2020-06-01 DOI: 10.26655/jmchemsci.2020.3.10

Nazan Sayar, A. Karatepe

{"title":"Determination of tartrazine in some food and medicine samples after solid phase extraction","authors":"Nazan Sayar, A. Karatepe","doi":"10.26655/jmchemsci.2020.3.10","DOIUrl":"https://doi.org/10.26655/jmchemsci.2020.3.10","url":null,"abstract":"Food dyes are one of the most widely used additives in commercial food products such as beverages, candies, pharmaceuticals, and cosmetics. Despite the laws and regulations which aim to limit the synthetic colourant usage due to their pathogenic effects, they are widely used. Therefore, analyzing these dyes become very important for human health. Tartrazine is one of the commonly used synthetic food dyes and so the development of a new, simple, and accurate separation, preconcentration, and spectrophotometric determination of tartrazine (E 102) was the aim of this work. The method was based on solid-phase extraction by using Diaion SP-207 resin and determination with UV Spectrophotometer. Analytical parameters affecting the recoveries of tartrazine were investigated to find the optimal conditions. The retained tartrazine was removed from the column by 10 mL of 0.01 M HCl in acetone. The recovery values were found as >95%. By this new method, tartrazine contents of various food and medicine samples were determined successfully. TThe recoveries of understudy analytes were found in the range of 93–98%, while the detection limits were calculated in the range of 0.3–2.0 μg L−1.he detection limit was found as 3.52 μg/L. Calibration standards used in the experiments were in the range of 10-7 -1x10-5 mol L-1 with a correlation coefficient of 0.999.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79478693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1