Journal of Multidisciplinary Healthcare最新文献

{"title":"A Bibliometric Analysis of Acupuncture Treatment of Postoperative Complications from 2003 to 2023.","authors":"Daocheng Zhu, Wei Xu, Wenguo Ye, Yuexia Jiang, Lin Jiao, Rixin Chen","doi":"10.2147/JMDH.S528696","DOIUrl":"10.2147/JMDH.S528696","url":null,"abstract":"<p><strong>Background: </strong>Postoperative complications refer to some related clinical symptoms that occur after surgery, which can affect7 the patient's recovery. Acupuncture has a good effects on postoperative complications, which can accelerate postoperative recovery. Currently, there are many literature studies in this field. However, there has been no quantitative analysis of these literature. Therefore, in this study, the bibliometric method was adopted to analyze the relevant literature, thereby exploring the research hotspots and trends in this field.</p><p><strong>Methods: </strong>Through the web of science core database, we collected the relevant literature on the acupuncture treatment of postoperative complications from 2003 to 2023, used citespace software to analyze the author, publishing institution, country, keywords, references, cited journals and other information of these literature, and analyzed its research hotspots and research trends through a visual view.</p><p><strong>Results: </strong>A total of 213 articles were obtained, and the annual publication volume overall is on the rise, especially in recent years when the publication volume has surged. The field with the highest number of publications is Integrative Complementary Medicine. The most cited journal is Evidence-Based Complementary and Alternative Medicine. The country with the highest number of publications is China, and the institution with the highest number of publications is Capital Medical University. The author with the highest number of publications is Zhu, Junchao. The most central cited author is LEE A. The articles with the highest frequency and centrality of cited references are published by Liu, Y. H. The most frequently studied keywords are acupuncture.</p><p><strong>Conclusion: </strong>This study systematically analyzes the current research status and hotspots of acupuncture treatment for postoperative complications in the past 20 years, which can help researchers grasp the current research direction and provide reference basis for further research.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3269-3287"},"PeriodicalIF":2.7,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12154538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Bibliometric Analysis of Cardiovascular Disease Risk in Obesity (2014-2024).","authors":"Hang Yang, Tao Zhang, Dongyang Wang, Edmund Loi, Qixiang Geng, Baoling Wu, Xi Wang, Rongjiang Cai","doi":"10.2147/JMDH.S504022","DOIUrl":"10.2147/JMDH.S504022","url":null,"abstract":"<p><strong>Background: </strong>Obesity, as a global chronic disease, is causing an increasing risk of cardiovascular disease. This study used bibliometrics to synthesize and analyze publications related to obesity and cardiovascular risk from 2014 to 2024. It aimed to clarify the current status of research, predict future trends, and provide a scientific basis for prevention and treatment.</p><p><strong>Methods: </strong>In this study, we used bibliometrics online analysis platform, Citespace (version 6.3.R1, LLR algorithm) and VOSviewer (version 1.6.20) software to analyze the co-occurrence network analysis of publications related to cardiovascular risk of obesity in worldwide for countries, institutions, authors, and journals from January 2014 to September 2024, and keyword co-occurrence, clustering, and burst analysis were performed to reveal research trends and hotspots.</p><p><strong>Results: </strong>A total of 1492 articles related to cardiovascular risk in obesity were selected for this study, and in terms of the number of publications showed a steady increase over time. Based on keyword clustering analysis, the field can be summarized into two research themes: the field of the relationship between health indicators such as BMI, waist circumference, cardiovascular disease, and the field of metabolism and obesity-related issues. According to the keyword burst analysis, the keywords cholesterol, oxidative stress, non-alcoholic fatty liver disease, and ratio to height became prominent and will be the main research hotspots in the future.</p><p><strong>Conclusion: </strong>In recent years, there has been a rapid increase in cardiovascular risk research in obese patients. This article reveals the remarkable progress and dynamic trends in this field, providing strong support for exploring new directions, as well as laying a data foundation for public health policy development and interdisciplinary collaboration. Future research should prioritize focusing on mechanism exploration and clinical application of novel drugs to promote health improvement.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3233-3255"},"PeriodicalIF":2.7,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice of Medical Staff Towards Metabolic Syndrome in Schizophrenia in Chinese Hospitals: A Cross-Sectional Study.","authors":"Yuejia Wang, Xuefen Yu, Haiqin Chen, Chunxia Tang, Na Zhang","doi":"10.2147/JMDH.S503664","DOIUrl":"10.2147/JMDH.S503664","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the knowledge, attitude, and practice (KAP) of medical staff regarding metabolic syndrome in schizophrenia in Chinese hospitals, emphasizing implications for improving clinical management.</p><p><strong>Methods: </strong>This multicenter, cross-sectional study enrolled medical staff in 5 hospitals between March 2024 and April 2024. A self-administered questionnaire was developed to collect the demographic information and KAP scores of the participants.</p><p><strong>Results: </strong>A total of 359 valid questionnaires were analyzed, with 280 respondents (77.99%) being female and 298 (83.01%) employed in public tertiary hospitals. Mean scores for knowledge, attitude, and practice were 30.93±7.45, 28.81±3.60, and 22.50±5.11, respectively. The proportion of participants achieving good levels of knowledge, attitude, and practice (defined as scores ≥60% of the maximum score) was 75.77%, 99.72%, and 88.58%, respectively. Multivariate logistic regression identified several factors independently associated with practice: higher knowledge scores (OR = 1.16), positive attitude scores (OR = 1.09), being female (OR = 2.64), having ≥16 years of experience (OR = 3.24), and previous experience in managing patients with metabolic syndrome in schizophrenia (OR = 0.50). Approximately 64.9% of participants had experience treating patients with schizophrenia and metabolic syndrome, and this experience was significantly associated with higher practice scores. Structural equation model analysis revealed that knowledge influenced attitude (β = 0.10), attitude influenced practice (β = 0.82), and knowledge directly influenced practice (β = 0.50).</p><p><strong>Conclusion: </strong>Medical staff possess adequate knowledge, positive attitude, and proactive practice concerning metabolic syndrome in schizophrenia. Although the overall level of KAP was good, there is still room for further improvement. The findings suggest targeted interventions, such as continuous education programs and training tailored for Chinese medical staff, could enhance their proactive practices in managing metabolic syndrome in schizophrenia patients.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3257-3268"},"PeriodicalIF":2.7,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses.","authors":"Shuang Chen, Shihao Sun, Zihan Zhou, Zhaokai Zhou, Ran Zhang, Wenyan Song, Hang Xin, Qingling Yang, Shanjun Dai, Kai Huang, Wenbin Niu, Hao Shi, Yihong Guo","doi":"10.2147/JMDH.S524949","DOIUrl":"10.2147/JMDH.S524949","url":null,"abstract":"<p><strong>Background: </strong>Accumulative prior studies have demonstrated that immune inflammation profoundly influences reproductive disorders of mesodermal origin. However, little is known about the causal relationship between immune factors and diseases of the reproductive system.</p><p><strong>Methods: </strong>Thorough two-sample Mendelian randomization (MR) analyses were conducted to determine the causal effects of 731 immune traits on reproductive ill-health, including abnormal spermatozoa (AS), polycystic ovary syndrome (PCOS), and spontaneous abortion (SA). Causal links were decrypted using genome-wide association study (GWAS) data. Sensitivity analyses were performed to assess the strength, heterogeneity, and horizontal pleiotropy of the results.</p><p><strong>Results: </strong>For AS, 34 causal relationships were identified, with BAFF-R, CD20, and CD27 in the B-cell panel having protective effects against AS. A crucial causative connection between <i>CD11c+ CD62L- monocyte%monocyte</i> (cDC panel) and AS pathogenesis was also revealed. For PCOS, 40 causal effects were established, with CD20, CD24, and CD27 in the B-cell panel playing different roles in PCOS. <i>CD4 on CM CD4+</i> (maturation stages of the T-cell panel) significantly increased the risk of PCOS. For SA, 33 causative associations were determined, and a protective effect of <i>CCR2 (C-C chemokine receptor type 2) on CD14+ CD16+ monocytes</i> (monocyte panel) in SA was particularly noted. The diverse functions of the CD28, CD39, and CD25 molecules in the Treg cell panel in SA were also observed.</p><p><strong>Conclusion: </strong>This study comprehensively evaluated the causal impact of immune traits on reproductive illnesses, stressing the complex and important role of immunogenic factors in pathogenesis and highlighting a novel direction for clinical work.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3219-3232"},"PeriodicalIF":2.7,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Round-Sharp Needle for Limb Spasms After a Stroke: Study Protocol for a Randomized Controlled Trial.","authors":"Hongkun Ye, Jiahui Liu, Hongmei Cheng, Yu He, Chongrui Li, Yahan Gao, Xinyin Xu","doi":"10.2147/JMDH.S512206","DOIUrl":"10.2147/JMDH.S512206","url":null,"abstract":"<p><strong>Objective: </strong>Stroke can cause limb spasticity, and numerous clinical studies have demonstrated that acupuncture is an effective treatment for this condition. The round-sharp needle, a type of acupuncture needle, has been reported to shorten treatment durations and reduce the number of clinic visits compared to traditional filiform needles, the conventional acupuncture. However, clinical trial research on its efficacy remains limited. Therefore, this clinical trial is designed to investigate the short-term effects and safety of round-sharp needle therapy in treating post-stroke limb spasticity.</p><p><strong>Methods and analysis: </strong>This research protocol outlines a randomized, single-blind, prospective, single-center pilot clinical trial to be conducted at Hubei Provincial Hospital of Traditional Chinese Medicine, scheduled to commence after completion of clinical trial registration. After the recruitment phase, eligible patients meeting the inclusion criteria will be randomly assigned to one of two groups: the round-sharp needle group (3 times per week) or the filiform needle group (5 times per week). The treatment will last for two weeks, with evaluation criteria including surface electromyography (sEMG), the Modified Ashworth Scale (MAS), the Fugl-Meyer Assessment (FMA), the Modified Barthel Index (MBI), and a safety assessment of acupuncture.</p><p><strong>Conclusion: </strong>This clinical trial investigates the safety and efficacy of using round-sharp needles to treat post-stroke limb spasticity, with the results expected to provide further evidence for the future clinical application of this therapy.</p><p><strong>Trial registration: </strong>Chinese Clinical Trial Registry (ChiCTR), ID: ChiCTR2400087907. Registered on 7 August, 2024.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3179-3189"},"PeriodicalIF":2.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Neonatal Hypothermia Prediction Model for In-Hospital Transport Using Machine Learning Algorithms: A Single-Center Retrospective Study.","authors":"Wenyan Zhang, Xiaoying Gu, Chunjie Gu, Lili Yao, You Zhang, Ke Wang","doi":"10.2147/JMDH.S517499","DOIUrl":"10.2147/JMDH.S517499","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to predict hypothermia during neonatal in-hospital transport using machine learning techniques, identify risk factors, rank their importance, and visualize the results, allowing healthcare providers to rapidly assess the probability of hypothermia risk during transport.</p><p><strong>Methods: </strong>Clinical data of 9,060 neonates transported within a tertiary maternity hospital in Shanghai between January 2023 and June 2024 were collected, including maternal and neonatal data. Variables were selected using LASSO regression. Neonates were categorized into hypothermia and normal temperature groups based on their body temperature during transport, with 6:2:2 ratio for training, test and validation datasets. Six machine learning algorithms-Decision Tree (DT), Random Forest (RF), eXtreme Gradient Boosting (XGBoost), Support Vector Machine (SVM), Artificial Neural Network (ANN), and Naive Bayes (NB)-were used to develop predictive models. The effectiveness was evaluated using area under the ROC curve (AUC), along with F1 score, accuracy, sensitivity, specificity, and Hosmer-Lemeshow calibration tests with Brier scores. The best-performing model was further analyzed for risk factors using SHAP plots.</p><p><strong>Results: </strong>Among the neonates, 5,072 (55.98%) experienced hypothermia during transport. Ten risk factors were identified through univariate analysis and LASSO regression, including gestational age, weight, and immediate postnatal contact. The RF model demonstrated the best overall performance, achieving a training set AUC of 0.994 and an accuracy of 0.957, while the test set AUC and accuracy were 0.962 and 0.889, respectively.</p><p><strong>Conclusion: </strong>Hypothermia incidence during neonatal in-hospital transport is relatively high. The RF-based prediction model demonstrated strong predictive and generalization capabilities, providing actionable guidance for early identification of neonates at risk of hypothermia during transport.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3205-3217"},"PeriodicalIF":2.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Updated Scoping Review of Factors Associated with Length of Stay in Emergency Department.","authors":"Kurhayati Kurhayati, Etika Emaliyawati, Yanny Trisyani","doi":"10.2147/JMDH.S525451","DOIUrl":"10.2147/JMDH.S525451","url":null,"abstract":"<p><strong>Background: </strong>The Emergency Department (ED) is important to the hospital healthcare system. However, increasing patient visits to the ED have increased the length of stay (LOS), which contributes to overcrowding, resource constraints, and decreased quality of care. Factors affecting LOS are complex and involve patient characteristics, hospital operations, and health system policies.</p><p><strong>Purpose: </strong>This review aimed to explore the factors influencing ED LOS.</p><p><strong>Methods: </strong>This study employed a scoping review with the PRISMA-ScR approach, analyzing articles from PubMed, Scopus, Taylor & Francis, and EBSCOhost databases published between 2022 and 2025. The keywords used were Emergency department patients OR ED patients OR Hospital admissions OR Emergency visits AND Length of stay OR hospital stay AND Predictor OR Factor. The quality appraisal of the articles was assessed using the Joanna Briggs Institute critical evaluation tool. Data were analyzed using descriptive qualitative and thematic analysis.</p><p><strong>Results: </strong>Factors influencing LOS in the ED were categorized into five main categories: (1) Patient characteristics (advanced age, male gender, comorbidities, and specific clinical conditions such as sepsis and blood diseases); (2) Time and environmental factors (nighttime, weekend, and winter visits); (3) Hospital and health system factors (hospital type, bed capacity, insurance status, and triage severity); (4) Diagnostic and treatment processes (waiting times for radiology and laboratory examinations, delays in specialist consultations, and limited inpatient beds); and (5) Patient arrival mode (arriving by ambulance or referred from another hospital).</p><p><strong>Conclusion: </strong>Longer LOS in the ED is influenced by various multidimensional factors that interact with each other. To reduce patient stays in the ED, efforts to optimize triage, improve diagnostic efficiency, and strengthen coordination between hospital units are needed. Evidence-based strategies such as digitizing medical records and predictive analytics can help improve service efficiency and reduce ED congestion.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3191-3203"},"PeriodicalIF":2.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Credibility of Public Health Campaigns and Its Impact on Infection Control Behaviors: Mediating Roles of Health Literacy and Motivation.","authors":"Khalid Abdullah Alotaibi","doi":"10.2147/JMDH.S520357","DOIUrl":"10.2147/JMDH.S520357","url":null,"abstract":"<p><strong>Background: </strong>Public health campaigns are vital in promoting infection control behaviors, particularly during health crises. The effectiveness of such campaigns can be influenced by various factors, including the perceived credibility of the messages, health literacy, and motivation to adopt health behaviors. Understanding the relationships between these factors is crucial for enhancing the impact of health campaigns. This study aimed to examine the effect of the perceived credibility of public health campaigns on infection control behaviors, with health literacy and motivation serving as mediators in Riyadh, Saudi Arabia.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted between November and December 2024 with 393 participants in Riyadh. Structural equation modeling (SEM) and path analysis were used to assess perceived credibility's direct and indirect effects on infection control behaviors through health literacy and motivation while controlling for age, gender, and education.</p><p><strong>Results: </strong>The results showed that perceived credibility had a significant direct effect on adherence to preventive behaviors (β = 0.44, p < 0.001) and motivation significantly mediated this relationship (indirect effect: β = 0.08, p < 0.01). However, no significant indirect effect was found through health literacy (indirect effect: β = 0.006, p > 0.05).</p><p><strong>Conclusion: </strong>This study emphasizes the critical roles of perceived credibility and motivation in driving infection control behaviors. The findings suggested that public health campaigns should focus on enhancing the credibility of health messages and fostering motivation to improve adherence to preventive measures. These insights have practical implications for designing more effective public health strategies in regions like Riyadh, Saudi Arabia.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3153-3163"},"PeriodicalIF":2.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staged CBI for Reducing Anxiety and Depression in Lung Cancer Patients Undergoing Chemotherapy: A Retrospective Cohort Analysis.","authors":"Lei Chen, Yongxia Sun, Huanhuan Yu, Min Sun","doi":"10.2147/JMDH.S506310","DOIUrl":"10.2147/JMDH.S506310","url":null,"abstract":"<p><strong>Background: </strong>The success rate of Staged cognitive behavioral intervention (CBI) in reducing emotional discomfort and enhancing the life-quality of patients undergoing chemotherapy for lung cancer was assessed retrospectively in this study.</p><p><strong>Objective: </strong>The records of 55 affected role received/receiving chemotherapy for lung cancer were examined for Staged CBI.</p><p><strong>Methods: </strong>In this study, patients' life related information's were obtained through demographic questionnaires. The 36-Item Short Form Survey (SF-36) was included as a single question that indicates subjective shifts in well-being. The Functional Assessment of Cancer Therapy-General (FACT-G) and the Lung Cancer Symptom Scale (LCSS) were designed as measuring scales for quality of life (QoL). Cohen's d indexes were measured to analyze the group's effectual size. The follow-up data were collected 6-8 weeks after the Staged CBI sessions.</p><p><strong>Results: </strong>The SF-36 showed that effect size was large for most of the domains (Cohen's d > 1.2) and post CBI intervention was not significant except physical function. The FACT-G survey revealed that improvements were significant for observation group vs control for physical well-being (p = 0.004), social well-being (p = 0.007), emotional well-being (p = 0.008), and functional well-being (p = 0.045). The LCSS survey showed clinically marked changes for activity level, daily routine and social activities from 43.86 ± 20.16 to 71.29 ± 25.42, 45.36 ± 32.65 to 72.36 ± 26.78, and 35.36 ± 31.07 to 77.77 ± 28.58, respectively (P > 0.001). The resulting outcomes were significant in getting better the overall Global QoL of the patients. Besides these, the symptoms burden was also promisingly reduced.</p><p><strong>Conclusion: </strong>The function of CBI in lung cancer chemotherapy patients has not yet been examined retrospectively. This study investigated how CBI affects the treatment of mental health issues and enhances patients' treatment compliance and quality of life.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3165-3177"},"PeriodicalIF":2.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric Analysis of microRNA: A Comprehensive Evaluation of Its Contribution to Acute Coronary Syndromes.","authors":"Yuqian Gao, Tianli Li, Xiaohong Mu, Xiaoxia Ren, Jing Wang, Jiasai Fan, Haiyan Zhu, Xian Wang","doi":"10.2147/JMDH.S525150","DOIUrl":"10.2147/JMDH.S525150","url":null,"abstract":"<p><strong>Objective: </strong>This study employs bibliometric analysis to map the evolution, identify emerging trends, and evaluate key research themes in microRNA (miRNA) research related to Acute Coronary Syndromes (ACS). By analyzing global publications, we aim to highlight hotspots and translational directions for advancing miRNA applications in ACS diagnosis and therapy.</p><p><strong>Materials and methods: </strong>Articles on miRNA and ACS published between 2007 and 2023 were retrieved from the Web of Science Core Collection. Data from 1,244 eligible studies were analyzed using CiteSpace and VOSviewer to assess contributions by countries, institutions, authors, journals, and keywords. Visualization tools mapped collaboration networks, co-citation patterns, and keyword trends.</p><p><strong>Results: </strong>China contributed 60% of publications, followed by the United States (12.86%). Harbin Medical University was the most productive institution, while Thum Thomas emerged as the leading researcher. Key research areas included miRNA biomarkers for ACS diagnosis, therapeutic targets for ischemia-reperfusion injury, extracellular vesicles in cardiac repair, and mechanistic studies on apoptosis, autophagy, and inflammation. Emerging frontiers encompassed ventricular remodeling post-AMI, oxidative stress, and clinical translation of miRNA-based strategies.</p><p><strong>Conclusion: </strong>This study provides the first comprehensive bibliometric overview of miRNA research in ACS, revealing sustained growth and interdisciplinary potential. Findings underscore China's dominance in output and the need for enhanced international collaboration to bridge gaps between basic research and clinical applications. Prioritizing extracellular vesicle-mediated therapies, optimizing miRNA delivery systems, and validating biomarkers in multicenter trials are critical for future advancements.</p>","PeriodicalId":16357,"journal":{"name":"Journal of Multidisciplinary Healthcare","volume":"18 ","pages":"3121-3137"},"PeriodicalIF":2.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}