{"title":"Reflections on AI use declarations in JME manuscripts.","authors":"Joshua Parker","doi":"10.1136/jme-2026-112675","DOIUrl":"10.1136/jme-2026-112675","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":"721-722"},"PeriodicalIF":4.4,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jordan Sibeoni, Laurence Verneuil, Anne Revah-Levy
{"title":"Giving voice without guardrails: lived experience and the ethics of epistemic mediation in public health.","authors":"Jordan Sibeoni, Laurence Verneuil, Anne Revah-Levy","doi":"10.1136/jme-2026-111831","DOIUrl":"https://doi.org/10.1136/jme-2026-111831","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From principles to practice: an Implementation Decision-Tool for Ethical AI in clinical governance.","authors":"Hazem Zohny, Ilina Singh, Julian Savulescu","doi":"10.1136/jme-2025-111546","DOIUrl":"https://doi.org/10.1136/jme-2025-111546","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structural realities and personal impact: how ethics teaching can prepare students for early clinical practice.","authors":"Simon Walker, Sinead Donnelly, John McMillan","doi":"10.1136/jme-2026-112130","DOIUrl":"https://doi.org/10.1136/jme-2026-112130","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149228041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Staging disease without illness: ethical issues of the Huntington's Disease Integrated Staging System (HD-ISS).","authors":"Max J Rensink, Bjørn M Hofmann","doi":"10.1136/jme-2025-111586","DOIUrl":"https://doi.org/10.1136/jme-2025-111586","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ethics of opportunistic genomic screening in paediatrics: rethinking the risk-benefit ratio.","authors":"Emily Wheeler, Wayne Shelton, Gina Geis","doi":"10.1136/jme-2026-111946","DOIUrl":"https://doi.org/10.1136/jme-2026-111946","url":null,"abstract":"<p><p>Genome-wide sequencing (GWS) has become an important tool in paediatric medicine, but it may uncover secondary findings (SFs) through opportunistic screening. The disclosure of adult-onset SFs in children, who cannot consent, raises ethical concerns regarding potential psychosocial harm and future autonomy. This paper examines whether parents should have the option to consent to opportunistic screening for actionable adult-onset conditions in their young children. Although there is consensus on disclosing actionable childhood-onset conditions, international guidelines remain divided on the return of adult-onset findings in paediatric populations. Drawing on existing literature, this paper argues for greater consensus around a risk-benefit framework centred on medical actionability. Emerging evidence suggests that the psychological harms associated with predictive testing may be less severe than previously assumed, while actionable findings may provide meaningful benefits to both the child and family. This paper further argues that upholding parental authority through shared decision-making and the concept of family benefit further supports offering parents the option to receive actionable adult-onset findings. In contrast, the disclosure of non-actionable adult-onset conditions is more difficult to justify given the absence of meaningful clinical benefit. In the absence of clear evidence of harm, a more family-centred approach that incorporates pretest counselling and ongoing support offers a practical framework for moving towards greater consensus on this long-debated issue.</p>","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MacIntyrean bioethics: reappraisal and outline of a research programme.","authors":"Morten Magelssen, Søren Holm, Eilev Hegstad, Skylar Christoffersen","doi":"10.1136/jme-2026-112142","DOIUrl":"https://doi.org/10.1136/jme-2026-112142","url":null,"abstract":"<p><p>Alasdair MacIntyre's (1929-2025) work in moral philosophy was wide-ranging, erudite and controversial. Following his death in 2025, it is appropriate to reappraise the relevance of his work to bioethics. MacIntyre's analysis may helpfully be divided into his 'critical project', which criticises modern moral philosophy and reveals and explains its shortcomings, several of which arguably affect bioethics; and his 'constructive project', which sets out MacIntyre's version of neo-Aristotelian virtue ethics. We summarise these 'projects' and how they have been used within bioethics. Our claim is that there is still significant untapped potential for work in medical ethics/bioethics inspired by MacIntyre. We propose further uses of MacIntyre under the five headings critical, diagnostic, revisionist, normative and hermeneutic. The article ends with a brief reflection on the merits and limits of a MacIntyrean bioethics.</p>","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beochaoineadh: grieving but not bereaved.","authors":"Martha Finnegan","doi":"10.1136/jme-2024-110610","DOIUrl":"10.1136/jme-2024-110610","url":null,"abstract":"","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":"714-715"},"PeriodicalIF":4.4,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena Carley, Kate Sahan, Helen Hanson, Katie Snape, Sarah Westbury, Michael J Parker, Anneke M Lucassen
{"title":"Germline genomic testing to assess the suitability of stem cell donors in the treatment of haematological malignancy: clinical ethics commentary.","authors":"Helena Carley, Kate Sahan, Helen Hanson, Katie Snape, Sarah Westbury, Michael J Parker, Anneke M Lucassen","doi":"10.1136/jme-2025-111111","DOIUrl":"10.1136/jme-2025-111111","url":null,"abstract":"<p><p>The increasing integration of genomic medicine into routine medical care brings to light issues of complexity and uncertainty in the interpretation of genetic variation.We describe a fictional case study based on our experiences in the haematological malignancy setting to illustrate the complexities in using genomic testing to evaluate the suitability of relatives to act as stem cell donors. In particular, we demonstrate the ethical issues arising following the identification of a germline variant of uncertain significance (VUS) in a gene associated with inherited cancer susceptibility in a potential recipient. We discuss the factors that need to be considered, such as how this might influence donor selection, the potential for donor-derived leukaemia and the issues of offering testing to other family members.Popular discourse suggests genomics can offer clarity and transformation in healthcare. This case highlights the ethically complex nature of decision-making in genetic medicine due to the familial aspects of genomic information, the uncertain nature of many genomic results and how changes in the use of genomic information in clinical practice can call for urgent decision-making. This highlights the need for increased interdisciplinary working which takes into account the factors driving decisions for each specialty and recommends access to independent ethics support for members of the multidisciplinary team.</p>","PeriodicalId":16317,"journal":{"name":"Journal of Medical Ethics","volume":" ","pages":"672-677"},"PeriodicalIF":4.4,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7619150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145564235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}