Journal of King Saud University - Science最新文献

{"title":"Inhibitory effects of cuminaldehyde on human liver cytochrome P450 enzymes","authors":"Naif Fahad M. Alharbi,&nbsp;Abdul Ahad,&nbsp;Yousef A. Bin Jardan,&nbsp;Fahad I. Al-Jenoobi","doi":"10.1016/j.jksus.2024.103467","DOIUrl":"10.1016/j.jksus.2024.103467","url":null,"abstract":"<div><div>This work explored the influence of cuminaldehyde on the metabolic activity of four primary human cytochrome P450 (CYP) enzymes. Human liver microsomes (HLM) with and without cuminaldehyde were incubated with specific substrates of different CYP enzymes. The influence of cuminaldehyde on “CYP1A2, CYP2C9, CYP2D6 and CYP3A4” activities was examined. The formation of specific metabolites was analyzed by HPLC analytical methods. It was observed that cuminaldehyde appears to have a negligible influence on CYP1A2 activity. However, CYP2C9 activity was significantly and potently inhibited by cuminaldehyde at all investigated concentrations. It was found that cuminaldehyde (1 µM) inhibited the most CYP2C9 enzyme activity with 64.87 % inhibition followed by CYP3A4 (38.90 %), CYP2D6 (25.76 %) and CYP1A2 (4.99 %). Inhibition of both CYP2D6 and CYP3A4 enzyme activity was observed in response to cuminaldehyde concentrations. Findings of the current investigation indicate that herb-drug interactions are very possible when cuminaldehyde is concurrently taken with medicines predominantly metabolized by CYP2C9 and CYP3A4. Cuminaldehyde should be tested further to examine how it affects CYP2C9 and CYP3A4-metabolized drugs.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103467"},"PeriodicalIF":3.7,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Antibiofilm efficacy of novel biogenic silver nanoparticles from Terminalia catappa against food-borne Listeria monocytogenes ATCC 15,313 and mechanisms investigation in-vivo and in-vitro” [J. King Saud Univ. – Sci. 34(5) (2022) 102083]","authors":"Lakshmanan Muthulakshmi ,&nbsp;Kannan Suganya ,&nbsp;Maruthamuthu Murugan ,&nbsp;Jamespandi Annaraj ,&nbsp;Veeramuthu Duraipandiyan ,&nbsp;Dunia A. Al Farraj ,&nbsp;Mohamed S. Elshikh ,&nbsp;Annie Juliet ,&nbsp;Mukesh Pasupuleti ,&nbsp;Jesu Arockiaraj","doi":"10.1016/j.jksus.2024.103459","DOIUrl":"10.1016/j.jksus.2024.103459","url":null,"abstract":"","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103459"},"PeriodicalIF":3.7,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142319142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Neuroprotective and antioxidant capability of RW20 peptide from histone acetyltransferases caused by oxidative stress-induced neurotoxicity in in vivo zebrafish larval model” [J. King Saud Univ. – Sci. 34(3) (2022) 101861]","authors":"Nagaram Prabha ,&nbsp;Ajay Guru ,&nbsp;Ramasamy Harikrishnan ,&nbsp;Mansour K. Gatasheh ,&nbsp;Ashraf Atef Hatamleh ,&nbsp;Annie Juliet ,&nbsp;Jesu Arockiaraj","doi":"10.1016/j.jksus.2024.103458","DOIUrl":"10.1016/j.jksus.2024.103458","url":null,"abstract":"","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103458"},"PeriodicalIF":3.7,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142318924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental and Statistical approach to understand the adsorption properties of hazardous Cr(VI) on Al2O3@TiFe2O4 nanocomposite: An efficient adsorbent for water treatment","authors":"Salman Latif ,&nbsp;Kaseb D. Alanazi ,&nbsp;Basmah H. Alshammari ,&nbsp;Amir Al‑Ahmed ,&nbsp;Abdulaziz M. Alanazi","doi":"10.1016/j.jksus.2024.103455","DOIUrl":"10.1016/j.jksus.2024.103455","url":null,"abstract":"<div><div>Doping of metal oxide with other suitable component can enhance its structural and characteristic properties. At the end it improves its overall application performances. This study introduces the novel synthesis of Al₂O₃@TiFe₂O₄ nanocomposite via co-precipitation for Cr(VI) removal. Unlike previous studies, this unique material exhibits superior adsorption capacity and efficiency. The comparative analysis with existing adsorbents underscores its potential for industrial effluent treatment. The nanocomposite’s recyclability and minimal efficiency loss over multiple cycles highlight its sustainability for wastewater treatment. Overall, this research fills existing gaps by presenting an advanced, environmentally friendly adsorbent, significantly enhancing the field of wastewater treatment and environmental remediation. The nanocomposite was characterized and used to study Cr(VI) adsorption characteristics. Amount, contact time, pH, and Cr(VI) concentration were found to influence the adsorption characteristics of the nanomaterial. The operating conditions of an adsorbent Al₂O₃@TiFe₂O₄ are optimized utilizing the analysis of the adsorption kinetic data. As shown by the R² responses, which were close to unity, the adsorption behaviour of the nanomaterial is in excellent harmony with the linearized Langmuir isotherm with a maximum capacity of 312.52 mg/g. Additionally, Al₂O₃@TiFe₂O₄ active sites were more observed to be favorable for Cr(VI) ions at all experimental temperatures range, according to calculations of monolayer adsorption capacities using the Langmuir equation. The value of n was 0.40, 0.42, and 0.43, respectively 25, 35, and 45 °C. The adsorbent shows an adsorption capacity of 93 % with the RSD less than 2 %.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103455"},"PeriodicalIF":3.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Groundwater quality assessment using revised classical diagrams and compositional data analysis (CoDa): Case study of Wadi Ranyah, Saudi Arabia","authors":"Drouiche Abdelmalek ,&nbsp;Reghais Azzeddine ,&nbsp;Ahmed Mohamed ,&nbsp;Zahi Faouzi ,&nbsp;Wael F. Galal ,&nbsp;Saad S. Alarifi ,&nbsp;Musaab A.A. Mohammed","doi":"10.1016/j.jksus.2024.103463","DOIUrl":"10.1016/j.jksus.2024.103463","url":null,"abstract":"<div><div>This research aims to assess the status and chemical properties of groundwater in the shallow aquifer of the Wadi Ranyah region, Saudi Arabia, using robust statistical methods (CoDA) that take into account the unique characteristics of chemical analysis data from forty-five (45) groundwater samples collected in the Wadi Ranyah valley. A centered logarithmic transformation (clr) approach and isometric logarithmic transformation (ilr) plots for compositional data were utilized to determine the different water types and to understand the hydrogeochemical processes influencing groundwater chemistry in the region. The results of principal component analysis and K-means clustering reveal the existence of three groundwater groupings: <strong>(i)</strong> The first group occupies the recharge region with a relationship between trace metal elements (F, Pb, Mn, Zn), pH, and TDS, indicating the effect of alteration of igneous and metamorphic rock minerals. <strong>(ii)</strong> The second group characterizes the downstream part of the Al-Hujrah area with a relationship between calcium and nitrates, indicating the influence of agricultural activities. (iii) The third group, located in the Ranyah area, shows a relationship between major ions (Na⁺, SO₄²⁻, Mg²⁺, HCO₃^–, Cl⁻, K⁺), which explains water mineralization influenced by silicate weathering and evaporation phenomena. According to the modified Piper diagram (ilr Piper), two hydrochemical facies are identified. The upstream region is categorized as Ca-HCO₃^– while the downstream region is classified as Na-K-HCO₃^–. Calculated water quality index (WQI) values indicate that all Wadi Ranyah groundwater samples are of very poor quality (WQI &gt; 300). This is due to higher concentrations of polluting elements (Pb, Mn and F), in particular the high lead concentrations which vary between 0.24 and 0.4 mg/L, and are well above the WHO limit (0.01 mg/L) for consumption of drinking water. The application of CoDA for the first time in the study region has provided a more detailed and reliable assessment of the mechanisms governing groundwater quality, permitting suggestions for the management of groundwater resources and defining future research needs.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103463"},"PeriodicalIF":3.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of phases and mechanical properties of magnesium-based high-entropy alloys using machine learning","authors":"Robert Otieno,&nbsp;Edward V. Odhong,&nbsp;Charles Ondieki","doi":"10.1016/j.jksus.2024.103456","DOIUrl":"10.1016/j.jksus.2024.103456","url":null,"abstract":"<div><h3>Objectives</h3><div>To predict phases and mechanical properties of Mg-Al-Cu-Mn-Zn alloys and to validate the results.</div></div><div><h3>Methods</h3><div>In this study, 29 predictor features of the alloys were examined based on dataset drawn from relevant publications. The correlation of selected predictor features with mechanical properties of Mg-Al-Cu-Mn-Zn alloys were evaluated. New features specific to vehicle and aerospace applications were used. Feature selection schemes involving four machine learning (ML) classifiers that included artificial neural networks (ANN), linear discriminant analysis (LDA), random forest regression (RF) and k-nearest neighbours (k-NN) were adopted. Tensile test was carried out based on ASTM E8 standard.</div></div><div><h3>Results</h3><div>Results of correlation of features showed that specific strengths and specific modulus of the alloys were strongly and positively correlated with composition of alloying elements but strongly and negatively correlated with composition of magnesium. The results also revealed that homogenization temperatures and time were weakly correlated with the mechanical properties and phases while electronegativity difference and VEC had significant positive correlation. ANN was the best performing classifier followed by k-NN, LDA, and lastly RF with prediction accuracy on test data of 98.7%, 98.1%, 97.9% and 97.8%, respectively. The validity and applicability of the model was tested with three magnesium-based alloys: Mg-80-Al-10-Cu-5-Mn-5-Zn-0, Mg-80-Al-5-Cu-5-Mn-5-Zn-5 and Mg-91.2-Al-8.3-Cu-0-Mn-0.15-Zn-0.35 and compared with findings in literature. The model had higher prediction accuracies compared to previous ML models used on magnesium alloys. The model was then used to predict phases in the Mg-89.43-Al-8.16-Cu-0.34-Mn-0.25-Zn-1.81 alloy and it accurately predicted presence of Mg₁₇Al₁₂, Mg₂Si, MgZn and MgZn₂. Results of simulation in MatCalc version 6.04 also verified presence of the phases. The phases were further confirmed through SEM/EDS analysis.</div><div>Conclusions.</div><div>Dominant strengthening phases were Mg₁₇Al₁₂, Mg₂Si, MgZn and MgZn_2. Predicted yield strength, ultimate tensile strength and Young’s modulus were within the range of experimental results. Specific strengths and specific modulus were also within the range.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103456"},"PeriodicalIF":3.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142328169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic antibacterial activity of biogenic AgNPs with antibiotics against multidrug resistant bacterial strains","authors":"Khalid Maniah ,&nbsp;Fatimah Olyan Al-Otibi ,&nbsp;Sara Mohamed ,&nbsp;Basant A. Said ,&nbsp;Mohamed Ragab AbdelGawwad ,&nbsp;Mohamed Taha Yassin","doi":"10.1016/j.jksus.2024.103461","DOIUrl":"10.1016/j.jksus.2024.103461","url":null,"abstract":"<div><div>The prevalence of hospital-acquired infections caused by drug resistant bacterial pathogens is a major health risk, leading to a considerable number of deaths and illnesses globally. Therefore, it is essential to develop new combinations of antimicrobial agents to effectively manage drug-resistant bacteria that are responsible for nosocomial infections. A current study aims to synthesize silver nanoparticles (AgNPs) from the seeds of <em>Trigonella foenum-graecum</em> (fenugreek). The AgNPs exhibited a spherical morphology and had an average particle size of 29.75 nm. In addition, XRD examination verified the presence of a face-centered cubic (fcc) lattice structure in the biosynthesized AgNPs, while FTIR study demonstrated the existence of several functional groups such as phenols, alkanes, and amines. The biogenic AgNPs exhibited the most potent antibacterial effect against <em>E. coli</em> strain, with relative inhibitory zone of 18.43 ± 0.35 mm and a minimum inhibitory concentration (MIC) of 50 µg/ml. In addition, the most potent antibacterial effect of AgNPs combined with colistin was observed against <em>Acinetobacter baumannii</em> strain, while the greatest combined efficacy of AgNPs with norfloxacin was found against <em>Pseudomonas aeruginosa</em>, resulting in a relative increase in the fold of inhibition area (IFA) of 0.53 and 0.35, respectively. In conclusion, the potent antibacterial and synergistic effect of AgNPs with antibiotics highlights their potential application of this combination in controlling nosocomial infections in health care settings.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103461"},"PeriodicalIF":3.7,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1018364724003732/pdfft?md5=f7086f6dcb8cc4800503db2628fc26e8&pid=1-s2.0-S1018364724003732-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142316116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological assessment of delphinidin in counteracting polystyrene microplastic induced renal dysfunction in rats","authors":"Nimra Nazir ,&nbsp;Ali Akbar ,&nbsp;Muhammad Zaid Salar ,&nbsp;Mohammad Z. Ahmed ,&nbsp;Ayesha Ishtiaq","doi":"10.1016/j.jksus.2024.103462","DOIUrl":"10.1016/j.jksus.2024.103462","url":null,"abstract":"<div><div>Polystyrene microplastics (PSMP) are toxic environmental contaminants which can damage various body organs including kidneys. Delphinidin (DEL) is a potential anthocyanidin flavonoid with significant pharmacological benefits. This research was conducted to analyze the protective effect of DEL to avert PSMP prompted renal dysfunction. Rats (n = 24) were divided into 4 separate groups: Control, PSMP (0.01 mgkg⁻¹), PSMP (0.01 mgkg⁻¹) + DEL (25 mgkg⁻¹) and only DEL (25 mgkg⁻¹). Our results showed that PSMP exposure reduced the expressions of <em>Nrf-2</em> and antioxidant genes while increasing the expression of <em>Keap1</em>. Besides, PSMP intoxication escalated the level of kidney injury markers (urea, KIM-1, creatinine and NGAL) while inducing substantial reduction in the levels of creatinine clearance. Moreover, PSMP significantly reduced the levels of GSH, GST, SOD, HO-1, CAT, GSR, GPx while escalating MDA and ROS. Conversely, inflammatory biomarkers including IL-1β, TNF-α, NF-kB, IL-6 and COX-2 activity were increased due to PSMP intoxication. Our results showed that PSMP administration increased the expressions of Bax and caspase-3 while decreasing the expression of Bcl-2. However, DEL treatment significantly restored the PSMP-induced renal impairments. Therefore, it is suggested that DEL could be used as a therapeutic compound to alleviate PSMP-induced kidney damage in rats, possibly due to its strong pharmacological properties.</div></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103462"},"PeriodicalIF":3.7,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142419183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative review of processing methods for graphene-based hybrid filler polymer composites and enhanced mechanical, thermal, and electrical properties","authors":"Zulfiqar Ali ,&nbsp;Saba Yaqoob ,&nbsp;Jinhong Yu ,&nbsp;Alberto D’Amore ,&nbsp;M. Fakhar-e-Alam","doi":"10.1016/j.jksus.2024.103457","DOIUrl":"10.1016/j.jksus.2024.103457","url":null,"abstract":"<div><p>Graphene-based hybrid filler polymer composites represent a significant advancement in materials science and engineering due to graphene’s remarkable mechanical, thermal, and electrical properties. This comprehensive review systematically evaluates both traditional (e.g., mechanical and solution mixing) and modern fabrication techniques (e.g., in situ polymerization, chemical modification, electrospinning, and layer-by-layer assembly) employed in the synthesis of these composites, comparing their effectiveness in enhancing material properties such as strength, thermal stability, and conductivity. Emphasizing the synergistic interactions between graphene and other fillers within polymer matrices, the paper discusses mechanisms that lead to superior composite performance. A thorough survey of the literature highlights successful examples where these composites have demonstrated significant advancements in mechanical, thermal, and electrical properties. Three detailed tables summarize findings from published studies, illustrating the enhanced properties and achievements at various filler concentrations across different preparation methods. The review concludes by outlining future research directions aimed at optimizing graphene hybrid filler polymer composites for broader scientific and industrial utilization. By consolidating current knowledge and providing a practical resource, this review aims to guide researchers and practitioners in harnessing the full potential of these advanced materials.</p></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103457"},"PeriodicalIF":3.7,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1018364724003690/pdfft?md5=1a7c982d2edce271364d51a867104889&pid=1-s2.0-S1018364724003690-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142272514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valorisation of Citrus limetta peel for Aspergillus terreus FP6 mediated pectinase fermentation and application in grape juice clarification","authors":"Dibbyangana Mukhopadhyay ,&nbsp;Rajrupa Bhattacharyya ,&nbsp;Sourav Bhattacharya ,&nbsp;Bassam Khalid Alnafisi","doi":"10.1016/j.jksus.2024.103454","DOIUrl":"10.1016/j.jksus.2024.103454","url":null,"abstract":"<div><h3>Objectives</h3><p>The present investigation highlights the process parameters influencing the pectinase fermentation by a newly isolated <em>Aspergillus terreus</em> using valorised agro-wastes and determination of the efficacy of the pectinase in grape juice clarification.</p></div><div><h3>Methods</h3><p>The fungal pectinase was produced under submerged fermentation with the optimisation of carbon and nitrogen sources, initial pH of the medium, inoculum load, incubation time and effect of agitation. The pectinase was later used for the clarification of grape juice and improvement of its total phenolic content.</p></div><div><h3>Results and Conclusions</h3><p>Medium supplemented with sweet lime peel and yeast extract (1 % w/v), at initial pH 6.0, when incubated for 72 h under agitated conditions favoured the highest pectinase production by the fungal culture. Following the pectinase action for 1 and 3 h, the grape juice clarification percentages and total phenolic content were 34.21 %, 69.54 %, 3004, and 3484 mg GAE/L, respectively. The results highlight the valorisation of sweet lime peel for the industrial production of fungal pectinase. The study pronounces the cost-effective pectinase fermentation due to the fungi’s non-fastidious nutritional requirement and ubiquitous nature. The increase in the grape juice clarification and total phenolic content following the <em>A. terreus</em> FP6 pectinase treatment was significantly superior to similar commercial enzyme formulations. The result advocates the candidature of the enzyme in the beverage industry, where it can help mediate a greener approach for fruit juice clarification.</p></div>","PeriodicalId":16205,"journal":{"name":"Journal of King Saud University - Science","volume":"36 10","pages":"Article 103454"},"PeriodicalIF":3.7,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1018364724003665/pdfft?md5=b94e8d6dc9512fe0e6c41f96e2349d70&pid=1-s2.0-S1018364724003665-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142272438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}