S Pepplinkhuizen, N Kors, J A de Veld, L A Dijkshoorn, N R Bijsterveld, A de Weger, L Smeding, A A M Wilde, L R A Olde Nordkamp, R E Knops
{"title":"Antithrombotic therapy and the risk of pocket hematoma after subcutaneous implantable cardioverter-defibrillator implantation.","authors":"S Pepplinkhuizen, N Kors, J A de Veld, L A Dijkshoorn, N R Bijsterveld, A de Weger, L Smeding, A A M Wilde, L R A Olde Nordkamp, R E Knops","doi":"10.1007/s10840-024-01973-x","DOIUrl":"10.1007/s10840-024-01973-x","url":null,"abstract":"<p><strong>Background: </strong>Little data exists regarding the optimal antithrombotic strategy during S-ICD implantation to prevent pocket hematomas. This study explores the association between perioperative antithrombotic management and the occurrence of pocket hematoma following S-ICD implantation.</p><p><strong>Methods: </strong>All patients who underwent de novo S-ICD implantation between February 2009 and January 2023 at Amsterdam UMC were included. Data was collected retrospectively from electronic patient records. Clinically significant pocket hematomas were defined as an accumulation of blood at the pocket site within 30 days after implantation.</p><p><strong>Results: </strong>A total of 347 patients were included of which 224 (64.6%) patients used antithrombotic therapy pre-implantation. The median age at implantation was 50 years (IQR 36-61 years), 33.4% of the patients were female, and the majority of implants were intermuscular (90.2%). A total of 18 patients (5.2%) developed a clinically significant pocket hematoma. There were significantly more pocket hematomas in patients with continued vitamin K antagonists (VKA) compared to patients with interrupted VKA (27.3% (6/22) vs. 4.3% (2/47), respectively, p = 0.01), and continuation of VKA was an independent predictor for pocket hematoma formation in the VKA group (p = 0.04). Moreover, continuation of dual antiplatelet therapy (DAPT) with ticagrelor was associated with significantly more pocket hematomas post-implantation compared to continuation of DAPT with clopidogrel (4/12 vs. 1/28, respectively, p = 0.02).</p><p><strong>Conclusion: </strong>Continuation of VKA during S-ICD implantation was associated with an increased risk of pocket hematoma formation compared to interruption of VKA. This supports the need for specific perioperative antithrombotic therapy guidelines for S-ICD implantations to reduce the risk of pocket hematomas.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Valverde Soria, Pablo J Sanchez-Millan, José Antonio Fernandez-Sanchez, Rosa Macías-Ruiz, Juan Jimenez-Jaimez, Luis Tercedor
{"title":"Successful ablation of Purkinje-related ventricular ectopy leading to ventricular fibrillation in Emery-Dreifuss dilated cardiomyopathy.","authors":"Laura Valverde Soria, Pablo J Sanchez-Millan, José Antonio Fernandez-Sanchez, Rosa Macías-Ruiz, Juan Jimenez-Jaimez, Luis Tercedor","doi":"10.1007/s10840-025-01983-3","DOIUrl":"https://doi.org/10.1007/s10840-025-01983-3","url":null,"abstract":"<p><strong>Introduction: </strong>Mutations in EMD are related to an increased risk of ventricular arrhythmias and sudden cardiac death. There is a lack of data concerning ventricular arrhythmia ablation in Emery-Dreifuss patients.</p><p><strong>Methods and results: </strong>We present a case of successful ablation of a short-coupled ventricular ectopy (VE) triggering recurrent ventricular fibrillation (VF) episodes in a EMD patient with an intraseptal substrate. Our approach combined substrate ablation with ICD-guided pacemapping.</p><p><strong>Conclusion: </strong>VF ablation of Purkinje triggers may be an alternative treatment for patients with dilated cardiomyopathy and recurrent ICD shocks due to VF induced by monomorphic VE.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Right ventricular subclinical dysfunction in high-burden idiopathic outflow tract premature ventricular contraction population.","authors":"Dicky Armein Hanafy, Putri Reno Indrisia, Amiliana Mardiani Soesanto, Dony Yugo Hermanto, Yoga Yuniadi, Aditya Agita Sembiring, Vidya Gilang Rejeki, Muhammad Rizky Felani, Emir Yonas, Sunu Budhi Raharjo, Amin Al-Ahmad","doi":"10.1007/s10840-024-01976-8","DOIUrl":"https://doi.org/10.1007/s10840-024-01976-8","url":null,"abstract":"<p><strong>Background: </strong>The relationship between premature ventricular contractions (PVC) and right ventricular (RV) function is not widely known. Left ventricular (LV) dysfunction due to PVC is known as PVC-induced cardiomyopathy (PIC) and suppressing the PVC substrate would improve LV function. The effect of PVC ablation on changes in RV function in patients with subtle RV subclinical dysfunction remains unknown.</p><p><strong>Objective: </strong>Understanding the alterations in RV function parameters after PVC ablation.</p><p><strong>Method: </strong>Basic and speckle-tracking echocardiography has been performed on 42 individuals with symptomatic idiopathic outflow tract PVC before and 1 month after a successful ablation.</p><p><strong>Result: </strong>At the baseline of the study, there were 26 patients with RV subclinical dysfunction and 16 patients without RV dysfunction. Patients with RV subclinical dysfunction exhibited significantly higher PVC burden and QRS complex duration than those with normal RV function (p < 0.05). A PVC burden ≥ 21% (OR 9.11, 1.54-53.87, p = 0.015) and a QRS complex duration ≥ 138 ms (OR 5.74, 1.07-30.90, p = 0.042) were independently associated with RV subclinical dysfunction. In both groups, measurements of RV subclinical function before and after ablation, specifically by free wall longitudinal strain (FWLS) and global longitudinal strain (GLS), demonstrated significant changes. These improvements were more pronounced in the group with RV dysfunction (FWLS 9.7 ± 4.0, p < 0.001; GLS 7.5 ± 4.2, p < 0.001). Lower initial FWLS and GLS before ablation emerged as significant parameters in the multivariate analysis for the improvement of RV function post-ablation.</p><p><strong>Conclusion: </strong>Patients with RV subclinical dysfunction had higher PVC burden and wider QRS duration. Patients with idiopathic outflow tract PVC with RV subclinical dysfunction may experience improvements in RV function after successful PVC ablation.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo M Kulchetscki, Paulo Henrique Peitl Gregório, Gabrielle D 'Arezzo Pessente, Cristiano F Pisani, Muhieddine O Chokr, Carina A Hardy, Luciana Sacilotto, Francisco Carlos da Costa Darrieux, Denise Hachul, Mauricio I Scanavacca, Paulo M Pêgo-Fernandes
{"title":"Unicentric Brazilian registry of cardiac sympathetic denervation for control of ventricular arrhythmias.","authors":"Rodrigo M Kulchetscki, Paulo Henrique Peitl Gregório, Gabrielle D 'Arezzo Pessente, Cristiano F Pisani, Muhieddine O Chokr, Carina A Hardy, Luciana Sacilotto, Francisco Carlos da Costa Darrieux, Denise Hachul, Mauricio I Scanavacca, Paulo M Pêgo-Fernandes","doi":"10.1007/s10840-024-01975-9","DOIUrl":"https://doi.org/10.1007/s10840-024-01975-9","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alireza Ghajar, Maeve M Sargeant, John N Catanzaro, Binu Philips, Fabrizio R Assis, Rajasekhar Nekkanti, Samuel F Sears, Ghanshyam Shantha
{"title":"US National trends in mortality related to ventricular tachycardia/ ventricular fibrillation.","authors":"Alireza Ghajar, Maeve M Sargeant, John N Catanzaro, Binu Philips, Fabrizio R Assis, Rajasekhar Nekkanti, Samuel F Sears, Ghanshyam Shantha","doi":"10.1007/s10840-025-01979-z","DOIUrl":"https://doi.org/10.1007/s10840-025-01979-z","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Fusaroli, Mark G Hoogendijk, Rohit E Bhagwandien, Sip A Wijchers, Nick van Boven, Bakthawar K Mahmoodi, Sing-Chien Yap
{"title":"Optimized workflow with hybrid (very) high-power short-duration radiofrequency ablation renders point-by-point pulmonary vein isolation as fast and effective as cryoballoon ablation.","authors":"Marco Fusaroli, Mark G Hoogendijk, Rohit E Bhagwandien, Sip A Wijchers, Nick van Boven, Bakthawar K Mahmoodi, Sing-Chien Yap","doi":"10.1007/s10840-025-01982-4","DOIUrl":"https://doi.org/10.1007/s10840-025-01982-4","url":null,"abstract":"<p><strong>Introduction: </strong>A hybrid approach with very high-power short-duration (vHPSD) posteriorly and ablation-index guided HPSD (50 W) anteriorly seems to be an optimal balance between efficiency and effectiveness for point-by-point pulmonary vein isolation (PVI). The aim of the current study is to compare vHPSD/HPSD ablation to cryoballoon ablation (CBA) in patients with symptomatic atrial fibrillation (AF).</p><p><strong>Methods and results: </strong>In this retrospective single-center study, we identified 110 consecutive patients who underwent their first PVI with either vHPSD/HPSD (n = 54) or CBA (n = 56). We compared procedural efficacy, efficiency, safety, and long-term outcomes. Baseline characteristics of both groups were comparable; however, patients in the vHPSD/HPSD group had larger left atrial volume index (35, IQR 27-45 vs. 28, IQR 21-36 ml/m<sup>2</sup>, P = 0.005). Complete PVI was achieved in all patients except two CBA cases (100% vs. 96.4%, P = 0.50). First-pass isolation rate was 79.6% in the hybrid group. Procedure times were similar between groups (53, IQR 47-63 vs. 55, IQR 49-65 min, P = 0.35), but fluoroscopy time was shorter in the vHPSD/HPSD group (3.9 [2.7, 5.6] vs. 11.9 [9.3, 14.9] min, P < 0.001). There were 3 temporary phrenic nerve palsies (5.4%) in the CBA group which resolved within 1 year. The 1-year freedom from any atrial tachyarrhythmias after a single procedure was similar between groups (68.5% vs. 73.2%, P = 0.56). During repeat procedure, the durability of PVI was comparable.</p><p><strong>Conclusions: </strong>The use of vHPSD/HPSD ablation renders point-by-point PVI as fast and effective as CBA. Furthermore, it has lower radiation exposure compared to CBA.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haider Al Taii, Ritika Saxena, Ramez Morcos, Ali Saad Al-Shammari, Kassem Farhat, Ahmed Sermed Al Sakini, Ameer Al-Wssawi, Diann Gaalema, Arun Naraynan, Dean Sabayon, Aiham Albani, Hani Jneid
{"title":"Outcomes of catheter ablation in cardiac sarcoidosis patients with ventricular tachycardia: a propensity score-matched retrospective analysis.","authors":"Haider Al Taii, Ritika Saxena, Ramez Morcos, Ali Saad Al-Shammari, Kassem Farhat, Ahmed Sermed Al Sakini, Ameer Al-Wssawi, Diann Gaalema, Arun Naraynan, Dean Sabayon, Aiham Albani, Hani Jneid","doi":"10.1007/s10840-025-01986-0","DOIUrl":"https://doi.org/10.1007/s10840-025-01986-0","url":null,"abstract":"<p><strong>Background: </strong>Ventricular tachycardia (VT) in patients with cardiac sarcoidosis (CS) can lead to sudden cardiac death. The role of ventricular tachycardia ablation (VTA) in CS has been investigated in a few small, single-center, and larger observational studies, but the evidence still needs to be provided. This study aimed to investigate the clinical outcomes of VTA in patients with CS admitted with a diagnosis of VT.</p><p><strong>Methods: </strong>A retrospective analysis was conducted using the TriNetX database: US collaborative network from 2010 to 2024. Patients undergoing ablation for VT with and without CS were identified. Two groups were created for propensity score analysis matching a history of hypertension, diabetes, obesity, peripheral vascular diseases, heart failure, ischemic heart diseases, atrial fibrillation, and chronic kidney disease. The primary outcome was the incidence of death, cardiogenic shock, heart failure, acute myocardial infarction, hemorrhagic stroke, ischemic stroke, and ventricular tachycardia within 1 year from the date of the index procedure.</p><p><strong>Results: </strong>Out of 15,958 patients who underwent catheter ablation for VT, 778 patients had CS. After propensity matching, the mean age of patients with VT and CS who underwent ablation was 58.6 (SD = 11.3), compared to 59.5 (SD = 13) in patients with VT without CS (p-value = 0.07). The propensity-matched analysis showed no significant differences in procedure-related complications between those with cardiac sarcoidosis (CS) and those without. Both cohorts had 10 events each for cardiac tamponade (p = 0.195), groin hematoma requiring transfusion (p = 0.102), pneumothorax (p = 0.317), and sepsis (p = 0.654). Cardiogenic shock occurred in 13 patients in the non-CS group versus 12 in the CS group (p = 0.840). At the 1-year follow-up, there was no significant difference in the mortality rate between the two groups (HR = 1.228, 95% CI 0.834-1.809, p = 0.298). Cardiogenic shock was also similar, with 13 events in the non-CS group and 12 in the CS group (HR = 0.879, 95% CI 0.636-1.213, p = 0.430). However, CS was associated with a higher risk of acute exacerbation of heart failure (314 in non-CS vs. 378 in CS, HR = 0.823, 95% CI 0.709-0.956, p = 0.010) and a lower risk of acute myocardial infarction (96 in non-CS vs. 74 in CS, HR = 1.389, 95% CI 1.026-1.881, p = 0.033). There was no significant difference in ICD shock (147 in non-CS vs. 185 in CS, HR = 0.817, 95% CI 0.658-1.014, p = 0.066), ischemic stroke (10 cases each, HR = 0.941, 95% CI 0.382-2.316, p = 0.895), or hemorrhagic stroke (10 cases each, HR = 1.455, 95% CI 0.326-6.501, p = 0.620). However, CS was associated with a higher risk of pericarditis (91 in non-CS vs. 151 in CS, HR = 0.593, 95% CI 0.457-0.769, p < 0.05). At the 5-year follow-up, CS was associated with a lower risk of mortality (123 deaths in non-CS vs. 104 in CS, HR = 1.341, 95% CI 1.033-1.741, p = 0.027) and a lower ris","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yang Pang, Ye Xu, Kuan Cheng, Chaofeng Chen, Qingxing Chen, Yunlong Ling, Guijian Liu, Junbo Ge, Wenqing Zhu
{"title":"A new insight into the anatomical ablation approach at R-L ILT for VAs with a left ventricular summit origination: electrophysiological characteristics and catheter ablation.","authors":"Yang Pang, Ye Xu, Kuan Cheng, Chaofeng Chen, Qingxing Chen, Yunlong Ling, Guijian Liu, Junbo Ge, Wenqing Zhu","doi":"10.1007/s10840-024-01974-w","DOIUrl":"https://doi.org/10.1007/s10840-024-01974-w","url":null,"abstract":"<p><strong>Background: </strong>Ventricular arrhythmia (VA) originating from the left ventricular summit (LVS) poses particular challenges, with higher rates of ablation failure.</p><p><strong>Objective: </strong>To further evaluate the anatomical ablation approach from the subaortic region for LVS VAs and their electrophysiological characteristics.</p><p><strong>Method: </strong>The study enrolled 27 consecutive patients with sympatomatic VAs originating from LVS and who received an anatomical ablation approach from R-L ILT in our center.</p><p><strong>Results: </strong>Three different mapping results were obtained as the earliest activation sites (EAS) were observed in the RVOT region (group 1), R-L ILT (group 2), and epicardial region (group 3), respectively. A higher percentage of rS/QS patterns in lead I was observed in Groups 1 and 3. A narrower QRS duration was observed in Group (1) A presystolic potential was recorded at R-L ILT for most VAs in group (2) All VAs were successfully ablated at R-L ILT in groups 1 and 2, though poor pace mapping results were observed at R-L ILT. 4/7 VAs in group 3 ultimately failed after an ablation in both the endocardial and epicardial regions.</p><p><strong>Conclusion: </strong>An anatomical ablation approach at R-L ILT was effective for most VAs with an LVS origin. Different ECG and electrophysiological characteristics could be observed in VAs with different EAS. Poor pace mapping results in all regions with an EAS in the epicardial region had predictive value for the failure of the ablation procedure.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucio Addeo, Chiara Valeriano, Stefano Valcher, Vincenza Abbate, Raffaella Mistrulli, Dimitri Buytaert, Peter Geelen, Peter Peytchev, Koen De Schouwer, Tom De Potter
{"title":"Ultrasound-guided puncture of femoral veins versus standard palpation approach in patients undergoing pulmonary vein isolation.","authors":"Lucio Addeo, Chiara Valeriano, Stefano Valcher, Vincenza Abbate, Raffaella Mistrulli, Dimitri Buytaert, Peter Geelen, Peter Peytchev, Koen De Schouwer, Tom De Potter","doi":"10.1007/s10840-024-01977-7","DOIUrl":"https://doi.org/10.1007/s10840-024-01977-7","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}