Christian-H Heeger, Leonie Zetzsch, Charlotte Eitel, Jan-Per Wenzel, Sorin Ștefan Popescu, Henning Rolfes, Sascha Hatahet, Behnam Subin, Karl-Heinz Kuck, Roland R Tilz
{"title":"Pulsed field ablation-based pulmonary vein isolation utilizing a simplified approach or a standard approach-insights from the fast and furious PFA study.","authors":"Christian-H Heeger, Leonie Zetzsch, Charlotte Eitel, Jan-Per Wenzel, Sorin Ștefan Popescu, Henning Rolfes, Sascha Hatahet, Behnam Subin, Karl-Heinz Kuck, Roland R Tilz","doi":"10.1007/s10840-025-02046-3","DOIUrl":"10.1007/s10840-025-02046-3","url":null,"abstract":"<p><strong>Background: </strong>Pulsed field ablation (PFA) is a novel non-thermal energy source. Recently, we developed a tailored and streamlined pulmonary vein isolation (PVI) approach utilizing a pentaspline PFA catheter via a single access, single catheter approach. This study was aimed at comparing safety, efficacy, and follow-up of this approach with a conventional approach.</p><p><strong>Methods and results: </strong>Fifty consecutive patients with atrial fibrillation (AF) underwent first-time PVI via PFA under deep sedation. The first 25 patients were treated with a conventional approach utilizing two femoral vein access sheath inclusive utilization of 3D mapping and a coronary sinus catheter (conventional approach, control group). The second 25 patients were treated via a simplified single venous, single transseptal puncture, single catheter approach utilizing a vascular closure system (Fast and Furious PFA approach, FAST group). A total of 194 PVs were identified and isolated with PFA only (100%). The median procedural time was 26 (25, 30) min (FAST) and 65 (59, 72) min (control), respectively (P < 0.0001). The median fluoroscopy time was 5 (4, 7) min (FAST) and 12 (10, 14) min (control), respectively (P < 0.001). Freedom from AF recurrence at 12 months was 77% for the FAST group (vs.</p><p><strong>Control: </strong>81%, P = 0.856, and overall: 79%).</p><p><strong>Conclusion: </strong>The combination of a single venous puncture, single transseptal puncture approach utilizing PFA and vascular closure device resulted in a 100% rate of acute PVI and fast procedure with comparable safety, acute efficacy and 12-month outcome to the conventional approach.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"213-220"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy, safety, and somatosensory comparison of pulsed-field ablation and thermal ablation: outcomes from a 2-year follow-up.","authors":"Jiale Wang, Xinqi Wang, Wei Liu, Haoyuan Hu, Jiahui Zhao, Changhao Hu, Weiwen Zhao, Youran Qin, Kaiqing Yang, Songyun Wang, Hong Jiang","doi":"10.1007/s10840-024-01966-w","DOIUrl":"10.1007/s10840-024-01966-w","url":null,"abstract":"<p><strong>Background: </strong>Pulsed-field ablation (PFA), as a nonthermal ablative approach for atrial fibrillation, has attracted much attention in recent years. And there are few comparative studies on PFA versus conventional thermal ablation, including radiofrequency ablation (RFA) and cryoballoon ablation (CBA). The efficacy, safety, and somatic sensation of PFA and thermal ablation need to be further compared.</p><p><strong>Methods: </strong>A total of 109 patients with paroxysmal atrial fibrillation were divided into three groups (27 in the PFA group, 41 in the CBA group, and 41 in the RFA group), and the operation characteristics, efficacy, safety, and somatic sensation were recorded and analyzed. All patients were followed for 2 years.</p><p><strong>Results: </strong>All pulmonary veins were successfully isolated except for 1 pulmonary vein that was not successfully isolated during the CBA process (PFA vs. CBA vs. RFA = 100% vs. 99% vs. 100%). The total operation time for PFA is considerably shorter than that for thermal ablation (PFA vs. CBA vs. RFA = 65.28 ± 22.78 min vs. 75.38 ± 18.53 min vs. 96.26 ± 23.23 min, P < 0.001), and the same applies to all the sub-phases. PFA was similarly more dominant in terms of somatosensory perception, mainly in headache (PFA vs. CBA = 1.17 ± 0.48 vs. 2.31 ± 1.06, P < 0.001) and chest pain (PFA vs. RFA = 1.45 ± 0.88 vs. 2.52 ± 1.06, P < 0.001). All these three groups demonstrated good maintenance rates (PFA vs. CBA vs. RFA = 85.00% vs. 80.49% vs. 78.05%, 2 years after operation).</p><p><strong>Conclusion: </strong>PFA demonstrates its excellent somatic sensation and favorable safety. And it also showed a great immediate success and maintenance rate, which is not inferior to thermal ablation.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"201-211"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Auroa Badin, Sreedhar R Billakanty, David M Nemer, Ankur N Shah, Andrea K Robinson, Allyson Farrah, Nagesh Chopra, Elizabeth Richards, Anish K Amin
{"title":"Learning curve of pulsed field ablation for atrial fibrillation: insights from a United States center.","authors":"Auroa Badin, Sreedhar R Billakanty, David M Nemer, Ankur N Shah, Andrea K Robinson, Allyson Farrah, Nagesh Chopra, Elizabeth Richards, Anish K Amin","doi":"10.1007/s10840-025-02043-6","DOIUrl":"10.1007/s10840-025-02043-6","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"151-152"},"PeriodicalIF":2.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmoud Khalil, Ahmed Hashim, Ahmed Maraey, Ayman Saeyeldin, Ahmed M Elzanaty, Patrick Biskupski, Kenneth Ong, Chirag R Barbhaiya, Mohamed Shokr
{"title":"Correction to: Outcomes of conventional pacemaker implantation in patients with dementia: insights from the National Readmission Database.","authors":"Mahmoud Khalil, Ahmed Hashim, Ahmed Maraey, Ayman Saeyeldin, Ahmed M Elzanaty, Patrick Biskupski, Kenneth Ong, Chirag R Barbhaiya, Mohamed Shokr","doi":"10.1007/s10840-023-01540-w","DOIUrl":"10.1007/s10840-023-01540-w","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1947"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9288766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmoud Khalil, Ahmed Maraey, Amro Aglan, Emmanuel Akintoye, Mahmoud Salem, Ahmed M Elzanaty, Ahmed Younes, Ayman Saeyeldin, Chirag R Barbhaiya, Mohamed Shokr
{"title":"Correction: Impact of chronic kidney disease on in-hospital mortality and clinical outcomes of catheter ablation of ventricular tachycardia: Insights from the national readmission database.","authors":"Mahmoud Khalil, Ahmed Maraey, Amro Aglan, Emmanuel Akintoye, Mahmoud Salem, Ahmed M Elzanaty, Ahmed Younes, Ayman Saeyeldin, Chirag R Barbhaiya, Mohamed Shokr","doi":"10.1007/s10840-023-01539-3","DOIUrl":"10.1007/s10840-023-01539-3","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1945"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9235657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between left atrial slow conduction velocity and recurrence of atrial fibrillation: a prospective study based on high-density mapping.","authors":"Dan Qi, Xiaonan Guan, Xiaoqing Liu, Lifeng Liu, Zheng Liu, Jianjun Zhang","doi":"10.1007/s10840-025-02052-5","DOIUrl":"10.1007/s10840-025-02052-5","url":null,"abstract":"<p><strong>Background: </strong>The level of atrial remodeling is closely related to the recurrence of atrial fibrillation (AF). Although structural remodeling has been extensively evaluated, methods for assessing atrial electrical remodeling have not been established. The purpose of our study is to investigate the relationship between atrial conduction velocity and the recurrence of atrial fibrillation (AF) following radiofrequency ablation with pulmonary vein isolation.</p><p><strong>Methods and results: </strong>We prospectively enrolled 155 patients with paroxysmal atrial fibrillation who underwent their first AF ablation at our center. High-density bipolar voltage mapping was conducted during sinus rhythm in all patients. A coherent mapping was constructed to accurately evaluate the total conduction time, distance, and left atrial conduction velocity (LACV) on the anterior, posterior, and septal routes between the earliest and latest activation sites during sinus rhythm. Out of the patients, 24 experienced a recurrence of AF. The LACV was significantly lower in the patients with AF recurrence compared to those without (anterior, 0.81 ± 0.03 vs. 1.07 ± 0.02 m/s, p < 0.01; posterior, 1.06 ± 0.05 vs. 1.32 ± 0.03 m/s, p < 0.01; septal, 0.91 ± 0.05 vs. 1.13 ± 0.02 m/s, p < 0.01). A multivariate logistic analysis, which included age, left atrial diameter (LAD), LA low-voltage area, P-wave duration, and LA conduction velocity, demonstrated that a slow anterior left atrial conduction velocity (LACV) was an independent predictor of AF recurrence with an adjusted odds ratio of 1.64 (95% confidence interval [CI]: 1.24-3.78, p < 0.01). ROC curve analysis confirmed that the anterior LACV was the most accurate predictor of AF recurrence after pulmonary vein isolation (PVI) with a cut-off value of 0.83 m/s, a sensitivity of 93.9%, and a specificity of 70.8%. Anterior LACV was lower in patients with low-voltage areas than in those without low-voltage areas (0.81 ± 0.03 vs. 1.09 ± 0.02 cm/s, p < 0.01).</p><p><strong>Conclusion: </strong>An anterior LACV < 0.83 m/s was identified as a strong independent predictor of AF recurrence after PVI in patients with paroxysmal AF.</p>","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1813-1822"},"PeriodicalIF":2.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronically jailed right ventricular implantable cardioverter defibrillator lead visualized with imaging integration prior to ventricular tachycardia ablation.","authors":"Nithi Tokavanich, Jackson Liang","doi":"10.1007/s10840-025-02054-3","DOIUrl":"10.1007/s10840-025-02054-3","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1809-1810"},"PeriodicalIF":2.6,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12644152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Bilal Munir, Alan Sugrue, Nicholas Y Tan, Freddy Del-Carpio Munoz, Siva K Mulpuru, Yong-Mei Cha, Christopher V DeSimone, Abhishek Deshmukh
{"title":"Regional differences in the outcomes of leadless pacemaker implantation in the USA.","authors":"Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Bilal Munir, Alan Sugrue, Nicholas Y Tan, Freddy Del-Carpio Munoz, Siva K Mulpuru, Yong-Mei Cha, Christopher V DeSimone, Abhishek Deshmukh","doi":"10.1007/s10840-025-02023-w","DOIUrl":"10.1007/s10840-025-02023-w","url":null,"abstract":"","PeriodicalId":16202,"journal":{"name":"Journal of Interventional Cardiac Electrophysiology","volume":" ","pages":"1699-1702"},"PeriodicalIF":2.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143501966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}