Acute mitral block: pulse field ablation plus radiofrequency ablation when compared to radiofrequency ablation plus ethanol injection of vein of Marshall.

IF 2.1 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Interventional Cardiac Electrophysiology Pub Date : 2024-12-05 DOI:10.1007/s10840-024-01963-z

Alexander Cubberley, Amir A Ahmadian-Tehrani, Medhansh Kashyap, Taylor Pickering, Mustafa Dohadwala

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引用次数: 0

Abstract

This retrospective study evaluated two groups: patients receiving RFA for PVI, posterior wall isolation, mitral isthmus, and coronary sinus (CS) ablation with adjunctive VOM ethanol injection (VOM/RFA ALL (N = 53)), and patients receiving PVI with PFA using pentaspline catheter followed by mitral isthmus and CS ablation with RFA (PFA PV + PW/RFA MITRAL (N = 12)). We hypothesized that PFA for pulmonary vein isolation (PVI) facilitates mitral block without adjunctive vein of Marshall (VOM) ethanol injection. Mitral block was achieved in 92.5% of VOM/RFA ALL patients and 83.3% of the PFA PV + PW/RFA MITRAL group (p = 0.31). Endocardial ablation time of the mitral isthmus and RF applications required to achieve a complete block were significantly shorter in the VOM/RFA ALL group (208 s vs 356 s, p < 0.01 and 14.5 vs 24.0, p < 0.01, respectively). Adjunctive VOM ethanol injection appears to still have a role for facilitation of mitral isthmus block in the new era of PFA.

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急性二尖瓣阻滞：脉冲场消融加射频消融与射频消融加乙醇注射马歇尔静脉的比较。

本回顾性研究评估了两组患者：接受RFA治疗PVI，后壁隔离，二尖瓣峡部和冠状窦（CS）消融辅助VOM乙醇注射（VOM/RFA ALL (N = 53)）的患者，以及接受PVI并使用PFA的患者，使用pentaspline导管，然后使用RFA进行二尖瓣峡部和CS消融（PFA PV + PW/RFA mitral (N = 12)）。我们假设PFA用于肺静脉隔离（PVI）促进二尖瓣阻塞而不辅助静脉马歇尔（VOM）乙醇注射。VOM/RFA ALL患者的二尖瓣阻滞率为92.5%，PFA PV + PW/RFA二尖瓣阻滞率为83.3% （p = 0.31）。在VOM/RFA ALL组中，实现完全阻断所需的二尖瓣峡部心内膜消融时间和射频应用时间显著缩短（208秒vs 356秒，p . 571）

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来源期刊

Journal of Interventional Cardiac Electrophysiology 医学-心血管系统

CiteScore

4.30

自引率

11.10%

发文量

320

审稿时长

4-8 weeks

期刊介绍： The Journal of Interventional Cardiac Electrophysiology is an international publication devoted to fostering research in and development of interventional techniques and therapies for the management of cardiac arrhythmias. It is designed primarily to present original research studies and scholarly scientific reviews of basic and applied science and clinical research in this field. The Journal will adopt a multidisciplinary approach to link physical, experimental, and clinical sciences as applied to the development of and practice in interventional electrophysiology. The Journal will examine techniques ranging from molecular, chemical and pharmacologic therapies to device and ablation technology. Accordingly, original research in clinical, epidemiologic and basic science arenas will be considered for publication. Applied engineering or physical science studies pertaining to interventional electrophysiology will be encouraged. The Journal is committed to providing comprehensive and detailed treatment of major interventional therapies and innovative techniques in a structured and clinically relevant manner. It is directed at clinical practitioners and investigators in the rapidly growing field of interventional electrophysiology. The editorial staff and board reflect this bias and include noted international experts in this area with a wealth of expertise in basic and clinical investigation. Peer review of all submissions, conflict of interest guidelines and periodic editorial board review of all Journal policies have been established.