Journal of Investigative Surgery最新文献

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Association of miR-203 Expression with Prognostic Value in Patients with Esophageal Cancer: A Systematic Review and Meta-Analysis. 食管癌患者miR-203表达与预后价值的关联:一项系统综述和荟萃分析
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2023-12-01 Epub Date: 2023-12-04 DOI: 10.1080/08941939.2023.2285780
Qirun Cheng, Lipeng Chen, Liping Ni
{"title":"Association of miR-203 Expression with Prognostic Value in Patients with Esophageal Cancer: A Systematic Review and Meta-Analysis.","authors":"Qirun Cheng, Lipeng Chen, Liping Ni","doi":"10.1080/08941939.2023.2285780","DOIUrl":"10.1080/08941939.2023.2285780","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the association between miR-203 expression and the prognostic value in patients with esophageal cancer by the method of systematic review and meta-analysis.</p><p><strong>Methods: </strong>We searched PubMed, Web of Science, Embase, and Cochrane Library to collect studies on the relationship between miR-203 expression and the prognostic value of esophageal cancer up to July 2023. Stata 15.0 statistical software was used for data analysis. Hazard ratio (HR) and 95% confidence interval (CI) were used as effect sizes.</p><p><strong>Results: </strong>A total of 6 studies were included in this review, including 476 patients with esophageal cancer. The results showed that miR-203 low expression was associated with worse overall survival (OS) in patients with esophageal cancer compared with miR-203 high expression (HR = 2.80, 95%CI: 1.99 ∼ 3.93, <i>p</i> < 0.001). The results of Egger's (<i>p</i> = 0.154) and Begg's Tests (<i>p</i> = 0.221) indicated no obvious publication bias. Sensitivity analysis verified the robustness of the results obtained in this study.</p><p><strong>Conclusion: </strong>The expression of miR-203 is significantly correlated with the prognostic value in patients with esophageal cancer. Esophageal cancer patients with high expression of miR-203 had better prognosis than those with low expression of miR-203. Due to the limited studies included in this meta-analysis, more trials are needed to confirm the conclusions of this study in the future.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"36 1","pages":"2285780"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138477835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Distinct Pattern of Granulomatous Lobular Mastitis with Erythema Nodosum: More Severe Conditions and Extensive Lesions. 小叶性肉芽肿性乳腺炎伴结节性红斑的独特模式:更严重的情况和广泛的病变。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2023-09-08 Epub Date: 2023-10-24 DOI: 10.1080/08941939.2023.2257770
Bilian Zheng, Man Lu, Chuang Chen, Shengrong Sun
{"title":"The Distinct Pattern of Granulomatous Lobular Mastitis with Erythema Nodosum: More Severe Conditions and Extensive Lesions.","authors":"Bilian Zheng,&nbsp;Man Lu,&nbsp;Chuang Chen,&nbsp;Shengrong Sun","doi":"10.1080/08941939.2023.2257770","DOIUrl":"10.1080/08941939.2023.2257770","url":null,"abstract":"<p><strong>Purpose: </strong>Granulomatous lobular mastitis (GLM) is a benign inflammatory disease of the mammary gland with unknown etiology. Erythema nodosum (EN) is a rare, extramammary symptom of GLM. The purpose of this article was to investigate the clinical features of EN associated with GLM.</p><p><strong>Methods: </strong>We recruited 102 GLM patients diagnosed between December 2018 and December 2021 at Renmin Hospital of Wuhan University. The clinical characteristics and laboratory indices of the EN group (<i>n</i> = 12) and the non-EN group (<i>n</i> = 90) were compared.</p><p><strong>Results: </strong>The proportion of GLM patients with lesions involving ≥2 quadrants and high peripheral white blood cell count, absolute neutrophil count and neutrophil-to-lymphocyte ratio (NLR) was larger in the EN group than in the non-EN group (<i>p</i> = 0.002, 0.025, 0.014, 0.002, respectively). The duration of EN was longer in GLM patients with EN than in GLM patients without EN (<i>p</i> = 0.005). GLM patients with EN had more abscesses and sinus tracts than those without EN (<i>p</i> = 0.003, 0.038). Lesions involving ≥2 quadrants and the NLR were positively associated with the occurrence of EN (<i>R</i> = 0.304, 0.0302, <i>p</i> = 0.002, 0.002). Receiver operating characteristic curve analysis revealed that the area under the curve of the NLR was 0.770. When NLR > 5.73, the sensitivity and specificity of predicting EN were 66.67% and 87.78%, respectively.</p><p><strong>Conclusion: </strong>Our findings suggest that GLM concomitant with EN suggests the presence of a more severe condition and extensive lesions.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"36 1","pages":"2257770"},"PeriodicalIF":1.9,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50158115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Splenic Abscesses in Endocarditis: A Rare Disease with High Mortality. The Experience of a Heart Institute in Brazil. 心内膜炎的脾脓肿:一种死亡率高的罕见疾病。巴西心脏研究所的经验。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-11-01 Epub Date: 2022-10-06 DOI: 10.1080/08941939.2022.2130481
Roberto Rasslan, Vinicios Alves, Sergio Henrique Bastos Damous, Antonio de Santis, Flavio Tarasoutchi, Calos Augusto Metidieri Menegozzo, Masahiko Akamine, Samir Rasslan, Edivaldo Massazo Utiyama
{"title":"Splenic Abscesses in Endocarditis: A Rare Disease with High Mortality. The Experience of a Heart Institute in Brazil.","authors":"Roberto Rasslan,&nbsp;Vinicios Alves,&nbsp;Sergio Henrique Bastos Damous,&nbsp;Antonio de Santis,&nbsp;Flavio Tarasoutchi,&nbsp;Calos Augusto Metidieri Menegozzo,&nbsp;Masahiko Akamine,&nbsp;Samir Rasslan,&nbsp;Edivaldo Massazo Utiyama","doi":"10.1080/08941939.2022.2130481","DOIUrl":"https://doi.org/10.1080/08941939.2022.2130481","url":null,"abstract":"<p><strong>Introduction: </strong>Splenic abscess secondary to endocarditis is a rare complication with high mortality. The treatment modality, splenectomy versus percutaneous drainage, and the best time, before or after valve replacement, are controversial. In the literature, there are only a few small case series about the subject. The objective of this study is to analyze the experience of a referral center in treating such condition.</p><p><strong>Methods: </strong>Patients with splenic abscesses due to endocarditis from 2006 to 2020 were retrospectively analyzed.</p><p><strong>Results: </strong>Thirteen patients (mean age 46 years old, 69% male) were identified. Eight patients (62%) had at least 2 comorbidities and 5 (38%) had a history of cardiac surgery. The diagnosis was incidental in 6 (46%). The mean time of abscess diagnosis after endocarditis definition was 14 days. Six patients (46%) had at least two organ dysfunctions. The median APACHE II score was 12 overall, and 24.5 in patients who died. Six patients (46%) had a valve replacement, and in two the abscess was diagnosed postoperatively. Of the other four patients, splenectomy was performed before the cardiac operation in three and at the same time in one. Splenectomy was performed immediately in 9 (69%) patients while three patients had percutaneous drainage (23%), one of which underwent splenectomy due to drainage failure. Exclusive antibiotic treatment was performed on only one patient. The median length of hospitalization was 24 days and mortality was 46%.</p><p><strong>Conclusion: </strong>Splenic abscess due to endocarditis is a life-threatening condition with controversial treatment that results in a prolonged length of stay and high mortality.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 11-12","pages":"1836-1840"},"PeriodicalIF":1.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33489850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of the Gastroprotective Effect of Betaine-Homocysteine Homeostasis on Oxidative Stress, Inflammation and Apoptosis in Ethanol-Induced Ulcer Model. 甜菜碱-同型半胱氨酸稳态对乙醇性溃疡模型氧化应激、炎症和细胞凋亡保护作用的研究。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-11-01 Epub Date: 2022-09-25 DOI: 10.1080/08941939.2022.2126566
Ayşe Çakır Gündoğdu, Fatih Kar, Cansu Özbayer
{"title":"Investigation of the Gastroprotective Effect of Betaine-Homocysteine Homeostasis on Oxidative Stress, Inflammation and Apoptosis in Ethanol-Induced Ulcer Model.","authors":"Ayşe Çakır Gündoğdu,&nbsp;Fatih Kar,&nbsp;Cansu Özbayer","doi":"10.1080/08941939.2022.2126566","DOIUrl":"https://doi.org/10.1080/08941939.2022.2126566","url":null,"abstract":"<p><p><b>Background:</b> There is a growing interest in the use of natural compounds for the treatment of gastric ulcers. The multifunctional roles of betaine in various diseases make this natural substance a favorable pre-drug for ulcer treatment. This study aims to determine the competence of betaine in gastroprotection against ethanol-induced damage and to explore underlying mechanisms considering its effects on liver and kidney activity and blood parameters.<b>Methods:</b> <i>Wistar albino</i> rats were orally treated with vehicle (distilled water) or betaine (250 mg/kg) for twenty-one days and then ulcer formation was induced by ingestion of 75% ethanol. Gastric mucosal damage was evaluated by gross examination and histopathological analysis. Homocysteine levels, lipid peroxidation, total antioxidant status (TAS), total oxidant status (TAS), antioxidant enzymes and pro-inflammatory and anti-inflammatory cytokines levels were assessed by enzyme-linked immunosorbent assay (ELISA) or immunohistochemistry. Furthermore, routine biochemical tests were performed and hematological parameters were analyzed.<b>Results:</b> Betaine ameliorated any gastric mucosal damage and reduced homocysteine levels significantly. The TOS and malondialdehyde (MDA) levels were decreased while the TAS, glutathione (GSH) levels and catalase (CAT) activity were increased upon the betaine treatment. Betaine reduced apoptosis by regulating Bax and Bcl-2 levels, however, it did not alter inflammatory mediators. Additionally, betaine improved serum potassium (K<sup>+</sup>) and blood urea nitrogen (BUN) levels, whereas it increased alanine aminotransferase (ALT) levels and impaired hematological parameters.<b>Conclusions:</b> Altogether, these data illustrated that betaine exhibits a gastroprotective effect against ulcers through the homocysteine pathway by modulating oxidative stress in the gastric tissue; however, its systemic effects should not be ignored.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 11-12","pages":"1806-1817"},"PeriodicalIF":1.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33480959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Prospective Multi-Institutional Evaluation of Iatrogenic Urethral Catheterization Injuries. 医源性导尿损伤的前瞻性多机构评估。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-10-01 DOI: 10.1080/08941939.2022.2109226
Stefanie M Croghan, Leah Hayes, Eabhann M O'Connor, Mark Rochester, William Finch, Anne Carrie, Shane W Considine, Frank D'Arcy, Aisling Nic An Riogh, Wasim Mahmalji, Mohammed Elhadi, Helen Thursby, Ian Pearce, Vaibhav Modgil, Hosam Noweir, Eoin MacCraith, Aideen Madden, Rustom Manecksha, Eva Browne, Subhasis K Giri, Connor V Cunnane, John Mulvihill, Michael T Walsh, Niall F Davis, Hugh D Flood
{"title":"A Prospective Multi-Institutional Evaluation of Iatrogenic Urethral Catheterization Injuries.","authors":"Stefanie M Croghan,&nbsp;Leah Hayes,&nbsp;Eabhann M O'Connor,&nbsp;Mark Rochester,&nbsp;William Finch,&nbsp;Anne Carrie,&nbsp;Shane W Considine,&nbsp;Frank D'Arcy,&nbsp;Aisling Nic An Riogh,&nbsp;Wasim Mahmalji,&nbsp;Mohammed Elhadi,&nbsp;Helen Thursby,&nbsp;Ian Pearce,&nbsp;Vaibhav Modgil,&nbsp;Hosam Noweir,&nbsp;Eoin MacCraith,&nbsp;Aideen Madden,&nbsp;Rustom Manecksha,&nbsp;Eva Browne,&nbsp;Subhasis K Giri,&nbsp;Connor V Cunnane,&nbsp;John Mulvihill,&nbsp;Michael T Walsh,&nbsp;Niall F Davis,&nbsp;Hugh D Flood","doi":"10.1080/08941939.2022.2109226","DOIUrl":"https://doi.org/10.1080/08941939.2022.2109226","url":null,"abstract":"<p><strong>Objectives: </strong>To perform a multi-institutional investigation of incidence and outcomes of urethral trauma sustained during attempted catheterization.</p><p><strong>Patients & methods: </strong>A prospective, multi-center study was conducted over a designated 3-4 month period, incorporating seven academic hospitals across the UK and Ireland. Cases of urethral trauma arising from attempted catheterization were recorded. Variables included sites of injury, management strategies and short-term clinical outcomes. The catheterization injury rate was calculated based on the estimated total number of catheterizations occurring in each center per month. Anonymised data were collated, evaluated and described.</p><p><strong>Results: </strong>Sixty-six urethral catheterization injuries were identified (7 centers; mean 3.43 months). The mean injury rate was 6.2 ± 3.8 per 1000 catheterizations (3.18-14.42/1000). All injured patients were male, mean age 76.1 ± 13.1 years. Urethral catheterization injuries occurred in multiple hospital/community settings, most commonly Emergency Departments (36%) and medical/surgical wards (30%). Urological intervention was required in 94.7% (54/57), with suprapubic catheterization required in 12.3% (n = 7). More than half of patients (55.56%) were discharged with an urethral catheter, fully or partially attributable to the urethral catheter injury. At least one further healthcare encounter on account of the injury was required for 90% of patients post-discharge.</p><p><strong>Conclusions: </strong>This is the largest study of its kind and confirms that iatrogenic urethral trauma is a recurring medical error seen universally across institutions, healthcare systems and countries. In addition, urethral catheter injury results in significant patient morbidity with a substantial financial burden to healthcare services. Future innovation to improve the safety of urinary catheterization is warranted.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 10","pages":"1761-1766"},"PeriodicalIF":1.9,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10671599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Recognizing and Managing Pancreaticopleural Fistulas in Children. 儿童胰胸膜瘘的识别和处理。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-09-01 Epub Date: 2022-07-24 DOI: 10.1080/08941939.2022.2103603
Konstantina Dimopoulou, Anastasia Dimopoulou, Nikolaos Koliakos, Andrianos Tzortzis, Dimitra Dimopoulou, Nikolaos Zavras
{"title":"Recognizing and Managing Pancreaticopleural Fistulas in Children.","authors":"Konstantina Dimopoulou,&nbsp;Anastasia Dimopoulou,&nbsp;Nikolaos Koliakos,&nbsp;Andrianos Tzortzis,&nbsp;Dimitra Dimopoulou,&nbsp;Nikolaos Zavras","doi":"10.1080/08941939.2022.2103603","DOIUrl":"https://doi.org/10.1080/08941939.2022.2103603","url":null,"abstract":"<p><p><b>Background:</b> Pancreaticopleural fistula, an abnormal communication between the pancreas and the pleural cavity, is a rare complication of pancreatic disease in children and is mainly associated with acute pancreatitis, chronic pancreatitis, trauma or iatrogenicinjury. The present review presents the current available data concerning the pathogenesis, clinical features, diagnosis and management of this unusual but difficult clinical problem among children, in order to shed light on its pathologic manifestation and raise clinical suspicion.<b>Methods:</b> The review of the literature was performed through a PubMed search of pediatric original articles and case reports, using the key words \"pancreaticopleural fistula\", \"pancreatitis\", \"pleural effusion\", \"pseudocyst\" and \"children\". The literature search revealed 47 cases of pediatric patients with pancreaticopleural fistula.<b>Results:</b> Diagnosis is based on the patient's medical history, physical examination and imaging, while the cornerstone of diagnosis is the presence of high pleural effusion amylase levels. The management of this disorder includes conservative, endoscopic and surgical treatment options. If treated promptly and properly, this clinical entity could have a lower rate of complications.<b>Conclusions:</b> The incidence of pancreaticopleural fistula in children may be underestimated in the literature, due to a reduced degree of clinical suspicion. A more heightened awareness of this entity is needed to improve the quality of life in children that suffer from this condition, as early diagnosis is essential for effective treatment and improved outcome.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 9","pages":"1704-1710"},"PeriodicalIF":1.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40623423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erector Spinae Plane Block versus Transversus Abdominis Plane Block for Postoperative Analgesia in Abdominal Surgery: A Systematic Review and Meta-Analysis. 竖脊肌平面阻滞与腹横平面阻滞对腹部手术术后镇痛的影响:系统回顾和荟萃分析。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-09-01 Epub Date: 2022-07-17 DOI: 10.1080/08941939.2022.2098426
Lin Liheng, Cai Siyuan, Cai Zhen, Wu Changxue
{"title":"Erector Spinae Plane Block versus Transversus Abdominis Plane Block for Postoperative Analgesia in Abdominal Surgery: A Systematic Review and Meta-Analysis.","authors":"Lin Liheng,&nbsp;Cai Siyuan,&nbsp;Cai Zhen,&nbsp;Wu Changxue","doi":"10.1080/08941939.2022.2098426","DOIUrl":"https://doi.org/10.1080/08941939.2022.2098426","url":null,"abstract":"<p><strong>Background: </strong>Regional anesthesia technique has been reported to exert excellent analgesic efficacy for various surgeries. Erector spinae plane block (ESPB) and transversus abdominis plane (TAP) block are good ways to relieve postoperative pain after abdominal surgery. However, the analgesic efficacy between them remains controversial. This meta-analysis evaluated the analgesic effect between these two blocks in abdominal surgery with statistical and clinical interpretation.</p><p><strong>Methods: </strong>PubMed, Web of Science, the Cochrane Library, ClinicalTrials.gov register, and Embase databases were systematically searched by two independent investigators from the inception to December 2021.</p><p><strong>Results: </strong>10 randomized controlled trials (RCTs) comprising 570 patients were included in the final meta-analysis. Meta-analysis revealed that ESPB decreased the opioid consumption and improved the pain scores during the first 24 postoperative hours compared with TAP groups statistically, while the magnitude of this difference did not reach the clinically significant threshold (10 mg of intravenous morphine consumption and 1.3 cm on the VAS scale). In addition, ESPB prolonged blockade duration and decreased the occurrence of postoperative nausea and vomiting (PONV). However, it did not improve the patients' satisfaction.</p><p><strong>Conclusions: </strong>Although ESPB does not provide better clinical analgesia than the TAP block, it could be a comparable nerve block technique for abdominal wall analgesia.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 9","pages":"1711-1722"},"PeriodicalIF":1.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Near-Infrared Autofluorescence Imaging in Thyroid Surgery: A Systematic Review and Meta-Analysis. 近红外自体荧光成像在甲状腺手术中的应用:一项系统综述和荟萃分析。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-09-01 Epub Date: 2022-07-03 DOI: 10.1080/08941939.2022.2095468
Wei Lu, Qiang Chen, Pei Zhang, Anping Su, Jingqiang Zhu
{"title":"Near-Infrared Autofluorescence Imaging in Thyroid Surgery: A Systematic Review and Meta-Analysis.","authors":"Wei Lu,&nbsp;Qiang Chen,&nbsp;Pei Zhang,&nbsp;Anping Su,&nbsp;Jingqiang Zhu","doi":"10.1080/08941939.2022.2095468","DOIUrl":"https://doi.org/10.1080/08941939.2022.2095468","url":null,"abstract":"<p><strong>Objective: </strong>This meta-analysis aimed to assess the position of near-infrared autofluorescence (NIRAF) imaging in the recognition and protection of the parathyroid gland (PG) during thyroidectomy.</p><p><strong>Methods: </strong>The PubMed, MEDLINE, EMBASE, Web of Science, and Cochrane Library databases were searched up to June 2021. The primary outcome was to evaluate the rates of postoperative hypocalcemia, inadvertent PG resection, and autotransplantation of PG when adopting NIRAF imaging compared with standard naked-eye (N-E) surgery.</p><p><strong>Results: </strong>Eight studies with 2,889 patients were enrolled in the analysis. Our analysis showed that the incidence of transient hypocalcemia was 7.11% (60/844) in the NIRAF group and 22.40% (458/2045) in the N-E group (<i>p</i> < 0.0001) and the rate of transient hypoparathyroidism was 28.31% (126/445) and 33.36% (496/1487) in the NIRAF and N-E groups (<i>p</i> = 0.0008). The rate of inadvertent resection of PGs was 7.65% (55/719) in the NIRAF group and 14.39% (132/917) in the N-E group (<i>p</i> < 0.0001). No significant difference was observed in other indexes including the pooled proportion of permanent hypocalcemia and rate of PG autotransplantation.</p><p><strong>Conclusions: </strong>The application of NIRAF imaging in thyroidectomy can help lower the incidence of inadvertent PG resection and reduce the risk of postoperative hypocalcemia and hypoparathyroidism compared with N-E recognition.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 9","pages":"1723-1732"},"PeriodicalIF":1.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The Comparison of Postoperative Analgesic Efficacy of Ultrasound-Guided Paravertebral Block and Mid-Point Transverse Process Pleura Block in Mastectomy Surgeries: A Randomized Study. 超声引导椎旁阻滞与胸膜横突中点阻滞在乳房切除术术后镇痛效果的比较:一项随机研究。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-09-01 Epub Date: 2022-07-17 DOI: 10.1080/08941939.2022.2098544
Agâh Abdullah Kahramanlar, Mehmet Aksoy, Ilker Ince, Aysenur Dostbıl, Erdem Karadenız
{"title":"The Comparison of Postoperative Analgesic Efficacy of Ultrasound-Guided Paravertebral Block and Mid-Point Transverse Process Pleura Block in Mastectomy Surgeries: A Randomized Study.","authors":"Agâh Abdullah Kahramanlar,&nbsp;Mehmet Aksoy,&nbsp;Ilker Ince,&nbsp;Aysenur Dostbıl,&nbsp;Erdem Karadenız","doi":"10.1080/08941939.2022.2098544","DOIUrl":"https://doi.org/10.1080/08941939.2022.2098544","url":null,"abstract":"<p><strong>Purpose/aim of the study: </strong>The purpose of this triple-blind randomized study is to compare the postoperative analgesic efficacy of Mid-Point Transverse Process Pleura Block (MTP) and Paravertebral Block (PVB) in patients undergoing breast surgery.</p><p><strong>Materials and methods: </strong>The study was retrospectively registered on ClinicalTrials.gov (NCT05332028). A total of 64 patients undergoing unilateral simple mastectomy operation due to breast cancer were included in the study. Before the anesthesia procedure, participants were randomly assigned to one of two groups: Group 1: Participants undergoing PVB or Group 2: Participants undergoing MTP block. All block applications were performed using 20 mL of 0.25% bupivacaine. Routine general anesthesia protocol was performed on all patients. In the postanesthetic care unit, fentanyl infusion was given to all patients postoperatively via a patient-controlled analgesia device. Postoperative fentanyl consumption, time to the first request for analgesia, VAS score values at rest and in motion, and blocked dermatome areas were recorded.</p><p><strong>Results: </strong>Postoperative total opioid consumption, the number of patients given rescue analgesia, the time requiring postoperative supplemental analgesia, postoperative pain scores at rest and in motion, and blocked dermatome areas at both anterior and posterior lower and upper limits were not different between groups (<i>p</i> > 0.05, for all).</p><p><strong>Conclusions: </strong>It was concluded that ultrasound-guided PVB and MTP blocks have similar postoperative analgesic efficacy in patients undergoing breast surgery. The MTP block may be preferred as an alternative to PVB for breast surgeries with less risk of complications.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 9","pages":"1694-1699"},"PeriodicalIF":1.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40601829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Three-Dimensional in Vivo Anatomical Study of Female Iliac Vein Variations. 女性髂静脉变异的三维体内解剖研究。
IF 1.9 4区 医学
Journal of Investigative Surgery Pub Date : 2022-09-01 Epub Date: 2022-07-06 DOI: 10.1080/08941939.2022.2095469
Wenling Zhang, Chunlin Chen, Guidong Su, Hui Duan, Zhiqiang Li, Ping Shen, Jiaxin Fu, Ping Liu
{"title":"Three-Dimensional in Vivo Anatomical Study of Female Iliac Vein Variations.","authors":"Wenling Zhang,&nbsp;Chunlin Chen,&nbsp;Guidong Su,&nbsp;Hui Duan,&nbsp;Zhiqiang Li,&nbsp;Ping Shen,&nbsp;Jiaxin Fu,&nbsp;Ping Liu","doi":"10.1080/08941939.2022.2095469","DOIUrl":"https://doi.org/10.1080/08941939.2022.2095469","url":null,"abstract":"<p><strong>Objective: </strong>To investigate female iliac vein variations by using the computed tomography angiography (CTA) three-dimensional (3 D) reconstruction technique.</p><p><strong>Methods: </strong>We retrospectively studied 1623 patients undergoing abdominal and pelvic CTA scanning for gynecological diseases from December 2009 to December 2018. Accurate digital 3 D models of the iliac vein were constructed using Mimics 19.0 software and used to study the morphology and variations. Variations in the common iliac vein (CIV), external iliac vein (EIV) and internal iliac vein (IIV) were classified as type I, abnormal number of veins; type II, abnormal communicating branches; or type III, other variations.</p><p><strong>Results: </strong>The overall variation rates of the iliac vein and CIV were 51.57% (837/1623) and 20.33% (330/1623), respectively. The main type of CIV variation was type II. The main type I CIV variation was the absence of the CIV (98.15%), which mostly occurred on the right side (64.81%, 35/54). Type II CIV variation was the most common, with abnormal communicating branches between the left CIV and right IIV (81.78%, 211/258). The overall variation rates of the EIV and IIV were 36.66% (595/1623) and 49.60% (805/1623), respectively, mainly on the right side. The main type of variation was type I. Among them, the division of the IIV into two branches plus convergence with the ipsilateral EIV was the most common (22.98%, 373/1623).</p><p><strong>Conclusion: </strong>In this study, approximately half of the patients had iliac vein variations. The preoperative identification of iliac vein variation may reduce vascular injury in pelvic surgery.</p>","PeriodicalId":16200,"journal":{"name":"Journal of Investigative Surgery","volume":"35 9","pages":"1679-1685"},"PeriodicalIF":1.9,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40476097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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