{"title":"Unlocking Healing Potential: Impact of Non-Surgical Therapy on Peri-Implant Crevicular Fluid Calprotectin Levels - A Clinical Insight.","authors":"Ritvija Cinderella, Arvina Rajasekar","doi":"10.1615/JLongTermEffMedImplants.2025057382","DOIUrl":"10.1615/JLongTermEffMedImplants.2025057382","url":null,"abstract":"<p><p>Biomarkers within peri-implant crevicular fluid (PICF) are emerging as pivotal diagnostic agents, promising heightened accuracy in identifying peri-implant diseases. The present study aimed to assess the impact of non-sur-gical therapy on PICF calprotectin levels in patients with peri-implantitis. A total of 40 individuals aged between 30 and 60 years were enrolled: Group I (n = 20 healthy peri-implant sites) and Group IIa (n = 20 peri-implantitis sites). Clinical parameters such as peri-implant probing depth (PPD) and clinical attachment level (CAL) were recorded. PICF samples were collected and assayed for calprotectin using enzyme-linked immunosorbent assay (ELISA). After clinical examination and PICF collection at baseline, mechanical debridement was done for peri-implantitis patients, and after 3 months, clinical examination and PICF collection was done (Group IIb). The results were statistically analyzed. The PICF calprotectin level was higher in Group IIa (43.76 ± 3.64 ng/mL) as compared with Group I (11.36 ±2.53 ng/mL). Between Groups IIa and IIb, there was a significant reduction in PPD, CAL, and calprotectin from baseline to 3 months (P < 0.05). Pearson correlation in Groups IIa and IIb revealed that the correlation between calprotectin and clinical parameters was strongly positive and statistically significant. The present study suggests that there was a significant reduction in PICF calprotectin levels among peri-implantitis patients after mechanical debridement. Also, there exists a positive correlation between PICF calprotectin and peri-implant health parameters.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 4","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145489101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Prolene Mesh in the Treatment of Traumatic Midface Fractures.","authors":"Sujeeth Kumar Shetty, Suprathima Saritha R, Sathish Radhakrishna","doi":"10.1615/JLongTermEffMedImplants.2025054281","DOIUrl":"10.1615/JLongTermEffMedImplants.2025054281","url":null,"abstract":"<p><p>Midface fractures constitute a severe medical challenge due to their intricacy, incidence, and socioeconomic implications. The orbit and the maxillary sinus are the most prominent parts of the face and form the most common site of fracture. Reconstruction of these frequently observed fractures is necessary. The uses of polypropylene (prolene) mesh are numerous in general surgery, so its use and effects in the maxillofacial region can be explored. The aim was to evaluate the efficacy of prolene mesh in treating defects in the midface due to trauma, especially the orbital floor and anterior wall of the maxillary sinus. This was an observational study of 15 patients with midface fractures who had undergone reconstruction with prolene mesh for orbital floor and anterior maxillary sinus wall defects. Data collected included gender, age, type of fracture, clinical parameters (e.g., postoperative tenderness at the surgical site, infraorbital paresthesia, diplopia, pus discharge, and extrusion of graft), and radiological assessment for sinus and/or orbital floor continuity and bone formation. Regular follow-ups were done at 1 week and 1, 3, and 6 months. Among the 15 patients studied, all were males with a mean age of 30 years. The clinical assessment revealed positive functional outcomes. Radiographic assessment with postoperative CT scans at 6 months showed sinus wall and/or orbital floor continuity and bone formation. The study concluded that, with proper case selection, prolene mesh is a safe and reliable option in the reconstruction of the anterior maxillary sinus wall and orbital floor.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathaniel J Starcher, Daniel T DeGenova, Matthew T Glazier, Klay B Miller, Peter Spencer, Vishvam Mehta, Nick Blair, Mallory Faherty, Benjamin C Taylor
{"title":"Accuracy of Preoperative Planning Helical Blade Length during Treatment of Intertrochanteric Hip Fractures with Trochanteric Fixation Nail System.","authors":"Nathaniel J Starcher, Daniel T DeGenova, Matthew T Glazier, Klay B Miller, Peter Spencer, Vishvam Mehta, Nick Blair, Mallory Faherty, Benjamin C Taylor","doi":"10.1615/JLongTermEffMedImplants.2025055402","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025055402","url":null,"abstract":"<p><p>Intertrochanteric hip fractures are commonly treated with cephalomedullary nailing. One time-consuming aspect of the procedure is intraoperatively measuring the helical blade length. This investigation sought to determine if preoperative imaging can be reliably used to predict helical blade length and therefore reduce operative time accurately. This was a single-center, single-surgeon retrospective chart review. All subjects were operated on by the senior author at a single urban level-1 trauma center. Each patient underwent cephalomedullary nailing using a helical blade. The medical records were reviewed for demographic, imaging, and operative data. Two raters preoperatively recorded head element length, subsequently estimated helical blade implant sizes, and actual implant length used intraoperatively. In total, 134 patients were analyzed. The results demonstrated that radiographs (R2 = 0.337, p < 0.001) and computed tomography (CT) imaging (R2 ≥ 0.435, p < 0.001) could not reliably predict helical blade length, and that radiographs were more accurate than CT scans in predicting actual implant size (p < 0.001). Preoperative imaging modalities predicted the exact size only 23.8% of the time using radiographs and 17.2% of the time using CT. Preoperative helical blade implant size was estimated accurately 24% of the time. However, raters were successful in estimating the length of the helical blade within three sizes. We demonstrate that preoperative imaging modalities are unable to accurately predict helical blade length.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"45-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling Alpha Amylase Dynamics in Peri-Implant Crevicular Fluid: A Comparative Analysis across Peri-Implant Health and Disease Spectrums.","authors":"Ritvija Cinderella, Arvina Rajasekar","doi":"10.1615/JLongTermEffMedImplants.2025056747","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025056747","url":null,"abstract":"<p><p>This study aimed to evaluate the levels of alpha amylase in patients with healthy dental implants, peri-implant mucositis, and peri-implantitis. A cross-sectional study was conducted involving 75 implant sites, divided into three groups of 25: peri-implant health, peri-implant mucositis, and peri-implantitis. Peri-implant crevicular fluid was collected from each selected implant site and analyzed for alpha amylase levels using an ELISA kit. The resulting alpha amylase concentrations were statistically compared between the groups. The mean concentration of alpha amylase was lowest in healthy sites (9.57 ± 1.59 ng/mL), compared with peri-implant mucositis (14.90 ± 2.62 ng/mL) and peri-implantitis (20.67 ± 4.55 ng/mL), with the differences being statistically significant (P = 0.00). Furthermore, multiple comparisons revealed a statistically significant distinction between the groups (P = 0.000). Elevated levels of alpha amylase in peri-implant disease sites, as opposed to healthy sites, suggest its potential as a predictive marker for peri-implant diseases.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"91-96"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intramedullary Fixation of Tibial, Femoral, and Humeral Fractures Using an Expandable Nail: Case Series and Systematic Review of the Existing Literature.","authors":"Stamatios A Papadakis, Margarita- Michaela Ampadiotaki, Dimitrios Pallis, Labrini Agapitou, Stavros Lykos, Konstantinos Tsivelekas, Spyridon Galanakos","doi":"10.1615/JLongTermEffMedImplants.2025055433","DOIUrl":"10.1615/JLongTermEffMedImplants.2025055433","url":null,"abstract":"<p><p>Intramedullary nail is the gold standard for treating long bones diaphysial fractures. Although the Fixion nail (Disc-O-Tech Medical Technologies Ltd., Herzliya, Israel) is an alternative technique to this method which constitutes an expandable nail, which is used to gain surgical time due to the absence of locking screws. In our department, 28 patients with tibial, femoral and humeral shaft fractures were treated by the expandable nail system for 18 months. Operative time, radiation exposure and healing time were recorded. Follow-up was obtained for a minimum of 1 year with an average of 14 months. Furthermore, in this study, we demonstrated a systematic review of the existing literature regarding the outcomes of studies on the use of the Fixion nail. In our case series, we observed one pseudarthrosis of a femoral fracture treated with a retrograde nail and two infections in tibia's fractures. In two cases, during the nail insertion, we had a failure of the implant (deformation of the tip (apex) of the nail) and two cases with delayed unions. The average operating time was 30 min (range, 26-34 min) for the tibia, 45 (range, 35-50 min) for the femur, and 20 min (range, 15-25 min) for the humerus. The radiation exposure was 0.20-0.50 s. During the systematic review, 25 studies and 790 patients with fractures of the femur, tibia and humerus were included, that met the inclusion and exclusion criteria. The mean age was 37.8 years, the time for union was 26 weeks, and 33 nonunions were observed. This study demonstrates satisfactory healing and alignment for treating tibial, femoral and humeral shaft fractures using this device. The main advantages of the expandable nail are minimal exposure to radiation and shorter operating time due to the lack of transverse locking.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"77-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"To Determine Influence of Drill Shape on the Primary Stability of the Implant: An In Vitro Pilot Study.","authors":"Prajna Shetty, Ramesh Chowdhary, Pooja P Shetty","doi":"10.1615/JLongTermEffMedImplants.2025057857","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025057857","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated whether drill shape and bone preparation influences the primary stability of the implant using resonance frequency analysis and insertion torque values.</p><p><strong>Materials and methodology: </strong>In this study, four most common, commercially available drill systems were used in this study. Bovine bone was chosen for the study. All the implants were chosen of the same dimension (3.5 mm ȕ 13 mm) to avoid bias and error. For convenience the study was divided into two parts. Part I of the study included performing osteotomy per manufacturer's instructions with a variability in the speed of the drilling at 300 rpm and 800 rpm, respectively. All the implants were placed at bone level, which was checked by taking radiographs. The primary stability of the implants of all the four different companies were measured using an ISQ machine (Penguin, Sweden). Part II of the study involved single drilling kit for the study. Sequential drilling protocol is selected for the second part of the study. All the four-implant system are placed using the same set of drill system. The implants are placed at 300 rpm. ISQ values are recorded using RFA machine (Penguin, Sweden) for each implant. IOPA was also recorded for the study.</p><p><strong>Results: </strong>The results were subjected to analysis.</p><p><strong>Conclusion: </strong>The results of this study suggest that implant drill shape did not have any significant effect on the overall primary stability of the implant. However, in certain implants, due to their unique design, custom drilling kits might be more feasible to use.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation of a Carrageenan and Fucoidan Silica Nanoparticle-Based Membrane for Guided Bone Regeneration in Dental Implant Sites.","authors":"L Akshayaa, Balaji S Ganesh","doi":"10.1615/JLongTermEffMedImplants.2024049789","DOIUrl":"10.1615/JLongTermEffMedImplants.2024049789","url":null,"abstract":"<p><p>Carrageenans are the sulfated polysaccharides, extracted from the extracellular matrix of red seaweeds. Peri-implantitis is a pathological condition occurring in tissues around dental implants. Management of peri-implantitis should be concerned with control of infection, detoxification of the implant site and regeneration of alveolar bone. The goal of our study was to develop a membrane infused with carrageenan and fucoidan silica nanoparticles for guided bone regeneration around implant sites. Carrageenan (2%) was boiled for 2 min and 5% of fucoidan were added and boiled at 60°C and further 4000 μL of PEG was added, then film casting of membrane was done. 10 ml of silica nanoparticles were mixed in 0.1 g of SiO2 nanoparticles and were added to prepared carrageenan and fucoidan solution. Then film casting was done and air dried for 24 h. Antimicrobial assay, antioxidant activity, swelling and degradation analysis, FTIR test, tensile strength testing and SEM analysis were performed. The antimicrobial effect of carrageenan membrane showed better inhibitory effect against Streptococcus mutans. Antioxidant activity of the membrane infused with carrageenan and fucoidan silica nanoparticles shows 52.93 ± 0.35 SC effect percentage. The maximum force of tensile stress at break for carrageenan fucoidan incorporated with silica nanoparticles was about 5.76 MPa and for control sample membrane was 4.34 Mpa. Carrageenan and fucoidan based silica nanoparticles developed membrane showed good tensile strength and proven to have better antimicrobial, antioxidant activity with water absorption capacity which can be effectively used for guided bone regeneration around implant sites.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Metallurgical Composition of Commercially Available Dental Implant Drills and Its Influence on Corrosion Resistance: An In Vitro Study.","authors":"Ramakrishna Harigopal, Ramesh Chowdhary","doi":"10.1615/JLongTermEffMedImplants.2024047254","DOIUrl":"10.1615/JLongTermEffMedImplants.2024047254","url":null,"abstract":"<p><p>The objective of this in vitro study was to evaluate the elemental composition of commercially available dental implant drills using the positive material identification testing (PMI), its influence on corrosion resistance and longevity. Three implant drills each from 5 different implant systems (Groups I to V) were included in the study. Positive material identification testing, a technique of non-destructive testing using X-ray diffraction was carried out to evaluate the elemental composition of each drill system in percentage and grade testing of the alloy used for manufacturing the drills. Groups I and II had the maximum Chromium content of 17.09%Cr and 16.09%Cr. Group IV had a minimum of 11.67%Cr. Nickel content was maximum in Group III. Groups I and II belonged to Ferritic stainless steel alloys while Groups III, IV, and V were Martensitic stainless steel alloys. Ferritic stainless steel alloy drills (Groups I and II) were vulnerable to corrosion and wear compared to Martensitic stainless steel alloy drills (Groups III, IV, and V) with repeated surgical use. Incorporation of newer elements in stainless steel alloys is essential to promote corrosion resistance and drill longevity.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"41-45"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the Impact of Surface Treatments: A Prospective Analysis of Clinical and Radiographic Outcomes in Dental Implant Patients.","authors":"Arvina Rajasekar","doi":"10.1615/JLongTermEffMedImplants.2024051955","DOIUrl":"10.1615/JLongTermEffMedImplants.2024051955","url":null,"abstract":"<p><p>Implant dentistry is a widely utilized treatment approach for fully or partially edentulous patients. To enhance the success rates of dental implants, various surface modifications have been developed. This study aimed to compare clinical and radiographic parameters in patients with sandblasted acid-etched versus anodized surface dental implants. In this prospective clinical study, 78 patients who had undergone implant placement for missing single posterior tooth in mandible using sandblasted acid-etched and anodized surface dental implants during August 2019-December 2019 were enrolled according to strict inclusion and exclusion criteria and were categorized into Group 1: SLA (n = 27), Group 2: SLActive (n = 26), Group 3: TiUnite (n = 25) based on the surface modification of the implants. Peri-implant probing depth (PPD) and crestal bone loss (CBL) measurements were carried out at 3 months and 1-year intervals. For intergroup comparison, one-way ANOVA and Tukey's HSD post hoc test were used. For intragroup comparison, paired t test was used. PPD and CBL in Group 3 implants was significantly higher than Groups 1 and 2 (P ≤ 0.05). On pairwise comparison, there was a statistically significant difference in PPD and CBL between the groups at baseline (P ≤ 0.05) and 1-year follow-up (P ≤ 0.05) except for Group 1 vs. Group 2 at 1-year follow-up (P > 0.05). Intragroup comparison of PPD and CBL showed that there was a statistically significant difference from baseline in all the three groups in terms of PPD (P ≤ 0.05) and CBL (P ≤ 0.05). Patients with anodized dental implants exhibited greater PPD and CBL compared with those with sandblasted acid-etched implants.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"7-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vidit Chirimar, Anshul Trivedi, Deepesh Saxena, Roma Goswami
{"title":"Comparative Analysis of Different Implant Macrogeometry for Improved Esthetics, Inverted Body Shift, and Reverse Neck Collar Implant with Conventional Tapered Implant: A 3D Finite Element Analysis Study.","authors":"Vidit Chirimar, Anshul Trivedi, Deepesh Saxena, Roma Goswami","doi":"10.1615/JLongTermEffMedImplants.2025055404","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025055404","url":null,"abstract":"<p><p>The effect of different implant macrogeometry varying in shape along with the biomechanical effect of reduced buccal cortical bone thickness has not been studied and compared in the literature. The purpose of this finite element analysis (FEA) is to understand the stress distribution on the surrounding cortical bone for implants specially designed for use in anterior maxillary region and compare them with the conventional tapered (CT) implants. Also to assess the advantage of these implants in compromised buccal bone conditions. Two 3D FEA bone block in the maxillary anterior region were meshed with D3 type of bone. One block with uniform cortical bone thickness all around whereas other with reduced buccal cortical bone. Three different implant, inverted body shift (INB) (4.5*3.8*13), reverse neck collar (4.5*4.2*13) and CT implant (4.5*13). Each design was meshed into the different bone blocks creating total of six meshed models. An oblique load of 178 N from palatal side in the buccopalatal direction was applied. INB implant showed the best performance in terms of minimum stress concentration on the surrounding buccal bone specially in the reduced buccal cortical plate situation. The CT implant showed highest percentage increase in stress concentration on reducing buccal plate thickness. The new implant designs specially designed for maxillary anterior region where sufficient buccal bone is often lacking proved to be advantageous in such conditions due to the possibility of additional bone formation around the implant. With its high stability it should be preferred for use in compromised conditions.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}