Journal of long-term effects of medical implants最新文献

{"title":"The Use of Shape-Memory Alloy Staples (Nitinol) in the Treatment of Pubic Symphyseal Disruptions: Clinical Results and Radiographic Outcomes.","authors":"Braden J Passias,&nbsp;John J Verre,&nbsp;Kyle McGrath,&nbsp;Daniel T DeGenova,&nbsp;Benjamin C Taylor","doi":"10.1615/JLongTermEffMedImplants.2022043658","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022043658","url":null,"abstract":"<p><p>Nitinol is a shape-memory alloy that has many diverse applications in the field of orthopedics. There have been no previous investigations reporting clinical or radiographic outcomes of the use of nitinol staples in the definitive stabilization of the pubic symphysis. A retrospective chart review was completed on 42 patients who underwent operative stabilization of pubic symphyseal disruption at an urban level-1 trauma center. Patients treated with pelvic staples alone, or in conjunction with traditional plates and screws, were compared with those treated without the use of a shape memory alloys. Thirty-four patients were included for final analysis (8 staples and 26 controls) in this investigation. Three of eight patients in the pelvic staple group had implant failures, with two having a loss of reduction (25%); this was not significantly different from the seven hardware failures (P = 0.61) seen in the control group without any loss of reduction (P = 0.17). Failures in the nitinol staple group occurred earlier at 17.3 days compared with the control group at 101.7 days (P = 0.003). There were no significant differences between groups with regards to any of the other pre- or postoperative variables investigated. The use of nitinol staples vs. traditional plate and screw constructs for stabilizing the pubic symphysis did not result in more clinical failures. The hardware failures identified in the nitinol staple group occurred significantly earlier in the postoperative period, and were associated with a loss of reduction of the pubic symphysis.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"33 1","pages":"67-74"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10801641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is CT-A Always Reliable in Detecting Active Bleeding in Closed Pelvic Fractures? Management of a Case with Multiple Closed Pelvic Fratures and Internal Iliac Artery Bleeding.","authors":"Anastasia Vasilopoulou,&nbsp;Vasileios Mamalis,&nbsp;Spyridon J Maris,&nbsp;Emmanouel Antonogiannakis,&nbsp;Iakovos Roupinas,&nbsp;Stavros Angelis,&nbsp;Stamatios Kyriakopoulos,&nbsp;Antonios Tsanis,&nbsp;Alexandros P Apostolopoulos","doi":"10.1615/JLongTermEffMedImplants.2022042027","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022042027","url":null,"abstract":"<p><p>One of the most important complications of pelvic injuries is hemorrhage which can be attributed to the venus plexus of the pelvis, the damaged bone on the fracture site, or in 15% of cases to arterial cause. In the last case mortality could reach 70%. Clinical case presentation, a 77-year-old man, presented in the emergency department of our hospital hemodynamically unstable due to fall from height (3 meters) with comminuted bilateral fractures of the pubic rami, right sacral and iliac wing fracture, right acetabular fracture, fractures of transverse processes of the first, second, and fifth lumbar spine vertebrae and a periprothetic fracture of the right femur. Advanced trauma life support (ATLS) protocol was followed throughout. Computed tomography (CT) scans and CT angiography performed, showed the above mentioned pelvic fractures that did not require stabilization, without further injuries, and a well described retroperitoneal hematoma without any evidence of active bleeding. During the resuscitation process the patient developed cardiac arrest and cardiopulmonary resuscitation (CPR) protocol was followed. The patient was intubated and retained his cardiac rhythm. However, he remained unstable and an angiography was then performed that revealed internal iliac artery bleeding and embolism of the internal iliac artery was performed. The patient was stabilized and was transferred to the intensive care unit for further management. Arterial hemorrhage due to pelvic injury is less common, however presents with high rates of mortality. CT angiography may in some cases not reveal existing active bleeding, misleading the clinician. Therefore, in patients with high clinical suspicion of arterial pelvic hemorrhage who remain unstable during the initial resuscitation and do not present with other primary source of bleeding, an angiography and embolism should be performed as soon as possible.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 4","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33438403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Marginal and Internal Fit at Implant-Abutment Interface of Original and Compatible Nonoriginal Abutments.","authors":"Antoine Berberi,&nbsp;Georges Tehini,&nbsp;Bouchra Hjeij,&nbsp;Georges Aoun","doi":"10.1615/JLongTermEffMedImplants.2022040297","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022040297","url":null,"abstract":"<p><p>Is to measure the peripheral and internal gap at the implant-abutment interface of an implant system connected to its original or compatible non-original abutments. Twenty implants were assembled with four different types of abutments having the same conical internal interface. All abutments were considered compatible with Tx Astra Tech Implant SystemTM. Four groups were created and each group of five implants was connected to a different abutment; Ti DesignTM abutments (group A), DualTM abutments (group B), Natea plusTM abutments (group C) and ImplanetTM abutments (group D). The peripheral gaps between implant and abutment were observed in three points facing the flat surface of the abutment. The implant-abutment assemblies were then embedded in resin and grinded in the mesio-distal direction of the scalloped abutment margin using a diamond disk at very low speed and under water-cooling. The inner aspect of the implant abutment interface was observed in three different points, on the coronal border of the connection, in the middle area and on the apical border of the implant-abutment interface. The mean gap width was 0.543 ± 0.09 μm for group A and, respectively, 0.708 ± 0.1232 μm, 0.726 ± 0.0891 μm and 0.818 ± 0.0851 μm for groups B, C and D. When comparing group, A to B and C, a highly significant difference in numbers was obvious while an even higher variation was observed with group D. External and internal fit of components is better when using original components.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 3","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40417043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avoiding Complications of Locking Plating for Proximal Humerus Fractures.","authors":"Zinon T Kokkalis,&nbsp;Efstratios Papanikos,&nbsp;Ekaterini Bavelou,&nbsp;Andreas Panagopoulos,&nbsp;Panagiotis Megas","doi":"10.1615/JLongTermEffMedImplants.2022040229","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022040229","url":null,"abstract":"<p><p>Proximal humeral fractures are very common, especially among elderly people with osteoporosis. The treatment methods are numerous, according to the characteristics of the patient and the fracture, as well as the surgeon's preference. These fractures can be treated either conservatively or operatively with closed or open reduction and internal fixation, or arthroplasty. During the past decades, with the advances in osteosynthesis and the establishment of locking plates, many surgeons prefer managing humeral fractures with open reduction and internal fixation with locking plates. Even though this is a widespread method of treatment, many studies report high complication rates, including perioperative and hardware complications. This article presents the most common complications a surgeon may face when managing this kind of fractures, as well as intraoperative techniques that can be used to avoid them.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 3","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40716832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher Infection Rate after ACL Reconstruction with Hamstrings Tendon Autografts Compared with Bone Patellar Bone Tendon Autografts: A Review.","authors":"Jim D Georgoulis,&nbsp;Andreas F Mavrogenis,&nbsp;Ioannis Gkiatas,&nbsp;Christos N Chatzipapas,&nbsp;Dimitrios Koulalis,&nbsp;Dimitrios Mastrokalos,&nbsp;Michael Elias Hantes,&nbsp;Anastasios D Georgoulis","doi":"10.1615/JLongTermEffMedImplants.2022041978","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022041978","url":null,"abstract":"<p><p>Infection after anterior cruciate ligament reconstruction is a rare but devastating complication resulting in a deleterious impact on knee function as well as an increased related cost for treatment and rehabilitation for the patients. There are conflicting reports regarding the rate of infection between bone patellar tendon bone (BPTB) and hamstrings tendon (HT) autografts for anterior cruciate ligament reconstruction. Therefore, we performed this review to summarize all the available data regarding the risk of infection after ACL reconstruction, to provide insight on the infection risk between BPTB and HT autografts, and to discuss current recommendations for the diagnosis and treatment of these infections. The incidence and risk of infection after ACL reconstruction with HT graft is higher compared with BPTB grafts. The most commonly subacute and late infections, quadruple type, need for cannulated instruments for harvesting, size and shape and fixation of the extra-tunnel material of the HT are important risk factors for infection. Combined antibiotics administration and adequate arthroscopic lavage and debridement are the optimal treatments for ACL reconstruction infection. Early diagnosis and treatment is the most important predictor for graft retention, which accounts more commonly for BPTB grafts. The treating physicians should be aware of the higher incidence of infection after ACL reconstruction with HT graft, as well as for the need for a high clinical suspicion for early diagnosis of the infection. These will increase the possibility of eradication of the infection and retention of the graft.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 3","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40417041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Lumbar Paravertebral Space Ultrasound Lumbar Plexus Block Technique for Hip Fracture Surgery in the Elderly.","authors":"Theodosios Saranteas,&nbsp;Rizos Souvatzoglou,&nbsp;Andreas Kostroglou,&nbsp;Spyridon Sioutis,&nbsp;Kalliopi Christodoulaki,&nbsp;Dimitrios Koulalis,&nbsp;Eleftheria Soulioti,&nbsp;Thomas Papadimos,&nbsp;Andreas F Mavrogenis","doi":"10.1615/JLongTermEffMedImplants.2022042501","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022042501","url":null,"abstract":"<p><p>Ultrasound imaging of peripheral nerves is challenging in elderly population. In cases involving the lumbar plexus (LP), we have employed ultrasound imaging and neurostimulation guidance for successful localization and block of the LP. The postero-medial segment of the psoas muscle (PSM), superior to the vertebral body and anterior to the transverse process (\"corner pocket\") was used as an imaging landmark for the implementation of the LP block. By advancing the needle through the lateral abdominal wall into the \"corner pocket\" we were afforded a seamless advancement of the needle into the postero-medial segment of the PSM, which is the standard anatomic position of LP in the PSM. Forty-eight patients in whom ultrasound imaging of the LP was not feasible, but the \"corner pocket\" was clearly depicted were included in the study. LP block characteristics and adverse events were recorded. The LP was localized in 43/48 patients. The average imaging, needling, and performance times to complete the block were 51 sec (range, 6-180 sec), 81 sec (range, 16-236 sec), and 132 sec (range, 24-270 sec), respectively. The median number of needle redirections per patient was 5.5 (range, 1-13). The local anesthetic spread was visualized in the postero-medial segment of the PSM in 39/43 patients. No complications were recorded. The imaging, needling, and performance times, as well as the number of needle passes did not significantly differ between obese and non-obese patients. In conclusion, in cases with challenging ultrasound imaging of the LP, ultrasound-assisted LP block can be accomplished through the lateral abdominal wall by using as an imaging landmark the \"corner pocket\" at the postero-medial quadrant of the PSM.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 3","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40716831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Enamel Matrix Derivative and N-Acetyl Cysteine on Proliferation and Osteogenic Activity of Dental Pulp Stem Cells.","authors":"R. Amid, Mina Iranparvar Alamdari, M. Kadkhodazadeh","doi":"10.1615/jlongtermeffmedimplants.2022040074","DOIUrl":"https://doi.org/10.1615/jlongtermeffmedimplants.2022040074","url":null,"abstract":"Successful bone regeneration often requires induction by signaling molecules. Enamel matrix derivative (EMD) is said to enhance initial phases of healing. N-acetyl cysteine (NAC) is a molecule assumed to enhance osteogenesis and induce osteoblastic differentiation. This study sought to compare effects of EMD and NAC on proliferation, mineralization, and enzymatic activity of dental pulp mesenchymal stem cells (DPSCs). DPSCs were cultured on mineralized bone allograft (MBA) powder. After 24 hours, EMD in concentrations of 10, 50, and 100 μg/mL and NAC in 5 mM concentration were added. Methyl thiazolyl tetrazolium (MTT) assay was used for cell proliferation assessment at 1, 2, and 3 days. Osteoblastic differentiation of DPSCs was evaluated at 30 days, by alizarin red staining and assessment of alkaline phosphatase (ALP) activity. Both EMD and NAC caused time-dependent reduction of cell proliferation compared with the negative control. Maximum proliferation of DPSCs was observed in the 10 μg/mL EMD group at all time points, whereas NAC caused higher ALP activity and mineralization of DPSCs compared with EMD. In vitro application of NAC, as a signaling molecule, may effectively enhance bone regeneration by the induction of mineralization and enzymatic activity, despite the resultant reduction in cell proliferation rate.","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 2 1","pages":"51-59"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67611541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Inferior Alveolar Nerve Position at the Region of First and Second Mandibular Molars in Dentate and Edentulous Sites Using Cone Beam Computed Tomography: A Cross-Sectional Study.","authors":"Zahra Safari,&nbsp;Mitra Ghazizadeh Ahsaie,&nbsp;Yaser Safi","doi":"10.1615/JLongTermEffMedImplants.2022039842","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022039842","url":null,"abstract":"<p><p>Determining the position of the Inferior alveolar nerve (IAN) is an important factor prior to any surgical procedure in the mandible such as dental implant insertion and surgical tooth extraction. The aim of this study was to compare the position of IAN in partially edentulous patients in the lower first and second molars in both missing and dentate sides. A total of 200 CBCT scans were chosen randomly and examined. On cross-sectional views, the distance between lower border of IAN canal and upper border of inferior cortex of mandible (IC) were measured at the site of dentate and edentulous mandibular first and second molar. Paired-sample t-test was used to analyze and compare measurements on right and left sides. A total of 100 males and 100 females with mean age of 46.05 ± 12.33 years were included. The IC distance measured in four pairs were as follows: Pair one: 80 cases with right missing 6 (mean ± SD = 3.73 ± 1.29 mm) and left present 6 (mean ± SD = 3.42 ± 1.20 mm), Pair two: 20 cases with right present 6 (mean = 3.20 ± 1.48 mm) and left missing 6 (mean ± SD = 3.96 ± 1.62 mm), Pair three: 54 cases of right missing 7 (mean ± SD = 3.83 ± 1.74 mm) and left present 7 (mean ± SD = 3.62 ± 1.74 mm), and Pair four: 46 case of right present 7 (mean ± SD = 3.49 ± 1.56 mm) and left missing 7 (mean ± SD = 3.84 ± 1.42). The IAN was statistically more distant from inferior cortex of mandible in the edentulous parts compared with the non-edentulous part (P < 0.05). The IAN was positioned farther from the inferior cortex of mandible in edentulous sites compared with dentate parts. Cautious consideration is essential in any surgical procedure and dental implant operations to prevent IAN injury.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 3","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40417042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelioid Hemangioma of Bone: A Rare Vascular Neoplasm. A Case Report and Literature Review.","authors":"Olga Savvidou,&nbsp;Penelope Korkolopoulou,&nbsp;Eleftheria Lakiotaki,&nbsp;Spyros Sioutis,&nbsp;Christos Vottis,&nbsp;Panagiotis Gavriil,&nbsp;Dimitra Melissaridou,&nbsp;Panayiotis Papagelopoulos","doi":"10.1615/JLongTermEffMedImplants.2022041868","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022041868","url":null,"abstract":"<p><p>Epithelioid hemangioma (EH) of bone is a rare benign, albeit locally aggressive vascular neoplasm. It is usually solitary and involves the metaphysis or diaphysis of long tubular bones, especially in the lower extremities. Rarely it may present as multifocal lesions. The differential diagnosis includes malignant vascular bone tumors such as epithelioid hemangioendothelioma and epithelioid angiosarcoma. Clinical presentation and radiographic and histological findings are not specific and diagnosis is based mostly on immunohistochemical and molecular studies. There is no consensus regarding the optimal treatment. Curettage and bone grafting or en bloc resection are the current treatment options, however local recurrence have been reported. We present a case of multifocal EH of the distal tibia, distal fibula and hindfoot in a 38 year-old male managed with curettage, radiofrequency ablation and cement osteoplasty. The imaging features, histological findings and treatment options of this rare vascular tumor are discussed.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 4","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33439160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Removal of Bone Bridge and Interposition of the Extensor Digitorum Brevis in the Treatment of Calcaneonavicular Coalition in Pediatric Patients: A Case Series, Short Review, and Commentary.","authors":"Stavros Angelis,&nbsp;Dimitrios Myrgiotis,&nbsp;Alexandros P Apostolopoulos,&nbsp;Eleftherios Mandragos,&nbsp;Nikolaos-Christos Statyris,&nbsp;Dimitrios K Filippou,&nbsp;John Ν Michelarakis","doi":"10.1615/JLongTermEffMedImplants.2022042255","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2022042255","url":null,"abstract":"<p><p>This study retrospectively presents a single-clinic case series of pediatric patients with calcaneonavicular coalition treated by surgical removal of the bone bridge and interposition of the extensor digitorum brevis. This technique is currently the most cited and utilized protocol in operative treatment. Clinical, functional, and radiological results are analyzed and compared with related research. This is a single-clinic retrospective study, conducted for a period of 15 years. One independent investigator reviewed medical records and conducted a de-identified preoperative, inpatient, and postoperative assessment focused on demographic data, history and clinical evaluation, imaging assessment, American Orthopedic Foot and Ankle Society (AOFAS) scoring, and complication analysis. Of 34 patients, 13 met the inclusion criteria. Mean patient age was 11.2 years; 10 were males and 3 were females. Pathology concerned the right lower limb in eight cases and the left in five. Mean time between diagnosis and surgical intervention was 4.3 months and mean postoperative follow-up was 27.2 months. Thorough overview of reported symptoms, identified signs, imaging evaluation, functional outcomes, and adverse effects was performed. Bone bridge removal and interposition of the extensor digitorum brevis is an effective method of treating the condition. Despite drawbacks, results are comparable or even, to some degree, superior to other techniques.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"32 4","pages":"27-37"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33439158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}