Journal of Hepato‐Biliary‐Pancreatic Sciences最新文献

{"title":"Letter to the Editor: Clinical and Radiological Predictive Features for High-Grade and Invasive Carcinoma in Intraductal Papillary Mucinous Neoplasms","authors":"Uday Singh Dadhwal","doi":"10.1002/jhbp.70134","DOIUrl":"10.1002/jhbp.70134","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"33 9","pages":"e79-e80"},"PeriodicalIF":2.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Survey of Technical Preferences for Robotic Versus Laparoscopic Segmentectomy of Liver Segments 7 and 8: A 2024 PAM-HBP Surgery Project","authors":"Keiichi Akahoshi,&nbsp;Taiga Wakabayashi,&nbsp;Hitoe Nishino,&nbsp;Atsushi Oba,&nbsp;Paolo Magistri,&nbsp;Kenichiro Araki,&nbsp;Kwangpyo Hong,&nbsp;Ruben Ciria,&nbsp;Iswanto Sucandy,&nbsp;Catherine Teh,&nbsp;Fabrizio Di Benedetto,&nbsp;Ayako Yamazaki,&nbsp;Daisuke Ban,&nbsp;Shintaro Kuroda,&nbsp;Yasuko Matsuo,&nbsp;Sohei Satoi,&nbsp;Taizo Hibi,&nbsp;Etsuro Hatano,&nbsp;Go Wakabayashi,&nbsp;Ken Shirabe,&nbsp;Itaru Endo,&nbsp;Yuichi Nagakawa,&nbsp;Masayuki Ohtsuka","doi":"10.1002/jhbp.70125","DOIUrl":"10.1002/jhbp.70125","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Segmentectomy of liver segments 7 and 8 (S7/8) is technically challenging due to their posterosuperior location and proximity to major hepatic veins. With the increasing adoption of robotic surgery, current practices for S7/8 resection across different surgical modalities remain unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An international web-based survey was conducted in 2024 among expert hepatobiliary surgeons. The 18-item questionnaire addressed institutional policies, technical preferences, and procedural strategies for laparoscopic and robotic S7/8 segmentectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 67 surgeons from 11 countries responded. Among them, 51% had performed over 20 laparoscopic S7/8 resections, whereas 57% had no experience with the robotic approach. Robotic S7/8 segmentectomy accounted for fewer than 20% of cases at most institutions. The Glissonean approach from the hilum and the Maryland bipolar dissector were more frequently used in robotic procedures. The cranio-dorsal approach to the right hepatic vein was less common in robotic surgery, while the cranio-ventral approach to the middle hepatic vein was common to both modalities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Robotic S7/8 segmentectomy remains in the early stages of adoption despite ergonomic and technical advantages. This international survey highlights distinct technical differences between laparoscopic and robotic approaches, emphasizing the need for targeted training and standardized device integration.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"33 9","pages":"680-689"},"PeriodicalIF":2.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jhbp.70125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147982141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Development and Validation of Nomogram Predicting Survival in Resectable Gallbladder Cancer.","authors":"Shraddha Patkar, Tanvi M Shah, Mahesh Goel","doi":"10.1002/jhbp.70189","DOIUrl":"https://doi.org/10.1002/jhbp.70189","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149016853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-Guided Hepaticogastrostomy Using a Novel Ultra-Tapered Bougie Dilator for Effective Bile Aspiration During Tract Dilation.","authors":"Shuntaro Mukai, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Kazumasa Nagai, Hiroyuki Kojima, Hirohito Minami, Noriyuki Hirakawa, Takao Itoi","doi":"10.1002/jhbp.70185","DOIUrl":"https://doi.org/10.1002/jhbp.70185","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hidden Architecture of Pancreatic Ducts: 3D Anatomical Reconstruction and Its Implication on Pancreatic Resection.","authors":"Sébastien Frey, Luisa Nogueira, Sébastien Gaujoux, Karim Manai, Lilian Pimont, Karl Baqué, Michel Rayar, Nicolas Bronsard, Alain Sauvanet, Patrick Baqué","doi":"10.1002/jhbp.70191","DOIUrl":"https://doi.org/10.1002/jhbp.70191","url":null,"abstract":"<p><strong>Background/purpose: </strong>Postoperative pancreatic fistula (POPF) is a common complication after pancreatic surgery and its mechanisms remain incompletely understood. While the diameter of the main pancreatic duct is well-known to be a risk factor of POPF, the impact of branch duct's (BD) anatomy is not known.</p><p><strong>Methods: </strong>All consecutive pancreas procured from body donations were prospectively studied between March 2024 and March 2025. After total pancreatectomy, the main pancreatic and accessory ducts, when present, were cannulated and injected with polymerizable resin. Tissue corrosion using potassium hydroxide produced detailed 3D casts. BD were analyzed according to number, order, and angulation.</p><p><strong>Results: </strong>Thirty 3D casts were analyzed from donors. The median number of BD was 96 ± 27, including 45 ± 8 first-order BD. Pancreatic heads exhibited the highest number of BD, while the isthmus showed the fewest (p < 0.001). Mean angulation increased progressively from 74° ± 14° in the isthmus to 81° ± 12° in the tail (p = 0.351). Ductal bifurcation of the main pancreatic duct at the corporeocaudal junction was present in 17%. The cephalic and uncinate regions displayed the most complex networks and included long ascending and descending branches.</p><p><strong>Conclusions: </strong>Pancreatic ductal network shows substantial regional variability, which may partly explain differences in POPF risk according to the transection site.</p>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective Evaluation of Serum MUC5AC for Predicting Malignancy in Patients With Acute Cholangitis.","authors":"Merve Aslan, Muhammed Fatih Acehan, Fatma Meriç Yılmaz, İhsan Ateş","doi":"10.1002/jhbp.70187","DOIUrl":"https://doi.org/10.1002/jhbp.70187","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the diagnostic performance of serum MUC5AC for predicting malignancy in acute cholangitis patients, comparing it with CA19-9 and bilirubin.</p><p><strong>Methods: </strong>This prospective study included 163 patients hospitalized with acute cholangitis. Serum MUC5AC was measured by ELISA within 24 h of admission. Clinical, laboratory, imaging, and pathological findings were reviewed to categorize patients into benign or malignant groups.</p><p><strong>Results: </strong>Multivariate analysis identified MUC5AC and total bilirubin as independent predictors of malignant cholangitis. Higher MUC5AC (OR: 1.2385, 95% CI: 1.0906-1.4065, p = 0.0006) and elevated total bilirubin (OR: 1.2086, 95% CI: 1.1068-1.3197, p < 0.001) were independently associated with malignancy. CA19-9 was significantly associated with malignant cholangitis in univariate analysis but lost significance in multivariate analysis. Among malignant cases, median MUC5AC levels were significantly higher in metastatic than resectable patients, suggesting an association between elevated MUC5AC and advanced disease stage.</p><p><strong>Conclusion: </strong>MUC5AC is a promising biomarker for predicting malignant etiology in acute cholangitis, offering additional diagnostic value alongside established markers like CA19-9 and total bilirubin.</p>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Surgery for Pancreatic Cancer: Oncological Principles Must Come First.","authors":"Wataru Kimura","doi":"10.1002/jhbp.70188","DOIUrl":"https://doi.org/10.1002/jhbp.70188","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148969392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter regarding 'Histological analysis of cryopreserved venous allografts used for liver transplantation and hepato-biliary-pancreatic surgery'.","authors":"Kiyoshi Hasegawa, Yusuke Seki","doi":"10.1002/jhbp.70176","DOIUrl":"https://doi.org/10.1002/jhbp.70176","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148969406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Histological Analysis of Cryopreserved Venous Allografts Used for Liver Transplantation and Hepato-Biliary-Pancreatic Surgery\".","authors":"Bisma Nadeem, Qurat Ul Ain, Labiqa Khowaja","doi":"10.1002/jhbp.70184","DOIUrl":"https://doi.org/10.1002/jhbp.70184","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel High-Quality Fluoroscopic Image Processing System With More Than 50% Radiation Dose Reduction in Endoscopic Retrograde Cholangiopancreatography (With Video).","authors":"Mitsuru Okuno, Kensaku Yoshida, Tsuyoshi Mukai, Fumiya Kataoka, Mizuki Ohashi, Hiroki Jinno, Ryotaro Nagao, Naoki Mita, Hisataka Moriwaki, Masahito Shimizu","doi":"10.1002/jhbp.70183","DOIUrl":"https://doi.org/10.1002/jhbp.70183","url":null,"abstract":"<p><strong>Objectives: </strong>Radiation dose reduction is an important consideration in ERCP. However, the low radiation dose compromises image quality. This study evaluated the utility of radiation-reduction settings in a fluoroscopic system.</p><p><strong>Methods: </strong>Three fluoroscopic settings (high-dose, low-dose, and low-dose with a new image processor; SCORE PRO Advance [SPA]) were compared.</p><p><strong>Results: </strong>From 2024 to 2025, high-dose (124-patients), low-dose (110-patients), and SPA (135-patients) were evaluated. There were no significant differences in baseline characteristics of patients and the details of the ERCP procedure, except for sex distribution. High-dose (skin dose [SD]:72.6 [mGy]/dose area product [DAP]:233.9 [dGy・cm²]) showed a significantly higher radiation dose than low-dose (40.0/121.9) and SPA (32.5/109.4) (p < 0.01). For ERCP, procedure time was significantly longer in low-dose than in SPA (22 vs. 17 min; p = 0.04). In multivariate analysis, high-dose (SD: odds ratio [OR] 31.6, p < 0.01/DAP:OR17.7, p < 0.01) and long ERCP procedure time (OR3.33, p < 0.01/OR3.90, p < 0.01) were related to the high radiation dose exposure. SPA was independently associated with shorter ERCP procedure time (OR 0.63; p = 0.04).</p><p><strong>Conclusions: </strong>SPA and low-dose provided comparable reductions in radiation exposure. Furthermore, SPA was associated with a shorter ERCP time than a low dose, possibly because of improved image quality. However, until fluoroscopic systems are upgraded to incorporate SPA, low-dose may provide clinical utility for reducing radiation exposure.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: UMIN000061448.</p>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}