Journal of Hepato‐Biliary‐Pancreatic Sciences最新文献

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Predicting early rebleeding and mortality after endoscopic hemostasis of esophagogastric varices: Diagnostic performance of aspartate aminotransferase-to-platelet ratio index and model for end-stage liver disease-Na score 预测食管胃静脉曲张内镜止血后的早期再出血和死亡率:天冬氨酸氨基转移酶与血小板比率指数和终末期肝病-Na评分模型的诊断性能。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-18 DOI: 10.1002/jhbp.12057
Shinya Yokoyama, Takashi Honda, Yoji Ishizu, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Kazuyuki Mizuno, Masanao Nakamura, Hiroki Kawashima
{"title":"Predicting early rebleeding and mortality after endoscopic hemostasis of esophagogastric varices: Diagnostic performance of aspartate aminotransferase-to-platelet ratio index and model for end-stage liver disease-Na score","authors":"Shinya Yokoyama,&nbsp;Takashi Honda,&nbsp;Yoji Ishizu,&nbsp;Norihiro Imai,&nbsp;Takanori Ito,&nbsp;Kenta Yamamoto,&nbsp;Kazuyuki Mizuno,&nbsp;Masanao Nakamura,&nbsp;Hiroki Kawashima","doi":"10.1002/jhbp.12057","DOIUrl":"10.1002/jhbp.12057","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Endoscopic variceal ligation and sclerotherapy are recommended for esophagogastric variceal bleeding (EGVB) in cirrhosis but can be complicated by early rebleeding and death. This study aimed to identify noninvasive markers accurately predicting early rebleeding and mortality after endoscopic hemostasis for EGVB.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Among 116 patients with endoscopically confirmed EGVB and endoscopic hemostasis, various noninvasive markers were calculated, and their predictive accuracy was compared by receiver-operating characteristic curve analysis. Endpoints included 5-day rebleeding, 5-day mortality, 6-week rebleeding, and 6-week mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The median age was 63 years. Child-Pugh class B and C patients accounted for 40.5% and 34.5%, respectively. Only the aspartate aminotransferase-to-platelet ratio index (APRI) significantly predicted 5-day rebleeding, with an area under the curve (AUC) of 0.777 (95% confidence interval [CI]: 0.537–1). The model for end-stage liver disease-Na (MELD-Na) score showed good predictive accuracy for 5-day mortality (AUC: 0.839, 95% CI: 0.681–0.997), 6-week rebleeding (AUC: 0.797, 95% CI: 0.663–0.932), and 6-week mortality (AUC: 0.888, 95% CI: 0.797–0.979).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Patients with cirrhosis with a high APRI and MELD-Na score were at high risk of early rebleeding and death after EGVB. Allocating appropriate monitoring and care for those patients is necessary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 11","pages":"830-839"},"PeriodicalIF":3.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicenter study comparing EUS-guided hepaticogastrostomy and ERCP for malignant biliary obstruction in patients with accessible papillae 比较 EUS 引导下肝胃切除术和 ERCP 治疗可触及乳头的恶性胆道梗阻患者的多中心研究。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-18 DOI: 10.1002/jhbp.12055
Takeshi Ogura, Hirotoshi Ishiwatari, Susumu Hijioka, Kotaro Takeshita, Junya Sato, Mamoru Takenaka, Tomohiro Fukunaga, Shunsuke Omoto, Nao Fujimori, Akihisa Ohno, Keiichi Hatamaru, Takaaki Tamura, Hajime Imai, Masanori Yamada, Akitoshi Hakoda, Hiroki Nishikawa, Masayuki Kitano
{"title":"Multicenter study comparing EUS-guided hepaticogastrostomy and ERCP for malignant biliary obstruction in patients with accessible papillae","authors":"Takeshi Ogura,&nbsp;Hirotoshi Ishiwatari,&nbsp;Susumu Hijioka,&nbsp;Kotaro Takeshita,&nbsp;Junya Sato,&nbsp;Mamoru Takenaka,&nbsp;Tomohiro Fukunaga,&nbsp;Shunsuke Omoto,&nbsp;Nao Fujimori,&nbsp;Akihisa Ohno,&nbsp;Keiichi Hatamaru,&nbsp;Takaaki Tamura,&nbsp;Hajime Imai,&nbsp;Masanori Yamada,&nbsp;Akitoshi Hakoda,&nbsp;Hiroki Nishikawa,&nbsp;Masayuki Kitano","doi":"10.1002/jhbp.12055","DOIUrl":"10.1002/jhbp.12055","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>One advantage of endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is that it is difficult for reflux cholangitis, caused by duodenal pressure increasing due to duodenal obstruction, to occur. In addition, since stent deployment is performed away from the malignant stricture site, longer stent patency than with endoscopic retrograde cholangiopancreatography (ERCP) may be obtained. However, no study has previously compared EUS-HGS and ERCP for patients without duodenal obstruction or surgically altered anatomy. The aim of the present study was to compare clinical outcomes between EUS-HGS and ERCP in normal anatomy patients without duodenal obstruction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>In the ERCP group, patients who initially underwent biliary drainage were included. In the EUS-HGS group, patients who underwent EUS-HGS due to failed biliary cannulation were included. Patients with an inaccessible papilla, such as with surgically altered anatomy or duodenal obstruction, were excluded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 314 patients who underwent ERCP and EUS-HGS were enrolled in this study. Of the 314 patients, 289 underwent biliary stenting under ERCP guidance, and 25 patients underwent biliary stenting under EUS-HGS. After propensity score-matching analysis, the adverse event rate tended to be lower in the EUS-HGS group than in the ERCP group. Although overall survival was not significantly different between the EUS-HGS and ERCP groups (<i>p</i> = .228), stent patency was significantly longer in the EUS-HGS group (median 366.0 days) than in the ERCP group (median 76.5 days).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>EUS-HGS had a lower adverse event rate, shorter procedure time, and longer stent patency than ERCP in cases of normal anatomy without duodenal obstruction.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 9","pages":"680-687"},"PeriodicalIF":3.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of an innovative basket catheter for endoscopic removal of fragmented or small pancreatic stones 创新型篮式导管在内窥镜下取出碎小胰腺结石的实用性。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-17 DOI: 10.1002/jhbp.12041
Akihisa Kato, Michihiro Yoshida, Hiromi Kataoka
{"title":"Utility of an innovative basket catheter for endoscopic removal of fragmented or small pancreatic stones","authors":"Akihisa Kato,&nbsp;Michihiro Yoshida,&nbsp;Hiromi Kataoka","doi":"10.1002/jhbp.12041","DOIUrl":"10.1002/jhbp.12041","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 10","pages":"e56-e57"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging role of local treatment in the era of advanced systemic treatment in pancreatic cancer with liver metastasis: A systematic review and meta-analysis 肝转移胰腺癌晚期全身治疗时代局部治疗的新作用:系统综述和荟萃分析。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-17 DOI: 10.1002/jhbp.12051
Won-Gun Yun, Youngmin Han, Hye-Sol Jung, Wooil Kwon, Joon Seong Park, Jin-Young Jang
{"title":"Emerging role of local treatment in the era of advanced systemic treatment in pancreatic cancer with liver metastasis: A systematic review and meta-analysis","authors":"Won-Gun Yun,&nbsp;Youngmin Han,&nbsp;Hye-Sol Jung,&nbsp;Wooil Kwon,&nbsp;Joon Seong Park,&nbsp;Jin-Young Jang","doi":"10.1002/jhbp.12051","DOIUrl":"10.1002/jhbp.12051","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Approximately 50% of pancreatic cancer cases are diagnosed with distant metastases, commonly in the liver, leading to poor prognosis. With modern chemotherapy regimens extending patient survival and stabilizing metastasis, there has been a rise in the use of local treatments. However, the effectiveness for local treatment remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>PubMed, Embase, and Cochrane databases were searched for studies reporting the survival outcomes of pancreatic cancer cases with isolated synchronous or metachronous liver metastases who underwent curative-intent local treatment. Hazard ratios were combined using a random-effects model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The full texts of 102 studies were screened, and 14 retrospective studies were included in the meta-analysis. Among patients with synchronous liver metastases, overall survival was significantly better in those who underwent curative-intent local treatment than in those who did not (hazard ratio [HR]: 0.35, 95% confidence interval [CI]: 0.24–0.52). Among patients with metachronous liver metastases, overall survival was also significantly better in those who underwent curative-intent local treatment than in those who did not (HR 0.37, 95% CI: 0.19–0.73).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Curative-intent local treatment may be a feasible option for highly selected pancreatic cancer cases with liver metastases. However, the optimal strategy for local treatments should be explored in future studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 9","pages":"601-610"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of intraoperative surgical difficulty during laparoscopic cholecystectomy using drip infusion cholangiography with computed tomography 使用计算机断层扫描滴注胆管造影术预测腹腔镜胆囊切除术的术中手术难度。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-17 DOI: 10.1002/jhbp.12044
Atsuro Fujinaga, Teijiro Hirashita, Yuichi Endo, Hiroki Orimoto, Shota Amano, Masahiro Kawamura, Takahide Kawasaki, Takashi Masuda, Masafumi Inomata
{"title":"Prediction of intraoperative surgical difficulty during laparoscopic cholecystectomy using drip infusion cholangiography with computed tomography","authors":"Atsuro Fujinaga,&nbsp;Teijiro Hirashita,&nbsp;Yuichi Endo,&nbsp;Hiroki Orimoto,&nbsp;Shota Amano,&nbsp;Masahiro Kawamura,&nbsp;Takahide Kawasaki,&nbsp;Takashi Masuda,&nbsp;Masafumi Inomata","doi":"10.1002/jhbp.12044","DOIUrl":"10.1002/jhbp.12044","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Although findings from drip infusion cholangiography with computed tomography (DIC-CT) are useful in preoperative anatomic evaluation for laparoscopic cholecystectomy (LC), their relationship with intraoperative surgical difficulty based on the difficulty score (DS) proposed by Tokyo Guidelines 2018 is unclear. We examined this relationship.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were collected from 202 patients who underwent LC for benign gallbladder (GB) disease with preoperative DIC-CT in our department. DIC-CT findings were classified into GB-positive and GB-negative groups based on GB opacification, and clinical characteristics were compared. DS assessed only on findings from around Calot's triangle was considered “cDS”, and patients were divided into cDS ≤2 and ≥3 groups. Preoperative data including DIC-CT findings were evaluated using multivariate analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>DIC-CT findings showed 151 (74.8%) GB-positive and 51 (25.2%) GB-negative patients. Surgical outcomes were significantly better in the GB-positive versus GB-negative group for operation time (107 vs. 154 min, <i>p</i> &lt; .001), blood loss (8 vs. 25 mL, <i>p</i> &lt; .001), cDS (0.8 vs. 2.2, <i>p</i> &lt; .001), and critical view of safety score (4.0 vs. 3.1, <i>p</i> &lt; .001). cDS was ≤2 in 174 (86.1%) and ≥3 in 28 (13.9%) patients. By multivariate analysis, DIC-CT findings and alkaline phosphatase values were independent factors predicting intraoperative difficulty.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>DIC-CT findings are useful for predicting cDS in LC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 9","pages":"637-646"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Troubleshooting bile leakage after endoscopic ultrasound-guided hepaticogastrostomy with fully covered self-expandable metal stent deployment 在内窥镜超声引导下进行肝胃造口术并植入全覆盖自膨胀金属支架后的胆汁渗漏故障诊断。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-17 DOI: 10.1002/jhbp.12052
Naosuke Kuraoka, Tetsuro Ujihara, Shun Sakai
{"title":"Troubleshooting bile leakage after endoscopic ultrasound-guided hepaticogastrostomy with fully covered self-expandable metal stent deployment","authors":"Naosuke Kuraoka,&nbsp;Tetsuro Ujihara,&nbsp;Shun Sakai","doi":"10.1002/jhbp.12052","DOIUrl":"10.1002/jhbp.12052","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 9","pages":"e51-e52"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypocalcemia and acute pancreatitis: New perspectives 低钙血症与急性胰腺炎:新视角。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-16 DOI: 10.1002/jhbp.12059
Osman Cagin Buldukoglu
{"title":"Hypocalcemia and acute pancreatitis: New perspectives","authors":"Osman Cagin Buldukoglu","doi":"10.1002/jhbp.12059","DOIUrl":"10.1002/jhbp.12059","url":null,"abstract":"","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 10","pages":"e60"},"PeriodicalIF":3.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of aging on peribiliary glands in ischemia–reperfusion injury 缺血再灌注损伤中衰老对胆囊周围腺体的影响
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-16 DOI: 10.1002/jhbp.12047
Kaoru Katano, Shinichi Nakanuma, Tomokazu Tokoro, Ryohei Takei, Satoshi Takada, Mitsuyoshi Okazaki, Kaichiro Kato, Isamu Makino, Kenichi Harada, Shintaro Yagi
{"title":"Impact of aging on peribiliary glands in ischemia–reperfusion injury","authors":"Kaoru Katano,&nbsp;Shinichi Nakanuma,&nbsp;Tomokazu Tokoro,&nbsp;Ryohei Takei,&nbsp;Satoshi Takada,&nbsp;Mitsuyoshi Okazaki,&nbsp;Kaichiro Kato,&nbsp;Isamu Makino,&nbsp;Kenichi Harada,&nbsp;Shintaro Yagi","doi":"10.1002/jhbp.12047","DOIUrl":"10.1002/jhbp.12047","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The detailed mechanisms underlying the development of ischemia-type biliary lesions (ITBLs) in aged donor grafts remain unclear. In the present study we aimed to investigate the impact of aging on the response of the peribiliary gland (PBG) to ischemia–reperfusion injury (IRI) and its temporal changes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Experiments were performed using a 90-min partial warm liver ischemia model in male Wistar rats of two age groups: young (7–8 weeks old) and old (52–60 weeks old). Liver tissues were obtained 24, 72, and 168 h after IRI. Histopathological and immunohistochemical assessments of the perihilar bile duct (PHBD), including the PBG, distal to the clip-clamped site were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Young rats showed little change in the bile duct tissues after IRI. However, old rats showed an increased PBG volume in the PHBD and marked PBG cell proliferation 24 h after IRI. Bile duct wall thickening with narrowing of the lumen peaked 72 h after IRI. Mucus production and oxidative stress in the PBG were significantly higher in old than in young rats after IRI. These findings showed a trend toward improvement 168 h after IRI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Age-dependent differences in the response of the PBG to IRI may be related to differences in ITBL frequency.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 10","pages":"705-715"},"PeriodicalIF":3.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141620171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re-evaluation of risk and oncological outcomes of resection of veins and arteries in the resection of pancreatic cancer 重新评估胰腺癌切除术中切除静脉和动脉的风险和肿瘤效果。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-07-14 DOI: 10.1002/jhbp.12048
Mirang Lee, Yoon Soo Chae, Seulah Park, Won-Gun Yun, Hye-Sol Jung, Youngmin Han, Wooil Kwon, Joon Seong Park, Jin-Young Jang
{"title":"Re-evaluation of risk and oncological outcomes of resection of veins and arteries in the resection of pancreatic cancer","authors":"Mirang Lee,&nbsp;Yoon Soo Chae,&nbsp;Seulah Park,&nbsp;Won-Gun Yun,&nbsp;Hye-Sol Jung,&nbsp;Youngmin Han,&nbsp;Wooil Kwon,&nbsp;Joon Seong Park,&nbsp;Jin-Young Jang","doi":"10.1002/jhbp.12048","DOIUrl":"10.1002/jhbp.12048","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Advances in chemotherapy have led to increasing major vascular resection during pancreatectomy which has been contraindicated due to high morbidity. This study aimed to verify the safety and oncological outcomes of vascular resection during pancreatectomy in the era of neoadjuvant therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from patients who underwent surgery for pancreatic cancer at Seoul National University Hospital between 2001 and 2021 were reviewed. Clinicopathological outcomes were analyzed according vessel resection. A propensity-score-matched (PSM) analysis was performed to evaluate survival outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 1596 patients, the proportion of those who underwent vascular resection increased from 9.2% to 23.4% over time divided into 5-year intervals. There were no differences in major complications (15.6% vs. 13.0%; <i>p</i> = .266) and 30-day mortality rate (0.3% vs. 0.6%; <i>p</i> = .837) between the vascular and nonvascular resection groups. After PSM, the vascular resection group demonstrated comparable survival outcome with the nonvascular resection group (5 year-survival-rate 20.4 vs. 23.7%; <i>p</i> = .194). Arterial resection yielded comparable survival outcome with nonvascular resection (5 year-survival-rate 38.1% vs. 23.7%; <i>p</i> = .138).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Appropriate vascular resection―even arterial―is safe and effective in patients carefully selected for radical surgery in the era of neoadjuvant therapy. Further studies are needed to determine the optimal indication and method for vascular resection in patients with pancreatic cancer.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":"31 9","pages":"671-679"},"PeriodicalIF":3.2,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subdivision of pT1N0 (American Joint Committee on Cancer 8th edition) distal cholangiocarcinoma for adjuvant chemotherapy consideration 对 pT1N0(美国癌症联合委员会第 8 版)远端胆管癌进行细分,以考虑辅助化疗。
IF 3.2 3区 医学
Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2024-06-30 DOI: 10.1002/jhbp.12010
Shimpei Otsuka, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Yoshiyasu Kato, Kageyama Yumiko, Nobuyuki Ohike, Takashi Sugino, Katsuhiko Uesaka
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