Journal of Hypertension最新文献

{"title":"Diagnostic performance of simplified ambulatory nocturnal blood pressure monitoring for nocturnal hypertension and target organ damage assessment.","authors":"Qing Liu, Yukun Liang, Yancui Sun, Minghui Gong, Minghui Yang, Ying Zhang, Yinong Jiang, Wei Song","doi":"10.1097/HJH.0000000000004378","DOIUrl":"10.1097/HJH.0000000000004378","url":null,"abstract":"<p><strong>Objective: </strong>Nocturnal blood pressure (BP) is a more sensitive predictor of cardiovascular risk. However, frequent nighttime measurements may disrupt sleep and reduce patient compliance. Therefore, this study aimed to investigate whether simplified nocturnal or awake BP readings could effectively diagnose nocturnal hypertension (NHT) and assess associated target organ damage (TOD).</p><p><strong>Methods: </strong>Two thousand four hundred seventy-five hypertensive patients with complete 24-h ambulatory BP monitoring (ABPM) data between January 2021 and December 2023 were recruited in this retrospective study. Six SBP indicators, including fixed-interval SBP, extended-interval SBP, evening SBP, morning SBP, daytime SBP, and morning-evening average SBP, were adopted to explore the agreement with mean nocturnal SBP and diagnostic potential for NHT, as well as their relationship with TOD.</p><p><strong>Results: </strong>Among different SBPs, fixed-interval SBP (measured at 02 : 00, 03 : 00, and 04 : 00) showed the strongest correlation with nocturnal SBP ( r  = 0.961, P  < 0.001). Bland-Altman analysis indicated good agreement, with a mean bias of 0.81 mmHg (95% confidence interval: 0.61-1.01) and 95.1% of data points falling within the limits of agreement, further supported by an intraclass correlation coefficient of 0.960. Compared to other five SBPs, fixed-interval SBP demonstrated the best diagnostic performance for NHT (area under the curve = 0.974, P  < 0.001) with the optimal cut-off 120.5 mmHg. Logistic analysis confirmed that fixed-interval SBP remained independently associated with TOD risk after multivariable adjustment.</p><p><strong>Conclusion: </strong>Our analysis suggests that a simplified 3-time-point nocturnal SBP protocol might be considered as a potential alternative to conventional ABPM for diagnosing NHT and evaluating TOD.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":"1617-1625"},"PeriodicalIF":5.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can placental histology reveal preexisting hypertension in patients who develop preeclampsia?","authors":"Lydia Hadj Youcef, Clemence Jacquin, Pauline Orquevaux, Philippe Rieu, Rene Gabriel, Olivier Graesslin, Benjamin Birene, Vincent Dupont","doi":"10.1097/HJH.0000000000004373","DOIUrl":"10.1097/HJH.0000000000004373","url":null,"abstract":"<p><strong>Background: </strong>Hypertension can be both a cause and a consequence of preeclampsia, complicating diagnosis and postpartum management. Placental histopathology has been proposed as a tool to distinguish preeclampsia superimposed on chronic hypertension from de-novo disease, yet specific and reliable markers remain poorly defined.</p><p><strong>Objective: </strong>To evaluate the association between placental histological features and preexisting hypertension in a cohort of patients who developed preeclampsia.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of 321 preeclamptic pregnancies at a tertiary center between January 1, 2020, and October 31, 2023. Preexisting hypertension was defined as the use of antihypertensive medication at the beginning of pregnancy. Placental histopathological evaluation was available for 223 patients. Histological lesions were classified according to established guidelines, with a focus on maternal vascular malperfusion features. Associations between placental lesions and preexisting hypertension were assessed using univariate and multivariate analyses.</p><p><strong>Results: </strong>The absence of placental infarction (47.4 vs. 61.1%, P  = 0.02) and the presence of decidual arteriopathy (31.6 vs. 16.8%, P  = 0.03) were significantly associated with preexisting hypertension. The combination of these two features was independently associated with preexisting hypertension (odds ratio = 5.90; 95% confidence interval 1.88-18.60; P  < 0.01). This pattern demonstrated high specificity (96.2%) but low sensitivity (18.4%) for identifying preexisting hypertension.</p><p><strong>Conclusion: </strong>The presence of decidual arteriopathy in the absence of placental infarction is strongly associated with preexisting hypertension in preeclamptic patients. Although its low sensitivity limits its use as a screening tool, its high specificity suggests that it may serve as a useful indicator of underlying chronic hypertension when present. These findings support the potential role of placental histopathology as an adjunct to clinical evaluation in the postpartum assessment of hypertensive disorders.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":"1579-1584"},"PeriodicalIF":5.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13566486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of obstructive sleep apnea-hypopnea syndrome on coronary microcirculation in hypertensive patients.","authors":"Peipei Feng, Bo Wang, Xuekui Liu, Nan Lv, Tingting Zhou, Yueyue Feng, Ming Lou","doi":"10.1097/HJH.0000000000004370","DOIUrl":"10.1097/HJH.0000000000004370","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) on coronary microcirculatory function in hypertensive patients and explore potential mechanisms.</p><p><strong>Methods: </strong>A total of 87 patients underwent cardiac stress echocardiography, and 376 patients underwent angiography-derived microvascular resistance (AMR) assessment based on quantitative flow ratio (QFR) technology. All patients completed portable sleep monitoring. Based on the monitoring results and hypertension history, patients were categorized into five groups: control, hypertension alone, OSAHS alone, hypertension with mild OSAHS, and hypertension with moderate-to-severe OSAHS. Parameters including sleep monitoring data, coronary flow velocity reserve (CFVR), AMR, high-sensitivity C-reactive protein (hs-CRP), and interleukin-6 (IL-6) were compared among groups. Multivariable logistic regression analysis was performed to assess the influence of different groupings on coronary microvascular dysfunction.</p><p><strong>Results: </strong>The Hypertension with moderate-to-severe OSAHS group demonstrated significantly lower CFVR ( P  < 0.05) and significantly higher left anterior descending artery AMR (LAD-AMR), hs-CRP, and IL-6 levels compared to all other groups ( P  < 0.05). Multivariable logistic regression analysis revealed that, compared to the control group, hypertension with moderate-to-severe OSAHS was an independent correlate of both reduced CFVR [odds ratio (OR) = 6.06, 95% confidence interval (CI): 2.87-12.78] and elevated LAD-AMR (OR = 5.60, 95% CI: 4.10-7.10).</p><p><strong>Conclusion: </strong>In hypertensive patients, co-existing moderate-to-severe OSAHS is associated with more severe coronary microvascular dysfunction and elevated levels of inflammatory markers.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":"1547-1555"},"PeriodicalIF":5.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13566393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic recognition of primary aldosteronism in clinical practice.","authors":"Arindam Bagga, Ramzi Ibrahim, Rahmeh Alasmar, Hoang Nhat Pham, Ipsa Arora, Shady Abohashem, David Simper, Steven J Lester, Chadi Ayoub, Reza Arsanjani","doi":"10.1097/HJH.0000000000004430","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004430","url":null,"abstract":"<p><p>Primary aldosteronism is an underdiagnosed and potentially treatable cause of secondary hypertension. We evaluated the incidence of clinically recognized primary aldosteronism among adults with clinically coded hypertension receiving intensive multidrug antihypertensive therapy in the TriNetX Analytics Network from 2010 through 2024. Among 1 888 042 eligible adults without prior primary aldosteronism, 1528 incident diagnoses were identified, corresponding to an incidence proportion of 0.081%, or 0.81 cases per 1000 patients. Diagnostic recognition varied by demographic subgroup and was highest among younger adults, males, Black or African American individuals, and Hispanic or Latino individuals. These findings suggest that documented recognition of primary aldosteronism in routine clinical practice remains low even among patients receiving intensive antihypertensive therapy. Because diagnoses were identified using electronic health record coding rather than systematic biochemical testing, results should be interpreted as clinical recognition rather than true disease prevalence.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of long-term all-cause mortality and incident disability in older hypertensive outpatients.","authors":"Giulia Rivasi, Chiara Salucci, Giuseppe D'Ambrosio, Virginia Gori, Marco Capacci, Greta Ceccarelli, Michele Vinci, Vincenzo Giosuè Giambusso, Alessandra Liccardo, Maria Francesca Bisignano, Lorenza Rossi, Giulia Spanalatte, Eleonora Rizzi, Enrico Mossello, Andrea Ungar","doi":"10.1097/HJH.0000000000004431","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004431","url":null,"abstract":"<p><strong>Objective: </strong>In previous studies involving older hypertensive adults, geriatric conditions with potential prognostic impact and outcomes of geriatric relevance (e.g., disability) remained largely unexplored. This study investigated predictors of all-cause mortality and incident disability in a real-world sample of older hypertensive outpatients undergoing comprehensive geriatric assessment.</p><p><strong>Methods: </strong>We analyzed data from the longitudinal HYPER-FRAIL pilot study, involving hypertensive outpatients ≥75 years undergoing comprehensive geriatric assessment, office, ambulatory and home blood pressure (BP) measurements. Predictors of long-term all-cause mortality and incident disability in basic activities of daily living (BADL) were assessed using multivariate Cox and logistic regression analyses, respectively.</p><p><strong>Results: </strong>Among 112 participants (mean age 81.2 years, 58% women, median follow-up 55 months), mortality was 25.9%. Baseline BADL disability, impaired physical performance and frailty independently predicted mortality. Stratified analyses showed that higher BP was associated with increased mortality risk only in patients with preserved autonomy in instrumental activities of daily living (IADL). Among those with IADL disability, office diastolic BP <80 mmHg and ambulatory 24 h systolic BP <130 mmHg were associated with increased mortality. Among 78 participants with baseline BADL autonomy, disability incidence was 39.7%. Predictors included baseline IADL and physical impairment, cognitive decline and ambulatory daytime hypotension. The association with hypotension was independent of falls or syncope, but not of dementia.</p><p><strong>Conclusions: </strong>Disability, impaired physical performance and frailty predicted all-cause mortality in older hypertensive outpatients. The association between BP and mortality varied by functional status, suggesting a modifying - possibly reversing - effect. Ambulatory hypotension was associated with incident disability.</p><p><strong>Graphical abstract: </strong>https://links.lww.com/HJH/D93.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skeletal muscle index modulates the reduction of aortic pressure augmentation after foam rolling.","authors":"Kaname Tagawa, Hibiki Kawatani, Jun Sugawara, Youngju Choi, Seiji Maeda","doi":"10.1097/HJH.0000000000004424","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004424","url":null,"abstract":"<p><strong>Objective: </strong>Foam rolling reduces vascular resistance and enhances peripheral blood flow; however, its ability to attenuate pressure wave reflection remains purely hypothetical. Given the positive correlation between skeletal muscle mass and flow-mediated vasodilation, the present study investigated the acute effects of foam rolling on pressure wave reflection and explored whether skeletal muscle index moderates this response.</p><p><strong>Methods: </strong>Twenty-six men and women (age, 22-62 years) completed 20 min of foam rolling and sham control on separate days in a randomized controlled crossover design. Skeletal muscle index was calculated as skeletal muscle mass/height2 (bioelectrical impedance analysis), and the BMI as body weight/height2. Carotid pressure waveforms were recorded to derive time to reflection, reflection magnitude, and aortic augmentation index at baseline, and at 10 and 30 min postintervention.</p><p><strong>Results: </strong>Foam rolling elicited reductions in aortic augmentation index at 10 min (P < 0.001) and 30 min (P = 0.021) postintervention. Reflection magnitude decreased 10 min after foam rolling (P < 0.001), whereas the time to reflection remained unchanged. Skeletal muscle index correlated negatively with reductions in augmentation index (r = -0.45, P = 0.021) and reflection magnitude (r = -0.41, P = 0.049) at 10 min, even after adjusting for age, sex, and BMI (both P < 0.05).</p><p><strong>Conclusion: </strong>Foam rolling acutely attenuated aortic pressure augmentation by reducing the magnitude rather than the timing of peripheral wave reflections. Moreover, individuals with greater muscle mass may derive more substantial cardiovascular benefits from foam rolling.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure monitoring via wearable devices and artificial intelligence in hypertension detection.","authors":"Luca Neri, Alessandro Orro, Nazareno Paolocci, Claudio Borghi, Merat Bagha","doi":"10.1097/HJH.0000000000004419","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004419","url":null,"abstract":"<p><strong>Graphical abstract: </strong>https://links.lww.com/HJH/D83.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure and homocysteine-lowering effects of the amlodipine/folic acid combination in patients with hypertension and serum homocysteine concentration ≥10 μmol/l (H-type hypertension): a multicenter, randomized, double-blind, parallel-controlled clinical trial.","authors":"Jianping Li, Yan Zhang, Fangfang Fan, Tieci Yi, Xiaoshu Cheng, Huihui Bao, Xiao Huang, Yundai Chen, Hao Xue, Fang Chen, Changyan Wu, Zhihong Han, Wenli Cheng, Pingjin Gao, Jin Zhang, Changsheng Sheng, Ye Tian, Hong Guo, Zhirong Wang, Chen Yao, Xianhui Qin, Genfu Tang, Binyan Wang, Yimin Cui, Jiguang Wang, Fan Fan Hou, Yong Huo","doi":"10.1097/HJH.0000000000004420","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004420","url":null,"abstract":"<p><strong>Background: </strong>Elevated plasma homocysteine (Hcy ≥10 μmol/l) and hypertension, defined as H-type hypertension, can synergistically increase the risk of cardiovascular diseases, especially for stroke. We aimed to assess the efficacy and safety of amlodipine-folic acid in lowering both blood pressure (BP) and plasma Hcy, compared with amlodipine alone.</p><p><strong>Methods: </strong>Eligible participants (299 males and 241 females) were randomly assigned in a 1:1:1 ratio to 5 mg amlodipine (control, group A), 5 mg amlodipine plus 0.4 mg folic acid (group B), or 5 mg amlodipine plus 0.8 mg folic acid (group C). All participants were followed at 2, 4, 6, and 8 weeks. The primary outcome was the efficacy of lowering both BP and Hcy.</p><p><strong>Results: </strong>Among the 540 participants who were randomized, the efficacy of lowering both BP and Hcy was significantly better in groups B and C compared with group A at the end of 4 weeks, and sustained at the end of 8 weeks (group B vs. group A: 31.7% vs. 6.1%, P < 0.001; group C vs. group A: 32.8% vs. 6.1%, P < 0.001). Both groups B and C were more efficacious in lowering Hcy and raising folate levels than amlodipine alone at 8 weeks. There was no significant difference in BP lowering and adverse events among the three treatment groups.</p><p><strong>Conclusions: </strong>In H-type hypertension patients, amlodipine-folic acid (5 mg/0.4 mg or 5 mg/0.8 mg) had a significantly higher efficacy of lowering both BP and plasma Hcy compared with amlodipine alone. The efficacy of BP lowering and safety profile were comparable among the three treatment groups. This trial was registered in clinicaltrials.gov, identifier: NCT01848873.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marinobufagenin and left ventricular mass and geometry in patients with essential hypertension.","authors":"Cristina Politi, Marco Mobrici, Alessandra Testa, Patrizia Pizzini, Rocco Tripepi, Rosa Maria Parlongo, Giovanni Tripepi, Davide Bolignano, Belinda Spoto","doi":"10.1097/HJH.0000000000004437","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004437","url":null,"abstract":"<p><strong>Aims: </strong>Marinobufagenin (MBG), the endogenous cardiotonic inhibitor of the transmembrane adenosine triphosphatase sodium-potassium pump, is a steroid hormone with divergent effects on blood pressure and cardiovascular (CV) system. In response to sodium load, MBG stimulates natriuresis to compensate for body fluid overload but, in condition of sustained high sodium intake, its excessive production promotes a maladaptive pro-hypertensive effect. Since the role of MBG on the cardiac alterations frequently affecting hypertensive patients has been poorly investigated, we focused on gaining insight into this relationship in essential hypertension.</p><p><strong>Methods: </strong>We studied the relationships between MBG, LV mass and geometry and investigated whether diuretic therapy modifies these associations in 180 incident-prevalent patients with essential hypertension.</p><p><strong>Results: </strong>Serum MBG levels were significantly lower in hypertensive patients than in normotensive individuals (P = 0.005) and strongly associated with the mass and muscle component of the left ventricle. On multivariable linear regression models, left ventricular mass index and the cardiac measurements posterior wall thickness, interventricular septal thickness, mean wall thickness, relative wall thickness increased in parallel with the decrease in serum MBG levels (P ≤ 0.01). Coherently, in a multivariable logistic model, the odds of having cardiac remodeling/hypertrophy increased by 9% for each 0.1 nmol/l MBG reduction (odds ratio: 1.09, 95% confidence interval: 1.01-1.18, P = 0.03). Furthermore, diuretic therapy modified the link between MBG and cardiac biomarkers by acting as an amplifier of the harmful effect of low MBG levels on these measures.</p><p><strong>Conclusions: </strong>In patients with essential hypertension, lower circulating levels of MBG are associated with alterations in myocardial morphology whose severity is modified by the diuretic therapy that amplifies the noxious effect of low MBG levels.</p><p><strong>Graphical abstract: </strong>https://links.lww.com/HJH/D96.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertensive disorders of pregnancy and the risk for hypertension and cardiovascular and kidney disease. International Society of Hypertension position paper, endorsed by the World Hypertension League and European Society of Hypertension.","authors":"Erika S W Jones, Udaya Ralapanawa, Pensee Wu, Lizzy M Brewster, Anne Monique Nuyt, Kaylee Slater, Mariane Bertagnolli, Muscha Steckelings, Thenral Socrates, Laura A Magee, Yan Li, Tazeen H Jafar, George Stergiou","doi":"10.1097/HJH.0000000000004389","DOIUrl":"https://doi.org/10.1097/HJH.0000000000004389","url":null,"abstract":"<p><p>Hypertensive disorders of pregnancy (HDP) remain a leading cause of maternal and perinatal morbidity and mortality worldwide, especially in low- and middle-income countries. Moreover, HDP are directly linked to an increased risk of long-term cardiometabolic and kidney disease in mothers and offspring. Since prevention, diagnosis, and treatment of HDP remain suboptimal globally, enhanced understanding and implementation of current guidelines on HDP present a substantial opportunity to significantly reduce maternal and fetal morbidity and mortality. This position paper by the International Society of Hypertension reviews current knowledge in the field, identifies knowledge gaps and provides recommendations on the care of women with HDP and lifelong care, thereafter.</p>","PeriodicalId":16043,"journal":{"name":"Journal of Hypertension","volume":" ","pages":""},"PeriodicalIF":5.6,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}