Journal of Glaucoma最新文献

{"title":"Incidence and Factors Associated With Postoperative Intraocular Pressure Spike Following Micropulse Transscleral Laser Therapy.","authors":"Sunee Chansangpetch, Thitiwat Puttiteerachot, Kitiya Ratanawongphibul, Rath Itthipanichpong, Anita Manassakorn, Visanee Tantisevi, Prin Rojanapongpun, Shan C Lin","doi":"10.1097/IJG.0000000000002677","DOIUrl":"10.1097/IJG.0000000000002677","url":null,"abstract":"<p><strong>Précis: </strong>We investigated early IOP changes after MPTLT in glaucoma patients. Sixteen percent experienced transient IOP spikes at 1 hour. Alpha-2 adrenergic agonist use was associated with reduced IOP elevation and lower spike risk.</p><p><strong>Purpose: </strong>To assess the incidence and contributing factors of postoperative intraocular pressure (IOP) spike following micropulse transscleral laser therapy (MPTLT).</p><p><strong>Patients and methods: </strong>This prospective observational study included 80 eyes from 66 glaucoma participants undergoing MPTLT. An IOP spike was defined as an increase of 5 mm Hg or more at 1 hour postlaser compared with baseline. Demographic and clinical factors were assessed, and multivariable backward stepwise regression mixed-effect models were used to identify significant associations. The main outcome measures were the change in IOP at 1 hour (1 h IOP minus baseline IOP) and the occurrence of a 1-hour IOP spike.</p><p><strong>Results: </strong>The mean (SD) IOP change was -0.16 (6.40) mm Hg at 1 hour. Thirteen eyes (16%) met the criteria for the IOP spike, with the average change of 9.73 (5.57) mm Hg. Among these, 5 eyes (6% of all eyes) had an IOP rise of >10 mm Hg. All eyes with an IOP spike had an IOP return to baseline levels or lower at 18 hours. Pre-existing use of alpha-2 adrenergic (AA) agonists (coefficient -4.31, 95% CI: -7.61 to -1.01, P =0.01) and higher baseline IOP (coefficient -0.12, 95% CI: -0.23 to -0.004, P =0.042) were associated with less IOP elevation. Pre-existing use of AA agonists was identified as a protective factor for developing an IOP spike with an odds ratio of 0.20 (95% CI: 0.42 to 0.91, P =0.038).</p><p><strong>Conclusions: </strong>One sixth of the patients experienced a postoperative IOP spike. Participants with pre-existing use of AA agonists tended to have a lower degree of IOP change and a lower IOP spike.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"179-184"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145768234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Intraocular Pressure Elevation in Steep Trendelenburg Position During Surgery.","authors":"Irem Durmus, Merve Bulun Yediyildiz, Hulya Ak Yilmaz, Kubra Taskin, Erdi Karadağ, Emre Mat, Banu Çevik","doi":"10.1097/IJG.0000000000002683","DOIUrl":"10.1097/IJG.0000000000002683","url":null,"abstract":"<p><strong>Précis: </strong>The STP significantly increases IOP during TLH, with a more pronounced effect observed in patients with a high BMI.</p><p><strong>Purpose: </strong>The present study sought to determine the impact of steep Trendelenburg position (STP) on intraocular pressure (IOP) in patients undergoing total laparoscopic hysterectomy (TLH) and to establish the relationship between age, body mass index (BMI), iridocorneal angle, and surgical duration about position-related intraocular pressure changes.</p><p><strong>Methods: </strong>Preoperative ophthalmologic evaluation was performed 1 day before surgery (T0). IOP was measured using a handheld contact tonometer at T1 (5 min after anesthesia), T2 (5 min after pneumoperitoneum), T3 (5 min in STP), T4 (after pneumoperitoneum release), T5 (at the end of surgery in supine position), and T6 (10 min after returning to supine). Surgery duration and patient demographics were recorded.</p><p><strong>Results: </strong>The IOP values were found to be considerably elevated in comparison to the baseline (T0) at all designated time points (T1-T6). There was a progressive decrease in intra-abdominal pressure after the pneumoperitoneum was released (T4-T6). The findings revealed no statistically significant correlation between age and iridocorneal angle on the one hand and IOP values on the other. At T6, a negative correlation was observed between IOP and surgical duration and a positive correlation with BMI.</p><p><strong>Conclusions: </strong>The STP significantly elevates IOP during TLH, and this effect is more pronounced in patients with higher BMI. Identifying such risk factors may guide anesthetic and surgical strategies to minimize ocular complications in procedures requiring this position.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"185-189"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Glaucoma Treatment Information on Social Media Using Large Language Models.","authors":"Asha Bulusu, Paul R Cotran, Amer M Alwreikat, Ying Jiang, Michael Lee Cooper, Kathryn Moynihan Ramsey, Ashwin P Verghese, David J Ramsey","doi":"10.1097/IJG.0000000000002673","DOIUrl":"10.1097/IJG.0000000000002673","url":null,"abstract":"<p><strong>Précis: </strong>This study investigates the accuracy, readability, utility, and educational value of glaucoma treatment content on social media platforms and explores how large language models assess the quality of social media posts compared with glaucoma experts.</p><p><strong>Purpose: </strong>To assess the quality of information on glaucoma treatment available on social media platforms.</p><p><strong>Methods: </strong>A 30-question survey consisting of the \"top posts\" from three social media platforms (X, Instagram, and Reddit) was assessed by 5 board-certified glaucoma experts across four domains (readability, utility, educational value, and accuracy) by using a 5-point Likert scale. The overall quality of each post was calculated as the average of the median score assigned to each of the four domains to create a reference standard. Expert agreement was assessed using Kendall's coefficient of concordance ( W ). A large language model (LLM), GPT-4 (OpenAI), was then prompted to evaluate the same posts with identical instructions. Agreement with expert consensus was compared using Cohen weighted kappa ( κ ), and the difference in favorability of each post assessed using McNemar exact test.</p><p><strong>Results: </strong>Fewer than half of social media posts on glaucoma treatment were judged favorably by glaucoma experts (40%). GPT-4 was less critical of social media content and provided a favorable rating nearly twice as often (77%, P =0.017). Despite this difference, there was moderate agreement between the LLM compared with the glaucoma experts ( κ =0.421, P =0.005). The lack of agreement predominantly stemmed from cases where the experts rated the content unfavorably, with disagreement occurring in 56% of cases, compared with 0% when the content was deemed favorable ( P =0.005).</p><p><strong>Conclusions: </strong>Although glaucoma experts and artificial intelligence (AI)-based systems were in moderate agreement when evaluating the quality of posts, the LLM was less able to discriminate posts of low quality.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"173-178"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Glaucoma Progression After Acute Primary Angle Closure.","authors":"Ping Huang, Wesam S Shalaby, Yining Guo, Rongrui Liu, Chengkai Zhou, Xinzuo Zhou, Jiaxing Xie, Chun Zhang, Jonathan Myers","doi":"10.1097/IJG.0000000000002670","DOIUrl":"10.1097/IJG.0000000000002670","url":null,"abstract":"<p><strong>Précis: </strong>In acute primary angle closure, early cataract extraction is protective against glaucomatous progression through better IOP control, while higher mean IOP and worse baseline visual field defects are associated with increased risk.</p><p><strong>Purpose: </strong>To evaluate long-term outcomes and identify risk factors for glaucomatous optic neuropathy (GON) progression after acute primary angle closure (APAC).</p><p><strong>Methods: </strong>In this multicenter retrospective cohort study, we enrolled 156 eyes from 130 APAC patients with ≥2 years of follow-up. Baseline clinical features, including visual field mean deviation (VFMD) and optical coherence tomography (OCT) parameters, as well as follow-up intraocular pressure (IOP) and interventions, were collected. GON progression was defined by concordant structural and functional changes. Univariate and multivariate logistic regression were used to identify risk factors.</p><p><strong>Results: </strong>The mean age was 63.9±9.6 years, and 71.5% of patients were female. During follow-up, 129 eyes (82.7%) underwent cataract extraction and 49 eyes (31.4%) underwent glaucoma surgery. Visual acuity, IOP, and medication burden improved (all P <0.05), whereas mean VFMD and OCT retinal nerve fiber layer (RNFL) thickness did not show a significant change. Twenty-three eyes (14.7%) were blind; 15 (9.6%) due to glaucoma alone. In multivariable analysis, higher mean follow-up IOP (aOR: 1.14 per mm Hg, P =0.005) and worse baseline VFMD (aOR: 1.07 per 1 dB worsening, P =0.048) independently predicted progression, while early cataract extraction (<3 mo) was protective (aOR: 0.43, P =0.047), an effect partly mediated through IOP reduction (indirect effect β=-0.20, 95% CI: -0.39 to -0.04).</p><p><strong>Conclusions: </strong>After APAC, higher mean IOP and worse baseline VFMD are associated with GON progression. Early cataract extraction may reduce progression risk, partly through improved IOP control.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"166-172"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Diagnostic Capacity and Correlation of Optic Nerve Colorimetry With Structural Parameters in Primary Open Angle Glaucoma.","authors":"Manuel Gonzalez de la Rosa","doi":"10.1097/IJG.0000000000002653","DOIUrl":"https://doi.org/10.1097/IJG.0000000000002653","url":null,"abstract":"","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":"35 3","pages":"e13"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glaucoma Diagnosis in Randomized Trials: Variability and the Need for Standardization.","authors":"Iden Amiri, Vincent Tang, Jean-Claude Mwanza, Gabriella Szatmary, David Fleischman","doi":"10.1097/IJG.0000000000002684","DOIUrl":"10.1097/IJG.0000000000002684","url":null,"abstract":"<p><strong>Purpose: </strong>Glaucoma, a leading cause of irreversible blindness, lacks a universally accepted diagnostic definition, resulting in significant variability across clinical trials. This systematic review evaluates and categorizes the diagnostic criteria employed for glaucoma in randomized controlled trials (RCTs) over the past decade.</p><p><strong>Methods: </strong>A systematic review of PubMed and ClinicalTrials.gov databases was performed for RCTs published between January 1, 2014, and December 31, 2024, involving adults diagnosed with primary open-angle glaucoma or normal-tension glaucoma. Studies explicitly stating diagnostic criteria were included. Extracted diagnostic criteria were categorized into clinically relevant groups.</p><p><strong>Results: </strong>Of 482 identified articles, 83 met inclusion criteria. Significant variability in glaucoma definitions was observed, encompassing 57 unique definitions. Criteria differed notably in intraocular pressure (45 unique definitions), visual field impairment (40), structural optic nerve parameters (35), and retinal nerve fiber layer assessments (15). Definitions were grouped into Mixed Criteria (37.3%), Combined Comprehensive (31.3%), IOP-Emphasized (27.7%), Visual Field-Emphasized (2.4%), and Imaging-Focused (1.2%).</p><p><strong>Conclusions: </strong>Substantial heterogeneity exists in glaucoma diagnostic criteria across recent RCTs, complicating clinical comparability and risking diagnostic inaccuracies. This highlights the urgent need for universally standardized definitions informed by collaborative international consensus, incorporating structural-functional correlations and advanced imaging technologies.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"e7-e12"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"24-Hour Intraocular Pressure Rhythms and Measurement Frequency in Glaucoma Using an Intraocular Telemetry Sensor.","authors":"Julien Torbey, Robert N Weinreb, Harsha L Rao, Kaweh Mansouri","doi":"10.1097/IJG.0000000000002671","DOIUrl":"10.1097/IJG.0000000000002671","url":null,"abstract":"<p><strong>Précis: </strong>An implantable IOP sensor study in glaucoma patients found that 5 evenly spaced daily measurements over 18 waking hours effectively reflect the 24-hour IOP rhythm, with peaks and troughs often occurring outside clinic hours.</p><p><strong>Purpose: </strong>The availability of an implantable IOP sensor enables patients to obtain IOP measurements over 24 hours and on demand. The current study assesses the optimal frequency of daily IOP measurements required to reflect the 24-hour IOP rhythm in glaucoma patients.</p><p><strong>Methods: </strong>Twenty-two patients with primary open angle glaucoma (POAG) who had previously been implanted with a sulcus-based IOP sensor (Eyemate-IO, Implandata, Germany) as part of the prospective multicentric ARGOS-02 study were enrolled. The following parameters were used to characterize the 24-hour IOP rhythm: distribution of IOP measurements and timing of IOP peaks and troughs. To assess the optimal number of IOP values to predict the 24-hour rhythm, the daily count of IOP measurements and the time interval between the first and last daily measurements were used. The correlation with the detection of daily IOP variability was assessed through Student t test and a kernel-density estimate using Gaussian kernels and Earth Movers Distance.</p><p><strong>Results: </strong>Twenty-two patients (8 female and 14 male) with a mean age of 67.8±6.8 years were followed up over 6.6±1.7 years with a total of 80,495 IOP measurements. The percentage of peak IOP values was highest (50.6%) during the early morning hours (4-5 am), while trough measurements occurred predominantly (42.3%) during the late-night hours (between 11 pm and 12 pm). Five IOP measurements equally distributed over an 18-hour period were sufficient to characterize the 24-hour rhythm. Additional measurements did not yield any statistically significant value in the characterization of 24-hour IOP patterns.</p><p><strong>Conclusions: </strong>Using an implanted telemetric sensor, the results of this study show that 5 daily IOP measurements evenly spread over 18 hours, provide sufficient information for assessment of the diurnal IOP rhythm. However, patients in practice recorded on average 4 measurements over 14 hours, highlighting the gap between the ideal recommendation and real-life adherence.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":"143-149"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145762585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Endothelium Cell Loss after Ahmed and Baerveldt Glaucoma Drainage Device Implantation: A Systematic Review and Meta-analysis.","authors":"Anna Dastiridou, Maria-Eleni Pappa, Konstantinos Benekos, Sofia Androudi, Ioannis Tsinopoulos, Andreas Katsanos","doi":"10.1097/IJG.0000000000002707","DOIUrl":"10.1097/IJG.0000000000002707","url":null,"abstract":"<p><strong>Précis: </strong>GDD implantation in the anterior chamber is associated with progressive corneal endothelial cell loss over time, with evidence suggesting a more pronounced effect in Asian compared to Caucasian eyes.</p><p><strong>Purpose: </strong>Corneal endothelial cell damage occurs with various surgical procedures. This systematic review and meta-analysis aims to investigate the impact of Ahmed or Baerveldt glaucoma drainage device (GDD) implantation on corneal endothelial cell density (ECD).</p><p><strong>Methods: </strong>Database search involved MEDLINE, EMBASE, Scopus, NIH Clinical Trials (http://www.clinicaltrials.gov/), and Google Scholar (PROSPERO ID:CRD42024521140). The included studies focused on standalone GDD implantation in eyes without pre-existing corneal endothelial pathologies and with a minimum follow-up of 12 months. The quality of the studies was assessed using the Cochrane Risk of Bias Tool (ROBINS-I).</p><p><strong>Results: </strong>Fourteen studies were included in the quantitative synthesis, comprising 572 eyes. ECD after anterior chamber GDD implantation decreased by 204.7 cells/mm2 (95%CI:149.2,260.1, I2=61.04%) at 12 months. Subgroup analysis revealed a greater ECD loss in predominantly Asian (MD,225.5cells/mm2; 95% CI:151.1,300.0, I2=67.4%) compared to predominantly Caucasian population (MD,155.3cells/mm2; 95%CI:94.5,216.2, I2=0%) and no difference between Ahmed and Baerveldt GDD. Sensitivity analysis showed ECD loss of 227.1 cells/mm2 (95%CI:182.6,271.6, I2=32.6%). At 24 months after anterior chamber GDD implantation, ECD decreased by 287.8 cells/mm2 (95%CI: 233.0, 342.7, I2=53.4%). ECD loss at 12 months after sulcus or pars plana placement varied between 12-629.6cells/mm2, but significant heterogeneity in studies precluded meta-analysis of available data.</p><p><strong>Conclusion: </strong>Overall, implantation of a GDD leads to clinically relevant corneal endothelial cell loss. ECD loss may be more pronounced in Asians compared to Caucasians. No difference in ECD loss was observed between the two GDD types GDD. The existing evidence is characterized by heterogeneity, and further high-quality randomized controlled trials are necessary to establish definitive estimates.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of 360-Degree Trabeculotomy versus Traditional Angle Surgery in Primary Congenital Glaucoma: A Systematic Review and Meta-Analysis.","authors":"Johar Abbas, Faseeh Haider, Hajira Arooj, Zainab Rustam, Saumya Srivastava, Haseeb Haider, Vatsal Makhija, Saloni Srivastava, Fatima Binte Athar, Faizan Ahmed, Zahra Arsalan, Bo Wang","doi":"10.1097/IJG.0000000000002705","DOIUrl":"10.1097/IJG.0000000000002705","url":null,"abstract":"<p><strong>Précis: </strong>Systematic meta-analysis demonstrates greater IOP reduction, fewer glaucoma medication use and higher surgical success rate with 360-degree trabeculotomy compared to traditional angle surgery in primary congenital glaucoma.</p><p><strong>Purpose: </strong>Primary congenital glaucoma (PCG) is a rare vision threatening disorder, which can lead to blindness if untreated. The aim of the study is to compare the effectiveness of traditional angle surgery (goniotomy and rigid probe trabeculotomy) versus 360° trabeculotomy in children with PCG.</p><p><strong>Methods: </strong>A comprehensive search was conducted across PubMed, EMBASE, Scopus, Cochrane (CENTRAL), Science Direct and Clinicaltrials.gov. A total of 1740 studies were obtained from databases, and 12 studies, 3 RCTs and 9 Retrospective studies met the inclusion criteria. Mean Differences (MD) for continuous outcomes and Odds Ratios (OR) for dichotomous outcomes were analyzed. The primary outcomes were the reduction in intraocular pressure (IOP) and numbers of anti-glaucoma medications at 12 months postoperatively.</p><p><strong>Results: </strong>Pooled analysis of 778 eyes demonstrated that 360° trabeculotomy showed significant reduction in IOP and number of anti-glaucoma medications compared to traditional angle surgery by -2.10 mmHg (-3.26,-0.94; P=0.0004, I²=55%) and -0.47 drops (-0.69, -0.25; P<0.0001, I²=55%), respectively. Compared to traditional angle surgery group, the 360° trabeculotomy group showed higher complete and qualified success rates with OR of 5.07 (3.43-7.50; P<0.0001, I²=4%) and 3.00 (1.47-6.12; P=0.003, I²=46%) respectively, and as well as, reduction in failure rate with OR of 0.18 (0.11-0.31; P<0.0001, I²=14%). No statistically significant differences were observed for post-operative axial length, change in cup/disc ratio, change in horizontal corneal diameter.</p><p><strong>Conclusions: </strong>360° trabeculotomy showed greater reduction in IOP and number of anti-glaucoma medications postoperatively than traditional angle surgery with improved success and reduced failure rates.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147510993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Risk Factors for Ciliochoroidal Detachment Following Preserflo MicroShunt Implantation.","authors":"Taro Baba, Naoki Okada, Kana Tokumo, Hirokazu Sakaguchi, Kazuyuki Hirooka","doi":"10.1097/IJG.0000000000002708","DOIUrl":"10.1097/IJG.0000000000002708","url":null,"abstract":"<p><strong>Précis: </strong>Short axial length and postoperative hypotony are significantly associated with ciliochoroidal detachment following Preserflo MicroShunt implantation.</p><p><strong>Purpose: </strong>This study investigated the incidence and associated factors of ciliochoroidal detachment (CCD) following Preserflo MicroShunt (PFM) implantation.</p><p><strong>Materials and methods: </strong>PFM implantation, with or without combined cataract surgery, was performed on 83 eyes from August 2023 to June 2024. CCD was evaluated using anterior segment optical coherence tomography on postoperative day 1, and at 1 week, and 1 month, 2 months, and 3 months. Multiple logistic regression was used to identify associated factors with the developing of CCD.</p><p><strong>Results: </strong>CCD occurred in 56 of 83 eyes (67.5%). CCD was observed in 48 eyes (57.8%) on day 1, 53 eyes (63.9%) at 1 week, 18 eyes (21.7%) at 1 month, 4 eyes (4.8%) at 2 months, and 1 eye (1.2%) at 3 months. Intraocular pressure (IOP) (mmHg) was significantly lower in eyes with CCD than in those without CCD at all time points except at 2 months: 5.9±2.9 vs. 8.3±5.0 (P=0.008) on day 1; 6.8±3.2 vs. 9.9±7.0 (P=0.02) at 1 week; 7.9±4.4 vs. 11.6±5.7 (P=0.001) at 1 month; 7.0±4.1 vs. 11.4±4.8 (P=0.055) at 2 months; and 2.0 vs. 11.6±4.0 (P=0.045) at 3 months. The short axial length (P=0.005) and postoperative hypotony (IOP ≤6 mmHg) (P=0.03) were significantly associated with CCD.</p><p><strong>Conclusion: </strong>CCD is common after PFM implantation. Short axial length and postoperative hypotony are significant risk factors.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}