Zinn-Haller 毛细血管周围动脉环与高度近视眼青光眼的关系

IF 2 4区 医学 Q2 OPHTHALMOLOGY
Ji Hong Kim, Jooyoung Yoon, Kyeong Ik Na, Rim Kyung Hong, Won June Lee
{"title":"Zinn-Haller 毛细血管周围动脉环与高度近视眼青光眼的关系","authors":"Ji Hong Kim, Jooyoung Yoon, Kyeong Ik Na, Rim Kyung Hong, Won June Lee","doi":"10.1097/IJG.0000000000002514","DOIUrl":null,"url":null,"abstract":"<p><strong>Prcis: </strong>The visualization of circle of Zinn-Haller (CZH) on optical coherence tomography angiography (OCTA) or its pattern does not have a clear effect on glaucoma, while the location of CZH is associated with axial length in highly myopic eyes.</p><p><strong>Purpose: </strong>To investigate the association between the CZH and the presence of glaucoma using swept-source optical coherence tomography angiography (SS-OCTA) images of the optic nerve of patients with high myopia (HM).</p><p><strong>Methods: </strong>This retrospective case series included 227 eyes with HM, comprising 134 and 93 eyes with and without glaucoma, respectively. The characteristics of CZH, including visualization, pattern, and location, were assessed using SS-OCTA. Vascular parameters, such as vessel density and microvascular dropout (MvD), were quantified. The factors affecting the presence of glaucoma and the correlations between the CZH distance and axial length (AXL) were identified using logistic regression analysis and Pearson correlation analysis, respectively.</p><p><strong>Results: </strong>CZH was detected more frequently in HM patients with glaucoma (71.6%) than in patients without glaucoma (51.6%) (P<0.002). However, the visualization of CZH was not related to the presence of glaucoma in multivariate regression analysis (odds ratio [OR], 0.688; 95% confidence interval [CI], 0.328-1.444; P=0.322). Moreover, compared to the annular pattern used as a reference, triangular and irregular patterns were not associated with the presence of glaucoma (OR: 1.043, 95% CI: 0.101-10.763, P=0.971; OR: 0.527, 95% CI: 0.255-1.092, P=0.085, respectively). MvD was significantly higher in patients with glaucoma (61.2%) than that in patients without glaucoma (2.2%) (P<0.001) and was identified as a significant factor affecting the presence of glaucoma (OR, 42.120; 95% CI, 9.416-188.413; P<0.001). AXL showed a significant correlation with CZH distance in all patients (R=0.399; P<0.001).</p><p><strong>Conclusions: </strong>CZH was more commonly detected in HM patients with glaucoma. However, no clear associations of glaucoma with the visualization, pattern, or location of CZH were observed in the present study. The correlation between AXL and CZH distance in eyes with HM warrants further investigation. These results may offer insights into the pathogenesis of glaucoma in eyes with HM as OCTA technology advances.</p>","PeriodicalId":15938,"journal":{"name":"Journal of Glaucoma","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association of Peripapillary Arterial Circle of Zinn-Haller with Glaucoma in Highly Myopic Eyes.\",\"authors\":\"Ji Hong Kim, Jooyoung Yoon, Kyeong Ik Na, Rim Kyung Hong, Won June Lee\",\"doi\":\"10.1097/IJG.0000000000002514\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Prcis: </strong>The visualization of circle of Zinn-Haller (CZH) on optical coherence tomography angiography (OCTA) or its pattern does not have a clear effect on glaucoma, while the location of CZH is associated with axial length in highly myopic eyes.</p><p><strong>Purpose: </strong>To investigate the association between the CZH and the presence of glaucoma using swept-source optical coherence tomography angiography (SS-OCTA) images of the optic nerve of patients with high myopia (HM).</p><p><strong>Methods: </strong>This retrospective case series included 227 eyes with HM, comprising 134 and 93 eyes with and without glaucoma, respectively. The characteristics of CZH, including visualization, pattern, and location, were assessed using SS-OCTA. Vascular parameters, such as vessel density and microvascular dropout (MvD), were quantified. The factors affecting the presence of glaucoma and the correlations between the CZH distance and axial length (AXL) were identified using logistic regression analysis and Pearson correlation analysis, respectively.</p><p><strong>Results: </strong>CZH was detected more frequently in HM patients with glaucoma (71.6%) than in patients without glaucoma (51.6%) (P<0.002). However, the visualization of CZH was not related to the presence of glaucoma in multivariate regression analysis (odds ratio [OR], 0.688; 95% confidence interval [CI], 0.328-1.444; P=0.322). Moreover, compared to the annular pattern used as a reference, triangular and irregular patterns were not associated with the presence of glaucoma (OR: 1.043, 95% CI: 0.101-10.763, P=0.971; OR: 0.527, 95% CI: 0.255-1.092, P=0.085, respectively). MvD was significantly higher in patients with glaucoma (61.2%) than that in patients without glaucoma (2.2%) (P<0.001) and was identified as a significant factor affecting the presence of glaucoma (OR, 42.120; 95% CI, 9.416-188.413; P<0.001). AXL showed a significant correlation with CZH distance in all patients (R=0.399; P<0.001).</p><p><strong>Conclusions: </strong>CZH was more commonly detected in HM patients with glaucoma. However, no clear associations of glaucoma with the visualization, pattern, or location of CZH were observed in the present study. The correlation between AXL and CZH distance in eyes with HM warrants further investigation. These results may offer insights into the pathogenesis of glaucoma in eyes with HM as OCTA technology advances.</p>\",\"PeriodicalId\":15938,\"journal\":{\"name\":\"Journal of Glaucoma\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-10-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Glaucoma\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/IJG.0000000000002514\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Glaucoma","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/IJG.0000000000002514","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

Prcis:目的:使用高度近视(HM)患者视神经的扫源光学相干断层血管成像(SS-OCTA)图像,研究CZH与青光眼之间的关联:该回顾性病例系列包括 227 例 HM 患者,其中有青光眼和无青光眼的患者分别为 134 例和 93 例。使用 SS-OCTA 评估了 CZH 的特征,包括可视化、模式和位置。对血管密度和微血管脱落(MvD)等血管参数进行了量化。利用逻辑回归分析和皮尔逊相关分析,分别确定了影响青光眼存在的因素以及 CZH 距离与轴长(AXL)之间的相关性:有青光眼的 HM 患者(71.6%)比无青光眼的患者(51.6%)更常检测到 CZH(PC 结论:有青光眼的 HM 患者更常检测到 CZH,无青光眼的 HM 患者更常检测到 CZH:在患有青光眼的HM患者中更常检测到CZH。然而,本研究并未观察到青光眼与 CZH 的可视化、模式或位置有明显关联。HM患者眼中AXL和CZH距离之间的相关性值得进一步研究。随着 OCTA 技术的发展,这些结果可能会为 HM 患者青光眼的发病机制提供启示。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of Peripapillary Arterial Circle of Zinn-Haller with Glaucoma in Highly Myopic Eyes.

Prcis: The visualization of circle of Zinn-Haller (CZH) on optical coherence tomography angiography (OCTA) or its pattern does not have a clear effect on glaucoma, while the location of CZH is associated with axial length in highly myopic eyes.

Purpose: To investigate the association between the CZH and the presence of glaucoma using swept-source optical coherence tomography angiography (SS-OCTA) images of the optic nerve of patients with high myopia (HM).

Methods: This retrospective case series included 227 eyes with HM, comprising 134 and 93 eyes with and without glaucoma, respectively. The characteristics of CZH, including visualization, pattern, and location, were assessed using SS-OCTA. Vascular parameters, such as vessel density and microvascular dropout (MvD), were quantified. The factors affecting the presence of glaucoma and the correlations between the CZH distance and axial length (AXL) were identified using logistic regression analysis and Pearson correlation analysis, respectively.

Results: CZH was detected more frequently in HM patients with glaucoma (71.6%) than in patients without glaucoma (51.6%) (P<0.002). However, the visualization of CZH was not related to the presence of glaucoma in multivariate regression analysis (odds ratio [OR], 0.688; 95% confidence interval [CI], 0.328-1.444; P=0.322). Moreover, compared to the annular pattern used as a reference, triangular and irregular patterns were not associated with the presence of glaucoma (OR: 1.043, 95% CI: 0.101-10.763, P=0.971; OR: 0.527, 95% CI: 0.255-1.092, P=0.085, respectively). MvD was significantly higher in patients with glaucoma (61.2%) than that in patients without glaucoma (2.2%) (P<0.001) and was identified as a significant factor affecting the presence of glaucoma (OR, 42.120; 95% CI, 9.416-188.413; P<0.001). AXL showed a significant correlation with CZH distance in all patients (R=0.399; P<0.001).

Conclusions: CZH was more commonly detected in HM patients with glaucoma. However, no clear associations of glaucoma with the visualization, pattern, or location of CZH were observed in the present study. The correlation between AXL and CZH distance in eyes with HM warrants further investigation. These results may offer insights into the pathogenesis of glaucoma in eyes with HM as OCTA technology advances.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Glaucoma
Journal of Glaucoma 医学-眼科学
CiteScore
4.20
自引率
10.00%
发文量
330
审稿时长
4-8 weeks
期刊介绍: The Journal of Glaucoma is a peer reviewed journal addressing the spectrum of issues affecting definition, diagnosis, and management of glaucoma and providing a forum for lively and stimulating discussion of clinical, scientific, and socioeconomic factors affecting care of glaucoma patients.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信