与对照组相比,评估无青光眼的假性角膜剥脱综合征患者的黄斑内层、环毛细血管视网膜神经纤维层和最小边缘宽度厚度。

IF 2 4区 医学 Q2 OPHTHALMOLOGY
Journal of Glaucoma Pub Date : 2024-11-01 Epub Date: 2024-08-02 DOI:10.1097/IJG.0000000000002471
Ali Azimi, Pardis Bostanian, Mohammad Hassan Jalalpour, Hamid Reza Hassanipour, Jay Chhablani, Elham Sadeghi
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引用次数: 0

摘要

准确性:目的:与健康人相比,评估非青光眼假性角膜外翻综合征(XFS)患者的黄斑内层、环毛细血管视网膜神经纤维层(cp-RNFL)和最小边缘宽度(MRW):在这项前瞻性研究中,使用带青光眼模块高级版的海德堡 Spectralis 光学相干断层扫描(OCT),导出黄斑内层的 8×8 网格,并使用全层、上层和下层厚度。此外,在偏差图上,还分析了眼窝周围的椭圆环,其大小为 4.8×4 毫米。此外,两组均计算了三个上扇区和三个下扇区的 cp-RNFL 和 MRW 值:结果:32 名临床检测出患有非青光眼性 XFS 的受试者的 32 只眼睛和 30 名年龄性别匹配的健康对照者的右眼被纳入研究。病例组和对照组的眼压(IOP)无明显差异(分别为 14.94±2.09 mmHg 对 15.27±2.27,P 值= 0.556)。与对照组相比,XFS 组超颞节段的 MRW(MRW-TS)明显变薄(303.69±60.49 µm vs. 341.43±56.19 µm,P = 0.014)。两组间其他部分的MRW、黄斑内层和cp-RNFL厚度无明显差异:这些研究结果表明,MRW,尤其是颞上区的MRW,可显示非青光眼性XFS患者的早期眼部损伤,并可用于检测XFS患者的早期青光眼。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the Inner Macula Layers, Circumpapillary Retinal Nerve Fiber Layer, and Minimum Rim Width Thickness in Patients With Pseudoexfoliation Syndrome Without Glaucoma Compared With Controls.

Prcis: Minimum rim width (MRW) is thinner in patients with non-glaucomatous pseudoexfoliation syndrome (XFS) and may be the first parameter affected in these patients due to the vascular nature of this disease.

Objective: To evaluate the macular inner layers, circumpapillary retinal nerve fiber layer (cp-RNFL), and MRW in non-glaucomatous XFS compared with healthy patients.

Patients and methods: In this prospective study, using Heidelberg Spectralis optical coherence tomography with Glaucoma Module Premium Edition, 8×8 grids of macular inner layers were exported, and the global, superior, and inferior thicknesses were used. Also, on the deviation map, the elliptical annulus around the fovea, which was 4.8×4 mm in size, was analyzed. Moreover, both groups calculated cp-RNFL and MRW values in 3 superior and 3 inferior sectors.

Results: Thirty-two eyes of 32 patients with clinically detected non-glaucomatous XFS and 30 right eyes of age-sex-matched healthy controls were included. No significant difference was found between the case and control groups concerning the intraocular pressure (14.94 ± 2.09 vs 15.27 ± 2.27 mm Hg, respectively, P = 0.556). The MRW of the superotemporal segment (MRW-temporal superior) was significantly thinner in the XFS group compared with the control ones (303.69 ± 60.49 vs 341.43 ± 56.19 µm, P = 0.014). No significant differences were found in the other sectors of MRW, macular inner layers, and cp-RNFL thickness between the groups.

Conclusion: These findings indicate that the MRW, especially in the superotemporal sector, may show early eye damage in patients with non-glaucomatous XFS, and it may be used to detect the early stage of glaucoma in XFS.

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来源期刊
Journal of Glaucoma
Journal of Glaucoma 医学-眼科学
CiteScore
4.20
自引率
10.00%
发文量
330
审稿时长
4-8 weeks
期刊介绍: The Journal of Glaucoma is a peer reviewed journal addressing the spectrum of issues affecting definition, diagnosis, and management of glaucoma and providing a forum for lively and stimulating discussion of clinical, scientific, and socioeconomic factors affecting care of glaucoma patients.
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