Journal of Heart and Lung Transplantation最新文献

{"title":"The occasional heart transplant program.","authors":"Aaron M Williams, Ashish S Shah","doi":"10.1016/j.healun.2025.09.010","DOIUrl":"10.1016/j.healun.2025.09.010","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations.","authors":"Anna K Reed, Olaf Mercier, Juergen Behr, Kavita Dave, Göran Dellgren, Sakhee Kotecha, Jasleen Kukreja, Caroline Landry, Bronwyn Levvey, Haifa Lyster, Orla Morrissey, Siavosh Saatee, Melissa Sanchez, Marc Schecter, James Walsh, Ashley Virginia Fritz, Theresa A Gelzinis, Konrad Hoetzenecker, Sandra Lindstedt, Nandor Marczin, Barbara J Wilkey, Julien Fessler, Brandi Bottiger, Keith Wille, Basil S Nasir, David Gomez-De-Antonio, Marcelo Cypel, Archer Kilbourne Martin","doi":"10.1016/j.healun.2025.07.033","DOIUrl":"https://doi.org/10.1016/j.healun.2025.07.033","url":null,"abstract":"<p><p>The use of extracorporeal life support (ECLS) throughout the perioperative phase of lung transplantation requires nuanced planning and execution by an integrated team of multidisciplinary experts. To date, no multidisciplinary consensus document has examined the perioperative considerations of how to best manage these patients. To address this challenge, this perioperative utilization of ECLS in lung transplantation consensus statement was approved for development by the International Society for Heart and Lung Transplantation Standards and Guidelines Committee. International experts across multiple disciplines, including cardiothoracic surgery, anesthesiology, critical care, pediatric pulmonology, adult pulmonology, pharmacy, psychology, physical therapy, nursing, and perfusion, were selected based on expertise and divided into subgroups examining the preoperative, intraoperative, and postoperative periods. Following a comprehensive literature review, each subgroup developed recommendations to examine via a structured Delphi methodology. Following 2 rounds of Delphi consensus, a total of 50 recommendations regarding preoperative considerations for ECLS in lung transplantation met consensus criteria. These recommendations focus on the criteria for preoperative ECLS as well as select multidisciplinary team management considerations throughout the entire preoperative phase.</p>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S1053-2498(25)02242-9","DOIUrl":"10.1016/S1053-2498(25)02242-9","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 10","pages":"Page A10"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors Insights on the Updated International Society for Heart and Lung Transplantation Guidelines for the Management of Pediatric Heart Failure (Update From 2014)","authors":"Shelley D. Miyamoto ,&nbsp;Claire Irving ,&nbsp;Estela Azeka ,&nbsp;Rachele Adorisio ,&nbsp;Elizabeth D. Blume ,&nbsp;Carmel Bogle ,&nbsp;Henry Chubb ,&nbsp;Jennifer Conway ,&nbsp;Melissa K. Cousino ,&nbsp;Jonathan Edelson ,&nbsp;Katrina Ford ,&nbsp;Paula Holinski ,&nbsp;Jan Janousek ,&nbsp;Ashwin Lal ,&nbsp;Teresa Lee ,&nbsp;Angela Lorts ,&nbsp;Stephanie Nakano ,&nbsp;David N. Rosenthal ,&nbsp;Joseph Rossano","doi":"10.1016/j.healun.2025.06.004","DOIUrl":"10.1016/j.healun.2025.06.004","url":null,"abstract":"<div><div>Pediatric heart failure (HF) secondary to cardiomyopathies, acquired heart disease, and congenital heart disease is associated with significant morbidity and mortality. These guidelines represent an update from the International Society for Heart and Lung Transplantation guidelines for the management of pediatric HF that were published in 2014 and incorporate interval advancements in medical therapies and new approaches in the evaluation and management of children with HF.</div></div>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 10","pages":"Pages 1529-1534"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Passive leg raise during cardiac catheterization work-up for HFpEF: is it worth the trouble?","authors":"Erik Fung MD, PhD","doi":"10.1016/j.healun.2025.05.004","DOIUrl":"10.1016/j.healun.2025.05.004","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 10","pages":"Pages 1555-1556"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145046045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling effective care, empowering discovery: Tackling the tough questions about advanced heart failure in adult congenital heart disease","authors":"Christopher R. Broda MD ,&nbsp;Katherine Kearney MBBS, PhD ,&nbsp;S. Lucy Roche MB ChB, MD (research)","doi":"10.1016/j.healun.2025.06.028","DOIUrl":"10.1016/j.healun.2025.06.028","url":null,"abstract":"<div><div>Many adults with moderate or complex congenital heart disease (CHD) develop chronic heart or circulatory failure syndromes, often becoming clinically apparent in their 30 s, 40 s, or 50 s and carrying a high risk of mortality. Although the pathophysiology of adult congenital heart disease-related heart failure (ACHD-HF) is highly heterogeneous, it is typically characterized by a prolonged pre-symptomatic phase. During this time, chronic compensatory mechanisms mask disease progression, making the severity of the condition difficult to recognize in a timely manner. This clinical challenge is compounded by fragmented care models, limited specialist resources, and persistent knowledge gaps. Consequently, patients are referred late for advanced therapies, contributing to the excess mortality, particularly in the context of transplant.</div><div>While it is recognized that excellent outcomes from transplant and mechanical circulatory support options are achievable in adult CHD patients, contemporary selection practices leave the population undertreated. To advance this cause, we convened a meeting at the 2025 International Society for Heart and Lung Transplantation 45th Annual Meeting &amp; Scientific Sessions in Boston, Massachusetts. The meeting brought together more than 35 participants, including adult and pediatric cardiologists, surgeons, advanced practice providers, researchers, and trainees from North America, Europe and Australia. This diverse group shared opinions regarding priorities for research, education and patient advocacy.</div><div>A widely supported outcome was the development of an ACHD-HF specific professional community under the umbrella of ISHLT. This entity would serve as a collaborative home for those dedicated to addressing the knowledge gaps in ACHD-HF, advancing care, and improving outcomes for this growing and vulnerable population.</div></div>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 10","pages":"Pages 1679-1682"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-in-human operations require more than technical excellence","authors":"Brent K. Winemiller ,&nbsp;Joshua A. Daily ,&nbsp;Paolla G. Anderson ,&nbsp;Taufiek Konrad Rajab","doi":"10.1016/j.healun.2025.06.017","DOIUrl":"10.1016/j.healun.2025.06.017","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 10","pages":"Pages 1672-1673"},"PeriodicalIF":6.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Society for Heart and Lung Transplantation (ISHLT) Consensus Statement on Risk Stratification in Pulmonary Arterial Hypertension","authors":"Sandeep Sahay ,&nbsp;Scott Visovatti ,&nbsp;Adriano R. Tonelli ,&nbsp;Nelson Villasmil Hernandez ,&nbsp;Eric D. Austin ,&nbsp;Roberto Badagliacca ,&nbsp;Rolf M.F. Berger ,&nbsp;Athénaïs Boucly ,&nbsp;Yucheng Chen ,&nbsp;Colin Church ,&nbsp;Marion Delcroix ,&nbsp;Allen D. Everett ,&nbsp;Harrison W. Farber ,&nbsp;Charles Fauvel ,&nbsp;Mardi Gomberg-Maitland ,&nbsp;Megan Griffiths ,&nbsp;Francois Haddad ,&nbsp;Yuchi Han ,&nbsp;Anna Hemnes ,&nbsp;Marius M. Hoeper ,&nbsp;Raymond L. Benza","doi":"10.1016/j.healun.2025.04.015","DOIUrl":"10.1016/j.healun.2025.04.015","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":"44 11","pages":"Pages e73-e131"},"PeriodicalIF":6.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to 'Pragmatic approach to temporary mechanical circulatory support in acute right ventricular failure' [J Heart Lung Transplant (2024) 1894-1904].","authors":"Anthony P Carnicelli, Sean van Diepen, Ann Gage, Alexander M Bernhardt, Jennifer Cowger, Brian A Houston, Matt T Siuba, Rachna Kataria, Craig J Beavers, Kevin J John, Bart Meyns, Navin K Kapur, Ryan J Tedford, Manreet Kanwar","doi":"10.1016/j.healun.2025.08.008","DOIUrl":"https://doi.org/10.1016/j.healun.2025.08.008","url":null,"abstract":"","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144956918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Center experience is associated with greater survival following donation after circulatory death heart transplantation.","authors":"Brian E Woolley, Yeahwa Hong, Umar Nasim, Nidhi Iyanna, Ander Dorken-Gallastegi, Samantha N Machinski, Gavin W Hickey, Mary E Keebler, Edward T Horn, David J Kaczorowski","doi":"10.1016/j.healun.2025.08.015","DOIUrl":"10.1016/j.healun.2025.08.015","url":null,"abstract":"<p><strong>Background: </strong>Higher center volume has been associated with improved outcomes in solid organ transplantation. However, the impact of center experience on donation after circulatory death (DCD) heart transplantation outcomes remains unclear. This study evaluates the association between cumulative DCD center experience and DCD post-transplant survival.</p><p><strong>Methods: </strong>The United Network for Organ Sharing registry was queried for adult recipients who underwent DCD heart transplantation from January 1, 2019 to December 31, 2023. Recipients were stratified by cumulative DCD center experience into low (≤10), intermediate (11-24), and high (≥25) transplant volume centers. The primary outcome was 1-year post-transplant survival. A restricted cubic spline (RCS) model was used to assess the volume-outcome relationship.</p><p><strong>Results: </strong>A total of 1,114 DCD heart transplant recipients across 59 centers were included. Low cumulative DCD volume was associated with lower 1-year DCD post-transplant survival compared to high-volume centers when controlling for confounders (89.0% vs 92.9%, p = 0.025), independent of donation after brain death (DBD) center volume and center-level DBD post-transplant survival. RCS showed decreasing 1-year post-transplant mortality with increasing DCD volume up to 20 DCD cases, beyond which survival gains plateaued. Normothermic regional perfusion was associated with similar survival compared to direct procurement and perfusion across all center volume categories.</p><p><strong>Conclusions: </strong>Higher cumulative DCD center experience is associated with improved 1-year DCD post-transplant survival independent of DBD center volume or performance. Survival gains plateau after approximately 20 cumulative DCD cases. These findings highlight the importance of DCD-specific institutional experience and support the expansion of DCD heart transplantation to more centers while maintaining favorable outcomes.</p>","PeriodicalId":15900,"journal":{"name":"Journal of Heart and Lung Transplantation","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144956888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}