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From the Editor’s Desk... 从编辑部…
IF 26.8 1区 医学
Journal of Hepatology Pub Date : 2025-05-15 DOI: 10.1016/j.jhep.2025.03.012
Philip Newsome, Frank Tacke, Heiner Wedemeyer, Lorenza Rimassa, Annalisa Berzigotti, Tom H. Karlsen, Vlad Ratziu
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引用次数: 0
Discover the EASL DeepDive, a free educational webinar series offering an in-depth exploration of specific topics in hepatology and liver research 探索EASL DeepDive，这是一个免费的教育网络研讨会系列，提供了对肝病学和肝脏研究特定主题的深入探索
IF 26.8 1区 医学
Journal of Hepatology Pub Date : 2025-05-15 DOI: 10.1016/S0168-8278(25)00258-2
{"title":"Discover the EASL DeepDive, a free educational webinar series offering an in-depth exploration of specific topics in hepatology and liver research","authors":"","doi":"10.1016/S0168-8278(25)00258-2","DOIUrl":"10.1016/S0168-8278(25)00258-2","url":null,"abstract":"","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"82 6","pages":"Page iv"},"PeriodicalIF":26.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Join the community and become an EASL member today! 今天就加入EASL社区，成为EASL会员吧！
IF 26.8 1区 医学
Journal of Hepatology Pub Date : 2025-05-15 DOI: 10.1016/S0168-8278(25)00257-0
{"title":"Join the community and become an EASL member today!","authors":"","doi":"10.1016/S0168-8278(25)00257-0","DOIUrl":"10.1016/S0168-8278(25)00257-0","url":null,"abstract":"","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"82 6","pages":"Page iii"},"PeriodicalIF":26.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The EASL Guidelines app is your indispensable mobile companion for accessing comprehensive and up-to-date clinical practice guidelines in hepatology. Download it now! EASL指南应用程序是您访问肝病学全面和最新临床实践指南不可或缺的移动伴侣。现在就下载吧！
IF 26.8 1区 医学
Journal of Hepatology Pub Date : 2025-05-15 DOI: 10.1016/S0168-8278(25)00256-9
{"title":"The EASL Guidelines app is your indispensable mobile companion for accessing comprehensive and up-to-date clinical practice guidelines in hepatology. Download it now!","authors":"","doi":"10.1016/S0168-8278(25)00256-9","DOIUrl":"10.1016/S0168-8278(25)00256-9","url":null,"abstract":"","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"82 6","pages":"Page ii"},"PeriodicalIF":26.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DECISION is an international, EU-funded research project on decompensated cirrhosis to identify new combinatorial therapies based on systems approaches. Discover the project! DECISION是一项由欧盟资助的国际研究项目，研究失代偿性肝硬化，以确定基于系统方法的新组合疗法。发现项目！
IF 26.8 1区 医学
Journal of Hepatology Pub Date : 2025-05-15 DOI: 10.1016/S0168-8278(25)00259-4
{"title":"DECISION is an international, EU-funded research project on decompensated cirrhosis to identify new combinatorial therapies based on systems approaches. Discover the project!","authors":"","doi":"10.1016/S0168-8278(25)00259-4","DOIUrl":"10.1016/S0168-8278(25)00259-4","url":null,"abstract":"","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"82 6","pages":"Page v"},"PeriodicalIF":26.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing five-year overall survival as a new standard for trials in advanced HCC 建立5年总生存期作为晚期HCC临床试验的新标准
IF 25.7 1区 医学
Journal of Hepatology Pub Date : 2025-05-13 DOI: 10.1016/j.jhep.2025.05.001
Pierre Nahon
{"title":"Establishing five-year overall survival as a new standard for trials in advanced HCC","authors":"Pierre Nahon","doi":"10.1016/j.jhep.2025.05.001","DOIUrl":"https://doi.org/10.1016/j.jhep.2025.05.001","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Disclosures</h2>Pr Nahon has received honoraria from and/or consults for AstraZeneca, Bristol-Myers Squibb, Eisai, and Roche. He received research grants from AstraZeneca, Bristol-Myers Squibb and Eisai.</section></section><section><section><h2>Grant Support</h2>Pierre Nahon’s research is funded in part by the European Union (GENIAL, Grant agreement ID: 101096312), French Agence Nationale de la Recherche (France 2030 DELIVER ANR-21-RHUS-0001) and by France 2030 RHU LIVER-TRACK (ANR-23-RHUS-0014).</section></section><section><section><h2>Declaration of Competing Interest</h2>none to declare</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"55 29 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143940273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why One PEth Result Cannot Redraw the MASLD/ALD Boundary: A Single-Snapshot Misclassification 为什么一个PEth结果不能重新绘制MASLD/ALD边界：单快照分类错误
IF 25.7 1区 医学
Journal of Hepatology Pub Date : 2025-05-13 DOI: 10.1016/j.jhep.2025.05.002
Tao Zhang
{"title":"Why One PEth Result Cannot Redraw the MASLD/ALD Boundary: A Single-Snapshot Misclassification","authors":"Tao Zhang","doi":"10.1016/j.jhep.2025.05.002","DOIUrl":"https://doi.org/10.1016/j.jhep.2025.05.002","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Authors' contributions</h2>Tao Zhang is the only author of this letter and made all contributions.</section></section><section><section><h2>Financial support</h2>This letter receives no financial support.</section></section><section><section><h2>Declaration of Competing Interest</h2>There is no conflict of interest.Please refer to the accompanying ICMJE disclosure forms for further details.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"26 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143940272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EASL Clinical Practice Guidelines on the management of extrahepatic cholangiocarcinoma EASL肝外胆管癌治疗临床实践指南
IF 25.7 1区 医学
Journal of Hepatology Pub Date : 2025-05-10 DOI: 10.1016/j.jhep.2025.03.007
{"title":"EASL Clinical Practice Guidelines on the management of extrahepatic cholangiocarcinoma","authors":"","doi":"10.1016/j.jhep.2025.03.007","DOIUrl":"https://doi.org/10.1016/j.jhep.2025.03.007","url":null,"abstract":"Recent years have witnessed significant advances in the imaging, molecular profiling, and systemic treatment of cholangiocarcinoma (CCA). Despite this progress, the early detection, precise classification, and effective management of CCA remain challenging. Owing to recent developments and the significant differences in CCA subtypes, EASL commissioned a panel of experts to draft evidence-based recommendations on the management of extrahepatic CCA, comprising distal and perihilar CCA. Particular attention is given to the need for accurate classification systems, the integration of emerging molecular insights, and practical strategies for diagnosis and treatment that reflect real-world clinical scenarios.","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"27 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EASL Clinical Practice Guidelines on the management of autoimmune hepatitis EASL自身免疫性肝炎管理临床实践指南
IF 25.7 1区 医学
Journal of Hepatology Pub Date : 2025-05-10 DOI: 10.1016/j.jhep.2025.03.017
{"title":"EASL Clinical Practice Guidelines on the management of autoimmune hepatitis","authors":"","doi":"10.1016/j.jhep.2025.03.017","DOIUrl":"https://doi.org/10.1016/j.jhep.2025.03.017","url":null,"abstract":"Autoimmune hepatitis (AIH) is a chronic liver disease of unknown aetiology which may affect any patient irrespective of age, sex, and ethnicity. At baseline, the clinical spectrum of the disease varies largely from asymptomatic cases to acute liver failure with massive hepatocyte necrosis. The aim of these EASL guidelines is to provide updated guidance on the diagnosis and management of AIH both in adults and children. Updated guidance on the management of patients with variants and specific forms of AIH is also provided, as is detailed guidance on the management of AIH-associated cirrhosis, including surveillance for portal hypertension and hepatocellular carcinoma, as well as liver transplantation in decompensated cirrhosis.","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"39 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EASL Clinical Practice Guidelines on extrahepatic abdominal surgery in patients with cirrhosis and advanced chronic liver disease 肝硬化和晚期慢性肝病患者肝外腹部手术的EASL临床实践指南
IF 25.7 1区 医学
Journal of Hepatology Pub Date : 2025-05-10 DOI: 10.1016/j.jhep.2025.04.008
{"title":"EASL Clinical Practice Guidelines on extrahepatic abdominal surgery in patients with cirrhosis and advanced chronic liver disease","authors":"","doi":"10.1016/j.jhep.2025.04.008","DOIUrl":"https://doi.org/10.1016/j.jhep.2025.04.008","url":null,"abstract":"Extrahepatic surgery in patients with cirrhosis of the liver represents a growing clinical challenge due to the increasing prevalence of chronic liver disease and improved long-term survival of these patients. The presence of cirrhosis significantly increases the risk of perioperative morbidity and mortality following abdominal surgery. Advances in preoperative risk stratification, surgical techniques, and perioperative care have led to better outcomes, yet integration of these improvements into routine clinical practice is needed. These clinical practice guidelines provide comprehensive recommendations for the assessment and perioperative management of patients with cirrhosis undergoing extrahepatic surgery. An individualised patient-centred risk assessment by a multidisciplinary team including hepatologists, surgeons, anaesthesiologists, and other support teams is essential.","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"109 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143931081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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