{"title":"Response to: Highlighting the Impact of Hormonal Factors on Hepatic Cystogenesis: Implications for Pathophysiology and Clinical Practice","authors":"Renée Duijzer, Tom JG. Gevers, Joost PH. Drenth","doi":"10.1016/j.jhep.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.12.001","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Authors' contributions:</h2>all authors contributed equally to this work</section></section><section><section><h2>Financial support:</h2>not applicable.We would like to express our appreciation to Catania et al. for their thorough commentary on the role of hormonal factors in polycystic liver disease (PLD) 1, 2. The authors effectively bolster the case for the role of estrogens in formation and growth of liver cysts in PLD. The striking sex imbalance in PLD, as highlighted by the authors, underscores the need to address hormonal influences not only as a matter of understanding pathophysiology, but also as practical consideration</section></section><section><section><h2>Declaration of Competing Interest:</h2>no conflict of interest</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"18 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142763305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacological inhibition of ATGL as therapeutic approach for MASH: Far beyond the lipase suppression role of ATGL inhibitors","authors":"Tianhao Ying, Yuxiao Han, Mengyang Liu","doi":"10.1016/j.jhep.2024.11.048","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.048","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Declaration of Competing Interest</h2>The authors disclose no conflicts.</section></section><section><section><h2>Financial support</h2>This work was supported by the National Natural Science Foundation of China (No. 82004062), the Young Elite Scientists Sponsorship Program by CACM (No. 2021-QNRC2-B12)</section></section><section><section><h2>Authors contributions</h2>TY: initial drafting of the manuscript. YH: revision of the manuscript. ML: conception and revision and final approval of the manuscript. All the authors approved the final version of the letter.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"14 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142763303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correspondence on “Hepatic venous pressure gradient predicts risk of hepatic decompensation and liver-related mortality in patients with MASLD”","authors":"Yuting Guan, Qiongguang Huang","doi":"10.1016/j.jhep.2024.11.047","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.047","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Disclosures</h2>None.</section></section><section><section><h2>Author contribution</h2>Yuting Guan: Project administration, Writing - Original draft preparation.Qiongguang Huang: Project administration, Writing – Original Review & Editing.</section></section><section><section><h2>Funding</h2>Not applicable.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"82 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142763304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain-to-gut control of fat absorption: Implications for metabolic liver diseases","authors":"Valerie Chew","doi":"10.1016/j.jhep.2024.10.035","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.10.035","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Financial support</h2>This work was supported by the <span>National Medical Research Council (NMRC), Singapore</span> (reference number: CIRG22jul-0025, NMRC/OFLCG/003/2018), <span>National Research Foundation, Singapore</span> (ref number: NRF-CRP26-2021-0005) and <span>International Gilead Sciences Research Scholars Program in Liver Disease – Asia</span>.</section></section><section><section><h2>Conflict of interest</h2>The author of this study declares that they do not have any conflict of interest.Please refer to the accompanying ICMJE disclosure forms for further details.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"12 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reconciling the apparently contrasting observational and genetic evidence on the association between MASLD and cardiovascular disease","authors":"Martijn C.G.J. Brouwers","doi":"10.1016/j.jhep.2024.11.042","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.042","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Financial support statement</h2>none</section></section><section><section><h2>Declaration of Competing Interest</h2>MCGJB received honoraria for a lecture for the International Congress on Lipid and Atherosclerosis (paid to institution)</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"84 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to “The incidence of hepatitis flare and hepatic decompensation after nucleos(t)ide analogue cessation in chronic hepatitis B patients.”","authors":"Edo J. Dongelmans, Harry L.A. Janssen","doi":"10.1016/j.jhep.2024.11.044","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.044","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Clinical trial number</h2>not applicable.</section></section><section><section><h2>Author contributions</h2>Edo Dongelmans, MD (Conceptualization: Equal; Writing – original draft: Lead). Harry L.A. Janssen, MD, PhD (Conceptualization: Equal; Supervision: Lead; Writing – review & editing: Equal).</section></section><section><section><h2>Data availability statement</h2>not applicable.</section></section><section><section><h2>Financial support</h2>No funding was received for this article.</section></section><section><section><h2>Declaration of Competing Interest:</h2>Edo Dongelmans has no conflicts of interests. Harry Janssen received grants from: Gilead Sciences, GlaxoSmithKline, Janssen, Roche, Vir Biotechnology Inc. and is consultant for: Aligos, Gilead Sciences, GlaxoSmithKline, Janssen, Roche, Vir Biotechnology Inc., Precision Biosciences, Griffols.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"27 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to: “Could the paediatric acute hepatitis of unknown origin be related to a new autoimmune disease?”","authors":"Tatsuya Okamoto, Etsuro Hatano","doi":"10.1016/j.jhep.2024.11.045","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.045","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Conflict of Interest Disclosures (includes financial disclosures):</h2>The authors declare no conflicts of interest associated with this study. The authors declare no financial relationships relevant to this article.</section></section><section><section><h2>Contributors’ Statement Page</h2>Dr. Okamoto drafted the initial manuscript, and reviewed and revised the manuscript. Prof. Hatano critically reviewed and revised the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.</section></section><section><section><h2>Funding/Support:</h2>No funding was secured for this study.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"259 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comprehensive Framework for Investigating Oral-Gut Microbiome Dynamics: From Normal Variation to Pathological Changes","authors":"Huiwu Xing, Di Huang, Chen Xue","doi":"10.1016/j.jhep.2024.11.036","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.036","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Author’s contributions</h2>Huiwu Xing: Study design & Manuscript Writing.Di Huang and Chen Xue: Study design & Manuscript Revision.</section></section><section><section><h2>Declaration of Competing Interest</h2>We declare there is no any conflict of interest.</section></section><section><section><h2>Acknowledgements & Funding</h2>This work was supported by the China Postdoctoral Science Foundation (2023M743200 and 2024T170826), the Postdoctoral Fellowship Program of CPSF (GZC20232425), the Henan Medical Science and Technology Joint Building Program (LHGJ20240211 and LHGJ20240335), and the Henan Sunshine Medical Health Development Foundation iGanDan Project (HKP2023001 and HKP2023006).</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"7 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tharun Tom Oommen, Rizwan Ahamed, Cyriac Abby Philips
{"title":"Missing the forest for the trees: time to address stool microbial load and everything else that realistically matters in microbiome studies","authors":"Tharun Tom Oommen, Rizwan Ahamed, Cyriac Abby Philips","doi":"10.1016/j.jhep.2024.11.037","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.037","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Authors’ contributions</h2>TTO designed the study and wrote the manuscript, CAP and RA reviewed the paper and made critical revisions. All authors accepted the final version of manuscript for submission.</section></section><section><section><h2>Financial support</h2>The authors received no financial support to produce this manuscript.</section></section><section><section><h2>Declaration of Competing Interest</h2>The authors declare no conflicts of interest that pertain to this work.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"22 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plasma metabolomics promises to facilitate precise prevention of MASH and mortality from liver disease","authors":"Xin Xu, Ping Liu, Peipei Zhang","doi":"10.1016/j.jhep.2024.11.038","DOIUrl":"https://doi.org/10.1016/j.jhep.2024.11.038","url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Financial support</h2>This study was supported by Shanghai Jiao Tong University School of Medicine: Nursing Development Program (SJTUHLXK2024).</section></section><section><section><h2>Authors’ contributions</h2>All authors contributed to the drafting and revision of this letter.</section></section><section><section><h2>Declaration of Competing Interest</h2>The authors of this study declare that they do not have any conflict of interest.</section></section>","PeriodicalId":15888,"journal":{"name":"Journal of Hepatology","volume":"27 1","pages":""},"PeriodicalIF":25.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142742670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}