Journal of Food Bioactives最新文献_第10页

Functional Foods Beyond Nutrition: Therapeutic Interventions to Combat COVID-19 and Other Viral Diseases 营养之外的功能食品:对抗COVID-19和其他病毒性疾病的治疗干预措施

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15283

S. Banik, R. Ghosh, B. Downs, Sanjoy Chakraborty, M. Bagchi, Tandra R. Chakraborty, D. Bagchi

{"title":"Functional Foods Beyond Nutrition: Therapeutic Interventions to Combat COVID-19 and Other Viral Diseases","authors":"S. Banik, R. Ghosh, B. Downs, Sanjoy Chakraborty, M. Bagchi, Tandra R. Chakraborty, D. Bagchi","doi":"10.31665/jfb.2021.15283","DOIUrl":"https://doi.org/10.31665/jfb.2021.15283","url":null,"abstract":"SARS-COV2 has emerged as the second biggest threat to humanity of all times, after the Spanish Flu massacre. Due to its brisk rate of mutation, especially that of the host receptor docking Spike protein, a safe immunization is still questioned by some, and protection or recovery has been dependent largely on immune system competence and overall bio-constitutional strength. In order to ensure optimal performance of the body’s immune cells, proper nutrition fortified with functional food ingredients is indispensable. Especially in a scenario where targeted therapeutics against life threatening pandemics like SARS-CoV2 are yet to be invented, formulation of dietary supplements rich in antioxidants, vitamins, and minerals is the need of the hour to promote greater immuno-competence and a heightened immune response; decrease the overall metabolic burden; and restore homeostasis in an infected individual. This review highlights our current understanding and advances made in the regimen of functional foods designed to combat viral diseases together with the shortcomings involved therein.","PeriodicalId":15882,"journal":{"name":"Journal of Food Bioactives","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88545075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Phytochemicals: Potential Lead Compounds for COVID-19 Therapeutics 植物化学物质:2019冠状病毒病治疗的潜在先导化合物

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15279

S. Kashyap, Revathy Nadhan, D. Dhanasekaran

{"title":"Phytochemicals: Potential Lead Compounds for COVID-19 Therapeutics","authors":"S. Kashyap, Revathy Nadhan, D. Dhanasekaran","doi":"10.31665/jfb.2021.15279","DOIUrl":"https://doi.org/10.31665/jfb.2021.15279","url":null,"abstract":"Coronavirus Disease 2019 (COVID-19) is a global pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). The rising number of cases of this highly transmissible infection has pressed for the urgent need to find effective therapeutics. The life cycle of SARS-CoV-2 includes the viral entry, viral replication, viral assembly and release. The symptoms associated with viral infection often leads to fatal outcome with pneumonia, myocarditis, acute respiratory distress syndrome, hypercoagulability, and/or multi-organ failure. Recent studies have reported that phytochemicals such as emodin, epigallocatechin gallate, and berberine could, albeit modestly, inhibit different stages of SARS-CoV-2 life cycle. The phytochemicals have been shown to disrupt viral infection and replication by blocking viral-surface spike protein binding to entry receptor angiotensin-converting enzyme (ACE2), inhibiting viral membrane fusion with host cells, inhibiting RNA-dependent RNA polymerase involved in viral replication, and/or pathological host- responses in vitro. The focus of this review is to evaluate the efficacies of these phytochemicals on inhibiting SARS-CoV-2 viral infection, growth, or disease progression as well as to provide a perspective on the potential use of these phytochemicals in the development of novel therapeutics against SARS-CoV-2","PeriodicalId":15882,"journal":{"name":"Journal of Food Bioactives","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80810865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Potential adverse health effects of dietary lipid oxidation products 膳食脂质氧化产物对健康的潜在不利影响

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15282

Yuanyuan Hu, Guanhua Zhao, M. Zhang, Da‐yong Zhou, B. Zhu

引用次数: 4

Optimized preparation of quassinoids rich Eurycoma longifolia Jack, TAF2-phospholipid complex and its effects on oral bioavailability 富拟西番莲的优化制备及其对taf2 -磷脂复合物的口服生物利用度的影响

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15285

Wu Guo, Shu-yan Wang, Jian Ren, Bo Zhang

{"title":"Optimized preparation of quassinoids rich Eurycoma longifolia Jack, TAF2-phospholipid complex and its effects on oral bioavailability","authors":"Wu Guo, Shu-yan Wang, Jian Ren, Bo Zhang","doi":"10.31665/jfb.2021.15285","DOIUrl":"https://doi.org/10.31665/jfb.2021.15285","url":null,"abstract":"Eurycoma longifolia Jack is a plant of the genus Eurycoma in Simaroubaceae. Eurycomanone is one of the main quassinoids of E. longifolia. Unfortunately, these quassinoids exhibit low bioavailability . In the present study, a phospholipid complex (TAF2-PC) was prepared to improve the oral bioavailability of TAF2 (Tongkat Ali Fraction 2). The complexation rate of eurycomanone and phospholipid was used as the index of success in the phospholipid complexes. The effects of reaction solvent, reaction temperature, drug concentration, drug-lipid ratio and reaction time on thecomplexation rate were investigated. Response Surface-Box-Behnken Design Method was performed to optimize the preparation technology and the pharmacokinetics of phospholipid complex of TAF2 were studied in rats. Our results showed that the optimum preparation condition of TAF2-phospholipid complex were as follows: reaction solvent, anhydrous ethanol; reaction time, 1 h; the ratio of TAF2 to phospholipid, 2.28; reaction temperature, 40.85 ℃; TAF2 concentration, 32.66 mg/ml; and complexation rate, 95.04 ± 0.4% (n=3).The results of pharmacokinetic study showed that the relative bioavailability was increased to 209.20% in the TAF2-phospholipid complex-treated rats.Thus,this phospholipid-complex-technique shows potential for enhancing oral bioavailability of poorly absorbed quassinoid-rich E. longifolia extract, TAF2.","PeriodicalId":15882,"journal":{"name":"Journal of Food Bioactives","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76262092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Is the gluten-free and casein-free diet efficacious in the treatment of childhood autism spectrum disorder? 无麸质和无酪蛋白饮食对儿童自闭症谱系障碍的治疗有效吗?

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15277

K. Lange, A. Reissmann

{"title":"Is the gluten-free and casein-free diet efficacious in the treatment of childhood autism spectrum disorder?","authors":"K. Lange, A. Reissmann","doi":"10.31665/jfb.2021.15277","DOIUrl":"https://doi.org/10.31665/jfb.2021.15277","url":null,"abstract":"Autism spectrum disorder (ASD) is a set of heterogeneous neurodevelopmental conditions, characterized by early-onset difficulties in social communication as well as repetitive and unusually restricted behaviors and interests. The treatment of ASD is based primarily on psychoeducational and behavioral interventions. Since the effectiveness of available treatments for ASD is limited, many families search for alternative therapies, such as the gluten-free and casein-free (GFCF) diet. Despite the popularity of the GFCF diet as a supplementary treatment in children with ASD, several rigorous evaluations have failed to confirm its effectiveness. The majority of the available studies examining the efficacy of the GFCF diet are seriously flawed and allow no firm conclusions. The available evidence regarding the effectiveness of the GFCF diet in the treatment of childhood ASD is very weak and cannot be considered promising. The GFCF diet should be used only if an allergy or intolerance to nutritional gluten or casein has been established. The identification of a hypothetical diet-related ASD phenotype may help in selecting children who could benefit from a GFCF dietary intervention. An important consideration is that potentially ineffective therapies may imply considerable opportunity costs, with other possibly more effective treatment approaches remaining unutilized.","PeriodicalId":15882,"journal":{"name":"Journal of Food Bioactives","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75610022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phenolic compounds in cereal grains and effects of processing on their composition and bioactivities: A review 谷物中酚类化合物及其加工对其组成和生物活性的影响

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15281

F. Shahidi, Renan Danielski, Chiaki Ikeda

引用次数: 4

The use of vitamin D in depression 维生素D在抑郁症中的应用

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15278

Klaus W. Lange, K. Lange, Yukiko Nakamura, A. Reissmann

{"title":"The use of vitamin D in depression","authors":"Klaus W. Lange, K. Lange, Yukiko Nakamura, A. Reissmann","doi":"10.31665/jfb.2021.15278","DOIUrl":"https://doi.org/10.31665/jfb.2021.15278","url":null,"abstract":"Vitamin D has increasingly been associated with the pathophysiology of mental illness and has been suggested to have beneficial effects on depression in adults. Epidemiological studies concerning vitamin D and depression have found inconsistent results and many have significant methodological limitations. The available evidence suggests that depressed individuals show reduced vitamin D concentrations compared to controls without depression. Despite the available findings suggesting that hypovitaminosis D elevates the risk of depressive mood, the evidence of observational and interventional studies is insufficient to establish causality between low vitamin D levels and the occurrence of depression. The question of whether vitamin D sufficiency has protective efficacy against incident depression or recurrence requires future investigation. In order to examine the therapeutic efficacy of vitamin D, further well-designed, large-scale, long-term intervention trials of vitamin D supplementation in people of different age groups with depressive symptoms, diagnosed depression, postpartum depression or other depressive disorders are warranted. In short, current evidence cannot definitively establish whether vitamin D deficiency is a risk factor in the development of depression or whether vitamin D is effective in the treatment of depression.","PeriodicalId":15882,"journal":{"name":"Journal of Food Bioactives","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90882278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Consumer Behaviour and Healthy Diet: A Challenge or an Opportunity? 消费者行为与健康饮食:挑战还是机遇?

Journal of Food Bioactives Pub Date : 2021-09-30 DOI: 10.31665/jfb.2021.15276

F. Shahidi

引用次数: 0

Do traditional food cultures play a role in COVID-19 for health and immunity? 传统饮食文化在COVID-19的健康和免疫中发挥作用吗?

Journal of Food Bioactives Pub Date : 2021-07-01 DOI: 10.31665/JFB.2021.14274

F. Shahidi

引用次数: 1

Correction: In-vitro antidiabetic activities, chemical compositions, antioxidant activities, and toxicity of black tea polysaccharides as a potential source of dietary ingredients 更正:体外抗糖尿病活性、化学成分、抗氧化活性和红茶多糖作为膳食成分的潜在来源的毒性

Journal of Food Bioactives Pub Date : 2021-06-30 DOI: 10.31665/jfb.2021.14275

E. Pelvan, A. Karadaǧ, K. Dogan, S. Aksu, A. Taş, K. Akalın, Özlem A. Eklioğlu, C. Alasalvar

引用次数: 0