Journal of Gastroenterology and Hepatology最新文献

{"title":"Detection of Helicobacter pylori Infection and Antibiotic Resistance via String Test Coupled With qPCR Method: A Comparative Methodological Study.","authors":"Yu-Ting Si, Xue-Song Xiong, Shen-Ke Zhang, Jin-Xin Lai, Yu-Ting Li, Zeeshan Umar, Luan Luan, Jia-Wei Tang, Zheng-Kang Li, Fen Li, Bing Gu, Liang Wang","doi":"10.1111/jgh.16962","DOIUrl":"https://doi.org/10.1111/jgh.16962","url":null,"abstract":"<p><strong>Background and aim: </strong>Helicobacter pylori (H. pylori) infection has long been a significant global public health concern, with antibiotic resistance becoming increasingly severe. Gastric fluid qPCR detection can provide information on H. pylori infection and antibiotic resistance.</p><p><strong>Methods: </strong>This study compares a series of diagnostic methods among 300 participants to reveal best practices for detecting H. pylori infection and/or profiling antibiotic resistance, including urea breath test (UBT), rapid urease test (RUT), gastric mucosa qPCR (GM-qPCR), and the novel gastric fluid qPCR (GF-qPCR).</p><p><strong>Results: </strong>The infection rates detected by UBT and RUT were 32.33% and 23.33%, respectively. Through qPCR analysis, the infection rates in gastric fluid and gastric mucosal were 27.67% and 25.33%. When comparing three methods of detecting H. pylori using the UBT as the reference standard, it was found that the sensitivity, specificity, positive and negative predictive values, and accuracy of gastric fluid qPCR performed the best. The consistency of the four methods was assessed using the Kappa value, which yielded a value of 0.792. Additionally, 45 individuals showed inconsistent results. When using qPCR to detect antibiotic resistance in gastric fluid and gastric mucosal samples, we observed resistance rates of 42.17% (35/83) for clarithromycin and 49.40% (41/83) for levofloxacin in gastric fluid samples. In contrast, resistance rates in gastric mucosal tissue samples were significantly lower at 16.87% (14/76) for clarithromycin and 22.37% (17/76) for levofloxacin.</p><p><strong>Conclusions: </strong>The GF-qPCR method is a promising technique for detecting H. pylori infection and antibiotic resistance, with the potential for providing guided treatment plans.</p>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Trial: The Optimal Timing of the Endoscope Insertion After Oral Lidocaine Spray. A Randomized Controlled Trial","authors":"Hsueh-Chien Chiang,&nbsp;Chien-Ming Chiang,&nbsp;Wei-Lun Chang,&nbsp;Meng-Ying Lin","doi":"10.1111/jgh.16958","DOIUrl":"10.1111/jgh.16958","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aim</h3>\u0000 \u0000 <p>Esophagogastroduodenoscopy (EGD) is a critical diagnostic tool for assessing upper gastrointestinal disorders, yet it can induce significant discomfort due to gag reflexes and pain. For patients with a higher risk for sedation, topical lidocaine spray at the hypopharynx is an alternative method. Yet, no standardized protocol exists regarding the optimal waiting period between administering lidocaine spray and commencing EGD. This study investigates the optimal waiting time between the application of topical lidocaine spray and the initiation of EGD to enhance patient comfort and procedural efficacy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Conducted as a single-center randomized controlled trial at our hospital, the research involved 160 patients who were divided into two groups based on waiting times of 1 or 3 min postlidocaine application. Both objective and subjective discomfort levels were evaluated during the procedure. Objective discomfort assessment included the elevation of heart rate and systolic blood pressure. Subjective discomfort assessment included throat pain, nausea sensation, and abdominal fullness recorded from the patient’s questionnaire.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study indicated that a 3-min wait significantly reduced objective measures of discomfort, such as heart rate and blood pressure elevations, and subjective discomfort ratings, including throat pain and nausea. Furthermore, patients in the 3-min group expressed a lower willingness to undergo future sedated endoscopies, highlighting the importance of minimizing sedation-related risks in high-risk populations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The study findings suggest that extending the waiting period after lidocaine administration improves patient outcomes during EGD, advocating for a standardized protocol of 3 min to optimize analgesia and procedural comfort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov identifier: NCT06497296</p>\u0000 </section>\u0000 </div>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 6","pages":"1428-1434"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Stomach Cancer Burden in China: A Joinpoint and APC Analysis Based on GBD 2021","authors":"Xiangying Xie,&nbsp;Juan Su,&nbsp;Wei Wang,&nbsp;Huiling Wei,&nbsp;Qian Zhou,&nbsp;Ying Su,&nbsp;Lili Zhang","doi":"10.1111/jgh.16956","DOIUrl":"10.1111/jgh.16956","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aim</h3>\u0000 \u0000 <p>To study the corresponding strategies to control stomach cancer, a comprehensive assessment of the disease burden is required. Herein, we present long-term trends in the burden of stomach cancer in China over the past three decades, as well as its epidemiological features.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We characterized the burden of stomach cancer in China using the GBD 2021 methods and results, based on prevalence, incidence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) estimated using the DisMod-MR 2-1. We also used joinpoint and age–period–cohort (APC) analysis methods to interpret the epidemiological characteristics of stomach cancer, project the disease burden of stomach cancer in China over the next decade, and compare these trends with global prevalence patterns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The age-standardized incidence (ASIR) and mortality rates (ASMR) in both sexes changed from 48.03 (40.21, 56.69) to 29.05 (22.42, 36.2) and from 46.05 (38.88, 54.43) to 21.51 (16.66, 26.61) per 100 000 people in China from 1990 to 2021. The age-standardized DALY rate in China decreased from 1181.61 (978.38, 1390.89) per 100 000 people in 1990 to 501.26 (387.29, 627.98) per 100 000 people in 2021. The average annual percentage change (AAPC) in age-standardized incidence, prevalence, and mortality rates for stomach cancer in China were −1.61 (95% CI: −1.73, −1.48), −0.50 (95% CI: −0.67, −0.32), and −2.44 (95% CI: −2.62, −2.26). The effects of age, period, and cohort on mortality rates differed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In the next decade, China's ASIR and ASMR for stomach cancer will continue to decline. However, despite the decrease in incidence, the overall burden of stomach cancer in China will remain significantly higher than the global average. The burden of stomach cancer in China will be a major public health challenge, given the country's large population base and aging population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 6","pages":"1500-1514"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jgh.16956","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights on Weight Gain and MASLD Risk in Japanese Non-Obese Individuals","authors":"Miya Li,&nbsp;Qinlin Zhang,&nbsp;Ruhong Zhou","doi":"10.1111/jgh.16951","DOIUrl":"10.1111/jgh.16951","url":null,"abstract":"","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 5","pages":"1326-1327"},"PeriodicalIF":3.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Natural Language Processing Tool Improves Colonoscopy Auditing of Adenoma and Serrated Polyp Detection Rates","authors":"Melissa Chew,&nbsp;Catherine Yu,&nbsp;Leanne Stojevski,&nbsp;Paul Conilione,&nbsp;Anthony Gust,&nbsp;Mani Suleiman,&nbsp;Will Swansson,&nbsp;Bennett Anderson,&nbsp;Mayur Garg,&nbsp;Diana Lewis","doi":"10.1111/jgh.16933","DOIUrl":"10.1111/jgh.16933","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Study Aims</h3>\u0000 \u0000 <p>Determining adenoma detection rate (ADR) and serrated polyp detection rate (SDR) can be challenging as they usually involve manual matching of colonoscopy and histology reports. This study aimed to validate a Natural Language Processing (NLP) code that enables rapid and efficient data extraction to calculate ADR and SDR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>A NLP code was developed to automatically extract colonoscopy quality indicators from colonoscopy and histology reports at a tertiary health service. These reports were manually reviewed to verify the concordance of ADR and SDR between the two methods. This process was applied in the initial training phase, repeated following modification of the code, and again with a validation cohort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Included in the training and test phases were 5911 colonoscopies, with 2022 in the validation phase. The NLP code extracted patient names with 99.9% concordance and had a 98.9% accuracy in ADR and SDR in the training phase. Search terms were subsequently modified to take into consideration spelling variations and overlapping terminologies. Using data from the same cohort, accuracy of the NLP improved to 100%, excluding four colonoscopies that had missing histology reports in the test phase. Using a validated cohort, NLP had a 99.9% accuracy in ADR and SDR. The total time taken for auditing using NLP in the validation phase was less than 1 h.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>An automatic NLP code had an accuracy of almost 100% in determining ADR and SDR in a tertiary colonoscopy service. Wider adoption of NLP enables significant improvements in colonoscopy audits that is accurate and time efficient.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 5","pages":"1230-1237"},"PeriodicalIF":3.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Endoscopy in Clinical Management of Intraductal Papillary Mucinous Neoplasms","authors":"Tsuyoshi Hamada,&nbsp;Hiroki Oyama,&nbsp;Naminatsu Takahara,&nbsp;Yousuke Nakai,&nbsp;Mitsuhiro Fujishiro","doi":"10.1111/jgh.16938","DOIUrl":"10.1111/jgh.16938","url":null,"abstract":"<p>Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a well-recognized precursor of pancreatic carcinoma. Along with cross-sectional abdominal imaging tests, endoscopic examinations remain the cornerstone in the diagnosis of pancreatic cysts, early detection of IPMN-derived carcinomas, and risk stratification of patients with IPMNs for subsequent surveillance strategies. In particular, endoscopic ultrasound (EUS) facilitates the optimal patient management by providing high-resolution morphological information, and the contrast-enhanced harmonic mode may further enhance diagnostic accuracy. EUS-guided fine-needle aspiration for solid mass and/or cyst fluid is considered for pathological and molecular examinations for the diagnosis of pancreatic cysts and malignancy. Emerging evidence suggests the usefulness of through-the-needle biopsy and confocal laser microendoscopy in this setting. In addition to the undoubtful diagnostic utility, recent studies have demonstrated the potential effect of endoscopic interventions (i.e., ablation) on the control of IPMNs. Despite the increasing role of endoscopy in the clinical management of IPMNs, there remains a gap in our understanding of how to utilize endoscopy in the personalized care for patients with IPMNs (e.g., the optimal interval of EUS) and the prevention of deaths due to pancreatic carcinomas developing concomitantly with IPMNs.</p><p>This review summarizes the current evidence on the role of endoscopy in both the diagnostic and therapeutic landscapes of clinical management of IPMNs and identifies key clinical unmet needs that should be addressed in future research. Combined with emerging technologies (e.g., artificial intelligence and high-throughput molecular profiling), endoscopy would offer more effective and tailored management strategies for patients with IPMNs.</p>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 5","pages":"1045-1058"},"PeriodicalIF":3.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jgh.16938","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preferred Reporting Items for Microbiotherapy (PRIM) Guidelines Across Medical Disciplines: An International Delphi Consensus","authors":"Faming Zhang,&nbsp;Michael A. Kamm,&nbsp;Xia Wu,&nbsp;Dina Kao,&nbsp;Thomas J. Borody,&nbsp;Lea Ann Chen,&nbsp;Xingxiang He,&nbsp;Monika Fischer,&nbsp;Sunny H. Wong,&nbsp;Siew C. Ng,&nbsp;Bota Cui,&nbsp;Francis K-L Chan,&nbsp;Yongzhan Nie,&nbsp;Ajit Sood,&nbsp;Jingnan Li,&nbsp;Yang Sun,&nbsp;Ishikawa Dai,&nbsp;Qiyi Chen,&nbsp;Muhan Lv,&nbsp;Zulun Zhang,&nbsp;Gianluca Ianiro,&nbsp;Yunsheng Yang,&nbsp;Colleen R. Kelly","doi":"10.1111/jgh.16947","DOIUrl":"10.1111/jgh.16947","url":null,"abstract":"<p>Microbiotherapy has opened new avenues for managing dysbiosis-related diseases. However, many studies did not cover all the necessary reporting items for microbiotherapy making the interpretation of results, safety assessment, technology extension, and even the transparency of legitimacy difficult. This project consisted of 2 phases. First, we proposed an initial preferred reporting items for microbiotherapy (PRIM) checklist and applied it to oncology studies from 2011 to 2023 according to Meta-Analyses guideline. Only 39.3% (<i>n</i> = 64) of these studies (<i>n</i> = 163) met all PRIM checklist items. The culture-based microbiotherapy (CMT) studies had higher score than non-culture-based (NMT) ones (<i>p</i> = 0.018). In the second phase, the expert panel consisting of 22 specialists from eight countries across Asia, Australia, Europe, and North America refined and finalized the PRIM guidelines (named as PRIM 2024) through Delphi consensus. The PRIM 2024 guidelines conclude 10 statements and 18 points on diagnosis, delivery route, source, classification, preparation, dosage, state, concomitant treatment, efficacy, and safety. The panel defined less than 80% of all PRIM points (14 points) as low-quality reports. These guidelines are recommended for reporting on microbiotherapy in clinical studies and reports on compassionate use, including but not limited to fecal microbiota transplantation, phage therapy, probiotics, and synbiotics. These consistent and transparent reporting items can help researchers and practitioners better evaluate, compare, implement research findings in microbiotherapy.</p>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 6","pages":"1364-1373"},"PeriodicalIF":3.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jgh.16947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to Editor: Addressing Methodological and Interpretative Gaps in the Study on Bowel Preparation and Gut Microbiotad","authors":"Brijesh Sathian,&nbsp;Hanadi Al Hamad,&nbsp;Javed Iqbal","doi":"10.1111/jgh.16957","DOIUrl":"10.1111/jgh.16957","url":null,"abstract":"","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 5","pages":"1330-1331"},"PeriodicalIF":3.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Long-Term Efficacy of Peroral Endoscopic Myotomy in Pediatric Achalasia","authors":"Yuto Shimamura,&nbsp;Hiroki Sato,&nbsp;Ryusuke Yagi,&nbsp;Hirofumi Abe,&nbsp;Hironari Shiwaku,&nbsp;Junya Shiota,&nbsp;Chiaki Sato,&nbsp;Kenta Hamada,&nbsp;Masaki Ominami,&nbsp;Yoshitaka Hata,&nbsp;Hisashi Fukuda,&nbsp;Ryo Ogawa,&nbsp;Jun Nakamura,&nbsp;Tetsuya Tatsuta,&nbsp;Yuichiro Ikebuchi,&nbsp;Haruhiro Inoue","doi":"10.1111/jgh.16945","DOIUrl":"10.1111/jgh.16945","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Aims</h3>\u0000 \u0000 <p>Pediatric achalasia and peroral endoscopic myotomy (POEM) are not well investigated. This study aimed to examine the clinical characteristics of pediatric achalasia and evaluate the long-term outcomes of POEM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a multicenter study across 14 high-volume centers, comparing the clinical characteristics of children (aged &lt; 18 years) diagnosed with achalasia to those of adults (aged &lt; 65 years). The POEM procedures and outcomes were also compared between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 3421 patients with achalasia, 50 (1.5%) were children. Compared with adults, children had a shorter period to diagnosis (1.0 vs. 3.4 years; <i>p</i> &lt; 0.001) and were more likely to be severely underweight (body mass index: 17.8 vs. 20.9 kg/m²; <i>p</i> &lt; 0.001). However, children exhibited less esophageal dilation (46.0% vs. 64.1%; <i>p</i> = 0.013) and higher lower esophageal sphincter pressure (37.3 vs. 29.9 mmHg; <i>p</i> = 0.002). Notably, a significant failure to thrive was not observed in the pediatric group. The POEM procedure time was shorter for children compared to adults (58.0 vs. 83.0 min; <i>p</i> &lt; 0.001). Clinical success rates were not significant between the two groups. Over the 5-year follow-up period, children had a lower incidence of reflux esophagitis following POEM compared to adults (11.0% vs. 26.4%; <i>p</i> = 0.013).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Pediatric achalasia is rare and typically presents with early-stage manometric and esophagogastric features, along with severe systemic symptoms requiring an early diagnosis. POEM is a durable and effective treatment for pediatric achalasia, offering advantages such as shorter procedural times and a lower incidence of postprocedure reflux compared to adults.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 6","pages":"1446-1453"},"PeriodicalIF":3.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Telemedicine Enough to Eradicate Hepatitis C Virus by 2030?","authors":"Amina Hassan","doi":"10.1111/jgh.16952","DOIUrl":"10.1111/jgh.16952","url":null,"abstract":"","PeriodicalId":15877,"journal":{"name":"Journal of Gastroenterology and Hepatology","volume":"40 5","pages":"1328-1329"},"PeriodicalIF":3.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}