Second Examination of the Right Colon Using Narrow-Band Imaging Increases Adenoma Detection Rates in the Right Colon: A Multicenter, Randomized Controlled Trial.

IF 3.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Journal of Gastroenterology and Hepatology Pub Date : 2025-04-14 DOI:10.1111/jgh.16964

Shin Hee Kim, One Zoong Kim, In Kyung Yoo, Jae Yong Park, Young Joo Yang, Jin Hwa Park, Sang Pyo Lee, Jae Gon Lee

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引用次数: 0

Abstract

Background/aims: Repeat examination of the right colon increases adenoma detection rates (ADRs) in the right colon. This study aimed to investigate whether a second examination of the right colon using narrow-band imaging (NBI) increases ADRs in the right colon compared with repeat examinations using white light imaging (WLI).

Methods: Consecutive patients with routine indications for colonoscopy were enrolled and randomly assigned to two groups. The control arm underwent two repeat forward examinations of the right colon using WLI only (repeat-WLI group), and the intervention arm underwent the first examination of the right colon using WLI and the second examination using NBI (WLI-NBI group). Lesions detected during the first and second examinations in each group were analyzed. The primary outcome was ADR in the right colon.

Results: A total of 476 colonoscopies were analyzed, including 240 and 236 in the repeat-WLI and WLI-NBI groups, respectively. The overall ADR in the right colon was significantly higher in the WLI-NBI group than that in the repeat-WLI group (27.1% vs. 17.9%; p = 0.022). The number of adenomas per colonoscopy in the right colon was also significantly higher in the WLI-NBI group than in the repeat-WLI group (mean number of adenomas, 0.36 vs. 0.24; p = 0.042). However, there were no significant differences in the detection rates of advanced adenomas and sessile serrated lesions between the WLI-NBI and repeat-WLI groups (advanced adenoma, 4.7% vs. 2.9%; sessile serrated lesion, 2.5% vs. 3.3%).

Conclusion: A second forward examination of the right colon using NBI increased ADRs in the right colon.

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右结肠二次检查窄带成像增加右结肠腺瘤检出率：一项多中心随机对照试验

背景/目的：重复检查右结肠可增加右结肠腺瘤的检出率。本研究旨在探讨与使用白光成像（WLI）重复检查相比，使用窄带成像（NBI）对右结肠进行第二次检查是否会增加右结肠的不良反应。方法：连续纳入符合常规结肠镜检查指征的患者，随机分为两组。对照组仅使用WLI对右结肠进行两次重复正向检查（repeat-WLI组），干预组使用WLI对右结肠进行第一次检查，使用NBI进行第二次检查（WLI-NBI组）。分析各组第一次和第二次检查中发现的病变。主要结果是右结肠的不良反应。结果：共分析476例结肠镜检查，其中repeat-WLI组240例，WLI-NBI组236例。WLI-NBI组右结肠总不良反应显著高于重复- wli组(27.1% vs. 17.9%；p = 0.022)。WLI-NBI组每次结肠镜检查右结肠腺瘤数量也显著高于重复wli组(平均腺瘤数量，0.36 vs 0.24；p = 0.042)。然而，在WLI-NBI组和重复wli组之间，晚期腺瘤和无底锯齿状病变的检出率没有显著差异(晚期腺瘤，4.7% vs. 2.9%；无柄锯齿状病变（2.5% vs. 3.3%）。结论：使用NBI对右结肠进行第二次前诊会增加右结肠的不良反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Gastroenterology and Hepatology 医学-胃肠肝病学

CiteScore

7.90

自引率

2.40%

发文量

326

审稿时长

2.3 months

期刊介绍： Journal of Gastroenterology and Hepatology is produced 12 times per year and publishes peer-reviewed original papers, reviews and editorials concerned with clinical practice and research in the fields of hepatology, gastroenterology and endoscopy. Papers cover the medical, radiological, pathological, biochemical, physiological and historical aspects of the subject areas. All submitted papers are reviewed by at least two referees expert in the field of the submitted paper.