Journal of Health Science最新文献

{"title":"HUBUNGAN INTERAKSI SOSIAL TERHADAP TINGKAT KESEPIANDANKUALITAS HIDUP PADA LANSIA DI UPTD GRIYA WERDHA JAMBANGAN SURABAYA","authors":"Astrida Budiarti","doi":"10.33086/jhs.v13i2.1217","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1217","url":null,"abstract":"ABSTRAK \u0000Masalah pada lansia yaitu terjadi penurunan interaksi sosial karena faktor kesehatan maupun kehilangan pasangan dan kunjungan keluarga yang jarang sehingga menimbulkan perasaan kesepian dan penurunan kualitas hidup pada lansia. Penelitian ini bertujuan untuk mengetahui hubungan interaksi sosial terhadap tingkat kesepian dan kualitas hidup lansia di UPTD Griya Werdha Jambangan Surabaya. \u0000Desain penelitian ini observasional analitik dengan pendekatan cross sectional. Sampel menggunakan Simple Random Sampling sebanyak 77 lansia di UPTD Griya Werdha Jambangan Surabaya. Variabel independen dalam penelitian ini adalah interaksi sosial yang diukur dengan instrumen kuesioner terstruktur. Variabel dependen dalam penelitian ini adalah tingkat kesepian yang diukur dengan instrumen kuesioner UCLA Loneliness Version 3 dan kualitas hidup yang diukur dengan instrumen kuesionerWHOQOL-BREF. Analisis data menggunakan uji Spearman rho ρ=0,05.  \u0000Hasil penelitian ini menunjukkan bahwa terdapat hubungan interaksi sosial terhadap tingkat kesepian lansia dengan ρ = 0.001 (ρ≤0.05) dan terdapat hubungan interaksi sosial terhadap kualitas hidup lansia dengan ρ = 0.001 (ρ≤0.05). \u0000Implikasi dari penelitian ini yaitu interaksi sosial berperan penting dalam mengurangi tingkat kesepian dan meningkatkan kualitas hidup lansia, sehingga perlu adanya pendampingan dalam kegiatan kelompok kecil dan kunjungan keluarga yang rutin. \u0000Kata Kunci :Lansia, Interaksi Sosial. Kesepian, Kualitas Hidup \u0000  \u0000ABSTRACT \u0000The problem in the elderly is that there is a decrease in social interaction due to health factors and loss of spouses and rare family visits, giving rise to feelings of loneliness and decreased quality of life in the elderly. This study aims to determine the relationship of social interactions to the level of loneliness and quality of life of the elderly in the UPTD Griya Werdha Jambangan Surabaya. \u0000The study design was observational analytic with a cross sectional approach. The sample used Simple Random Sampling as many as 77 elderly at the Griya Werdha UPTD Surabaya. The independent variable in this study is social interaction measured by a structured questionnaire instrument. The dependent variable in this study was the level of loneliness measured by the UCLA Loneliness Version 3 questionnaire instrument and quality of life as measured by the WHOQOL-BREF questionnaire. Data analysis using the Spearman rho test ρ = 0.05. \u0000The results of this study indicate that there is a relationship of social interaction to the loneliness level of the elderly with ρ = 0.001 (ρ≤0.05) and there is a relationship of social interaction with the quality of life of the elderly with ρ = 0.001 (ρ≤0.05). \u0000The implication of this study is that social interaction plays an important role in reducing the level of loneliness and improving the quality of life of the elderly, so that there is a need for assistance in small group activities and regular family visits. \u0000Keywords: Elderly, Social interac","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"170 1","pages":"124-133"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76459682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinan Quality of life Pada Pasien TB Paru di Kota Surabaya","authors":"Eppy Setiyowati, Umi Hanik, diba adiba, Elok Mazida Mazida, Ratna Wahyuni, Feri Agus Andriawan, S. Hardianti","doi":"10.33086/jhs.v13i2.1306","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1306","url":null,"abstract":"Tuberkulosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which can attack various organs, especially the lungs. The infectius disease untreated or treatment is not complete can causing complications dangerous until death. TB estimated to have existed in the world since 5000 BC, but advances in the discovery and control of new TB disease occurred in 2 of the last century. This study aimed determinant of quality of life in patients with pulmonary TB in Surabaya \u0000Type a descriptive research with survey approach on three large health centers with a total population sample of 150 respondents. The variable determinant of quality of life includes the respondents perception of the disease, health care search is done, the meaning of life for the respondents, satisfaction with family and health care. Data were collected through questionnaires, through purpusive sampling techniques, then performed the frequency distribution and crostabulasi. \u0000The results showed that the respondents' perceptions of the disease is mostly 78.4% said the illness as a result of the process of transmission of TB bacteria mycobaterium, the search for health services 95.7% went to the clinic, the meaning of life for themselves 78.6% said there was no hope for healed, satisfaction with family 67.5% are satisfied with the spirit given by family members and satisfaction of health workers say 85.3% are satisfied with the services provided by a health worker. \u0000The conclusion shows that detrminan quality of life in patients with pulmonary tuberculosis have searched for health services to the health service, satisfied with the health workers, but there is no hope of life to recover. Suggestions for further research to dig deeper into the life expectancy of the respondents","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"84 1","pages":"116-123"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77251320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan Kejadian Ko-Infeksi Soil-Transmitted Helminths pada Pasien Tuberkulosis dengan Jumlah Eosinofil di Kecamatan Kalisat Kabupaten Jember","authors":"Widhiasari Normaningtyas, M. Shodikin, Angga Mardro Raharjo, Dini Agustina, D. Mufida, Yunita Armiyanti","doi":"10.33086/jhs.v13i2.1462","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1462","url":null,"abstract":"Abstrak: Tuberkulosis (TB) menjadi masalah kesehatan utama baik lingkup global maupun nasional. Tuberkulosis menyebabkan status gizi kurang baik. Status gizi yang kurang baik dapat disebabkan oleh infeksi kronis, salah satunya infeksi cacing usus terutama Soil-Transmitted Helminths (STH). Ko-infeksi STH pada pasien TB selain mempengaruhi status gizi, juga akan mempengaruhi respon imun pasien. Respon imun pada pasien ko-infeksi STH akan menghambat respon imun Th 1 dalam melawan TB serta akan didapatkan peningkatan eosinofil (eosinofilia). Tujuan utama dalam penelitian ini adalah untuk mengetahui jumlah eosinofil pada pasien tuberkulosis terhadap ko-infeksi STH di Kecamatan Kalisat, Kabupaten Jember. Jenis penelitian ini adalah penelitian observasional dengan desain analitik cross sectional. Populasi yang digunakan adalah pasien TB di Kecamatan Kalisat dalam periode waktu September – Desember 2019. Data yang digunakan dalam penelitian ini adalah data primer berupa hasil pemeriksaan darah dengan metode hitung jenis dan hasil pemeriksaan feses menggunakan metode sedimentasi dan floatasi. Analisis data dilakukan menggunakan uji Fisher. Hasil penelitian menunjukkan bahwa kejadian koinfeksi STH pada pasien TB di Kecamatan Kalisat Kabupaten Jember sebesar 3,6% dan disebabkan oleh Hookworm. Hasil uji Fisher menunjukkan tidak ada hubungan yang signifikan antara jumlah eosinofil dengan kejadian koinfeksi STH pada pasien TB di Kecamatan Kalisat Kabupaten Jember dengan nilai p-value 1,000. \u0000Kata kunci: Tuberkulosis, Soil-Transmitted Helminths, Eosinofilia","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"1 1","pages":"180-193"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76124900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI PERILAKU IBU HAMIL DALAM MELAKUKAN DETEKSI DINI RISIKO TINGGI KEHAMILAN","authors":"Ika Mardiyanti, Yasi Anggasari","doi":"10.33086/jhs.v13i2.1473","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1473","url":null,"abstract":"Setiap kehamilan mempunyai kemungkinan terjadi komplikasi dapat membahayakan ibu atau bayi, baik pada kehamilan risiko rendah, maupun risiko tinggi. Salah satu upaya untuk mencegah kehamilan risiko tinggi ibu hamil adalah dengan melakukan deteksi dini risiko tinggi pada kehamilan. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa yang berhubungan dengan perilaku ibu hamil dalam melakukan deteksi dini risiko tinggi kehamilan di PMB Ika Mardiyanti Desa Jedong Cangkring Prambon Sidoarjo. \u0000Penelitian ini menggunakan rancangan kuantitatif dengan desain penelitian cross sectional. Sampel dalam penelitian ini diambil dengan tehnik simple random sampling. Metode pengumpulan data menggunakan data primer, dengan melakukan anamnesa terhadap perilaku ibu hamil dalam deteksi dini kehamilan risiko tinggi. Analisis data menggunakan uji statistik Regresi linier. \u0000Hasil penelitian menunjukkan (56,7%) responden berusia risiko rendah (20-35 tahun), (83,3%) berpendidikan menengah, (80%) berpendapatan cukup, (60%) berpengalaman, (63,3%) berpengetahuan cukup, (40%) tidak pernah terpapar media, (60%) perilaku tidak tercapai. Analisis statistik dengan regresi linier didapatkan ρ>0,05 yang berarti faktor usia, pendidikan, pendapatan, pengalaman, pengetahuan, paparan media tidak berpengaruh terhadap perilaku. \u0000Kesimpulan Tidak ada faktor yang berpengaruh secara signifikan terhadap perilaku ibu hamil dalam melakukan deteksi dini risiko tinggi kehamilan di PMB Ika Mardiyanti Diharapkan bidan meningkatkan KIE tentang deteksi dini kehamilan risiko tinggi sehingga mampu menurunkan angka kejadian komplikasi kehamilan dan persalinan.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"90 1","pages":"134-143"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83915059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENGARUH METODE EMOTIONAL DEMONSTRATION TERHADAP PENINGKATAN CAKUPAN PENIMBANGAN BALITA DI POSYANDU","authors":"Iit Ermawati, Wahida Yuliana, Bawonul Hakim","doi":"10.33086/jhs.v13i2.1332","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1332","url":null,"abstract":"Abstract:Posyandu (Integrated Service Post) is one form of Community-based Health Efforts (UKBM) carried out by, from and with the community, to empower and provide facilities to the community to obtain health services for mothers, infants and toddlers. In Posyandu activities there are indicators that determine the success of activities, one of which is the coverage of weighing toddlers as a form of community presence. The problem of coverage of underfive weighing in Indonesia was found to be the difference between the number of toddlers and toddlers weighed, namely 12,817,382 toddlers. This data was obtained from info Datin (Health Data and Information Center of the Republic of Indonesia) in 2014. In East Java Province an estimated number of toddlers was 2,985,934, and the number of toddlers weighed 1,588,030 so that there were still 50% that were not included in the coverage of underfive weighing. The results of the preliminary study of the number of children under five were present 45% irregularly in attendance each month. Even though nutrition monitoring with weight weighing must be done every month. While the monthly attendance limit for 1 year is 8 x. This presence needs cadre participation as part of the community itself. This study aims to determine whether there is the influence of the emotional demonstration method on increasing the coverage of underfive weighing. This study uses a one shot case study pre-experimental research design. The population is all under-five mothers in Sidodadi Village, which number 333 people. The sampling technique used is simple random sampling. Test Statistics used to see the relationship between variables bound to independent variables. The analysis used was the chi-square statistical test of significance level of 95% (alpha 0.05) using SPSS. The results of 333 respondents, mothers of children under five who came to the Posyandu village of Sidodadi, Probolinggo Regency in December 2018 - June 2019 before the emodemo were attended by 153 mothers and when there was an emodemo activity the number of attendees increased to 285 mothers who attended Keposyandu .. Test results statistic is pvalue <0.05. The conclusion of this study is that there is the influence of the emotional demonstration method on increasing the coverage of underfive weighing in the Posyandu village of Sidodadi.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"54 1","pages":"165-171"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73516843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALYSIS OF ECONOMIC STATUS WITH SCIENTIFIC CONTRACEPTION SELECTIONS IN BPM MOGITA TLANAKAN PAMEKASAN","authors":"Nova Purma Hardini","doi":"10.33086/jhs.v13i2.1177","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1177","url":null,"abstract":"Abstract \u0000   In the effort of decreasing the rate of population, government, implement the family plan program in order to make the quality family in year 2018. Many use injection hormonal contraception since it has the effective work, practice, cheap and safe relatively. In selecting the contraception effected by several factors, for instance age, education, work, parity, knowledge, resident, economic status, decision in the household, and culture. Economic status can influence someone in choosing the contraception particularly injection contraceptive. \u0000   The purpose of this search is to know the relationship between economic status and injection contraception selecting. \u0000   Research design is using analytic with cross sectional. This research was conducted at BPM Mogita Tlanakan Pamekasan starting from July 01, 2018  to August 31, 20018. Population is all the family plan acceptor and sample taking was done by probability sampling with sampling random simple with sample size is 49 respondents. \u0000   The research result denoted that from 49 respondents, 10 of then have the high economic statuses who are wearing injection are 3 persons and not are 7 persons. 14 respondents have the mid-economic status are wearing injection us 11 person and not is 3 persons and 25 respondent have the low economic status are wearing injection is 23 person and are not is 2 persons. \u0000   By using the Mann Whitney statistic with level of significant is 0,05 was obtained count  ≤  thus H0 was rejected, meaning that there is difference economic status with selecting the injection contraception and non-injection at di BPM Mogita Tlanakan Pamekasan. \u0000   Of the result research can be drawn the conclusion that economic status constitutes factor that influence the injection family plan selecting. In which they have the low economic status tend to choose the injection family plan than the high one. However, it needs the further research with seeing and enter the other factors that influence in contraception selecting. \u0000Keywords: economic status, injection contraception selecting.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"80 1","pages":"150-156"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73982781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PENGARUH SOSIALISASI KESIAPSIAGAAN BENCANA MELALUI METODE SIMULASI TERHADAP PENINGKATAN KETRAMPILAN DALAM MENGAHADAPI BENCANA PADA MAHASISWA SIAGA BENCANA (MAGANA) UNIVERSITAS NAHDLATUL ULAMA SURABAYA","authors":"Priyo Mukti Pribadi Winoto, Chilyatiz Zahroh","doi":"10.33086/jhs.v13i2.1474","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1474","url":null,"abstract":"Kesiapsiagaan bencana merupakan serangkaian kegiatan yang dilakukan untuk mengantisipasi bencana melalui pengorganisasian serta melalui langkah yang tepat guna dan berdaya guna. Namun masih banyak diantara kita belum siap apa yang harus dilakukan jika terjadi bencana. Penelitian ini bertujuan untuk mengetahui pengaruh sosialisasi terhadap ketrampilan mahasiswa untuk meningkatkan ketrampilan dalam mengahadapi bencana. \u0000Penelitian ini menggunakan rancangan kuantitatif dengan desain penelitian cross sectional. Sampel dalam penelitian ini diambil dengan tehnik simple random sampling. Metode pengumpulan data menggunakan data primer, dengan memberikan sosialisasi dalam bentuk penyuluhan dan demonstrasi, selanjutnya melihat ketrampilan remaja dengan mengggunakan ceklist. Analisis data menggunakan uji statistik Willcoxon. \u0000Hasil penelitian menunjukkan (65%) responden berusia 16-18 tahun, (60%) tidak pernah mendapatkan informasi tentang kebencanaan.Analisis statistik dengan Willcoxon didapatkan ρ=0,003<α=0,05 artinya ada pengaruh simulasi kebencanaan terhadap ketrampilan, dan dari hasil Mann Withney didapatkan ρ=0,007<α=0,05 artinya ada beda ketrampilan antara kelompok intervensi dan kelompok kontrol. \u0000Kesimpulan ada pengaruh pemberian simulasi terhadap ketrampilan pada mahasiswa siaga bencana. Diharapkan perawat mampu meningkatkan pemahaman dan ketrampilan masyarakat tentang penatalaksanaan kegawatdaruratan di komunitas.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"92 1","pages":"157-164"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87118584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MELATIH KEMANDIRIAN ANAK DOWN SYNDROME DENGAN MOTOTRAIN","authors":"Machmudah Machmudah, M. Shodiq","doi":"10.33086/jhs.v13i2.1536","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1536","url":null,"abstract":"Practicing toilet training from parents to children is quite challenging especially if the child has special needs. For children with Down syndrome, the habit of toilet training takes longer than normal children who can be completed before school age. The purpose of this study was to determine the effectiveness of Mototrain on maternal knowledge and independence of toilet training in children with Down syndrome. Mototrain is an acronym for Module of Toilet Training. \u0000The population and sample in this study were parents and students with Down syndrome who had not yet completed their toilet training independence, namely 31 students spread across Grade 1, Grade 2, Grade 3, Grade 4 and Grade 5 in SD C Alpha Kumara. The research design was \"Quasi experimental pre-post test with control group\", with a purposive sampling technique of 16 mothers and children in the intervention group and 15 mothers and children in the control group. The results showed an increase in maternal knowledge about toilet training and the independence of toilet training in children who used enough after being given psychoeducation and habituation in accordance with MOTOTRAIN (p-value <0.05).","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"32 1","pages":"215-223"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85089515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PERAN PROTEIN HEMAGLUTININ PILI Streptococcus pneumoniae 54 kDa SEBAGAI ADHESIN","authors":"D. Mufida, Adellia Fira Fa'idha, Zahrah Febianti","doi":"10.33086/jhs.v13i2.1442","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1442","url":null,"abstract":"Received: January, 20, 2020 Revised: May, 6, 2020 Available online: August, 2020 Introduction: Pili has an adhesin that plays a role in the adhesion process in order to infect the host cell. Research shown that the 54 kDa S. pneumoniae pili protein is a hemagglutinin. This study was to examine whether the 54 kDa of S. pneumoniae pili protein also act as an adhesin. Method: S. pneumoniae was isolated using a pili cutter. The protein molecular weight was analyzed using SDS-PAGE. Protein with a molecular weight of 54 kDa was isolated to produce protein solution. Adhesion test was carried out on a protein solution with multilevel concentrations to determine the adhesion index. Result: Pearson correlation test obtained p-value of 0.036 and the correlation coefficient R = -0.840, these results indicate that the two variables have a significant negative relationship. Regression analysis showed R2 0,997, mean that 99.7% of the concentration of protein S. pneumoniae 54 kDa influenced the adhesion index. Conclusion: Therefore, it can be concluded that the hemagglutinin protein S. pneumoniae 54 kDa is an adhesin protein. A B S T R A K Latar Belakang: Pili memiliki protein adhesin yang berperan dalam proses adhesi untuk menginfeksi sel hospes. Penelitian sebelumnya menunjukkan bahwa protein pili S. pneumoniae 54 kDa merupakan protein hemaglutinin. Tujuan penelitian ini adalah menguji peran protein hemaglutinin pili S. pneumoniae 54 kDa sebagai adhesin. Metode: Pili S. pneumoniae diisolasi menggunakan alat pili cutter. Hasil potongan pili dilakukan SDS-PAGE untuk mengidentifikasi berat molekul proteinnya. Protein berat molekul 54 kDa diisolasi sehingga menghasilkan larutan protein. Larutan protein diuji adhesi dengan konsentrasi bertingkat untuk mengetahui indeks adhesi. Hasil: Uji korelasi Pearson diperoleh nilai p-value 0,036 (p < 0,05) dan koefisien korelasi R= -0,840. Hasil ini menunjukkan bahwa kedua variabel memiliki hubungan yang signifikan, sangat kuat dengan arah hubungan negatif. Analisis regresi didapatkan R2 0,997, artinya 99,7 % konsentrasi protein pili 54 kDa S. pneumoniae mempengaruhi indeks adhesi. Kesimpulan: protein hemaglutinin pili 54 kDa S. pneumoniae merupakan protein adhesin","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"91 1","pages":"194-203"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80586345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analisis Parameter Leukosit dalam Diagnosis Awal Sepsis Neonatorum Awitan Dini di RSIA Ananda Makassar","authors":"Gita Yustika","doi":"10.33086/jhs.v13i2.1475","DOIUrl":"https://doi.org/10.33086/jhs.v13i2.1475","url":null,"abstract":"Sepsis pada bayi baru lahir sampai saat ini masih menjadi salah satu masalah yang menyebabkan tingginya angka morbiditas dan mortalitas pada bayi baru lahir di Indonesia. Standar emas dari sepsis neonatrum adalah kultur darah, namun membutuhkan waktu yang lama. Parameter leukosit pada penelitian ini memiliki keunggulan yaitu pemeriksaan dapat lebih cepat diperoleh hasilnya. Penelitian ini bertujuan untuk menganalisis parameter leukosit dalam diagnosis awal sepsis neonatorum awitan dini (SNAD) di RSIA Ananda Makassar. Penelitian ini merupakan penelitian cross-sectional menggunakan data sekunder berupa rekam medis bayi yang dicurigai SNAD di RSIA Ananda Makassar Tahun 2019. Jumlah keseluruhan sampel sebesar 96 neonatus, 77 neonatus (80%) SNAD, dan 19 neonatus tidak SNAD (20%). Parameter leukosit yang digunakan pada penelitian ini yaitu jumlah leukosit total, jumlah neutrofil absolut, dan jumlah limfosit absolut. Hasil penelitian yaitu 76 neonatus (98.70%) mengalami leukositosis (p-value = 0.000), 73 neonatus (94.81%) mengalami neutrofilia (p-value = 0.000), dan 51 neonatus (66.23%) yang mengalami limfositosis (p-value = 0.000), dan jumlah limfosit absolut p-value = 0.000. Sehingga dapat disimpulkan, terdapat hubungan signifikan antara parameter leukosit dengan sepsis neonatorum awitan dini.","PeriodicalId":15873,"journal":{"name":"Journal of Health Science","volume":"25 1","pages":"204-214"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90322177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}