Journal of gynecology obstetrics and human reproduction最新文献

{"title":"Fertility preservation for transgender, non-binary, and gender-expansive individuals in France: A comprehensive assessment of healthcare services and practices","authors":"Maxime Chaillot ,&nbsp;Sophie Brouillet ,&nbsp;Noémie Ranisavljevic ,&nbsp;Bérengère Ducrocq ,&nbsp;Anne Mayeur ,&nbsp;Brigitte Keriven-Dessomme ,&nbsp;Thomas Freour ,&nbsp;Sylvie Morel ,&nbsp;Arnaud Reignier","doi":"10.1016/j.jogoh.2025.103002","DOIUrl":"10.1016/j.jogoh.2025.103002","url":null,"abstract":"<div><h3>Introduction</h3><div>Fertility preservation (FP) consultations are recommended before treatments that may affect fertility, including gender-affirming hormone therapy (GAHT). While some FP centers in France assist individuals undergoing gender transition, many transgender, non-binary, and gender-expansive individuals still choose not to pursue gamete cryopreservation. This study provides an overview of access to FP for transgender individuals in France in 2021.</div></div><div><h3>Materials and methods</h3><div>This descriptive observational study includes 47 French centers authorized to conduct FP activities. A total of 85.1 % (40/47) of these centers responded to an online questionnaire conducted between September 2022 and March 2023. The questionnaire addressed the activities of the centers in 2021, waiting times, methods of care for transgender, non-binary, and gender-expansive individuals, and training provided to healthcare professionals.</div></div><div><h3>Results and discussion</h3><div>In 2021, 29 centers reported performing FP cycles for transgender, non-binary, and gender-expansive individuals, with some showing specialized expertise. Significant differences were noted between oocyte and sperm cryopreservation. Waiting times for sperm freezing were acceptable, but oocyte freezing faced longer delays. Some centers provided professional training and communication activities to promote services. The findings highlight the need for improved regional coverage, shorter waiting times, and better communication to ensure equitable access to fertility care for all.</div></div><div><h3>Conclusion</h3><div>This study reveals disparities in access to and quality of FP services for transgender, non-binary, and gender-expansive individuals in France. Further evaluations are needed to understand the disparities between centers and, where possible, include all centers offering FP services in France.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 103002"},"PeriodicalIF":1.6,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What are the risk factors for severe neonatal acidosis in labor at term? A single-center retrospective case-control study","authors":"A. Sauvage ,&nbsp;L. Descourvieres ,&nbsp;N. Ramdane ,&nbsp;D. Subtil ,&nbsp;L. Ghesquiere ,&nbsp;C. Garabedian","doi":"10.1016/j.jogoh.2025.103001","DOIUrl":"10.1016/j.jogoh.2025.103001","url":null,"abstract":"<div><h3>Objective</h3><div>The aim was to determine the risk factors associated with severe acidosis during labor in newborns at term.</div></div><div><h3>Methods</h3><div>This was a retrospective monocentric case-control study, from January 2018 to December 2020. Cases included were all births with pH &lt;7.0 at birth, single pregnancy, &gt;37 weeks, without severe fetal malformation, and with an attempted vaginal delivery. For each included case, two controls were selected. These were the two deliveries immediately preceding the case, with pH &gt;7.0 and no exclusion criteria. The two groups were compared as pairs, followed by a multivariate analysis of factors associated with the occurrence of severe acidosis.</div></div><div><h3>Results</h3><div>Eighty-seven cases of severe acidosis were compared with 174 controls. After multivariate analysis, factors associated with the occurrence of acidosis were induction (odds ratio (OR) 2.41, confidence interval (CI) 95 %, 1.10–5.26), meconium fluid during labor (OR 4.38, CI 95 %, 1.14–16.78), the presence of uterine hyperstimulation (OR 3.15, CI 95 %, 1.45–6.83), and the occurrence of a sentinel event (shoulder dystocia, cord prolaps, uterine rupture) with OR 11.74, CI 95 %, 2.93–46.97. Conversely, increasing gestational age at delivery in weeks was found to be a protective factor (OR 0.33, CI 95 %, 0.24–0.46).</div></div><div><h3>Conclusion</h3><div>Several factors have been identified as being associated with the occurrence of acidosis. Their presence should alert the on-call team. The main factor, however, was the occurrence of a sentinel event, which is difficult to predict.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 103001"},"PeriodicalIF":1.6,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144722095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with intrauterine procedure for suspected retained placenta after medical termination of pregnancy in the 2nd and 3rd trimesters","authors":"Annaëlle Amous ,&nbsp;Célia Bettiol ,&nbsp;Louise Paret Perinelli ,&nbsp;Yann Tanguy Le Gac ,&nbsp;Paul Guerby ,&nbsp;Aurélie Buffeteau","doi":"10.1016/j.jogoh.2025.103000","DOIUrl":"10.1016/j.jogoh.2025.103000","url":null,"abstract":"<div><h3>Introduction</h3><div>In cases of medical termination of pregnancy (MTOP) in the second and third trimesters, incomplete placental expulsion is a common complication, often leading to intrauterine procedure. Factors associated with intrauterine procedure for suspected retained placenta after labor induction for MTOP remain poorly described. Moreover, these procedures may lead to various complications (uterine perforation, infections, secondary bleeding, intrauterine adhesions, fertility disorders). This study aims to identify these factors to support a more evidence-based use of intrauterine procedures.</div></div><div><h3>Materials and Methods</h3><div>A retrospective single-center study was conducted at Toulouse University Hospital, between January 1, 2019, and December 31, 2021. All patients who underwent labor induction for MTOP between 14 and 41 weeks of gestation were included. Maternal, obstetric, and fetal characteristics were collected and analyzed.</div></div><div><h3>Results</h3><div>A total of 371 patients were included. Gestational age was the only factor significantly associated with the performance of intrauterine procedures for suspected retained placenta (continuous variable (aOR 0.84 [0.80–0.88], <em>p</em> &lt; 0.0001) and categorical variable divided into &lt;22 weeks and ≥22 weeks of gestation (OR 0.15 [0.10–0.24], <em>p</em> &lt; 0.001)).</div></div><div><h3>Discussion</h3><div>Identifying factors associated with intrauterine procedures after MTOP in the 2nd and 3rd trimesters could lead to modified management strategies, based on gestational age, which is associated in this study, with a lower likelihood of performing intrauterine procedures beyond 22 weeks.</div></div><div><h3>Conclusion</h3><div>Gestational age was associated with the performance of intrauterine procedures for suspected retained placenta after MTOP, with a lower likelihood beyond 22 weeks of gestation.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 103000"},"PeriodicalIF":1.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baby-friendly Hospital Initiative: descriptive analysis of regional implementation, maternity units and women characteristics. The 2021 French National Perinatal Survey","authors":"Madeleine Santraine ,&nbsp;Anne Alice Chantry ,&nbsp;Camille Le Ray ,&nbsp;Caroline François ,&nbsp;Julie Boudet-Berquier ,&nbsp;Véronique Pierrat ,&nbsp;Ayoub Mitha","doi":"10.1016/j.jogoh.2025.102999","DOIUrl":"10.1016/j.jogoh.2025.102999","url":null,"abstract":"<div><div>Background: Initially created to promote breastfeeding, the Baby-Friendly Hospital Initiative (BFHI) has evolved into a broader quality-of-care approach, centered on the needs of newborns and their families. In France, BFHI adoption increased from 2 % to 17 % of maternity units between 2010 and 2024. However, it remains unclear whether structural or population characteristics influence implementation. Objective: To describe the characteristics of maternity units, women and newborns in units BFHI-accredited or in-process of accreditation, compared to non-accredited. Methods: Data were extracted from the 2021 French National Perinatal Survey, including 10,446 women who gave birth to live infants between 36 and 42 weeks of gestation in 453 maternity units. Bivariate analyses compared three groups: BFHI-accredited, in-process, and non-accredited units. Results: Among maternity units, 12 % were BFHI-accredited and 9 % were in-process. Regional implementation varied widely (0–44 % for accredited and from 0–29 % for in-process). There were no significant differences regarding maternity units’ characteristics (size, level of care, administrative status, use of temporary staff). Women's profiles were similar in terms of age, education, employment, and low-risk pregnancy. Women with high social deprivation index were less represented in accredited and in-process units compared to non-accredited (4 % and 3 % vs. 5%), as well as foreign-born women (14 % and 15 % vs. 22%). Conclusion: In France in 2021, implementation of the BFHI program in France does not appear to be associated with structural, demographic or health characteristics of units and women. Further research should explore the motivations for adopting BFHI and its effects on perinatal care practices.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 102999"},"PeriodicalIF":1.7,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between ovarian sex cord-stromal tumors and non-hormone-sensitive cancers: A nationwide nested cohort study","authors":"Sven Karstensen ,&nbsp;Kirsten Jochumsen ,&nbsp;Claus Høgdall ,&nbsp;Estrid Høgdall ,&nbsp;Niels Marcussen ,&nbsp;Finn Friis Lauszus","doi":"10.1016/j.jogoh.2025.102998","DOIUrl":"10.1016/j.jogoh.2025.102998","url":null,"abstract":"<div><h3>Background</h3><div>Ovarian sex cord-stromal cell tumors (SCSTs) are a rare group of ovarian neoplasms that include both benign and malignant diseases. Previous studies found an increased risk of breast, endometrial and ovarian cancers among women with SCSTs. However, the risk of new primary non-sex hormone-sensitive cancers remains underreported. In this study we investigated the incidence of SCSTs and the associated risks of non-sex hormone-sensitive cancers using a nested nationwide cohort in Denmark.</div></div><div><h3>Methods</h3><div>Cases were identified in the Danish National Pathology Registry and matched on birth year to a control cohort of ten women without SCSTs per case using the Danish National Patient Registry. Cancer incidence was determined using the Danish Cancer Registry. Cox proportional hazards regression assessed associations, adjusting for Charlson Comorbidity Index and socioeconomic variables.</div></div><div><h3>Results</h3><div>A total of 1387 women with SCSTs were included, with thecomas (66 %) and adult granulosa cell tumors (26 %) being the most common subtypes. There was an overall increased rate of new primary malignancy (excluding breast, endometrial and ovarian cancers) among women with SCST (HR = 1.36, 95 % CI: 1.16–1.6). Increased rates of malignant melanoma (HR = 1.52, 95 % CI: 1.14–2.03) and lung cancer (HR = 1.2, 95 % CI: 1.01–1.42) were observed in women with thecomas, whereas other SCST subtypes showed no significant associations with risk of new primary cancers.</div></div><div><h3>Conclusion</h3><div>Overall women with SCSTs have a slightly increased rates of non-hormone-sensitive malignancies, whereas women with thecomas showed marginally elevated rates of lung cancer and melanoma.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 102998"},"PeriodicalIF":1.7,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of single-site to multi-port laparoscopic hysterectomy in patients with benign or malignant gynecological diseases: A meta-analysis of 3309 patients","authors":"María Inés Nava Silerio ,&nbsp;Valeria García Aguayo ,&nbsp;Alba Alicia Esparza Guzmán ,&nbsp;Daena Guadalupe Muñoz Cruz ,&nbsp;Jesús Iván Rivera Cantero ,&nbsp;José Rafael Aguilar González ,&nbsp;Jennifer Pineda ,&nbsp;Daniel Suárez ,&nbsp;Diego Pichardo Rojas ,&nbsp;Adela Hernández Martínez","doi":"10.1016/j.jogoh.2025.102997","DOIUrl":"10.1016/j.jogoh.2025.102997","url":null,"abstract":"<div><h3>Background</h3><div>This meta-analysis evaluates the benefits of single-site laparoscopy hysterectomy (SS-LH) compared to conventional multi-port laparoscopy (MP-LH). Although SS-LH offers cosmetic and less invasive advantages, the efficacy and safety results in existing studies remain inconsistent.</div></div><div><h3>Objective</h3><div>We aimed to compare the outcomes of SS-LH and MP-LH in patients with benign and malignant gynecological diseases, focusing on the benefits of each modality.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, we conducted searches in PubMed, Cochrane CENTRAL, and Embase for randomized controlled trials (RCTs) and cohort studies up to March 5, 2024. We included studies comparing SS-LH and MP-LH, analyzing outcomes like complications, bleeding volume, operative time, length of stay, uterus weight, conversion rate, postoperative pain, fever, port site infection, and port hernia.</div></div><div><h3>Results</h3><div>The analysis included 3309 patients. SS-LH was associated with fewer complications (RR=0.46, <em>p</em> = 0.0005) and shorter operative time (MD=13.70 min , <em>p</em> = 0.02). No significant differences were found for blood loss, length of stay, uterus weight, conversion rate, postoperative pain, fever, port site infection, or port hernia.</div></div><div><h3>Conclusion</h3><div>SS-LH demonstrates lower complication rates and shorter operative time compared to MP-LH. Both procedures are safe and effective, but larger multicentric randomized trials are needed to establish SS-LH as the standard of care.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 102997"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Surgical indications for perineal surgery during prolapse surgery","authors":"Emmanuel Delorme ,&nbsp;Aurélie Guyomard","doi":"10.1016/j.jogoh.2025.102996","DOIUrl":"10.1016/j.jogoh.2025.102996","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 7","pages":"Article 102996"},"PeriodicalIF":1.7,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who stays overnight? A multicenter study of hospital discharge timing after laparoscopic management of ectopic pregnancy","authors":"Abdelrahman Yousif ,&nbsp;Mohanad Elchouemi","doi":"10.1016/j.jogoh.2025.102995","DOIUrl":"10.1016/j.jogoh.2025.102995","url":null,"abstract":"<div><h3>Background</h3><div>Same-day discharge (SDD) following laparoscopic treatment of ectopic pregnancy has gained increasing interest due to its potential to enhance patient satisfaction, reduce healthcare costs, and optimize hospital resources. However, limited data exist on predictors of non-SDD in this population.</div></div><div><h3>Objective</h3><div>To identify patient- and procedure-related factors associated with overnight admission following laparoscopic management of ectopic pregnancy.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. We included patients who underwent laparoscopic salpingectomy with complete data on discharge status. SDD was defined as discharge on the day of surgery. Multivariable logistic regression was used to identify independent predictors of overnight stay, adjusting for age, race, BMI, ASA class, hypertension, diabetes, and anemia. Missing data were handled using multiple imputation.</div></div><div><h3>Results</h3><div>Among 10,162 patients, 6245 (61 %) were discharged the same day. Blood transfusion (aOR 6.37, 95 % CI 4.98–8.15) and operative time ≥180 min (aOR 4.04, 95 % CI 1.63–10.03) were strongly associated with increased odds of overnight admission. Hispanic ethnicity (aOR 1.27, 95 % CI 1.12–1.45) and elevated creatinine (aOR 1.74, 95 % CI 0.93–3.24) were also associated, though the latter did not reach statistical significance. Higher BMI and lower hematocrit were more frequent among non-SDD patients.</div></div><div><h3>Conclusions</h3><div>Most patients undergoing laparoscopic treatment for ectopic pregnancy can be safely discharged the same day. Blood transfusion, prolonged operative time, and select preoperative characteristics increase the likelihood of overnight admission. These findings may inform perioperative planning and enhance patient selection for safe SDD protocols.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 102995"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive factors of ectopic pregnancy among patient followed up for pregnancy of unknown location: management optimization with endometrial thickness ?","authors":"Dr Cohen Adrien, Dr Margueritte François, Dr Poupon Clotilde, Dr Armengaud Camille, Pr Fauconnier Arnaud, Dr Bailleul Alexandre","doi":"10.1016/j.jogoh.2025.102994","DOIUrl":"https://doi.org/10.1016/j.jogoh.2025.102994","url":null,"abstract":"<p><strong>Introduction: </strong>Ectopic pregnancies (EP) represent 2% of pregnancies. Delayed diagnosis due to inadequate initial management of pregnancies of unknown location (PUL) is common. This study aimed to identify predictive factors for EP during the initial management of PULs, focusing on endometrial thickness (ET).</p><p><strong>Method: </strong>A retrospective study (January 2020-March 2022) analyzed PUL patients at CHIPS Hospital. Clinical, biochemical, and ultrasound data, including ET and hCG ratio were analyzed. The hCG ratio was defined as the serum β-hCG level at 48 hours divided by the baseline level. Logistic regression identified predictors of EP, and the diagnostic performance was evaluated using the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Among 208 patients, 67 (32.2%) were diagnosed with EP. ET was significantly thinner in the EP group compared to non-EPs (8.6 mm vs. 13.6 mm, p < 0.01). The hCG ratio differed between groups, with EPs showing a mean ratio of 1.28 compared to declining ratios in miscarriages (0.52) and increasing ratios in intrauterine pregnancies (2.19, p < 0.01). An ET threshold of <10 mm maximized diagnostic accuracy, yielding a sensitivity of 79%, specificity of 70%, and AUC of 0.80. Multivariate analysis identified ET <10 mm (OR = 13.17, 95% CI: 5.59-31, p < 0.001) and hCG ratio (1-2) (OR = 35.37, 95% CI: 7.12-175, p < 0.001) as independent predictors of EP. The final model achieved an AUC of 0.85.</p><p><strong>Conclusion: </strong>Endometrial thickness < 10 mm and an HCG ratio between 1 and 2 appear associated with EP in PUL patients. Integrating ET into diagnostic protocols could improve early detection and management, particularly in resource-limited settings. Prospective studies are needed to validate these findings and refine diagnostic algorithms.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"102994"},"PeriodicalIF":1.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra partum fever in term pregnancies: Predictive factors of poor neonatal outcome","authors":"Stanley Soussan ,&nbsp;Charles Egloff ,&nbsp;Justine Raveau ,&nbsp;Laurent Mandelbrot ,&nbsp;Olivier Picone ,&nbsp;Jeanne Sibiude","doi":"10.1016/j.jogoh.2025.102993","DOIUrl":"10.1016/j.jogoh.2025.102993","url":null,"abstract":"<div><h3>Background</h3><div>Elevated maternal temperature during labor is common, affecting up to 7 % of women in labor and can be harmful for the neonate.</div></div><div><h3>Objective</h3><div>To determine factors predictive of poor neonatal outcomes in case of intrapartum fever in term pregnancies.</div></div><div><h3>Study design</h3><div>We performed a single center retrospective study, from January 1, 2020 to June 30, 2022 of parturients ≥ 36 weeks of gestation with intrapartum fever defined as at least one temperature ≥ 38.0 °C during labor. Three groups were compared according to the severity of temperature observed during labor. The primary outcome was any maternal or neonatal characteristics associated with poor neonatal outcome (at least one of the following criteria: 5 min Apgar score &lt; 7, umbilical artery pH &lt; 7.1, acute respiratory distress, neonatal intensive care unit admission, hypoxic-ischemic encephalopathy, suspected early-onset neonatal sepsis).</div></div><div><h3>Results</h3><div>The incidence of fever was 3.0 %. Two hundred and thirty-eight patients were included: 106 (44.5 %) had only one temperature between 38.0 and 39.0 °C (“low fever”), 109 (45.8 %) with at least two temperatures between 38.0 and 39.0 °C (“mild fever”) and 23 (9.7 %) with at least one temperature ≥ 39.0 °C (“severe fever”). Fifty-five neonates (23.1 %) had poor neonatal outcome. In univariate analysis, only high maternal fever ≥ 39.0 °C (18.1 % vs 7.1 %, <em>p</em> &lt; 0.05) and early onset fever during labor (41.0 % vs 23.6 % <em>p</em> &lt; 0.05) were associated with a poor neonatal outcome. In multivariate analysis, no predictive factor remained significantly associated with poor neonatal outcome.</div></div><div><h3>Conclusion</h3><div>High maternal fever and/or early onset of fever during labor may be associated with poor neonatal outcome.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"54 8","pages":"Article 102993"},"PeriodicalIF":1.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}