Journal of gynecology obstetrics and human reproduction最新文献

{"title":"Ultra-portable ultrasound for third-trimester care: diagnostic performance of the echOpen O1 operated by midwives in rural Senegal.","authors":"Billo Tall, Amadou Moustapha Ndoye, Sokhna Dieng, Marguerite Diatta, Aboubacry Gaye, Mame Astou Gassama, Mamadou Cissé, Abdourahmane Sow, Doudou Diallo, Amy Gueye, Pape Samba Dia, Jean-Elie Malkin, Christine Beyrouty, Clément Le Couedic, Mehdi Benchoufi, José Francisco Fernandes, Cheikh Talla, Cheikh Loucoubar, Yoann Athiel, Fatoumata Diène","doi":"10.1016/j.jogoh.2026.103306","DOIUrl":"https://doi.org/10.1016/j.jogoh.2026.103306","url":null,"abstract":"<p><strong>Background: </strong>Obstetric ultrasound is central to antenatal care, but access remains limited in many low- and middle-income settings. Ultra-portable devices may extend access to basic obstetric imaging and support midwife-led care.</p><p><strong>Objective: </strong>To assess the diagnostic performance of the echOpen O1 ultra-portable ultrasound probe for selected obstetric targets during antenatal follow-up in Senegal.</p><p><strong>Methods: </strong>We conducted a prospective, multicentre pilot diagnostic agreement study in two health facilities in the Sokone health district, Fatick region, from November 2023 to August 2024. Pregnant women at 37 weeks of gestation or more were included. Each participant underwent three ultrasound examinations: two performed by the same midwife using echOpen O1 and a standard ultrasound device in a randomly assigned order, and one blinded echOpen O1 examination performed by a second midwife. Images and short video clips were reviewed by a reference radiologist. Agreement was assessed for foetal number, foetal presentation, foetal cardiac activity and placental location.</p><p><strong>Results: </strong>Among 221 included women, 214 were analysed. Overall agreement for the core targets between echOpen O1 and standard ultrasound (intra-operator) was 99.5% (95% CI, 98.6-100). Intra-operator agreement was 99.5% (95% CI, 98.6-100) for foetal presentation, 100% (95% CI, 100-100) for foetal number, placental location and foetal cardiac activity. Expert review confirmed intra-operator agreement above 95% for all targets.</p><p><strong>Conclusion: </strong>The echOpen O1 probe showed performance comparable with standard ultrasound for basic third-trimester obstetric assessments, supporting its potential to strengthen antenatal care in resource-limited settings.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"103306"},"PeriodicalIF":1.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Universal single-step warming of vitrified blastocysts: feasibility across two commercial kits and comparison with the conventional warming procedure.","authors":"Yingzhuo Gao, Lodovico Parmegiani, Gabor Vajta, Da Li","doi":"10.1016/j.jogoh.2026.103304","DOIUrl":"https://doi.org/10.1016/j.jogoh.2026.103304","url":null,"abstract":"<p><p>Conventional vitrification systems for human gametes and embryos typically necessitate brand-specific warming solutions. This retrospective longitudinal cohort study on 2,563 vitrified/warmed blastocysts investigates the efficacy of a universal single-step warming (USSW) protocol for human blastocysts vitrified using distinct commercial systems, combining vitrification and warming kits from two manufacturers: Kitazato (Japan) and VitaVitro Biotech (China) according two different warming protocols: the conventional protocol (UW) or with the single-step warming (USSW). Cryo-survival was 100% across all groups. Clinical and ongoing pregnancy, miscarriage, and live birth rates were comparable among groups. Implantation rate differed overall (p = 0.03), but no pairwise differences remained significant after Bonferroni correction. This study provides preliminary evidence suggesting that the universal single-step warming (USSW) protocol may simplify kit interchangeability and shorten the warming procedure.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"103304"},"PeriodicalIF":1.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluoroscopy in the treatment of severe Asherman syndrome.","authors":"Eva Dreisler, Bent Brandt Hansen, Jens Joergen Kjer","doi":"10.1016/j.jogoh.2026.103305","DOIUrl":"https://doi.org/10.1016/j.jogoh.2026.103305","url":null,"abstract":"<p><p>Asherman syndrome is an acquired condition with both subjective symptoms and objective findings. Most cases occur after intrauterine instrumentation shortly after pregnancy. The syndrome may be associated with subfertility, infertility, recurring miscarriage and obstetric complications. The main clinical symptoms are hypomenorrhea or amenorrhea and cyclic pelvic pain. The presence of intrauterine adhesions is crucial for the diagnosis Asherman syndrome. The treatment of Asherman syndrome is hysteroscopic adhesiolysis attempting to improve fertility and obstetric outcome. The procedure may in severe cases be challenging and need guidance in different techniques, e.g. intraoperative fluoroscopy, transabdominal ultrasonography or laparoscopy. In this review, we explore the evidence of benefits and potential risks of the intraoperative fluoroscopic guidance in hysteroscopic adhesiolysis. Embase and Medline were searched from 1974 to February 2026. We found 617 papers in the literature search. Duplicates, conference abstracts and irrelevant papers were excluded. As a result, 26 papers from the search were included in this review. After fluoroscopically guided hysteroscopic adhesiolysis there is high success rate of restoring uterine anatomy and improving menstrual pattern. Reproductive outcomes vary with reported pregnancy rates from 75-87% and live birth rates from 63-68%. Pregnancies after hysteroscopic adhesiolysis are associated with an increased risk of placenta accreta spectrum. Radiation exposure associated with fluoroscopy was found to be minimal, with median exposure times and dose levels well within safe limits.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"103305"},"PeriodicalIF":1.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Letter Response: Reliability and validity of the 30-second chair-stand test for assessing functional capacity in women with endometriosis: a cross-sectional and longitudinal study\".","authors":"Georgia De Loza","doi":"10.1016/j.jogoh.2026.103303","DOIUrl":"https://doi.org/10.1016/j.jogoh.2026.103303","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"103303"},"PeriodicalIF":1.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fertility after colorectal surgery for endometriosis comparing conventional laparoscopy and robotic assisted laparoscopy Should all patients benefit from robotic approach?","authors":"Eric de Labrouhe, Yohann Dabi, Meryl Dahan, Clément Ferrier, Cyril Touboul, Emile Darai, Adrien Crestani","doi":"10.1016/j.jogoh.2026.103298","DOIUrl":"https://doi.org/10.1016/j.jogoh.2026.103298","url":null,"abstract":"<p><strong>Aim: </strong>The first objective was to present fertility outcomes following surgery for deep endometriosis with colorectal involvement at an expert endometriosis center, and to compare conventional laparoscopy with robotic-assisted laparoscopy. Secondary objectives included an analysis of pregnancy and obstetric outcomes.</p><p><strong>Methods: </strong>We conducted a retrospective, monocentric cohort study involving patients who underwent surgery for endometriosis between February 2019 and January 2023, with colorectal resection and wishing to become pregnant either before surgery or in the immediate postoperative period.</p><p><strong>Results: </strong>Among the 72 patients wishing to conceive, 23/34 patients (68%) in the robotic-assisted laparoscopy group achieved pregnancy, compared to 25/38 patients (66%) in the conventional laparoscopy group (not significant (NS)). Spontaneous pregnancies occurred in 11/23 patients (48%) and 9/25 patients (36%), respectively (NS). Among those who achieved pregnancy, 18/23 patients (78.3%) in the robotic-assisted laparoscopy group and 21/25 patients (84%) in the conventional laparoscopy group had at least one live birth (NS).</p><p><strong>Conclusion: </strong>Our findings suggest that surgery for deep endometriosis with colorectal involvement, whether performed via robotic-assisted or conventional laparoscopy, yields similar postoperative fertility outcomes.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":" ","pages":"103298"},"PeriodicalIF":1.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clitoroplasty and urogenital sinus mobilization in females with congenital adrenal hyperplasia: A case report with focused literature discussion","authors":"Faruk Abike,&nbsp;Fatma Basak Tanoglu,&nbsp;Bashar Yacoub Abdelhafiz Sammour","doi":"10.1016/j.jogoh.2026.103134","DOIUrl":"10.1016/j.jogoh.2026.103134","url":null,"abstract":"<div><h3>Introduction</h3><div>Congenital adrenal hyperplasia (CAH) can result in masculinized genitalia due to excessive androgen production. This genital virilization often presents as clitoral hypertrophy, ranging from a significantly enlarged clitoris to a phallic-like clitoris in female patients.</div></div><div><h3>Case presentation</h3><div>A Syrian refugee girl presented at age 24 with complaints of abnormal genitalia. Gynecologic examination revealed clitoromegaly, absence of labia minora, and a single common orifice of the urethra and vagina, the size of a pinhead. Nerve-sparing clitoroplasty, total urogenital sinus mobilization, vaginoplasty, and creation of labia minora with perineoplasty were performed.</div></div><div><h3>Conclusions</h3><div>There are limited case reports on CAH, clitoroplasty, and urogenital sinus mobilization in adults. This case highlights the feasibility of one-stage feminizing genitoplasty in adulthood and provides unique educational value through detailed step-by-step surgical video documentation.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 5","pages":"Article 103134"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful live birth following robotic-assisted management of a cesarean scar pregnancy: a promising pathway","authors":"Antonella Iannaccone ,&nbsp;Paul Buderath ,&nbsp;Martin W. Britten ,&nbsp;Alberto Spina ,&nbsp;Katharina Krempel ,&nbsp;Zeynep Atas Elfrink ,&nbsp;Angela Köninger ,&nbsp;Rainer Kimmig ,&nbsp;Roland Csorba","doi":"10.1016/j.jogoh.2026.103131","DOIUrl":"10.1016/j.jogoh.2026.103131","url":null,"abstract":"<div><div>Cesarean scar pregnancy (CSP) is a variant of uterine ectopic pregnancy defined by full or partial implantation of the gestational sac in the scar of a previous cesarean section. The most usual recommendation is termination of pregnancy in the first trimester.</div><div>In this article, we present a case of live birth after detecting CSP in early pregnancy and robotic scar reinforcement surgery, effectively relocating the pregnancy into the cavum. At 25+3 gestational weeks, an emergency caesarean section was performed. A girl weighing 800 g was delivered with APGAR 7/7/9. The percrete area of the placenta was excised and the uterus could be preserved.</div><div>Prolongation of CSP and consecutive live birth is feasible and can be achieved. Using robotic surgical approach for both the scar reinforcement surgery as well as the surveillance of the pregnancy including caesarean section with management of placenta percreta require high expertise and specialized centres.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 5","pages":"Article 103131"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doppler ultrasound at 41 weeks: Pragmatic evidence, clinical relevance, and response to methodological considerations","authors":"Jeremy Boujenah,&nbsp;Bruno Carbonne","doi":"10.1016/j.jogoh.2026.103125","DOIUrl":"10.1016/j.jogoh.2026.103125","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 4","pages":"Article 103125"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal alcohol exposure and sonographic abnormalities: Insights from a retrospective cohort","authors":"Margaux Sizaire ,&nbsp;Lucie Galvan ,&nbsp;Violaine Peyronnet ,&nbsp;Emilia Holmström ,&nbsp;Charles Egloff ,&nbsp;Victoire Pauphilet ,&nbsp;Oliver Picone ,&nbsp;Laurent Mandelbrot ,&nbsp;Imane Ben M’Barek","doi":"10.1016/j.jogoh.2026.103124","DOIUrl":"10.1016/j.jogoh.2026.103124","url":null,"abstract":"<div><h3>Context</h3><div>Foetal Alcohol Syndrome (FAS) is the most severe form of Foetal Alcohol Spectrum Disorders (FASD), caused by prenatal alcohol exposure, a major preventable cause of congenital disability. FASD lack specific prenatal ultrasound signs, making early diagnosis difficult.</div></div><div><h3>Objective</h3><div>To describe prenatal ultrasound findings in pregnancies with reported alcohol use and compare maternal and neonatal characteristics according to the presence of anomalies.</div></div><div><h3>Methods</h3><div>We conducted a retrospective multicentre study in three hospitals from September 2013 to April 2025. All women reporting alcohol use during pregnancy were included. Exposure was classified by quantity (moderate: ≤3 drinks/day or &lt;40 cl/day; excessive: &gt;3 drinks/day or &gt;40 cl/day) and frequency (occasional, often, chronic), based on maternal self-report. Ultrasound scans from all trimesters were reviewed for growth and morphological anomalies. Comparative analyses were performed between women with and without anomalies.</div></div><div><h3>Results</h3><div>Among 94 pregnancies, 30 (32%) showed ultrasound anomalies. Women with anomalies were older (33.9 vs. 31.7 years, p &lt;0.01), with no differences in BMI, parity, or co-exposures. Occasional alcohol use appeared not associated with anomalies, whereas increasing maternal age (aOR = 1.22; 95% CI [1.09-1.40]) was an independent risk factor. Most anomalies were detected in the second trimester, mainly foetal growth restriction (FGR) and microcephaly. Neonatal abnormalities occurred in 70% of the anomaly group versus 10.9% without anomalies (p &lt; 0.01). Seven neonates (11%) had undiagnosed FGR or microcephaly at birth.</div></div><div><h3>Conclusion</h3><div>Ultrasound anomalies were found in one-third of alcohol-exposed pregnancies, underscoring the risks of chronic alcohol use.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 4","pages":"Article 103124"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinents of spontaneous labor for prolonged pregnancy and effectiveness of membrane sweeping: An observational study","authors":"Vincent Marcoux ,&nbsp;Marie De Antonio ,&nbsp;Amélie Delabaere ,&nbsp;Marie Accoceberry ,&nbsp;Céline Houlle ,&nbsp;Pamela Bouchet ,&nbsp;Fanny Petillon ,&nbsp;Marion Rouzaire ,&nbsp;Denis Gallot","doi":"10.1016/j.jogoh.2026.103132","DOIUrl":"10.1016/j.jogoh.2026.103132","url":null,"abstract":"<div><h3>Background</h3><div>Prolonged pregnancy is associated with an increased risk of maternal, fetal and neonatal complications. Careful monitoring and systematic induction at 42 weeks of gestation are recommended in France.</div></div><div><h3>Objectives</h3><div>Our primary objective was to identify determinants for spontaneous labor during expectant management for prolonged pregnancy. Our secondary objective was to assess the efficacy of membrane sweeping in bringing on labor.</div></div><div><h3>Study design</h3><div>This observational, retrospective, monocentric study included all patients with a singleton pregnancy who had reached the term of 41 weeks of gestation to within one day. They underwent an expectant period up to 41 weeks and 6 days with fetal heart monitoring and ultrasound every two days. The cohort was divided into two groups according to the presence or absence of membrane sweeping. In the group that did not undergo membrane sweeping (Natural History cohort), we compared patients who entered spontaneous labor with those who required induction of labour.</div></div><div><h3>Results</h3><div>A total of 366 patients were included. For the 293 patients without membrane sweeping, spontaneous labor occurred in 51.1 % of cases. A higher Bishop score (<em>p</em> = 0.02) and a lower BMI (<em>p</em> = 0.08) were associated with spontaneous labor. Parity had no influence (<em>p</em> = 0.74). Effectiveness of membrane sweeping to promote spontaneous labor was highlighted after adjustment on parity, BMI and Bishop score (71.6 % vs 51.5 %, <em>p</em> = 0.021, SMD=0.422).</div></div><div><h3>Conclusion</h3><div>In prolonged pregnancy, the probability of going into spontaneous labor was only 50.9 %. Low BMI and high Bishop score were associated with spontaneous onset of labor in case of expectant management. Membrane sweeping was associated with spontaneous labor in our post-term population after adjustment on parity, BMI and Bishop score.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 4","pages":"Article 103132"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}