{"title":"A Comprehensive Review on Recent Advances of Remarkable Scaffold Triazole based Schiff Base: Synthesis and Photoresponsive Chemosensors for Al<sup>3+</sup> Ion Detection.","authors":"Umme Salma, Md Zafer Alam, Suhail Ahmad, Md Mohasin, Salman A Khan","doi":"10.1007/s10895-025-04202-4","DOIUrl":"https://doi.org/10.1007/s10895-025-04202-4","url":null,"abstract":"<p><p>Triazole Schiff base as fluorescent chemosensor and fluorogenic cation sensor is crucial for the detection of metal ions. The diverse structures of triazole Schiff bases have raised concerns. Excellent luminous properties are produced by mixing donor and acceptor groups with delocalized π-orbitals due to the intramolecular charge transfer (ICT) mechanism. For Al<sup>3+</sup> metal ions, this work provides data on the triazole Schiff base, design, synthesis, and sensing mechanism (ON/OFF, OFF/ON, and ON-OFF-OFF) of these sensors, as well as their potential uses. We also examined how the sensor's photophysical characteristics alter when it coordinates with the metal ions, leading to modifications in its usual sensing behaviour, such as a shift from hypsochromic/bathochromic or hypochromic/hyperchromic. Researchers will use this review as a starting point to investigate triazole Schiff base-based sensors further.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ratiometric Fluorescence Sensor for On-Off Detection Vitamin B2 and Hexavalent Chromium Based on Silicon Quantum Dots.","authors":"Chaofan Jia, Yehao Yan, Fengjiao Zhang, Xinqiu Xu, Hao Li, Jing Zhang, Yin Wei","doi":"10.1007/s10895-025-04256-4","DOIUrl":"https://doi.org/10.1007/s10895-025-04256-4","url":null,"abstract":"<p><p>Silicon quantum dots (SiQDs) function as ratiometric fluorescent sensors for detecting Vitamin B<sub>2</sub> (VB<sub>2</sub>) and Cr<sup>6+</sup>, exhibiting an on-off response. Upon introducing VB<sub>2</sub> to the SiQDs solution, the blue emission peak of SiQDs at 445 nm gradually decreases, while the yellow emission peak at 520 nm, associated with VB<sub>2</sub>, increases gradually. In the presence of Cr<sup>6+</sup>, both the blue and yellow fluorescence diminish. Through the utilization of Fluorescence Resonance Energy Transfer (FRET), we developed ratiometric fluorescent sensors that displayed specificity and sensitivity in detecting VB<sub>2</sub> and Cr<sup>6+</sup>. The linear detection ranges for VB<sub>2</sub> and Cr<sup>6+</sup> were found to be 0.2 µM to 0.8 µM and 2 µM to 18 µM, respectively. Limit of detection (LOD) was determined to be 1.43 nM for VB<sub>2</sub> and 0.75 µM for Cr<sup>6+</sup> (based on 3 s/k, LOD). With a short response time, good selectivity, and resistance to interference, the recovery rate in lake water ranges from 84.8 to 98.0%.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Facile Synthesis of Stable and Highly Luminescent MAPbI<sub>3</sub> Perovskite Quantum Dots.","authors":"Khurshid Tashpulatov, Kodirbek Norboev, Doston Toshpulatov, Shukhrat Magdiev, Abdullo Nasimov, Sherzodbek Mirzaev, Jamshid Ruziev, Bahodir Yakubov","doi":"10.1007/s10895-025-04258-2","DOIUrl":"https://doi.org/10.1007/s10895-025-04258-2","url":null,"abstract":"<p><p>The colloidal synthesis of halide perovskite quantum dots has been extensively studied due to their superior optical properties. However, synthesizing stable iodide-based perovskite quantum dots continues to pose challenges. In this work, by choosing an alternative solvent among several preferences such as dimethylformamide (DMF), dimethylsulfoxide (DMSO), and acetonitrile (ACN) as a solvent to form the precursor MAPbI<sub>3</sub>, and using an antisolvent suitable for this precursor, obtaining perovskite quantum dots with a stable MAPbI<sub>3</sub> structure was achieved. The synthesized MAPbI<sub>3</sub> perovskite quantum dots were found to maintain their bright red luminescence for over 8 months. The spectral properties of synthesized MAPbI<sub>3</sub> quantum dots were investigated using electronic absorption and fluorescence spectroscopies.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuewei Fang, Tielong Wang, Yinjie Zhang, Jingli Song
{"title":"Dual-Functional Silicon-Based Nanofluorescent Platform for Iron Detection and Capecitabine Delivery in Colorectal Cancer Treatment.","authors":"Xuewei Fang, Tielong Wang, Yinjie Zhang, Jingli Song","doi":"10.1007/s10895-025-04252-8","DOIUrl":"https://doi.org/10.1007/s10895-025-04252-8","url":null,"abstract":"<p><p>Colorectal cancer (CRC) poses significant challenges due to its high incidence and mortality. Addressing limitations like poor bioavailability and off-target effects of traditional chemotherapy, we engineered PDMS-CP1@1@Capecitabine nanoparticles. This novel formulation incorporates a gadolinium-based coordination polymer synthesized via a hydrothermal reaction with a thiourea Schiff-base ligand and embedded in a polydimethylsiloxane (PDMS) matrix, enhanced by the bioactive compound 1 from actinomycetes. Structural characterization demonstrated a crystalline nature with distinct XRD peaks at 21.4° and 25.6°, alongside remarkable fluorescence with peak emission at 444 nm and superior Fe<sup>3+</sup> selectivity, showing 90% quenching efficiency against Fe<sup>3+</sup> compared to other ions. These nanoparticles reduced CRC cell viability by up to 55% at 20 µg/mL, modulating USP22 and HSP90 expression, validated by molecular docking confirming hydrogen bonding interactions. PDMS-CP1@1@Capecitabine emerges as a potent targeted therapy for CRC, enhancing drug delivery and offering a novel approach for iron monitoring, pivotal for personalized treatment strategies.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"1,4-Dihydropyrrolo[3,2-b]Pyrroles Containing New A-D-A System: Synthesis and Investigation of Their Photophysical Properties.","authors":"Guler Yagiz Erdemir","doi":"10.1007/s10895-025-04240-y","DOIUrl":"https://doi.org/10.1007/s10895-025-04240-y","url":null,"abstract":"<p><p>Herein, new tetraarylpyrrolo[3,2-b]pyrroles (TAPP) containing different substituents (4a-c, 5a-c) on the N-phenyl rings were synthesized in high yields using a one-pot method. The 3,6 positions of the pyrrolopyrol ring of the 4a-c compound were formylated by Vilsmeier-Haack reaction to synthesize a new pyrrolopyrol compound containing the acceptor-donor-acceptor (A-D-A) system (5a-c). The photophysical properties of all obtained derivatives were investigated in different solvents. According to the results obtained, the absorptions of derivatives 4a-c were recorded around 400 nm and their emission intensities appeared around 450 nm. The absorption intensities of derivatives 4b and 5b were recorded as 400 nm and 350 nm, respectively, while their emission intensities were observed as 455 and 440. In the A-D-A system formed as a result of the bonding of electron-withdrawing formyl groups at position 3,6 of the TAPP structure, a high Stokes shift occurred, while 50 nm hypsochromic shifts were observed in its absorption.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Efficient ICT-Based Ratiometric Molecular Chameleon for the Detection of Sarin Surrogte, Diethylchlorophosphate.","authors":"Shreya Ali, Sabbir Ahamed, Najmin Tohora, Jyoti Chourasia, Manas Mahato, Shubham Lama, Shraddha Rai, Susanta Ghanta, Sudhir Kumar Das","doi":"10.1007/s10895-025-04244-8","DOIUrl":"https://doi.org/10.1007/s10895-025-04244-8","url":null,"abstract":"<p><p>The significant toxicity associated with organophosphates (OPs) nerve agents represents a substantial threat to both public health and national security. This extensive report presents a colorimetric probe, DPAB, for the identification of sarin mimic, diethylchlorophosphate (DCP) in both liquid and vapor phases. The initial yellow coloration of the DPAB solution gradually changes into a visible pink color due to the progressive accumulation of DCP, highlighting the effectiveness of DPAB as a colorimetric sensor. The characteristic pink coloration of the DPAB-DCP solution is completely reverted to the original yellow hue of free DPAB through the gradual and systematic introduction of triethylamine (TEA). The detection and quantification limit of DPAB is found to be in the nanomolar (nM) range. Additionally, we have developed a paper strip test kit as a practical application, enabling the immediate detection and measurement of DCP in actual threat situations. Furthermore, we also conducted experiments using dipstick and dip-vial conical flask to identify DCP vapor. The implementation of a smartphone-based readout technique facilitates the accurate measurement of DCP in isolated locations. Mechanistic aspects have been unveiled through density functional theoretical analysis. Our probe DPAB holds a promising candidate for environmental toxicology upon exposure to these hazardous nerve agents.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pravinkumar Selvam, Ashok Kumar S K, Kiran B Manjappa
{"title":"Microwave-Assisted Synthesis of Phenyl Quinazoline: Investigation 'ON-OFF-ON' and Latent Fingerprint Applications.","authors":"Pravinkumar Selvam, Ashok Kumar S K, Kiran B Manjappa","doi":"10.1007/s10895-025-04251-9","DOIUrl":"https://doi.org/10.1007/s10895-025-04251-9","url":null,"abstract":"<p><p>Stimuli-responsive materials with donor-acceptor (D-A) systems have significant potential for sensing toxic analytes in solution and solid state. In this regard, a new probe, N, N-dimethyl-4-(4-phenylquinazolin-2-yl) aniline (DAQ), was synthesized using microwave irradiation and characterized using various spectroscopic techniques. The crystal structure analysis revealed that DAQ crystallized in a monoclinic system with a P21/m space group. The probe exhibits fluorescence properties in solid state and solution, with positive solvatochromism observed as solvent polarity increased from hexane to DMF, indicating the existence of D-A structural units. The probe DAQ, exhibited reversible switching behaviour in the solution and solid state, indicating its sensitivity to volatile trifluoroacetic acid (TFA) and triethylamine (TEA) as confirmed by spectrophotometric and spectrofluorimetric studies. The binding constant of probe DAQ with TFA and TEA were studied by the Benesi Hildebrand (BH) plot using UV-Vis spectral titration. The estimated association constant was found to be 1.43 × 10<sup>4</sup> M<sup>- 1</sup>. The DAQ aggregation-enhanced emission properties have been successfully utilized to develop security ink and latent fingerprint information encryption on various substrates in their aggregated solid state. The study reveals that the sensitivity of DAQ warrants application on all forms of forensic evidence.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction Note: A New Luminescent Zn(II) Complex: Selective Sensing of Cr<sub>2</sub>O<sub>7</sub><sup>2</sup> <sup>-</sup> and Prevention Activity Against Orthodontic Root Absorption by Suppressing Inflammatory Response.","authors":"Yan-Feng Zhu, Wei-Qun Guan, Fei Lin, Wei-Hui Chen","doi":"10.1007/s10895-025-04264-4","DOIUrl":"10.1007/s10895-025-04264-4","url":null,"abstract":"","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical Investigation of DNA Behaviour in Flow using Confocal Detection Incorporated with Fluorescence Correlation Spectroscopy (FCS).","authors":"Fatma Doğan Güzel, Hamed Ghorbanpoor","doi":"10.1007/s10895-025-04263-5","DOIUrl":"https://doi.org/10.1007/s10895-025-04263-5","url":null,"abstract":"<p><p>Investigation of the behavior of biopolymers in flow such as Deoxyribonucleic acid (DNA), is a critical challenge in engineering, polymer, and life sciences. In this study, we studied the rheological properties of DNA and flow characteristics in real-time. The velocity measurement was carried out using confocal detection incorporated with Fluorescence Correlation Spectroscopy (FCS). Optical experiments provided an understanding of the diffusion- and flow-dominated regimes for molecules treated in microfluidic channels and lab-on-chip devices in general. We found that the flow-dominated regime starts at a flow rate of 0.3 µl/min and the transitional regime falls into 0.02-0.3 µl/min flow rates. There are a few examples for the detection of DNA and different fragments in flow as such. It is therefore believed to provide valuable insights into the subject of flow dynamics of DNA.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pham Van Duong, Le Anh Thi, Phung Quang Hung, Le Duc Toan, Pham Thi Chuyen, Do Minh Hieu, Pham Hong Minh, Nguyen Thanh Binh, Tran Manh Cuong, Nguyen Minh Hoa
{"title":"Probing Förster Resonance Energy Transfer in Carbon Quantum Dots for High-Sensitivity Aflatoxin B1 Detection.","authors":"Pham Van Duong, Le Anh Thi, Phung Quang Hung, Le Duc Toan, Pham Thi Chuyen, Do Minh Hieu, Pham Hong Minh, Nguyen Thanh Binh, Tran Manh Cuong, Nguyen Minh Hoa","doi":"10.1007/s10895-025-04246-6","DOIUrl":"https://doi.org/10.1007/s10895-025-04246-6","url":null,"abstract":"<p><p>Carbon quantum dots (CQDs), with their remarkable optical properties such as strong fluorescence and biocompatibility, are emerging as versatile tools in biosensing and food safety monitoring. This study investigates binding-induced Förster resonance energy transfer (FRET) between CQDs as donors and aflatoxin B1 (AFB1), a highly toxic mycotoxin, as the acceptor. Spherical CQDs, averaging 4.56 nm in diameter and emitting fluorescence at 455 nm, were synthesized for this purpose. Fluorescence spectroscopy, incorporating Stern-Volmer analysis and time-resolved lifetime measurements, revealed the critical role of FRET in this interaction. The estimated Förster radius (R<sub>0</sub>) of 4.81 nm and donor-acceptor separation distance (r) of 5.12 nm corresponded to a FRET efficiency of 46%. The observed decrease in donor fluorescence lifetime further supports the FRET mechanism. Selectivity experiments confirmed the system's specificity for AFB1 detection, with a limit of detection (LOD) of 0.439 nM. These findings underscore the potential of FRET-based CQD systems for sensitive and selective AFB1 detection, highlighting their versatility in fluorescence-based sensing applications and their promise for rapid food safety monitoring.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}