Journal of Fluorescence最新文献

A Highly Selective Hemicyanine-Based Turn-Off Fluorescent Sensor for Cyanide Detection in Food Samples. 一种用于食品氰化物检测的高选择性半花青碱型关闭荧光传感器。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-08 DOI: 10.1007/s10895-026-04788-3

Fuat Gokbel, Ziya Aydin, Şeyma Akın, Esma Nur Çenet, Mustafa Keles

{"title":"A Highly Selective Hemicyanine-Based Turn-Off Fluorescent Sensor for Cyanide Detection in Food Samples.","authors":"Fuat Gokbel, Ziya Aydin, Şeyma Akın, Esma Nur Çenet, Mustafa Keles","doi":"10.1007/s10895-026-04788-3","DOIUrl":"https://doi.org/10.1007/s10895-026-04788-3","url":null,"abstract":"Cyanide is a highly toxic anion. Humans are commonly exposed to cyanide through the consumption of drinking water or by eating plants that contain cyanogenic glucosides, such as cassava, a key carbohydrate source in many diets. While numerous methods exist for cyanide detection, few are both cost-effective and simple enough for use by individuals without specialized training. In this work, we designed and synthesized a hemicyanine-based fluorescent sensor ZM-FES for the detection of cyanide (CN-). Among the anions tested, the sensor showed high selectivity towards CN-. The addition of CN- to ZM-FES in aqueous solution (ACN/H2O (1:1, v/v)) caused a dramatic decrease in the absorbance and fluorescence intensities. The detection mechanism was based on nucleophilic addition between CN- and the indolium group, which was confirmed by 1H NMR and mass spectral analysis. The fluorescence intensity plot as a function of CN- concentration showed a good linear relationship in the range 0-10 µM, and the detection limit was calculated as 0.195 µM. Furthermore, the proposed detection approach can operate over a wide pH range from 2.1 to 9.3. Finally, ZM-FES was successfully utilized to detect CN- in food samples and satisfactory results were obtained.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radical Quenching and LOX Inhibiting Properties of Indole Derivatives: A Plausible Mechanism of Action Through HAT, SET-PT and SPLET Pathway. 吲哚衍生物的自由基猝灭和LOX抑制特性：HAT、SET-PT和SPLET途径的作用机制

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-06 DOI: 10.1007/s10895-026-04783-8

Km Srishti, Oseen Negi, Anamika Gusain, Naresh Kumar, Rahul Kumar Vishwakarma, Prasanta Kumar Hota

{"title":"Radical Quenching and LOX Inhibiting Properties of Indole Derivatives: A Plausible Mechanism of Action Through HAT, SET-PT and SPLET Pathway.","authors":"Km Srishti, Oseen Negi, Anamika Gusain, Naresh Kumar, Rahul Kumar Vishwakarma, Prasanta Kumar Hota","doi":"10.1007/s10895-026-04783-8","DOIUrl":"https://doi.org/10.1007/s10895-026-04783-8","url":null,"abstract":"A series of 2-phenylindoles were synthesized and studied the radical quenching properties towards compounds with nitrogen radical. The present indoles exhibit radical quenching properties in a substituent dependent manner through proton and electron transfer mechanisms. ortho-Hydroxy-2-phenylindole and para-hydroxy-2-phenylindole show strong radical quenching properties towards DPPH radical as comparable to vitamin C, whereas meta-hydroxy-2-phenylindole and 2-phenylindole exhibit radical quenching properties with lower efficacy. All these indoles, however, exhibit efficient radical quenching properties towards ABTS radical as comparable to DPPH radical (IC50 towards DPPH/ABTS: 1: 335/22 µM, 2: 15/7 µM, 3: 102/8 µM, 4: 9/10 µM, vitamin C: 10/3 µM). These compounds also bind to lipoxygenase (LOX) and inhibit LOX activity with IC50 : 18-44 µM. It is shown that O-H bond dissociation energy and ionization energy play important role in deciding the radical quenching properties of present indole compound. The compound-LOX binding affinity and binding interface is computed through autodock vina. The indole-LOX binding interface comprises of hydrophobic amino acid residues. In the presence of. indole molecule, the radical quenching occurs through hydrogen atom and/or through electron and subsequently proton transfer mechanism.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fast-response Phosphorescence Sensor for Dissolved Oxygen Detection Based on PtOEP/TiO₂/CB@PFFE Sensing Film. 基于ptep /TiO2/CB@PFFE传感膜的溶解氧快速响应磷光传感器。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-05 DOI: 10.1007/s10895-026-04772-x

Jia Xiao, Minmin Han, Ting Li, Baohua Yue, Liuming Yan

{"title":"Fast-response Phosphorescence Sensor for Dissolved Oxygen Detection Based on PtOEP/TiO2/CB@PFFE Sensing Film.","authors":"Jia Xiao, Minmin Han, Ting Li, Baohua Yue, Liuming Yan","doi":"10.1007/s10895-026-04772-x","DOIUrl":"https://doi.org/10.1007/s10895-026-04772-x","url":null,"abstract":"A fast-response phosphorescence sensor for dissolved oxygen (DO) detection based on PtOEP/TiO2/CB@PFFE sensing film was developed. The DO sensing film features a tri-layer structure, comprising a sensing layer, a light-scattering layer, and a light-blocking layer. Fluorinated polymer PFFE as matrix was synthesized via free radical polymerization using 4-trifluoromethyl styrene (TFMST), 2,2,2-trifluoroethyl methacrylate (TFEMA) and 2-ethylhexyl acrylate (2-EHA) as monomers and 2,2-azobis(isobutyronitrile) (AIBN) as initiator. The sensing layer, light-scattering layer and light-blocking layer were fabricated by embedding platinum octaethylporphyrin (PtOEP), TiO2 and carbon black (CB) in PFFE, respectively. The addition of light-scattering layer and light-blocking layer enhances the phosphorescence intensity and phosphorescence lifetime of the PtOEP/TiO2/CB@PFFE sensing film, further improving the detection sensitivity of the sensor. The PtOEP/TiO2/CB@PFFE sensor demonstrated a response time of 30 s and a recovery time of 150 s and exhibited excellent reproducibility, reversibility and stability. The Stern-Volmer constant (KSV) of the Stern-Volmer curve was 0.4584 L/mg and the correlation coefficient (R) of the curve reached as high as 0.9993, indicating that the PtOEP/TiO2/CB@PFFE sensor exhibited high sensitivity for DO detection.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a Europium Molybdate Complex Luminescent Platform as a "Turn-off" Sensing Detection of Bilirubin: A Liver Function Biomarker. 钼酸铕配合物发光平台作为“关闭”传感检测胆红素的开发：一种肝功能生物标志物。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-05 DOI: 10.1007/s10895-026-04785-6

Ali Ibrahim Shkhair, Haitham K R Al-Sharifi, Sara Muneer Abbas

引用次数: 0

Rhodamine B-Modified Carbon Dots with EDTA Masking Strategy for Selective Detection of Cu²⁺. EDTA掩蔽策略修饰罗丹明b碳点选择性检测Cu 2 +

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-04 DOI: 10.1007/s10895-026-04784-7

Xiaoli Wu, Jiajia Du, Dandan Zhang, Jiayi Chen, Xi Yang, Xiaonan Liu

{"title":"Rhodamine B-Modified Carbon Dots with EDTA Masking Strategy for Selective Detection of Cu²⁺.","authors":"Xiaoli Wu, Jiajia Du, Dandan Zhang, Jiayi Chen, Xi Yang, Xiaonan Liu","doi":"10.1007/s10895-026-04784-7","DOIUrl":"https://doi.org/10.1007/s10895-026-04784-7","url":null,"abstract":"Iron(III) and copper(II) ions are ubiquitous in the environment, posing potential risks to the environment and human health, which urgently demands rapid detection methods. In this study, a ratiometric fluorescent probe was developed by integrating biomass-based carbon dots with rhodamine B (RhB) for the rapid and accurate detection of Fe³⁺ and Cu²⁺. Under normal conditions, the strong coordination ability of Fe³⁺ and Cu²⁺ enables them to rapidly occupy the active sites on the surface of carbon dots (CDs), resulting in rapid fluorescence changes. RhB provides a stable reference signal and achieves self-calibrated dual-emission output, thereby reducing matrix and environmental interferences. To address the coexistence of Fe³⁺ and Cu²⁺ in practical detection, ethylenediaminetetraacetic acid (EDTA) was introduced as a selective masking agent, which preferentially forms a stable complex with Fe³⁺. This reduces the signal interference of Fe³⁺ in low-concentration systems and realizes highly selective detection of Cu²⁺. In the detection of Cu²⁺ in actual water samples, the probe exhibits high sensitivity (4.91 µM) and favorable accuracy with recoveries ranging from 97.3% to 99.5%, demonstrating strong reliability in complex samples. This study not only provides a green and sensitive method for Cu²⁺ detection, but also presents an effective strategy for resolving specific detection issues in complex matrices using classical masking agents.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, Synthesis, and Characterization of TEPE-Zn-MOF as a Turn-On Fluorescent Probe for Pb²⁺ Detection. 用于pb2 +检测的TEPE-Zn-MOF荧光探针的设计、合成和表征

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-05-01 DOI: 10.1007/s10895-026-04770-z

Kinjal Modi, Dhruvi Kher, Bhavesh Dhumale, Nihal Patel, Keyur Bhatt, Chirag N Patel, Vaibhav Bhatt, Mukesh Chaudhari, Hitesh Patel, Hasit Vaghani, Krunal Modi, Sandeep Kumar, Disha Kothari

引用次数: 0

Green-Synthesized Chaenomeles speciosa-Derived Carbon Quantum Dots with Blue Fluorescence and Selective Pro-Apoptotic Effects in Cancer Cells. 绿色合成木瓜衍生的碳量子点在癌细胞中的蓝色荧光和选择性促凋亡作用。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-04-29 DOI: 10.1007/s10895-026-04771-y

Zeynep Betül Sarı, Abidin Gümrükçüoğlu, Emine İncilay Torunoğlu, Muhammet Emin Sarı, Erdi Can Aytar

{"title":"Green-Synthesized Chaenomeles speciosa-Derived Carbon Quantum Dots with Blue Fluorescence and Selective Pro-Apoptotic Effects in Cancer Cells.","authors":"Zeynep Betül Sarı, Abidin Gümrükçüoğlu, Emine İncilay Torunoğlu, Muhammet Emin Sarı, Erdi Can Aytar","doi":"10.1007/s10895-026-04771-y","DOIUrl":"https://doi.org/10.1007/s10895-026-04771-y","url":null,"abstract":"Carbon nanodots were synthesized from Chaenomeles speciosa flowers and comprehensively characterized. UV-Vis analysis revealed a broad absorption band from 200 to 400 nm, attributed to π→π* (200-250 nm) and n→π* (250-350 nm) transitions, while fluorescence under 365 nm excitation showed bright blue emission. HRTEM images indicated spherical nanoparticles forming clustered aggregates, with lattice fringes exhibiting interplanar spacings of 0.091-0.093 nm, confirming a partially graphitic structure. XRD analysis showed a broad amorphous baseline in the 10-40° 2θ range, indicating low crystallinity. FTIR and XPS analyses identified abundant surface -OH, C = O, and C-O groups, with elemental composition of C 68.28%, O 23.03%, N 6.70%, S 0.40%, and Si 1.59%, resulting in a C/O ratio of 2.97. Chaenomeles speciosa quantum dots (CS-CQDs) exhibited dose-dependent cytotoxicity in MDA-MB-231 cells (viability: 70% at 2.5 mg/mL, 60% at 5 mg/mL) and HeLa cells (approximately 50% at 2.5-5 mg/mL), with minimal effects on hTERT-HME1 cells (viability greater than 85% at 0.6 mg/mL). Apoptosis increased from 25% to 55% in MDA-MB-231, from 24% to 65% in HeLa, and from 5.9% to 25% in HME1, with negligible necrosis. Gene expression analyses showed NF-κB upregulation (3-fold in MDA-MB-231; 6-fold in HeLa), BAX and BCL-2 upregulation in HeLa (approximately 2.5-fold), and downregulation of HIF1A, IL-6, MMP2, and MMP9. Wound healing assays indicated reduced migration in MDA-MB-231 (44% to 21%), increased migration in HeLa (18.7% to 30%), and minimal change in HME1 (73.5% to 71.5%). These results demonstrate that CS-CQDs possess favorable optical and structural properties and selectively induce apoptosis in cancer cells, with minimal impact on non-cancerous cells, highlighting their potential as targeted anticancer nanomaterials.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cool White Light Emitting Dy³⁺ Activated Disodium Calcium Pyrophosphate Phosphor for WLEDs Application. 冷白光发光Dy3+活化焦磷酸钙二钠荧光粉的应用。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-04-29 DOI: 10.1007/s10895-026-04781-w

Umashankar Bhardwaj, Ganesh Ram Banjare, Chitrkant Belodhiya, D P Bisen, N Brahme, Sanjay Kumar Baghel, Vikas Kumar Jain, Vineet Kumar Shukla, Yugbodh Patle

{"title":"Cool White Light Emitting Dy3+ Activated Disodium Calcium Pyrophosphate Phosphor for WLEDs Application.","authors":"Umashankar Bhardwaj, Ganesh Ram Banjare, Chitrkant Belodhiya, D P Bisen, N Brahme, Sanjay Kumar Baghel, Vikas Kumar Jain, Vineet Kumar Shukla, Yugbodh Patle","doi":"10.1007/s10895-026-04781-w","DOIUrl":"https://doi.org/10.1007/s10895-026-04781-w","url":null,"abstract":"A series of Na₂CaP₂O₇: xDy3+ (x = 0.01-0.06) (abbreviated as NCPO) phosphors were synthesized using the solid-state reaction method in the present research work. X-ray diffraction (XRD) was used to confirm the phase purity and crystallinity of the synthesized phosphors. Morphological and elemental analyses were carried out using field emission scanning electron microscopy (FESEM) and energy-dispersive spectroscopy (EDS), respectively. Fourier transform infrared (FT-IR) spectroscopy assessed the functional groups, while diffuse reflectance spectroscopy (DRS) was employed to estimate the optical band gap. Photoluminescence (PL) spectroscopy was performed at an excitation wavelength of 351 nm to investigate the luminescence properties of the prepared phosphors. Two emission bands were subsequently observed at 485 nm and 575 nm, corresponding to 4F9/2 → 6H15/2 and 4F9/2 → 6H13/2 transitions, respectively. The critical distance (Rc) between Dy³⁺ ions in this host was calculated to be 17 Å, indicating that both nearest-neighbor ion interactions and dipole-dipole interactions were involved. The PL decay lifetime and internal quantum efficiency (IQE) of the synthesized phosphor are determined. Photometric studies reveal that the CIE coordinates fall very close to the white light region, and the CCT value is found to be greater than 5000 K, indicating that the prepared NCPO: Dy³⁺ phosphor is a promising candidate for cool WLEDs for outdoor lighting applications.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147773321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Optimization of a Glucose Fluorescence Nano-biosensor Based on Graft Copolymer of Poly(acrylic acid)-co-(vinyl phenyl boronic acid)-g-gelatin to Modify CdTe/TGA QDs. 基于聚丙烯酸-co-（乙烯基苯基硼酸）-g-明胶接枝共聚物修饰CdTe/TGA量子点的葡萄糖荧光纳米生物传感器设计与优化

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-04-29 DOI: 10.1007/s10895-026-04763-y

Ghasem Rezanejade Bardajee, Hamideh Elmizadeh, Leila Tayebi

{"title":"Design and Optimization of a Glucose Fluorescence Nano-biosensor Based on Graft Copolymer of Poly(acrylic acid)-co-(vinyl phenyl boronic acid)-g-gelatin to Modify CdTe/TGA QDs.","authors":"Ghasem Rezanejade Bardajee, Hamideh Elmizadeh, Leila Tayebi","doi":"10.1007/s10895-026-04763-y","DOIUrl":"https://doi.org/10.1007/s10895-026-04763-y","url":null,"abstract":"The design and fabrication of fluorescent nano-biosensors for detecting various analytes in complex matrices are of great interest to researchers. One of the interests of researchers in the medical field is the sensitive detection and measurement of glucose in biological fluids, as diabete is a chronic metabolic disease with a high risk of death in the world. In this work, a fluorescent nano-biosensor, based on modified cadmium telluride quantum dots capped with thioglycolic acid) CdTe/TGA QDs (with poly (acrylic acid)-co-(vinyl phenyl boronic acid) grafted onto gelatin, (CdTe-(PAA-co-VPB)-g-GE QDs), was fabricated for the detection of glucose in biological fluids. One of the components in the modified biopolymer coating is VPB, because it tends to cis-diol interactions with glucose. Therefore, the selectivity and sensitivity of the nano-biosensor are significantly increased. Then, its synthesis method was optimized for high fluorescence intensity with high sensitivity and stability using a 4-factor Box-Behnken statistical design. By adding different amounts of glucose to the nano-biosensor, its fluorescence emission is linearly quenched by a possible mechanism of Photo induced Electron Transfer )PET (. Also, the optimized nano-biosensor has very good repeatability and selectivity with a stability of 120 days. The detection limit of glucose is 20.26 ± 1.2 × 10- 9 mol L- 1, with a dynamic range from 2.26 ± 1.22 × 10- 7 to 1.11 ± 1.14 × 10- 3 mol L- 1. In addition, the prepared nano-biosensor is capable of measuring glucose in biological fluids with satisfactory results.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147773283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isoniazid-Derived Schiff Base Chemosensor for Dual-Mode Detection of Metal Ions and Bio-imaging Applications. 金属离子双模检测及生物成像应用的异烟肼衍生希夫碱化学传感器。

IF 3.1 4区化学

Journal of Fluorescence Pub Date : 2026-04-27 DOI: 10.1007/s10895-026-04774-9

Pooja Meena, Priyanka Surya, Ved Prakash Meena, Anita Kumari, Prabhat Ranjan, Sweta Singh, Ramhari Meena

引用次数: 0