Journal of Fluorescence最新文献

Development of a Charge-Mediated Disaggregation-Induced Fluorescence Enhancement Platform Using NS-Carbon Dots for Metformin Quantification and Pharmacokinetic Studies.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04170-9

Yousef A Bin Jardan, Mohamed M El-Wekil, Mohamed R Elmasry, Ashraf M Mahmoud, Al-Montaser Bellah H Ali

{"title":"Development of a Charge-Mediated Disaggregation-Induced Fluorescence Enhancement Platform Using NS-Carbon Dots for Metformin Quantification and Pharmacokinetic Studies.","authors":"Yousef A Bin Jardan, Mohamed M El-Wekil, Mohamed R Elmasry, Ashraf M Mahmoud, Al-Montaser Bellah H Ali","doi":"10.1007/s10895-025-04170-9","DOIUrl":"https://doi.org/10.1007/s10895-025-04170-9","url":null,"abstract":"A novel ratiometric fluorometric sensor has been developed utilizing dual-emission nitrogen and sulfur co-doped carbon dots (NS-CDs) for the sensitive determination of metformin. The sensing mechanism relies on a unique disaggregation phenomenon observed under acidic conditions, where electrostatic repulsion between positively charged NS-CDs and metformin molecules leads to enhanced fluorescence emission. Upon metformin addition, the NS-CDs exhibit differential enhancement of their characteristic emission peaks, with the 562 nm peak showing markedly greater amplification than the 365 nm peak. This distinctive response enabled the development of a ratiometric detection approach using the F562/F365 intensity ratio as an analytical signal, providing enhanced measurement reliability by minimizing biological matrix interferences. The sensor demonstrated excellent analytical performance with a linear response range of 0.05-0.9 µM and an impressive detection limit of 15 nM, surpassing the sensitivity of many previously reported methods. The method exhibited remarkable selectivity toward metformin in the presence of common interferents including co-administered drugs, biomolecules, and ionic species typically present in plasma samples. The practical utility of the sensor was validated through successful application in pharmacokinetic studies in rabbit plasma following oral metformin administration, demonstrating its potential for therapeutic drug monitoring and bioanalytical applications. This sensing platform combines high sensitivity, excellent selectivity, and rapid response time, making it a promising tool for metformin quantification in complex biological matrices.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacts of Excessive Iron Intake on Infant Growth and Fluorimetric and Colorimetric Detection Methods: A Comprehensive Review.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04183-4

Alaa Shafie, Amal Adnan Ashour, Faris J Tayeb, Mohammed Fareed Felemban

引用次数: 0

Development of Multifunctional C-dots from Processing Waste of Pomelo Fruits for Determination of pH and Methyl Parathion.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04137-w

Priya Darshini M J, A Sangeeta, Poonam Mishra

{"title":"Development of Multifunctional C-dots from Processing Waste of Pomelo Fruits for Determination of pH and Methyl Parathion.","authors":"Priya Darshini M J, A Sangeeta, Poonam Mishra","doi":"10.1007/s10895-025-04137-w","DOIUrl":"https://doi.org/10.1007/s10895-025-04137-w","url":null,"abstract":"Multifunctional fluorescent C-dots from Pomelo wastes (peel/pomace) were produced using microwave and hydrothermal treatment. Surface of synthesized C-dots were modified to detect the pesticide in food samples. Synthesized C-dots and functionalized C-dots were characterized using FTIR; SEM; and UV spectroscopy. Microwave synthesized C-dots were of amorphous structure and particle size were in the range of 0.4 to 2.5 nm. The surface passivated C-dots were used as a nanoprobe for cost-effective detection of methyl parathion in food samples; however C-dots without surface passivation were utilized sucessfully for the development of pH paper for determination of pH (3.5-12.5). Fluorescent intensity of developed pH paper varied linearly with the change in the pH. Utilizing optical characteristics and a large number of surface functional groups, C-dots have a potential to be used as a fluorescence or fluorescent sensor to detect methyl parathion from food samples by following the \"turn-on-off\" mechanism. LOD and LOQ level of surface passivated C-dots were 0.12 and 0.46 mg/L respectively for parathion methyl pesticide.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synergistic Fluorescence with Significant Red Shift in Coumarin-Doped PMMA Matrices Using CdTe Quantum Dots for Luminescent Concentrator 2D Position Sensing.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04153-w

Mohammed Alyami, Samah El-Bashir

{"title":"Synergistic Fluorescence with Significant Red Shift in Coumarin-Doped PMMA Matrices Using CdTe Quantum Dots for Luminescent Concentrator 2D Position Sensing.","authors":"Mohammed Alyami, Samah El-Bashir","doi":"10.1007/s10895-025-04153-w","DOIUrl":"https://doi.org/10.1007/s10895-025-04153-w","url":null,"abstract":"Luminescent concentrators (LCs) with dimensions of 15 × 10 × 0.3 cm were fabricated and calibrated as high-precision non-imaging position sensors for wide-area detecting applications. The plates were prepared using PMMA/chloroform solutions doped with 10⁻⁴ wt% coumarin dye (MACROLEX Fluorescent Red G) and varying concentrations of 3.5 nm CdTe quantum dots (QDs). Characterization techniques, including XRD, UV-vis absorption, and fluorescence polarization spectroscopy, revealed significant enhancements in photophysical properties with increasing CdTe QDs concentrations. At 0.8 wt%, a giant redshift of 58 nm and fluorescence quantum yield improvement from 90.05 to 94.76% were achieved. Fluorescence polarization measurements confirmed this concentration as optimal, with the highest fluorescence anisotropy. Preliminary evaluations of the proposed LC position sensors demonstrated excellent sensitivity (99.75%) across the horizontal (± 1 mm) and vertical (0-50 mm) displacement ranges in 10-micron increments. The obtained results endorsed the potential of luminescent concentrators as efficient position sensors, for achieving sustainable development goals regarding industrial growth and smart cities development.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuning the Chain Conformation of Pyrenyl-Pyridine Conjugated Oligomer Nanoprobe for Ultrasensitive Fluorescent Assaying of Fe³⁺ and Ascorbic Acid.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04158-5

Yaqian Zhao, Hailin Wang, Hongmei Huang, Mixue Chen, Yuqi Wen, Zisheng Xiao, Yi Xiao, Youyu Zhang, Xiaoxiao He, Kemin Wang

{"title":"Tuning the Chain Conformation of Pyrenyl-Pyridine Conjugated Oligomer Nanoprobe for Ultrasensitive Fluorescent Assaying of Fe3+ and Ascorbic Acid.","authors":"Yaqian Zhao, Hailin Wang, Hongmei Huang, Mixue Chen, Yuqi Wen, Zisheng Xiao, Yi Xiao, Youyu Zhang, Xiaoxiao He, Kemin Wang","doi":"10.1007/s10895-025-04158-5","DOIUrl":"https://doi.org/10.1007/s10895-025-04158-5","url":null,"abstract":"The chain conformation of conjugated oligomers are critical for constructing ultrafine fluorescent nanoprobes with outstanding sensing performances owing to their suitable molecular flexibility and fine-tuned aggregation state. Herein, a series of pyrenyl-pyridine oligomers (OPPs) were designed and conveniently prepared by one-pot Sonogashira coupling of flexible 2,6-bis(ethynyl)pyridine with different rigid pyrene unit. Novel fluorescent nanoprobes (OPPNPs, ca. 2.50-25.4 nm in diameter) were hence readily fabricated through a microemulsion route, showcasing significantly distinct detecting properties due to their distinctive chain conformations. In particular, ultrasmall OPP1NPs (~ 3.75 nm) bearing zig-zag-shaped 1,6-substituted pyrenyl-pyridyl conjugated chain presented superior π-π stacking, strong excimer emission and best sensing performances for Fe3+ via electron transfer (ET) and OPP1NPs aggregation-based fluorescence quenching. Additionally, ascorbic acid (AA) could act as an effective reducer and chelator, resulting in the fluorescence recovery of OPP1NPs. Under the optimal conditions, ultralow detection limits of OPP1NPs for Fe3+ (LOD, 0.06 nM, S/N = 3) and AA (LOD, 8 nM) were achieved. Furthermore, small and biocompatible OPP1NPs enabled efficient fluorescence imaging of Fe3+ and AA in live cells. Moreover, the conformation-regulated sensing strategy and ET mechanism are also supported by DFT calculations.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative Cerium and Chromium Co-doped Carbon Quantum Dots: Synthesis, Smartphone-Compatible and Sensitive Fluorescence Approach for Detection of Vitamin B₁₂.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04165-6

Bindu Dhuva, Sangeeta Obrai

{"title":"Innovative Cerium and Chromium Co-doped Carbon Quantum Dots: Synthesis, Smartphone-Compatible and Sensitive Fluorescence Approach for Detection of Vitamin B12.","authors":"Bindu Dhuva, Sangeeta Obrai","doi":"10.1007/s10895-025-04165-6","DOIUrl":"https://doi.org/10.1007/s10895-025-04165-6","url":null,"abstract":"Carbon quantum dots (CQDs) have acquired significant attention recently due to their unique properties and wide-ranging applications. These nanoscale carbon-based materials exhibit exceptional photoluminescence, excellent biocompatibility, and remarkable chemical stability, making them promising candidates for various technological advancements. The present study describes novel heteroatom co-doped carbon quantum dots as sensors to probe VitB12 biomolecules in an aqueous solution by employing sensitive and straightforward fluorescence quenching measurements. The designed CQDs were characterised with UV-Vis absorption spectroscopy, FT-IR, XRD, HR-TEM, SEM, EDS, XPS, TCS-PC and fluorescence spectroscopy. The current work aims to modify size distribution and heteroatom doping to create cerium and chromium co-doped CQDs (Ce/Cr-CQDs) with improved sensing capabilities. One-step hydrothermal calcination was used to generate cerium and chromium co-doped carbon quantum dots (Ce/Cr-CQDs), which were then investigated as sensing biomolecules for biological applications. The correlation coefficient(R2) and limit of detection (LOD) were 0.993 and 1.88 µM, respectively, for VitB12 over a concentration range of 3 µM to 50 µM. Real sample analyses were performed with mean recoveries ranging from 97.5 to 99% of physiologically relevant VitB12 for developing Ce/Cr-CQDs based fluorescence sensors/probes. The significant and observable color variations of the CQDs have been effectively coupled to the smartphone app \"RGB color detector,\" and promising results were reproduced.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescence Enhanced Water-Soluble Ruthenium Complex: Advancing Precision in Cr(VI) Detection and Quantification.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-13 DOI: 10.1007/s10895-025-04150-z

Pooja Rajagopalan, Sowmiya Saravanan, Mohan Ranganathan, Kalarical Janardhanan Sreeram, Sathyaraj Gopal

{"title":"Fluorescence Enhanced Water-Soluble Ruthenium Complex: Advancing Precision in Cr(VI) Detection and Quantification.","authors":"Pooja Rajagopalan, Sowmiya Saravanan, Mohan Ranganathan, Kalarical Janardhanan Sreeram, Sathyaraj Gopal","doi":"10.1007/s10895-025-04150-z","DOIUrl":"https://doi.org/10.1007/s10895-025-04150-z","url":null,"abstract":"The environment and human health are both at risk from the heavy metal chromium (VI), which is extremely toxic and carcinogenic. Chromium (VI) in various matrices must be accurately and quickly detected for both public safety and regulatory compliance. This paper describes the design and development of a novel fluorescence detector suitable for the sensitive and selective quantification of chromium (VI) ions. Utilizing the special qualities of a properly selected fluorophore with high sensitivity and selectivity toward chromium (VI), the suggested ruthenium metal-based fluorescence detector makes use of these advantages. Ruthenium (II) complex of composition [Ru(bpy)2(PhDORi)]Cl2 bpy 2,2'-bipyridine, PhDORi (2S,3R)-4-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)-butane-1,2,3-triol was synthesized. Characterizing the produced chemical has involved analytical and spectroscopic approaches. This complex displayed a broad metal-to-ligand charge transfer band at ~ 457 nm in aqueous solution. Ru(II) complex undergo relatively reversible one-electron oxidation and reduction involving the Ru(II)/Ru(III), according to cyclic voltammetry investigations. In an aqueous solution, the complex exhibits intense fluorescence when the molecule is excited at the MLCT band. The complex exhibit selectivity towards chromate/dichromate anions in the aqueous solution. With ppm to ppb concentration and a linear response across a 105fold concentration range, concentration-dependent emission quenching of the fluorophore by the chromate ions was shown.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hybrid Materials Based on Reduced Graphene Oxide; Synthesis and Characterization of V and Ru Metal Complexes.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-12 DOI: 10.1007/s10895-025-04184-3

Mustafa Bal, Mehmet İsa Tontuş, Mehmet Tümer

引用次数: 0

Rationally Designed Maleimide Dyes for Large Stokes Shifted Solvatochromism and Aggregation-Induced Emission.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-11 DOI: 10.1007/s10895-025-04172-7

Kirankumar S Gosavi, Aniket Patil, Gopal Wagh, Gunvant H Sonawane, Abhishek Panigrahi, Deepak, Kaushik Pal

引用次数: 0

A Mini Review on Carbazole Fluoroscent Chemosensors for the Detection of Cu (II) Ion: A Comprehensive Review.

IF 2.6 4区化学

Journal of Fluorescence Pub Date : 2025-02-11 DOI: 10.1007/s10895-024-04079-9

Qasim Ullah, Aram Rahman, Mohammad Arifuddin, Ira Khan, Nizamul Haque Ansari, Pathan Arif Ali Khan

{"title":"A Mini Review on Carbazole Fluoroscent Chemosensors for the Detection of Cu (II) Ion: A Comprehensive Review.","authors":"Qasim Ullah, Aram Rahman, Mohammad Arifuddin, Ira Khan, Nizamul Haque Ansari, Pathan Arif Ali Khan","doi":"10.1007/s10895-024-04079-9","DOIUrl":"https://doi.org/10.1007/s10895-024-04079-9","url":null,"abstract":"The first fluorescent chemosensor was introduced by F. Goppelsröder (1867) for the detection of Al (III) ion through the formation of strongly fluorescent chelate of morin ion. This mini review focuses on carbazole derivatives fluorescence for detecting Cu2+ ions in aqueous and living systems. Carbazole is an example of heterocyclic compound containing nitrogen atom. Carbazole and its derivatives have been used as fluorescent sensors for the detection of Cu2+ ions due to the some inherent features such as high solubility, presence of large conjugated system, active intramolecular charge transfer capability, reasonable thermal resistance, photochemical useful, photoelectric properties, and bioactive efficiencies. These features make carbazole and its derivatives effective for applications in fluorescent sensing, photoelectric devices, dyes, molecular recognition, and pharmaceuticals. Different photophysical mechanisms such as chelation enhanced fluorescence (CHEF), intramolecular charge transfer (ICT), photoinduced electron transfer (PET), aggregation induced emission (AIE) play important role in the detection of Cu2+ ions while using fluorescent sensors. This review also highlighted on various methods of synthesis of carbazole in brief. The work done on the applications of carbazole fluorescent during the period 2013 to till date has been summarized in tabular form.","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0