Journal of Environmental Sciences-china最新文献

{"title":"Single and combined impacts of antibiotics on aerobic denitrification: Cell growth characteristics and functional genes expressions","authors":"Rong-Rong Chang ,&nbsp;Chang-Ze Shi ,&nbsp;Yun-Jie Ruan ,&nbsp;Bao-Cheng Huang ,&nbsp;Ren-Cun Jin ,&nbsp;Ming Dong ,&nbsp;Wen-Bing Li","doi":"10.1016/j.jes.2025.04.037","DOIUrl":"10.1016/j.jes.2025.04.037","url":null,"abstract":"<div><div>Antibiotic contamination has garnered significant attention, particularly given the growing pressures from aquaculture, a key contributor to environmental antibiotic loads. Addressing both antibiotic and nitrogen pollution in such ecosystems is critical. In this study, the aerobic denitrifying bacterium <em>Marinobacter hydrocarbonoclasticus</em> RAD-2, previously isolated in our laboratory, was subjected to a series of concentration gradients (0, 20, 40, 60, 80, 100 mg/L) to evaluate the single and combined effects of tetracycline (TET) and chlortetracycline (CTC) on the aerobic denitrification process. Among them, the combined effects of antibiotics were set up in a full-factor experimental design (a total of 30 treatment combinations) on the basis of the single-factor experiments of TET and CTC. Results demonstrated that the inhibitory impact of both antibiotics intensified with increasing concentration, with CTC exerting a more pronounced inhibitory effect. Notably, RAD-2 was unable to proliferate at 100 mg/L of TET or 80 mg/L of CTC. High concentrations of either antibiotic significantly suppressed the expression of key denitrification functional genes, including <em>nirX, napA, norB</em>, and <em>nosZ</em>. Furthermore, simultaneous exposure to both antibiotics led to a rapid decline in nitrogen removal efficiency (TET or CTC &gt; 60 mg/L), alongside substantial inhibition of bacterial growth and functional gene expression, except for <em>napA</em>. Under specific concentration ranges, the combination of TET and CTC exhibits a certain degree of antagonistic effect. These findings provide critical insights into the restoration of wetland ecosystem health and inform strategies to mitigate the dual challenges of antibiotic and nitrogen pollution in aquaculture effluents.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 461-467"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile preparation of hierarchical porous MOF-based hollow carbon nanofiber mats using a polymer-blend electrospinning strategy for efficient adsorption of ciprofloxacin","authors":"Shuai Dou ,&nbsp;Qi-Jun Zhang ,&nbsp;Peng Wu ,&nbsp;Hui-Wen Huo ,&nbsp;Lu-Bin Zhong ,&nbsp;Yu-Ming Zheng","doi":"10.1016/j.jes.2025.04.029","DOIUrl":"10.1016/j.jes.2025.04.029","url":null,"abstract":"<div><div>A novel hierarchical porous metal-organic framework (MOF)-based hollow carbon nanofiber mat (CNFM) was prepared through a facile electrospinning process followed by carbonization. Two immiscible polymers, polyacrylonitrile/polymethyl methacrylate (PAN/PMMA), and porous zeolitic imidazolate framework-8 (ZIF-8) particles were selected as components for the electrospinning suspension. The resulting PPZ-CNFM-1–2–2 (PAN:PMMA:ZIF-8 = 1:2:2, mass ratio) exhibited a hollow tubular structure with uniformly distributed dense hollow-spheres on the tube walls. The obtained CNFM possessed a high Brunauer-Emmett-Teller specific surface area (<em>S</em>_BET) of 1696 m²/g and total pore volume of 2.74 cm³/g, which are comparable to those achieved by traditional physical or chemical activation methods. This MOF-based CNFM demonstrated excellent adsorption performance towards ciprofloxacin (CIP), exhibiting a high static adsorption capacity of approximately 600 mg/g and achieving adsorption equilibrium withing only 1 h. The exceptional adsorption capacity can be attributed to its high <em>S</em>_BET and abundant pores that accommodate CIP molecules, while the rapid adsorption rate is facilitated by the presence of hollow-sphere and hollow tubular structures in the carbon nanofibers. Furthermore, the study revealed the significant contributions of pore-filling effect during the adsorption process. Fixed-bed experiments confirmed that this MOF-based hollow CNFM holds great potential for large-scale applications in purifying CIP-contaminated water.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 241-252"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of conventional municipal wastewater treatment plants in microplastics removal: Insights from multiple analytical techniques","authors":"Simone Cavazzoli ,&nbsp;Costanza Scopetani ,&nbsp;David Chelazzi ,&nbsp;Tania Martellini ,&nbsp;Alessandra Cincinelli ,&nbsp;Emiliano Carretti ,&nbsp;Miriam Ascolese ,&nbsp;Riccardo Gori ,&nbsp;Karl Mair ,&nbsp;Werner Tirler ,&nbsp;Massimo Donegà ,&nbsp;Gianni Andreottola","doi":"10.1016/j.jes.2025.04.035","DOIUrl":"10.1016/j.jes.2025.04.035","url":null,"abstract":"<div><div>This study investigated microplastics (MPs) sized 10–5000 µm across stages of a conventional municipal wastewater treatment plant using multiple analytical techniques. Samples were collected via pumping and filtration, treated with the Fenton reaction for wet peroxidation, and separated by density separation. Analysis employed Focal Plane Array Micro-Fourier Transform Infrared Spectroscopy (FPA micro-FTIR), a widely used technique in MPs analysis, alongside the less common Laser Direct Infrared Spectroscopy (LDIR), providing complementary data on particle composition, shape, size, and colour. To enhance insights, spectroscopic methods were supplemented with Thermal Desorption Gas Chromatography-Mass Spectrometry (TD-GC/MS), calibrated for specific polymers, to quantify MPs by mass and assess removal efficiency. Wastewater treatment effectively reduced MPs. In influent samples, concentrations reached 72 MPs/L (FTIR), 2117 MPs/L (LDIR), and 177 µg/L (TD-GC/MS). Primary treatments removed 41 %–55 %, while the wastewater treatment plant effluent contained 1 MPs/L (FTIR), 93 MPs/L (LDIR), and 2 µg/L (TD-GC/MS), reflecting 96 %–99 % removal efficiency. Activated sludge showed concentrations of 123 MPs/L (FTIR), 10,800 MPs/L (LDIR), and 0.3 mg/g dry weight (TD-GC/MS), underscoring its role in MPs capture. However, sludge dewatering released significant MPs into centrifuge rejected water: 484 MPs/L (FTIR), 23,000 MPs/L (LDIR), and 1100 µg/L (TD-GC/MS). These results highlight the effectiveness of conventional treatments in MPs removal and the critical role of sludge in capturing these contaminants. However, sludge dewatering poses a risk of reintroducing MPs into the environment. Effective sludge management should prioritize nutrient recovery and biomass valorisation to mitigate these risks and minimise harmful environmental impacts.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 424-438"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing heavy metal pollution in urban children’s playgrounds: Comparative analysis of soil, dust, and moss bioaccumulation","authors":"Kaan Isinkaralar ,&nbsp;Paweł Świsłowski ,&nbsp;Oznur Isinkaralar ,&nbsp;Małgorzata Rajfur ,&nbsp;Tuyet Nam Thi Nguyen ,&nbsp;Anna Di Palma ,&nbsp;Sneha Gautam","doi":"10.1016/j.jes.2025.04.031","DOIUrl":"10.1016/j.jes.2025.04.031","url":null,"abstract":"<div><div>Toxic heavy metals are ubiquitous environmental contaminants that can detrimentally influence human well-being, especially in the pediatric population. This study investigated soil, dust, and moss contamination collected from six urban children’s playground (parks 1 to 6) in Çankaya District with heavy metals (Cr, Cu, Cd, Ni, Pb, and Zn). The highest values of Cu (44.1 mg/kg), Ni (45.6 mg/kg), and Pb (44.2 mg/kg) were recorded from park dust. Moss samples showed higher values of Cr and Zn, respectively, as 68.7 mg/kg and 284.3 mg/kg. Of these, surface soil presented the lowest concentrations, with Zn showing the highest concentration at 259 mg/kg and Cd the lowest at 1.9 mg/kg. Moss showed the highest total metal load Σ=482.1 mg/kg, followed by dust Σ = 457.9 mg/kg and soil Σ =3 88.3 mg/kg. Significant differences of <em>p</em> &lt; 0.05 between the soil and other sample types, together with a strong correlation of <em>R</em>² = 0.9443, may indicate that moss metal concentration is influenced by natural and anthropogenic sources by wet or dry deposition. Spatial analysis revealed metal hotspots near roadways, with Cr and Cu less concentrated in traffic areas. Significant variability was noted across parks, far from vehicular traffic and polluting land uses (parks 1 and 2), showing lower concentrations. Principal component analysis (PCA) and positive matrix factorization (PMF) identified four emission sources: diesel combustion, transportation, and fossil fuel combustion, which are transported up to several kilometers away from their sources and transferred to the soil by atmospheric deposition. Enrichment and bioaccumulation factors highlighted high Cd enrichment in dust, with significant bioaccumulation in mosses. Pollution index values varied, with parks under the pressure of vehicular traffic, commercial and industrial zones (park 6) showing the highest contamination. These local findings draw attention to the striking impact of land use decisions at a lower scale on the health risks of humans, especially children.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 700-712"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the origins of Northern Thailand’s haze: comprehensive chemical characterization and source apportionment of PM2.5 using targeted molecular markers","authors":"Supattarachai Saksakulkrai ,&nbsp;Somporn Chantara ,&nbsp;Pavidarin Kraisitnitikul ,&nbsp;Deepchandra Srivastava ,&nbsp;Zongbo Shi","doi":"10.1016/j.jes.2025.04.040","DOIUrl":"10.1016/j.jes.2025.04.040","url":null,"abstract":"<div><div>Annual haze in Northern Thailand has become increasingly severe, impacting health and the environment. However, the sources of the haze remain poorly quantified due to limited observational data on aerosol molecular tracers. This study comprehensively investigates chemical composition of PM_2.5, including both inorganic and organic compounds throughout haze and post-haze periods in 2019 at a rural site of Northern Thailand. Average PM_2.5 concentrations during haze and post-haze period were 87 ± 36 and 21 ± 11 µg/m³, respectively. Organic matter was the dominant contributor in PM_2.5 mass, followed by water soluble inorganic ions and mineral dust. Molecular markers, including levoglucosan, dehydroabietic acid, and 4-nitrocatechol, and ions (Cl^-, and K⁺), were used to characterize low haze (PM_2.5 &lt; 100 µg/m³) and episodic haze (PM_2.5 &gt; 100 µg/m³). Low haze is associated with local aerosols from agricultural waste burning, while episodic haze is linked to aged aerosols from mixed agricultural waste, softwood, and hardwood burning. Source apportionment incorporating these molecular markers in receptor modelling (Positive matrix factorization), identified three distinct biomass burning sources: mixed, local, and aged biomass burnings, contributing 31, 19 and 13 % of PM_2.5 during haze period. During post-haze period, contributions shifted, with local biomass burning (32 %) comparable to secondary sulfate (34 %) and mixed dust and traffic sources (26 %). These findings demonstrate that both regional and local sources contribute to severe haze, highlighting the need for integrated policies for cross-border cooperation as well as stricter regulations to reduce biomass burning in Northern Thailand and Southeast Asia.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"159 ","pages":"Pages 635-648"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decomposing riverine nitrogen and phosphorus fluxes into different frequency classes along the Yangtze River, China","authors":"Wei Gao ,&nbsp;Zhongzhao Duan","doi":"10.1016/j.jes.2025.04.027","DOIUrl":"10.1016/j.jes.2025.04.027","url":null,"abstract":"<div><div>Enhanced riverine nitrogen (N) and phosphorus (P) exports from anthropogenic activities have substantially increased primary productivity in downstream waters and induced harmful ecosystem effects. The components of riverine nutrient fluxes determine environmental responses that remain largely unknown. We identified different components of riverine N and P exports based on a load-hydrograph analysis of multiple sections of the Yangtze River in China based on long-term daily nutrient fluxes. Our results indicate that the increasing trend of riverine N and P fluxes from upstream to downstream can be reversed by the retention effect of dams and lakes, which is more significant for total phosphorus and its high-flux component than total nitrogen. The greatest nutrient retention along the river was mainly attributed to the Three Gorges Dam, which has a significant retention effect on both N and P fluxes, particularly on the high flux and TP. While high nutrient fluxes dominate upstream, middle and low fluxes dominate downstream. Significant but uncommon trends were observed for all nutrient flux components along the river. While both, medium and low flux percentages increase significantly, those of high flux decrease. The net change of N and P fluxes along the Yangtze River do not coincide in space, indicating heterogeneity between the river’s source and sink of N and P. Knowledge of the inconsistent alteration of riverine nutrient flux and its components should facilitate efforts to make better measures to mitigate nutrient-related problems in the Yangtze River.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 344-354"},"PeriodicalIF":6.3,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metagenomic investigations of microbial community response and antibiotic resistance genes in river sediments polluted by perfluoroalkyl acids","authors":"Nannan Lu ,&nbsp;Zhenqi Du ,&nbsp;Guixue Feng ,&nbsp;Xiaodong Xin ,&nbsp;Minghai Che ,&nbsp;Ruibao Jia ,&nbsp;Wenhai Chu","doi":"10.1016/j.jes.2025.04.024","DOIUrl":"10.1016/j.jes.2025.04.024","url":null,"abstract":"<div><div>Liquid-solid phase transfer promotes the interaction of perfluoroalkyl acids (PFAAs) with the microbial system of river sediments, which may affect the environmental behavior of antibiotic resistance genes (ARGs) contained in benthic environments. Sediments collected from the receiving water of the largest fluoropolymer production facility in China were analyzed to investigate the impact of PFAAs on microbial communities and ARG profiles. The main contributors to the PFAAs were perfluorooctanoic acid and perfluorobutanoic acid, whose proportions (86.9 %-93.4 %) in the downstream surface sediments affected by industrial effluents were significantly higher than in the corresponding upstream samples (53.3 %). A reduction in microbial diversity and richness was observed in the presence of high concentrations of PFAAs at the downstream sites. 144 ARG subtypes, including three high-risk subtypes (<em>bacA, aac (6′)-I</em> and <em>aadA</em>), were identified in sediment samples. The discharge of fluorochemical effluents also results in a reduction of ARG diversity at subtype level. PFAAs exert a pronounced influence on the profile of ARGs in sediment. PFAAs and water quality parameters (e.g. pH and total phosphorus) were key drivers of the microbial community composition in the sediment. The regulation of microbial communities by PFAAs may represent an important pathway by which these compounds affect ARG profiles.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 300-307"},"PeriodicalIF":6.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying the contribution of reactive nitrogen loss through anaerobic ammonium oxidation in global wetlands and oxygen minimum zones","authors":"Bangrui Lan ,&nbsp;Shuci Liu ,&nbsp;Shanyun Wang ,&nbsp;Yanting Zhang ,&nbsp;Longbin Yu ,&nbsp;Chunlei Liu ,&nbsp;Guibing Zhu","doi":"10.1016/j.jes.2025.04.021","DOIUrl":"10.1016/j.jes.2025.04.021","url":null,"abstract":"<div><div>Anaerobic ammonium oxidation (anammox) plays a vital role in the global nitrogen cycle by mitigating reactive nitrogen. In recent years, its ecological importance has drawn increasing attention. Despite its widespread occurrence, the distribution and quantitative contribution of anammox to global nitrogen loss remain unclear. We collected 390 reported anammox activity measurements which were obtained using ¹⁵N isotope tracing techniques and analyzed anammox rate and environmental factors including soil/sediment and water property using generalized additive models (GAMs). Moreover, based on the division of the anammox activity region, we estimated anammox-driven nitrogen loss across different ecosystems including wetlands and oxygen minimum zones (OMZs) ecosystems. Our findings revealed that soil moisture content was the most significant predictor of anammox activity in wetlands ecosystems. Paddy fields contributed 51 % of anammox-driven nitrogen loss (32.0 Tg N/yr), followed by rivers/lakes (29 %) and wetlands (20 %). Asia emerged as the dominant region for anammox-driven nitrogen loss (30.7 Tg N/yr), with paddy fields making a substantial contribution. North America was the second-largest contributor (25.4 Tg N/yr), with rivers/lakes being the main sources of nitrogen loss. In OMZs ecosystems, nitrate and dissolved oxygen were key factors influencing anammox rates. OMZs were hotspots for anammox, with peak activity at 300 m depth and nitrogen loss totaling 68.6 Tg N/yr, mostly between 100 and 500 m depths. This study underscores the critical role of anammox in global nitrogen cycling and offers a basis for environmental nitrogen management through predictive anammox modeling.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 355-363"},"PeriodicalIF":6.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogeography and diversity of wetland soils bacterial communities across temperature zones based on independent studies","authors":"Lei Zheng,&nbsp;Qi Tian,&nbsp;Qiuyang Tan,&nbsp;Xue Wang,&nbsp;Yuzi Xing,&nbsp;Yaoxin Zhang","doi":"10.1016/j.jes.2025.04.025","DOIUrl":"10.1016/j.jes.2025.04.025","url":null,"abstract":"<div><div>Wetlands are vital ecosystems that perform essential functions such as climate regulation, environmental purification, material circulation and energy flow. They play an essential role in global biogeochemical cycles, driven primarily by microorganisms. Understanding the distribution of wetland microorganisms across different temperature zones is key to comprehending their ecological roles. A meta-analysis of 704 wetland soil samples on microbial communities was conducted, using statistical methods like analysis of variance, principal component analysis, non-metric nultidimensional scaling, and structural equation modeling to examine biogeography and diversity across temperature zones. Our findings revealed a clear latitudinal diversity gradient pattern, with the highest microbial abundance in the tropics and the lowest in the southern temperate zone, which differed significantly from other temperature zones. Proteobacteria (37.76 %-51.04 %), Acidobacteria (5.11 %-30.70 %) and Bacteroidetes (3.43 %-16.16 %) dominanted the bacterial communities. Notably, the southern temperate zone showed significant variations, with a higher prevalence of Acidobacteria (30.07 %). To investigate the causes of this variability, we screened 177 core microbiome and identified latitude as the core environmental factor influencing microbial community composition. Moreover, soil microorganisms exhibited strong nitrogen cycling potentials (particularly <em>nirD</em> and <em>nirB</em>) and carbon cycling potentials (especially <em>accA</em>), with gene abundances showing little variation across temperature zones. Wetland bacterial communities also demonstrated high stability, with average variation degree index values ranging from 0.1 to 0.3. Our results improve the understanding of the diversity and biogeographic mechanisms of wetland bacterial communities and hold significant implications for the management and conservation of wetlands.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"160 ","pages":"Pages 439-449"},"PeriodicalIF":6.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145154436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of indoor airborne microbiome with systemic inflammation in the context of indoor particulate matter pollution and the metabolic mechanisms","authors":"Yetong Zhao ,&nbsp;Luyi Li ,&nbsp;Wenlou Zhang ,&nbsp;Shan Liu ,&nbsp;Wanzhou Wang ,&nbsp;Xuezhao Ji ,&nbsp;Di Yang ,&nbsp;Lifang Zhao ,&nbsp;Zhihong Zhang ,&nbsp;Xinbiao Guo ,&nbsp;Furong Deng","doi":"10.1016/j.jes.2025.04.022","DOIUrl":"10.1016/j.jes.2025.04.022","url":null,"abstract":"<div><div>Microorganisms constitute an essential component in the indoor environment, which is closely related to human health. However, there is limited evidence regarding the associations between indoor airborne microbiome and systemic inflammation, as well as whether this association is modified by indoor particulate matter and the underlying mechanisms. In this prospective repeated-measure study among 66 participants, indoor airborne microbiome was characterized using amplicon sequencing and qPCR. Indoor fine particulate matter (PM_2.5) and inhalable particulate matter (PM₁₀) were measured. Systemic inflammatory biomarkers were assessed, including white blood cell (WBC), neutrophil (NEUT), monocyte, eosinophil counts, and their proportions. Targeted serum amino acid metabolomics were conducted to explore the underlying mechanisms. Linear mixed-effect models revealed that bacterial and fungal Simpson diversity were significantly associated with decreased WBC and NEUT. For example, for each interquartile range increase in the bacterial Simpson diversity, WBC and NEUT changed by -4.53 % (95 % CI: -8.25 %, -0.66 %) and -5.95 % (95 % CI: -11.3 %, -0.27 %), respectively. Notably, increased inflammatory risks of airborne microbial exposure were observed when indoor PM_2.5 and PM₁₀ levels were below the WHO air quality guidelines. Mediation analyses indicated that dopamine metabolism partially mediated the anti-inflammatory effects of fungal diversity exposure. Overall, our study indicated protection from a diverse indoor microbial environment on cardiovascular health and proposed an underlying mechanism through amino acid metabolism. Additionally, health risks associated with microbial exposure deserve more attention in contexts of low indoor particulate matter pollution. Further research is necessary to fully disentangle the complex relationships between indoor microbiome, air pollutants, and human health.</div></div>","PeriodicalId":15788,"journal":{"name":"Journal of Environmental Sciences-china","volume":"159 ","pages":"Pages 187-198"},"PeriodicalIF":6.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}