Journal of Exercise Rehabilitation最新文献

筛选
英文 中文
Postnatal treadmill exercise alleviates cognitive deficits in offspring exposed to gestational diabetes mellitus via reactivation of the hippocampal Wnt/β-catenin signaling pathway. 产后跑步机运动通过海马Wnt/β-catenin信号通路的再激活减轻妊娠糖尿病后代的认知缺陷。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-02-23 eCollection Date: 2026-02-01 DOI: 10.12965/jer.2550884.442
Kyung-Wan Baek, Jong-Hwa Won, Sam-Jun Lee
{"title":"Postnatal treadmill exercise alleviates cognitive deficits in offspring exposed to gestational diabetes mellitus via reactivation of the hippocampal Wnt/β-catenin signaling pathway.","authors":"Kyung-Wan Baek, Jong-Hwa Won, Sam-Jun Lee","doi":"10.12965/jer.2550884.442","DOIUrl":"10.12965/jer.2550884.442","url":null,"abstract":"<p><p>Gestational diabetes mellitus (GDM) exposes the developing fetal brain to hyperglycemia and has been linked to adverse neurocognitive outcomes in offspring; however, effective postnatal strategies and underlying mechanisms remain incompletely defined. Here, we tested whether early-life aerobic exercise rescues hippocampus-dependent memory impairment and canonical Wnt/β-catenin signaling deficits in offspring born to dams with streptozotocin-induced GDM. Pregnant C57BL/6 mice received streptozotocin (40 mg/kg, gestational day 7) or saline. Male offspring were weaned and assigned to sedentary control or treadmill exercise (15 m/min, 60 min/day, 5 days/wk, 2 weeks), generating four groups: saline control (Sal-CON, n=12), saline exercise (Sal-Ex, n=12), GDM control (GDM-CON, n=12), and GDM exercise (GDM-Ex, n=12). Spatial learning and reference memory were assessed using the Morris water maze, and spatial working memory was evaluated with a T-maze task. Hippocampal expression of Wnt3, β-catenin, and glycogen synthase kinase-3β (GSK-3β) was quantified by Western blotting. GDM offspring exhibited impaired hippocampal memory performance, evidenced by a reduced hidden-to-visible platform latency ratio in the Morris water maze and loss of novelty preference in the T-maze. These behavioral deficits were accompanied by suppression of canonical Wnt signaling, with decreased hippocampal Wnt3 and β-catenin and increased GSK-3β in GDM-CON compared with controls. Notably, postnatal treadmill exercise significantly improved both reference and working memory and normalized Wnt/β-catenin pathway components in GDM offspring. Collectively, these findings indicate that early-life aerobic exercise mitigates GDM-associated cognitive vulnerability, at least in part, by reactivating hippocampal Wnt/β-catenin signaling.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 1","pages":"22-30"},"PeriodicalIF":1.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is the monetary value of a single scientific paper? 一篇科学论文的货币价值是多少?
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-02-23 eCollection Date: 2026-02-01 DOI: 10.12965/jer.2550818.409
Yong-Seok Jee
{"title":"What is the monetary value of a single scientific paper?","authors":"Yong-Seok Jee","doi":"10.12965/jer.2550818.409","DOIUrl":"10.12965/jer.2550818.409","url":null,"abstract":"","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 1","pages":"1-2"},"PeriodicalIF":1.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of motion recognition-based interactive training content to enhance motor functions in older adults. 基于动作识别的交互式训练内容的开发,以增强老年人的运动功能。
IF 1.9
Journal of Exercise Rehabilitation Pub Date : 2026-02-23 eCollection Date: 2026-02-01 DOI: 10.12965/jer.2550892.446
Yun-Hee Sung
{"title":"Development of motion recognition-based interactive training content to enhance motor functions in older adults.","authors":"Yun-Hee Sung","doi":"10.12965/jer.2550892.446","DOIUrl":"10.12965/jer.2550892.446","url":null,"abstract":"<p><p>The global aging population is rapidly increasing, with associated declines in motor and cognitive function leading to higher fall risk and reduced independence. Exercise interventions improve strength, balance, and cognition, but accessibility barriers remain. While technology assistance programs are promising, they often lack clinical perspectives, are difficult to adapt, and lack features that encourage participation. This study aimed to develop and evaluate a motion recognition-based interactive training program designed by a physical therapist to enhance motor function and physical fitness in older adults. Twenty-eight community-dwelling older adults (≥65 years) were randomly assigned to an experimental group (n=13) or control group (n=15). The experimental group completed three weekly sessions of motion recognition exercises with adaptive feedback for 4 weeks, while the control group performed stretching. Outcomes included task performance metrics (attempts, corrections, accuracy) automatically recorded by the program and fitness measures from the senior fitness test. The experimental group showed significant increases in attempts and corrections across all body parts, with notable accuracy improvement in head movements (<i>P</i><0.05). Flexibility significantly improved between groups, while both groups improved in lower extremity strength and endurance. No significant changes were observed in upper limb strength or agility. A clinically designed, motion recognition-based interactive program enhanced motor performance and flexibility in older adults. Incorporating adaptive difficulty and real-time feedback, it shows potential as a scalable, cost-effective digital intervention for promoting active aging.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"22 1","pages":"31-37"},"PeriodicalIF":1.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of regular treadmill exercise on astrocyte proliferation-related proteins in the motor cortex and hippocampus after traumatic brain injury. 定期跑步机运动对创伤性脑损伤后运动皮质和海马中星形胶质细胞增殖相关蛋白的影响。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550696.348
Woo-Hyeok Yang, Dong-Eun Kim, Tae-Beom Seo, Young-Pyo Kim
{"title":"Effect of regular treadmill exercise on astrocyte proliferation-related proteins in the motor cortex and hippocampus after traumatic brain injury.","authors":"Woo-Hyeok Yang, Dong-Eun Kim, Tae-Beom Seo, Young-Pyo Kim","doi":"10.12965/jer.2550696.348","DOIUrl":"10.12965/jer.2550696.348","url":null,"abstract":"<p><p>The purpose of this study was to investigate whether regular treadmill exercise after traumatic brain injury (TBI) positively affects the regenerative environment in the motor cortex and hippocampus of the brain. Subjects were randomly divided into three groups: the normal control (Norm, n=8), the TBI+sedentary group (TBI+SED, n=8), and the TBI+ treadmill exercise group (TBI+Ex, n=8). Following a 2-week post-TBI recovery period, treadmill exercise was performed regularly for 4 weeks. The results showed that regular walking exercise after TBI increased the expression of growth associated protein-43 and tropomyosin receptor kinase-B, which are associated with neuronal survival, in both the motor cortex and hippocampus. The TBI+SED exhibited elevated glial fibrillary acidic protein and phosphorylated mammalian target of rapamycin signaling in both the motor cortex and hippocampus of the brain. In contrast, phosphorylated phosphatase and tensin homolog (p-PTEN) expression showed region-specific patterns: in the motor cortex, p-PTEN levels were higher in the TBI+SED than the Norm group and further increased following treadmill exercise, whereas in the hippocampus, p-PTEN expression decreased after TBI but was significantly elevated in the TBI+Ex group. These findings indicated that regular exercise after TBI might reduce glial scar formation and promote neural regeneration by elevating PTEN expression and inhibiting the mammalian target of rapamycin signaling pathway.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"260-267"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-dependent effects of exercise on gut microbiota-mitochondria axis and cognitive function in aging mice. 运动对衰老小鼠肠道微生物-线粒体轴和认知功能的年龄依赖性影响。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550792.396
Sang-Seo Park, Hye-Sang Park, Ga-Ram Choi, Sang-Hoon Kim, Tae-Woon Kim
{"title":"Age-dependent effects of exercise on gut microbiota-mitochondria axis and cognitive function in aging mice.","authors":"Sang-Seo Park, Hye-Sang Park, Ga-Ram Choi, Sang-Hoon Kim, Tae-Woon Kim","doi":"10.12965/jer.2550792.396","DOIUrl":"10.12965/jer.2550792.396","url":null,"abstract":"<p><p>Aging is accompanied by progressive impairments in mitochondrial bioenergetics, apoptosis regulation, and gut microbiota homeostasis, all of which contribute to cognitive decline. In this study, we investigated whether the effects of treadmill exercise on the gut microbiota-mitochondrion-neuronal plasticity axis differed between young (15 months) and old (28 months) mice. Male C57BL/6 mice were randomly assigned to the following groups: early sedentary, early exercise, late sedentary, or late exercise groups and completed an 8-week treadmill training protocol. Cognitive function was assessed using the passive avoidance test and the Morris water maze test. Hippocampal mitochondrial respiration, Ca<sup>2+</sup> retention capacity, and Bax/Bcl-2 expression were quantified, and the gut microbiota composition was analyzed using 16S ribosomal RNA sequencing. Mice that did not exercise in old age exhibited memory impairment, decreased mitochondrial oxidative respiration, reduced Ca<sup>2+</sup> retention, increased Bax expression, decreased Bcl-2 levels, and decreased abundance of <i>Lactobacillus</i>, <i>Bifidobacterium</i>, and <i>Akkermansia</i>. Exercise significantly improved behavioral performance, mitochondrial function, and apoptosis balance, while also increasing beneficial gut microbiota. Notably, these effects were significantly greater in late-aged compared to early-aged mice. These results demonstrate that the efficacy of exercise in modulating the microbiota-mitochondrion-brain axis varies with age. Early-aged appears to represent a more responsive biological period during which exercise is more effective in improving mitochondrial integrity, microbiota composition, and cognitive resilience. These results suggest that initiating exercise early in the aging process may maximize neuroprotective effects and delay age-related functional decline.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"268-275"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145912042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinetic chain-based shoulder exercises: effects of lower extremity contribution on scapular muscle balance in individuals with and without scapular dyskinesis. 基于动力链的肩部锻炼:有或无肩胛骨运动障碍个体的下肢贡献对肩胛骨肌肉平衡的影响。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550662.331
Young-Eun Choi
{"title":"Kinetic chain-based shoulder exercises: effects of lower extremity contribution on scapular muscle balance in individuals with and without scapular dyskinesis.","authors":"Young-Eun Choi","doi":"10.12965/jer.2550662.331","DOIUrl":"10.12965/jer.2550662.331","url":null,"abstract":"<p><p>The purpose of this study was to compare the effects of kinetic chain-based forward punch plus (FPP) exercise on scapular muscle activation between individuals with scapular dyskinesis (SD) and healthy controls. A total of 30 male participants were recruited, including 15 with SD and 15 healthy individuals. Muscle activation of the upper trapezius (UT), lower trapezius (LT), serratus anterior (SA), and gluteus maximus, as well as activation ratios, were measured during FPP and FPP with contralateral leg flexion. The healthy group demonstrated decreased UT activation accompanied by increased LT and SA activation, resulting in significantly reduced UT/SA and UT/LT ratios. In contrast, the SD group showed significant increases in SA and LT; however, compensatory activation of the UT prevented improvement in muscle activation balance. These findings highlight the need for targeted neuromuscular strategies to address compensatory UT activation in individuals with SD during kinetic chain-based movements.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"307-314"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of treadmill and swimming exercises on spinal regeneration and reactive astrocytes in the brain after spinal cord injury. 跑步和游泳运动对脊髓损伤后脊髓再生和脑反应性星形胶质细胞影响的比较研究。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550686.343
Min-Jun Kim, Yeong-Jik Kim, Tae-Beom Seo
{"title":"Comparative study of treadmill and swimming exercises on spinal regeneration and reactive astrocytes in the brain after spinal cord injury.","authors":"Min-Jun Kim, Yeong-Jik Kim, Tae-Beom Seo","doi":"10.12965/jer.2550686.343","DOIUrl":"10.12965/jer.2550686.343","url":null,"abstract":"<p><p>The purpose of this study is to compare the effects of treadmill and swimming exercise on cell survival and reactive astrogliosis in the spinal cord and brain after spinal cord injury (SCI). Thirty-two male rats were randomly assigned to four groups: the normal group (Norm, n=8), the SCI+sedentary group (Seden, n=8), the SCI+treadmill exercise group (Tread, n=8), and the SCI+swimming exercise group (Swim, n=8). All rats in the SCI groups were allowed to recover for 2 weeks after injury, and then underwent 4 weeks of low-intensity treadmill and swimming exercise. In the spinal cord, both exercise interventions decreased the cavity formation around the injury, and significantly increased induction levels of growth associated protein-43, with greater improvements in the Tread group. In the motor cortex and hippocampus of the brain, the Tread group upregulated B-cell leukemia/lymphoma 2 and downregulated cleaved-caspase-3 and glial fibrillary acidic protein relative to the Seden group, indicating enhanced cell survival and reduced reactive astrogliosis in the injury site. Compared with swimming, treadmill exercise further improved tissue preservation and neural circuit-level recovery across the spinal cord, motor cortex, and hippocampus after SCI. Thus, our findings suggested evidence that treadmill exercise might be one of the rehabilitation strategies to support the spinal cord and brain after SCI.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"276-283"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of kinesiology taping leggings on exercise performance and physiological responses during CrossFit training in women aged 20-30 years. 运动机能学绑带对20-30岁女性混合健身训练中运动表现和生理反应的影响。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550742.371
Joon-Hee Kim, Sung-Heum Um, Jae-Suk Lee
{"title":"Effects of kinesiology taping leggings on exercise performance and physiological responses during CrossFit training in women aged 20-30 years.","authors":"Joon-Hee Kim, Sung-Heum Um, Jae-Suk Lee","doi":"10.12965/jer.2550742.371","DOIUrl":"10.12965/jer.2550742.371","url":null,"abstract":"<p><p>This study examined the effects of kinesiology taping leggings on exercise performance and physiological responses during CrossFit training in women aged 20-30 years. A randomized crossover design was employed with 42 healthy participants. Each participant completed two 3-week training periods wearing either taping leggings or regular leggings, separated by a 2-week washout period. Sixteen variables, including strength, endurance, power, agility, balance, proprioception, functional movement, heart-rate variability, exercise satisfaction, and lower-limb circumference, were measured. Significant improvements were observed in isokinetic strength (148.25±12.45 to 151.78±12.38 N·m), joint-position sense (2.18°±0.65° to 1.95°±0.62°), exercise satisfaction (6.85±1.42 to 7.34±1.28), and edema reduction (31.5% decrease). Most other fitness variables showed improvement trends but were not statistically significant. Taping leggings provided selective but meaningful benefits in enhancing proprioception, improving subjective satisfaction, and reducing edema during CrossFit training.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"300-306"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated effects of a 12-week intermittent combined exercise on cognitive function, physical performance, and neurophysiological biomarkers in older women. 12周间歇性联合运动对老年女性认知功能、身体表现和神经生理生物标志物的综合影响
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550788.394
Sang-Seo Park, Sang-Hoon Kim, Hye-Sun Yoon, Tae-Woon Kim
{"title":"Integrated effects of a 12-week intermittent combined exercise on cognitive function, physical performance, and neurophysiological biomarkers in older women.","authors":"Sang-Seo Park, Sang-Hoon Kim, Hye-Sun Yoon, Tae-Woon Kim","doi":"10.12965/jer.2550788.394","DOIUrl":"10.12965/jer.2550788.394","url":null,"abstract":"<p><p>Aging is associated with a progressive decline in both cognitive and physical function, and neuroinflammation and metabolic dysregulation often exacerbate this decline, particularly in older women. This study investigated the effects of a 12-week intermittent combined exercise program on cognitive function, physical performance, and neurophysiological biomarkers in community-dwelling women aged 75 years and older. Forty participants were recruited from a local welfare center and randomly assigned to an exercise group (n=20) or a control group (n=20). The exercise group participated in three supervised sessions per week that integrated aerobic exercise, resistance exercise, functional exercise, and cognitive exercise. Cognitive domains (attention, language, and memory) were assessed using the Seoul Neuropsychological Screening Test-II. Physical function was assessed using the Geriatric Physical Fitness Test (chair stand, arm flexion, grip strength, and 6-min walk). Blood samples were analyzed to measure serum brain-derived neurotrophic factor (BDNF), interleukin (IL-6), tumor necrosis factor (TNF)-α, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). Paired and independent <i>t</i>-tests were performed to evaluate pre- and posttest differences (α=0.05). After 12 weeks, the exercise group significantly improved memory (<i>P</i><0.05), lower upper-body muscle strength, grip strength, and walking endurance. Serum BDNF significantly increased (<i>P</i><0.01), and IL-6, TNF-α, LDL-C, and TG decreased (<i>P</i><0.05). HDL-C levels also significantly increased (<i>P</i><0.05). Intermittent combined exercise significantly improved cognitive and physical function and favorably modulated neurotrophic, inflammatory, and metabolic biomarkers in very elderly women.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"292-299"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eight weeks of moderate aerobic exercise on body composition and markers of inflammation and oxidative stress in middle-aged obese females. 八周适度有氧运动对中年肥胖女性身体成分及炎症和氧化应激标志物的影响。
IF 1.6
Journal of Exercise Rehabilitation Pub Date : 2025-12-22 eCollection Date: 2025-12-01 DOI: 10.12965/jer.2550690.345
Kyung-Shin Park, Paola Canales Gonzalez, Miguel Nieto, Brett S Nickerson
{"title":"Eight weeks of moderate aerobic exercise on body composition and markers of inflammation and oxidative stress in middle-aged obese females.","authors":"Kyung-Shin Park, Paola Canales Gonzalez, Miguel Nieto, Brett S Nickerson","doi":"10.12965/jer.2550690.345","DOIUrl":"10.12965/jer.2550690.345","url":null,"abstract":"<p><p>This study investigated the effects of 4-week and 8-week moderate-intensity aerobic exercise on body composition and markers of inflammation and oxidative stress in middle-aged obese Hispanic females, with a particular focus on assessing these changes independently of fat mass reduction. A total of 35 participants were randomly assigned to either an exercise group or a control group for an eight-week intervention. The exercise group performed treadmill-based aerobic training at 55% of maximal oxygen consumption, with a fixed workload adjusted for body mass and a progression from three to four weekly sessions. Body composition was assessed using dual-energy x-ray absorptiometry, and blood samples were collected at baseline, 4 weeks, and 8 weeks to analyze tumor necrosis factor-alpha (TNF-α), C-reactive protein, adiponectin, total antioxidant status (TAS), and 8-hydroxydeoxyguanosine (8-OHdG). After 8 weeks, the exercise group showed significant reductions in body fat percentage, TNF-α, and 8-OHdG, alongside an increase in TAS. Notably, by week 4, significant decreases in TNF-α and increases in TAS were observed despite no measurable changes in body weight or fat mass, indicating an early anti-inflammatory and antioxidative response to exercise independent of adiposity reduction. The findings at 4 weeks suggest that moderate aerobic exercise can independently reduce inflammation and oxidative stress, even before measurable fat loss occurs. These improvements were further enhanced by fat loss after 8 weeks, indicating that moderate aerobic exercise may reduce the risk of obesity-related disorders in middle-aged obese females, both through direct anti-inflammatory effects and by promoting fat loss.</p>","PeriodicalId":15771,"journal":{"name":"Journal of Exercise Rehabilitation","volume":"21 6","pages":"284-291"},"PeriodicalIF":1.6,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书