Journal of forensic sciences最新文献

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Police vehicle contamination by inorganic gunshot residue (iGSR) in Zagreb County Police Administration (Croatia): Analysis of characteristic and indicative particles across different vehicle parts and contributory risk factors 萨格勒布县警察局(克罗地亚)警车受无机枪弹残留物 (iGSR) 污染的情况:对不同车辆部件的特征性和指示性颗粒以及促成风险因素的分析。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-15 DOI: 10.1111/1556-4029.15628
Hrvoje Senješ MSc, Sunčica Kuzmić MSc, Ivan Jerković PhD
{"title":"Police vehicle contamination by inorganic gunshot residue (iGSR) in Zagreb County Police Administration (Croatia): Analysis of characteristic and indicative particles across different vehicle parts and contributory risk factors","authors":"Hrvoje Senješ MSc,&nbsp;Sunčica Kuzmić MSc,&nbsp;Ivan Jerković PhD","doi":"10.1111/1556-4029.15628","DOIUrl":"10.1111/1556-4029.15628","url":null,"abstract":"<p>Inorganic gunshot residue (iGSR) analysis, crucial for linking suspects to firearm use, faces challenges from potential environmental contamination, notably in police vehicles. The present study aimed to explore the level of iGSR contamination in police vehicles from the Zagreb County Police Administration (Croatia), considering particle types and their position in vehicles, and to identify associated risk factors. From December 2021 to April 2022, 65 of 86 police vehicles (margin of error: ±6% at a 95% confidence level) were sampled with GSR stubs on the drivers' seats, back seats, and backrests and analyzed using scanning electron microscopy and energy dispersive x-ray analysis (SEM/EDX). Characteristic particles were found in 63.1% of vehicles, 33.8% on the driver's seat, and 24.6% on the back seat/backrest. Indicative particles were found in 70.77% of vehicles, with a fairly even distribution. McNemar's chi-square analysis showed no significant disparities in positive sample ratios across vehicle parts or particle types (<i>p</i> &gt; 0.05). In total, 228 characteristic and 166 indicative GSR particles were identified, with no notable correlation among them (<i>p</i> = 0.346). Logistic regression analysis identified the transportation of individuals involved in firearms incidents as a statistically significant factor influencing the presence of characteristic particles (<i>p</i> = 0.030). The findings suggest a considerable prevalence of iGSR in the analyzed Police Administration unit, highlighting the need for careful contamination management in police operations to preserve evidence integrity, particularly in cases when individuals who used firearms had been transported in the vehicle.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of 105 female-perpetrated mass murders 对 105 起女性实施的大规模谋杀案的分析
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-11 DOI: 10.1111/1556-4029.15627
Ragy R. Girgis MD, Dung Hoang MA, Hannah Hesson BA, Gabriella Dishy MA, Kathryn Lee MA, Tyler Pia MA, Faizan Syed MD, Alexandra Villalobos MA, Paul S. Appelbaum MD, Gary Brucato PhD
{"title":"An analysis of 105 female-perpetrated mass murders","authors":"Ragy R. Girgis MD,&nbsp;Dung Hoang MA,&nbsp;Hannah Hesson BA,&nbsp;Gabriella Dishy MA,&nbsp;Kathryn Lee MA,&nbsp;Tyler Pia MA,&nbsp;Faizan Syed MD,&nbsp;Alexandra Villalobos MA,&nbsp;Paul S. Appelbaum MD,&nbsp;Gary Brucato PhD","doi":"10.1111/1556-4029.15627","DOIUrl":"10.1111/1556-4029.15627","url":null,"abstract":"<p>Most research on mass murderers to date has focused on perpetrators of male sex, while research on perpetrators of female sex has been relegated to case reports and series. We aimed to more fully examine the phenomenon of female-perpetrated mass murder. We analyzed 1715 worldwide incidents of personal-cause mass murder from 1900 to 2019, identifying 105 (6%) events perpetrated by females. We defined mass murder as any event involving at least three fatalities, not including the perpetrator, using any method. We identified cases of mass murder from English-language databases of mass murder or murder in print or online. There were no significant differences in age and race between female and male perpetrators. Relative to males, female perpetrators were significantly less likely to employ firearms in their mass murders, using them in less than half of cases, compared to over 70% for males. The prevalence of psychotic signs and symptoms among female mass murderers was more than double that among males (25.7% vs. 12.5%, <i>p</i> &lt; 0.01), while the rate of nonpsychotic psychiatric or neurological conditions was also much greater among female perpetrators (29.5% vs. 17.1%, <i>p</i> &lt; 0.01). Over half of female perpetrators took or attempted to take their own lives. More than three-quarters of mass murders by females involved at least one family member as a victim. This study underscores sex-specific differences in the perpetration of mass murder and the need for further research to understand how insights about such dynamics might lead to the development of more effective and informed intervention policies.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating cardiac risks of TASER: An in‐depth case study through probable current analysis 评估 TASER 的心脏风险:通过可能的电流分析进行深入案例研究
IF 1.6 4区 医学
Journal of forensic sciences Pub Date : 2024-09-11 DOI: 10.1111/1556-4029.15614
Hojeong Seo, Saehan Park, Sanghee Kim, Sookyoung Lee, Changho Choi
{"title":"Evaluating cardiac risks of TASER: An in‐depth case study through probable current analysis","authors":"Hojeong Seo, Saehan Park, Sanghee Kim, Sookyoung Lee, Changho Choi","doi":"10.1111/1556-4029.15614","DOIUrl":"https://doi.org/10.1111/1556-4029.15614","url":null,"abstract":"This study investigates the cardiac safety concerns related to TASER discharges centering on a pivotal case that marked the first TASER‐related fatality in South Korea. Employing Pratt et al.'s theoretical framework, the research evaluates the potential for ventricular fibrillation (VF) from these discharges. The methodology incorporated a high‐resolution waveform analysis using sophisticated equipment and considered specific incident details, including dart impact locations verified through a forensic examination. A human body impedance of 500 Ω, chosen based on empirical studies and coupled with non‐inductive resistance for high‐voltage handling, was utilized in the model. By applying a heart‐current factor from IEC 60479 standards, the study found a VF risk of up to 5% depending on the impact location and current pathways. In this specific case, although the calculated risk did not exceed critical thresholds, the VF risk was high enough to suggest that TASER discharges played a role in the fatal outcome. This study underscores the importance of dart impact location in TASER safety evaluations, contributing to a broader understanding of TASER cardiac risks and providing a basis to advocate for rigorous safety protocols.","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poisoning with table salt while treating drug poisoning 治疗药物中毒时食盐中毒
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-10 DOI: 10.1111/1556-4029.15623
Anna Smędra MD, PhD, Katarzyna Wochna DMD, PhD, Jacek Gruchała MD, PhD, Jarosław Berent MD, PhD
{"title":"Poisoning with table salt while treating drug poisoning","authors":"Anna Smędra MD, PhD,&nbsp;Katarzyna Wochna DMD, PhD,&nbsp;Jacek Gruchała MD, PhD,&nbsp;Jarosław Berent MD, PhD","doi":"10.1111/1556-4029.15623","DOIUrl":"10.1111/1556-4029.15623","url":null,"abstract":"<p>Hypernatremia is an increase in serum sodium concentration above 145 mmol/L. There are many causes of elevated sodium levels in the blood serum. One is incorrect actions performed by medical staff. The symptoms of excessively high serum sodium levels depend on the severity of hypernatremia, the rate of its increase and the accompanying volume disorders. Severe symptoms include altered consciousness, increased muscle tone and reflexes, convulsions, psychomotor hyperactivity or drowsiness (up to coma), respiratory failure, and even death. We present the case of a 45-year-old man who took seven tablets of a blood pressure-lowering drug, and paramedics subsequently administered a concentrated solution of table salt to induce vomiting. However, vomiting did not occur, leading to hypernatremia. Ultimately, the man survived but developed persistent cognitive dysfunction, including disordered short-term memory and encoding and retrieval of information from long-term memory, weakening of attention function and fatigue, and disorders in abstract thinking. The patient's family went to the prosecutor's office to investigate the possibility of medical malpractice. Experts found that the paramedics' actions were incorrect. Although it has been known for many years that table salt solutions should not be used to induce vomiting, unfortunately, both laypeople and medical professionals are still using this technique. Iatrogenic salt poisoning may end not only in serious health complications but also in legal consequences.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns in paternal and maternal filicide: A comparative analysis of filicide cases in Turkey 杀父和杀母的模式:土耳其杀父和杀母案件的比较分析
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-10 DOI: 10.1111/1556-4029.15625
Tuba Özcanlı MD, İhsan Okur MD, Cana Aksoy Poyraz MD, Neşe Kocabaşoğlu MD, Hızır Aslıyüksek MD
{"title":"Patterns in paternal and maternal filicide: A comparative analysis of filicide cases in Turkey","authors":"Tuba Özcanlı MD,&nbsp;İhsan Okur MD,&nbsp;Cana Aksoy Poyraz MD,&nbsp;Neşe Kocabaşoğlu MD,&nbsp;Hızır Aslıyüksek MD","doi":"10.1111/1556-4029.15625","DOIUrl":"10.1111/1556-4029.15625","url":null,"abstract":"<p>Filicide is the act of a parent killing their own offspring. Previous studies indicate that there are both commonalities and distinctions between filicides committed by mothers and fathers. The main objective of this study was to compare maternal and paternal filicide with a major focus on clinical and sociodemographic features of perpetrators, incident details, and victims. Filicide cases were examined at the bedded unit of the Expertise Department of Observation of the Council of Forensic Medicine that were referred by the Turkish Ministry of Justice. A total of 51 perpetrators and 57 victims were analyzed from June 2014 to December 2023. The perpetrators were daily face-to-face interviewed by psychiatry and forensic medicine physicians. There were significant differences in sociodemographic characteristics and psychiatric conditions between maternal and paternal cases. Female perpetrators tended to be younger, unemployed, mostly targeted younger victims and used asphyxiation to kill, whereas males tended to target older victims and utilized firearms. The most common primary cause of filicide in maternal cases was “unwanted pregnancy,” whereas “spousal revenge” and “anger or impulsivity” were predominant in paternal filicides. All perpetrators who were not criminally responsible were mothers, mostly diagnosed with psychotic depression. Unwanted pregnancy, psychotic depression, and postpartum psychosis should be assessed when evaluating risk for mothers, especially for infanticide. The desire for revenge on a spouse, often seen with personality disorders, impulsivity and anger, access to firearms should be screened for risk of paternal filicide, particularly in older victims. Early recognition of these factors can help in implementing prevention strategies.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15625","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142217128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual detection and enhancement of alterations in questioned documents by Mueller polarimetry 利用穆勒偏振测量法对受质疑文件中的篡改进行视觉检测和增强。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15617
Emanuel Chironi PhD, Claudio Iemmi PhD
{"title":"Visual detection and enhancement of alterations in questioned documents by Mueller polarimetry","authors":"Emanuel Chironi PhD,&nbsp;Claudio Iemmi PhD","doi":"10.1111/1556-4029.15617","DOIUrl":"10.1111/1556-4029.15617","url":null,"abstract":"<p>In this article, we have explored the use of Mueller polarimetry for the detection and enhancement of alterations in questioned documents. Erasures, obliterations (with liquid paper and by pasting an additional layer of paper), and insertions (made with several inks) were studied in both regular and glossy paper. Promising results were obtained, which depend on the type of paper and the relation between the color of the ink and that of the illuminating light source. Erasures are easier to detect in glossy paper than in regular paper. Obliterations with liquid paper produced successful results in both types of paper, while detection of obliterations made with an additional layer of paper led to higher contrast for regular paper. Regarding the insertions, the black ball-point ink could be differentiated from roller-ball and gel-pen ink, which is often difficult to achieve visually. The contrast observed between the two inks was higher for regular paper than for glossy paper. Although the results shown in this article are promising, a wider variety of papers and pen types must be tested to further develop the procedure. It has the advantage of being non-destructive and far more economic than other methods. In some cases, the results can be complementary to those obtained by other methods (e.g., fluorescence with UV excitation and illumination with transmitted and oblique light), while in other cases the method offers unique advantages.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two simplified tooth sample preparation methods for conventional laboratory and RapidHIT™ ID workflows 两种简化的牙齿样本制备方法,适用于传统实验室和 RapidHIT™ ID 工作流程。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15624
Morgan Eaton BS, M. Shane Woolf PhD, Samyuktha Pemmasani, Triniti Turner BS, Janina Golob Deeb DMD, MS, Tracey Dawson Green PhD
{"title":"Two simplified tooth sample preparation methods for conventional laboratory and RapidHIT™ ID workflows","authors":"Morgan Eaton BS,&nbsp;M. Shane Woolf PhD,&nbsp;Samyuktha Pemmasani,&nbsp;Triniti Turner BS,&nbsp;Janina Golob Deeb DMD, MS,&nbsp;Tracey Dawson Green PhD","doi":"10.1111/1556-4029.15624","DOIUrl":"10.1111/1556-4029.15624","url":null,"abstract":"<p>Disaster victim identification (DVI) refers to the forensic identification of unknown individuals following a mass disaster event. Human dental structures can contain viable DNA sources when other soft tissues are compromised. However, labor-intensive sample preparation performed by extensively trained personnel is needed to expose the nuclear material for traditional forensic DNA workflows. With this in mind, we evaluated two simplified sample preparation protocols for processing tooth samples using either a conventional forensic DNA workflow or the Applied Biosystems® RapidHIT™ ID instrument. Briefly, sample sets for both protocols included 10 deciduous teeth that were cleaned prior to either fragmentation with a claw hammer (for RapidHIT™ ID processing) or fine-powder pulverization with a consumer-grade coffee grinder (for traditional workflows). The average percentage of expected STR alleles that were detected above analytical threshold for these tooth samples were comparable between methods: RapidHIT™ ID = 99.0% and GlobalFiler™ = 99.8%. Average intralocus heterozygote peak height ratios (PHRs) were comparable: RapidHIT™ ID = 0.80 and GlobalFiler™ = 0.86. Importantly, 9 of 10 samples analyzed via the RapidHIT™ ID required analyst review for flagged artifact peaks and quality issues. Across all profiles, 91% of alleles passed quality metrics for the RapidHIT™ workflow versus 100% for conventional GlobalFiler™ analysis. Collectively, these results suggest that quick, low-tech tooth sample fragmentation followed by analysis with the RapidHIT™ ID instrument can produce complete STR profiles from aged tooth samples. Future studies should include larger samples sets, more challenging tooth samples, and further simplification of sample preparation to enable field-forward, on-scene DVI.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15624","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: A study of DNA transfers onto plastic packets placed in personal bags 对 "关于将 DNA 转移到放在个人包中的塑料袋上的研究 "的更正。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15618
{"title":"Correction to: A study of DNA transfers onto plastic packets placed in personal bags","authors":"","doi":"10.1111/1556-4029.15618","DOIUrl":"10.1111/1556-4029.15618","url":null,"abstract":"<p>Lee LYC, Lee YS, Tan J, Lee JY, Syn CK. A study of DNA transfers onto plastic packets placed in personal bags. J Forensic Sci. 2024;69(2):430–6. https://doi.org/10.1111/1556-4029.15460</p><p>In section 2.2 DNA Processing, there is a missing character ‘1’ immediately after ‘3 to’ in the text.</p><p>The current text reads: “In general, the proportion of major to minor contributors should be at least 3 to and any profile with three or more contributors at an indistinct level would be deemed not interpretable.”</p><p>The correct text should read: “In general, the proportion of major to minor contributors should be at least 3 to 1 and any profile with three or more contributors at an indistinct level would be deemed not interpretable.”</p><p>We apologize for this error.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15618","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of GPR signals over simulated clandestine graves with domestic pigs (Sus Scrofa domesticus) and human remains 家猪(Sus Scrofa domesticus)和人类遗骸在模拟地下坟墓上的 GPR 信号比较。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15622
Aidan Armstrong, Kennedy O. Doro PhD, Katrina Cristino, Agathe Ribéreau-Gayon PhD, Shari L. Forbes PhD, William T. D. Wadsworth MA, Carl-Georg Bank PhD
{"title":"Comparison of GPR signals over simulated clandestine graves with domestic pigs (Sus Scrofa domesticus) and human remains","authors":"Aidan Armstrong,&nbsp;Kennedy O. Doro PhD,&nbsp;Katrina Cristino,&nbsp;Agathe Ribéreau-Gayon PhD,&nbsp;Shari L. Forbes PhD,&nbsp;William T. D. Wadsworth MA,&nbsp;Carl-Georg Bank PhD","doi":"10.1111/1556-4029.15622","DOIUrl":"10.1111/1556-4029.15622","url":null,"abstract":"<p>Studies assessing the use of ground-penetrating radar (GPR) for locating unmarked human graves commonly use pigs as proxies, with recent concerns about the adequacy of pigs as substitutes for humans. Also, there is little agreement on how to identify and describe GPR signals associated with graves. Hence, this project's aim is to compare GPR signals acquired over simulated clandestine graves with pig and human remains. We established human, pig, and control graves at the REST[ES] human decomposition facility in May 2022 and monitored the graves over 17 months using a 250 MHz antenna GPR system. Our results showed the presence of perturbed and V-shaped reflectors, diffraction hyperbolas, and reflectors with amplitude loss at depth between 0.6 and 0.75 m in the radargram for graves with human and pig remains. We corroborate recent studies which concluded that the use of proxies is a viable alternative to human cadavers. The observed radar signatures were classified into five key patterns, which are characteristic of similar data collected with 250 MHz above graves reported in the literature. These classes are: V-shaped dipping reflections from grave walls (class A), small hyperbolic reflections superimposed onto a near-linear reflector (class B), hyperbolic reflections from remains within the grave (class C), new high-amplitude reflection patterns (class D) and significant loss or interruption of reflections (class E). Our proposed classification can help streamline future investigations where the goal is to interpret burials within large GPR datasets and provide language to communicate these results to the broader scientific community.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1556-4029.15622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute aconitine poisoning resulting from the ingestion of medicinal liquor 摄入药酒导致急性乌头碱中毒。
IF 1.5 4区 医学
Journal of forensic sciences Pub Date : 2024-09-04 DOI: 10.1111/1556-4029.15621
Ruoyu Huang MD, Qiuyu Pang MD, Lexin Zheng MD, Rui Duan BSc, Ying Wang PhD, Zhiyong Wang BSc, Tao Wang MD, PhD
{"title":"Acute aconitine poisoning resulting from the ingestion of medicinal liquor","authors":"Ruoyu Huang MD,&nbsp;Qiuyu Pang MD,&nbsp;Lexin Zheng MD,&nbsp;Rui Duan BSc,&nbsp;Ying Wang PhD,&nbsp;Zhiyong Wang BSc,&nbsp;Tao Wang MD, PhD","doi":"10.1111/1556-4029.15621","DOIUrl":"10.1111/1556-4029.15621","url":null,"abstract":"<p>Diester diterpenoid alkaloids (DDAs) are the main active ingredients of herbaceous perennial plants <i>Aconitum</i>. DDAs possess cardiotoxic and neurotoxic properties. Although most deaths caused by DDA poisoning are accidental, a few instances of suicide and homicide have been reported. Presented is a case of an acute aconitine (AC) poisoning following the ingestion of approximately 50 mL of homemade medicinal liquor. We described the clinical manifestations after poisoning and detailed postmortem changes, and detected the concentrations of AC and hypaconitine (HA) by liquid chromatography–tandem mass spectrometry (LC–MS/MS). The decedent experienced a burning sensation in the gastrointestinal tract after poisoning, followed by flushing and paralysis of the face and limbs, and severe cardiac arrhythmia. An autopsy revealed cyanosis of the lips and nail beds; conjunctival hemorrhage in both eyes; pulmonary edema; tissue hemorrhage and congestion in multiple organs; and inflammatory cell infiltration in the stomach, duodenum, pancreas, and cardiac muscle. The concentrations of AC and HA were as follows: cardiac blood, 38.4 ng/mL and 7.1 ng/mL; pericardial fluid, 7.3 ng/mL and 41 ng/mL; urine, 28.1 ng/mL and 574 ng/mL; bile, 38.5 ng/mL and 108 ng/mL; gastric contents, 0.06 mg and 0.56 mg; liver tissue, 10.7 ng/g and 109.6 ng/g; and medicinal liquor, 0.568 mg/mL and 0.664 mg/mL, respectively. The clinical manifestations, anatomy findings, and quantitative data on the concentrations of AC and HA in body fluids and tissues will aid forensic investigations of deaths caused by acute AC poisoning.</p>","PeriodicalId":15743,"journal":{"name":"Journal of forensic sciences","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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