Journal of endourologyPub Date : 2025-03-01Epub Date: 2025-02-10DOI: 10.1089/end.2024.0714
María Elena Martínez-Corral, Olalla Vázquez-Cancela, Cristina Fernández-Pérez, Daniel A Pérez-Fentes
{"title":"Impact of Obesity on the Outcomes of Supine Percutaneous Nephrolithotomy: A Propensity Score Analysis.","authors":"María Elena Martínez-Corral, Olalla Vázquez-Cancela, Cristina Fernández-Pérez, Daniel A Pérez-Fentes","doi":"10.1089/end.2024.0714","DOIUrl":"10.1089/end.2024.0714","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> The aim of this study was to evaluate whether obesity could influence the success and safety of percutaneous nephrolithotomy (PCNL) performed in the supine position. <b><i>Patients and Methods:</i></b> This prospective cohort study included 664 patients who underwent supine PCNL between September 2008 and June 2023. Patients were stratified into two groups: obese (272 patients) and nonobese (392 patients). To minimize bias, a 1:1 matching was performed between the groups based on Guy's stone score, preoperative stone burden, and potential confounding variables. Procedural success was defined as the complete absence of stones on CT performed 3 months postoperatively. Safety was assessed by the incidence of overall, infectious, and hemorrhagic complications, with complications graded using the modified Clavien-Dindo classification. <b><i>Results:</i></b> The obese patient group showed a significantly higher prevalence of hypertension, diabetes mellitus, and higher anesthetic risk according to the American Society of Anesthesiologists' classification. However, the complexity of the cases and the surgical technique employed were compared between the two groups. In the univariate analysis, no significant differences were observed in success rates (<i>p</i> = 0.118), overall complications (<i>p</i> = 0.222), hemorrhagic (<i>p</i> = 0.104), or infectious complications (<i>p</i> = 0.326). After matching, a significant reduction in hemorrhagic complications was identified in the obese patient group (odds ratio 0.43; 95% confidence interval: 0.18-0.97; <i>p</i> = 0.027). However, obesity was not associated with an increased likelihood of overall (<i>p</i> = 0.093) or infectious complications (<i>p</i> = 0.869), nor did it affect procedural success (<i>p</i> = 0.219). <b><i>Conclusions:</i></b> Obesity should not compromise the success or safety of PCNL when performed in the supine position. On the contrary, it may offer a protective effect against hemorrhagic complications. These findings suggest that supine PCNL is a safe and effective surgical option for obese patients, and obesity should not be regarded as a contraindication when the procedure is otherwise indicated.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"237-244"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2025-01-27DOI: 10.1089/end.2024.0923
Shubham Kumar, Ahmad Neyazi, Rachana Mehta, Ranjana Sah
{"title":"Comment on \"The Safety and Feasibility of Ambulatory Minimally Invasive Partial Nephrectomy: A Systematic Review and Meta-Analysis\".","authors":"Shubham Kumar, Ahmad Neyazi, Rachana Mehta, Ranjana Sah","doi":"10.1089/end.2024.0923","DOIUrl":"10.1089/end.2024.0923","url":null,"abstract":"","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"e324-e325"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meghan F Davis, Arun K Srinivasan, Sameer Mittal, Aseem R Shukla
{"title":"Pediatric Robotic Assisted Laparoscopic Pyeloplasty.","authors":"Meghan F Davis, Arun K Srinivasan, Sameer Mittal, Aseem R Shukla","doi":"10.1089/end.2024.0399","DOIUrl":"https://doi.org/10.1089/end.2024.0399","url":null,"abstract":"<p><p>Ureteropelvic junction obstruction (UPJO) is a common cause of hydronephrosis in the pediatric population. Management with an open dismembered pyeloplasty was first described by Anderson-Hynes in 1949; minimally invasive approaches have been increasingly utilized. In the subsequent text and accompanying video, we review the technique for dismembered robotic assisted laparoscopic pyeloplasty in the pediatric population. Large retrospective series demonstrate an over 90% success rate for robotic assisted laparoscopic pyeloplasty. Given success and complication rates are similar to an open approach, utilization of this approach will likely continue to increase.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":"39 S1","pages":"S60-S65"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotic Multiport Buccal Mucosa Graft Ureteroplasty: Tips and Tricks.","authors":"Brian W Chao, Matthew Lee, Daniel D Eun","doi":"10.1089/end.2024.0342","DOIUrl":"https://doi.org/10.1089/end.2024.0342","url":null,"abstract":"<p><p>Robotic buccal mucosa graft ureteroplasty (RU-BMG) has become a cornerstone in the armamentarium of robotic ureteral reconstruction. Previously, long-segment strictures of the proximal and mid-ureter were relegated to aggressive reconstructive options such as ileal ureter substitution and renal autotransplantation. RU-BMG has emerged as an option for repair with comparatively minimal morbidity and excellent success rates. We herein present a detailed description of our pre- and postoperative considerations, operative techniques, and tips and tricks. The accompanying video provides multiple examples of intraoperative decision-making and technical nuances to maximize efficiency and efficacy.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":"39 S1","pages":"S52-S59"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Netsch, Andreas J Gross, Benedikt Becker
{"title":"Thulium Laser Enucleation of the Prostate.","authors":"Christopher Netsch, Andreas J Gross, Benedikt Becker","doi":"10.1089/end.2024.0617","DOIUrl":"https://doi.org/10.1089/end.2024.0617","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Anatomical endoscopic enucleation of the prostate (AEEP) is considered a size-independent method for treating lower urinary tract symptoms (LUTS) secondary to benign prostatic obstruction (BPO) according to current international BPO guidelines. AEEP offers less perioperative morbidity compared with traditional transurethral resection of the prostate (TURP) or open prostatectomy while providing comparable long-term durability to open prostatectomy. The thulium fiber laser (TFL) is one prominent energy source for AEEP, which has been widely adopted around the world. We present a step-by-step surgical approach to thulium laser enucleation of the prostate (ThuLEP) using the TFL, describing a modified en-bloc technique for AEEP. <b><i>Materials and Methods:</i></b> In this video, a modified en-bloc technique is presented, performed by one surgeon (C.N.) at our institution. <b><i>Results:</i></b> In this example, the outcomes of the en-bloc technique are similar to those of traditional two- or three-lobe techniques. <b><i>Conclusions:</i></b> ThuLEP as a treatment for LUTS secondary to BPO results in excellent patient outcomes and can be offered as a treatment of choice for prostates of any size.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":"39 S1","pages":"S2-S7"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2025-02-05DOI: 10.1089/end.2024.0347
Adriana M Pedraza, Ethan L Ferguson, Roxana Ramos-Carpinteyro, Nicolas Soputro, Jaya S Chavali, Carter Mikesell, Jane K Nguyen, Jihad Kaouk
{"title":"Single-Port Robotic Transvesical Partial Prostatectomy: A Novel Approach for Focal Treatment in Prostate Cancer.","authors":"Adriana M Pedraza, Ethan L Ferguson, Roxana Ramos-Carpinteyro, Nicolas Soputro, Jaya S Chavali, Carter Mikesell, Jane K Nguyen, Jihad Kaouk","doi":"10.1089/end.2024.0347","DOIUrl":"10.1089/end.2024.0347","url":null,"abstract":"<p><p><b><i>Introduction and Objective:</i></b> Given the favorable cancer-specific survival rates in localized prostate cancer and the negative impact of whole-gland treatments on functional outcomes, the field is moving toward precision strategies such as focal therapy and organ-sparing surgery. We aim to report medium-term functional and oncologic outcomes for the initial Single-Port Robotic Transvesical Partial Prostatectomy (SP-TVRAPP) patient cohort. <b><i>Materials and Methods:</i></b> We analyzed a prospectively maintained database of 20 patients who underwent SP-TVRAPP between February 2021 and March 2024. Inclusion criteria were prostate-specific antigen (PSA) ≤10 ng/mL, clinical stage ≤ cT2b, ISUP Grade Group ≤3, unilateral lesions on multiparametric magnetic resonance imaging (mpMRI) with positive biopsy cores on the same side, and preoperative IIEF-5 ≥ 17. We also considered bilateral prostate cancer in the anterior zone and invisible mpMRI tumors confirmed by unilateral positive biopsies. <b><i>Results:</i></b> At baseline, patients had an average age of 61 years, a median PSA of 4.8 ng/mL (interquartile range [IQR]: 3.7-7.7), and a median Sexual Health Inventory for Men (SHIM) score of 24 (IQR: 18-25). All procedures were completed without complications, need for additional ports, or conversion. After a median hospital stay of 4.2 hours, 94% of cases were discharged without opioid prescriptions, and Foley catheters were removed after approximately 4 days. At 6 weeks, 3, 6, and 12 months postprocedure, potency rates, defined as a SHIM score ≥17, were 45.0%, 77.7%, 83.3%, and 87.5%, respectively. When potency was defined as having erections sufficient for penetration, the rates were 80.0%, 88.8%, 88.8%, and 93.7% for the same time intervals. Regarding urinary function, 60.0% were continent at 1 week, increasing to 85.0% by 6 weeks, 88.8% at both 3 and 6 months, and reaching 93.7% at 12 months postsurgery. Oncologically, 30.0% experienced upgrading and 40.0% upstaging within this cohort. Negative surgical margins were attained in 85.0% of the cases and the median PSA was 0.4 ng/mL 12 months after SP-TVRAPP. Two men were found to have residual GG1 cancer in the protocol biopsies and are currently on active surveillance. At a mean follow-up of 15.5 months (0.2-34.8) months, none of the patients has required secondary interventions, and all remain free of both clinically significant residual prostate cancer and metastatic disease. <b><i>Conclusions:</i></b> SP-TVRAPP represents a promising treatment for certain patients with localized prostate cancer. This targeted surgical method has been associated with faster postoperative recovery and has demonstrated high rates of early recovery in erectile function and urinary continence while ensuring oncologic safety.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"261-270"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2024-11-26DOI: 10.1089/end.2024.0428.fts24
Pier Paolo Avolio, Toufic Hassan, Abdulmalik Addar, Hend Alshamsi, Victor McPherson, Nicolò Maria Buffi, Giovanni Lughezzani, Oleg Loutochin, Alexis Rompré-Brodeur, Maurice Anidjar, Rafael Sanchez-Salas
{"title":"The Role of Tumor Volume Ratio in Predicting Clinically Significant Prostate Cancer on Transperineal Biopsy.","authors":"Pier Paolo Avolio, Toufic Hassan, Abdulmalik Addar, Hend Alshamsi, Victor McPherson, Nicolò Maria Buffi, Giovanni Lughezzani, Oleg Loutochin, Alexis Rompré-Brodeur, Maurice Anidjar, Rafael Sanchez-Salas","doi":"10.1089/end.2024.0428.fts24","DOIUrl":"10.1089/end.2024.0428.fts24","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> Multiparametric magnetic resonance imaging (mpMRI) has made dramatic inroads into the management of localized prostate cancer (PCa); however, not all suspicious lesions represent clinically significant (cs) PCa. We aimed to analyze the hypothetical effect of incorporating tumor volume ratio (TVR) into prostate biopsy (PBx) decision-making. <b><i>Materials and Methods:</i></b> Two hundred and fifty-two patients with suspicious lesions at mpMRI undergoing transperineal PBx under local anesthesia between 2019 and 2022 were retrospectively evaluated. TVR was calculated by dividing the tumor volume by the prostate volume. A regression model was used to assess predictors of csPCa. Descriptive statistics were applied to evaluate the effect of including TVR in PBx decision-making. <b><i>Results:</i></b> Overall, 119 patients (47%) were found to have csPCa. Age (<i>p</i> < 0.001), prior negative PBx (<i>p</i> = 0.011), and TVR (<i>p</i> < 0.001) were found to be independent predictors of csPCa. Applying the TVR cutoff of 0.23, a total of 117/252 (46%) PBx would have been avoided at the cost of missing csPCa in 26 (10%) men. <b><i>Conclusions:</i></b> Age, previous biopsy status, and TVR were found to be independent predictors of csPCa in men with suspicious lesions at mpMRI. Implementation of TVR into PBx decision-making improves the accuracy of mpMRI. Future studies are required to validate our findings and evaluate the role of TVR in avoiding unnecessary PBx.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"S47-S53"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2025-02-06DOI: 10.1089/end.2024.0720
Lara Rodriguez-Sanchez, Sonya A Lehmann, Michael W Kattan, Alberto Lopez-Prieto, Luis Avila-Moreno, Gloria Egui-Benatuil, Fernando J Bianco
{"title":"MRI Fusion Cryoablation: Is There an Outcome Difference Between Anterior and Posterior Lesions?","authors":"Lara Rodriguez-Sanchez, Sonya A Lehmann, Michael W Kattan, Alberto Lopez-Prieto, Luis Avila-Moreno, Gloria Egui-Benatuil, Fernando J Bianco","doi":"10.1089/end.2024.0720","DOIUrl":"10.1089/end.2024.0720","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Cryotherapy pioneered ablation therapy for prostate cancer (PCa), initially using larger ablations. As the technique advanced, a more targeted approach was developed irrespective of lesion location. However, some clinical guidelines have addressed concerns for treating posterior areas. This study evaluates the validity of these concerns. <b><i>Materials and Methods:</i></b> We retrospectively studied 814 Magnetic Resonance Imaging Fusion Target Cryotherapy (MRFTC) treatment-naïve patients with PCa with a single index lesion (2013-2023) under local anesthesia. We grouped by treatment location: anterior, anterior-posterior, and posterior. Disease progression, defined as conversion to radical treatment, initiation of hormonal therapy, or development of metastases, was evaluated with survival analysis via the Kaplan-Meier log-rank test. Univariate and multivariable analyses were employed to compare outcomes among different treatment groups and other risk factors. Functional outcomes were evaluated using the Sexual Health Inventory for Men (SHIM) and International Prostate Symptom Score questionnaires, with comparisons made over time and by lesion location through <i>t</i>-tests. Complication rates were documented across the various treatment areas. <b><i>Results:</i></b> The distribution of patients' characteristics across treatment groups was similar. Procedure pain scores were similar irrespective of lesion location. Five years post-MRFTC, 87%, 89%, and 90% of patients treated for anterior, anterior-posterior, and posterior lesions, respectively, remained progression-free with no significant variation between groups (<i>p</i> = 0.22). For all groups, there were significant improvements in urinary function (baseline vs. 3 months). The posterior group showed a marginal, yet statistically significant negative difference in SHIM scores at 3 months. However, the score recovered by 1 year where no additional significant changes were noted. The most common complication was urinary retention and no cases of rectal fistula were reported. <b><i>Conclusions:</i></b> Our findings challenge clinical guidelines suggesting avoidance of focal cryoablation for posterior lesions. Using MRFTC, cryotherapy has proven to be safe and effective, regardless of lesion location.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"S21-S28"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2024-11-29DOI: 10.1089/end.2024.0619
Charles Hesswani, Pier-Paolo Avolio, Alexis Rompre-Brodeur, Sangeet Ghai, Maurice Anidjar, Adam Kinnaird, Joseph Chin, Nathan Perlis, Mostapha Soytas, Miles Mannas, Ardalanejaz Ahmad, Lawrence Klotz, Simon Tanguay, Wassim Kassouf, Victor McPherson, Armen Aprikian, Peter Pinto, Rafael Sanchez-Salas
{"title":"Navigating Focal Therapy for Prostate Cancer: Contemporary Perspectives and Future Trajectories in the Canadian Context.","authors":"Charles Hesswani, Pier-Paolo Avolio, Alexis Rompre-Brodeur, Sangeet Ghai, Maurice Anidjar, Adam Kinnaird, Joseph Chin, Nathan Perlis, Mostapha Soytas, Miles Mannas, Ardalanejaz Ahmad, Lawrence Klotz, Simon Tanguay, Wassim Kassouf, Victor McPherson, Armen Aprikian, Peter Pinto, Rafael Sanchez-Salas","doi":"10.1089/end.2024.0619","DOIUrl":"10.1089/end.2024.0619","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This article equips Canadian urologists with the latest advancements in focal therapy (FT) principles and outcomes while providing an overview of its current landscape in Canada, including challenges and future directions. <b><i>Methods:</i></b> We conducted a nonsystematic review of the literature on FT in urology and prostate cancer (PCa), focusing on Canadian-led studies. Articles were identified using PubMed, MEDLINE, and Google Scholar and selected based on relevance and originality. The final search was completed in April 2024. A survey was also conducted among Canadian urologists and radiologists practicing FT. It covered their experiences, access to technology, implementation challenges, and reimbursement policies. Data were collected via video calls, phone calls, or email, and responses were reported anonymously. <b><i>Results:</i></b> Fourteen Canadian urologists and radiologists performing FT were contacted, and 12 participated in this study. Despite the increasing adoption of FT by Canadian urologists, nationwide implementation remains limited due to financial constraints and resource shortages. This has restricted the availability of FT for Canadian men with PCa compared with their American and European counterparts. Only two provinces-Saskatchewan and Alberta-currently have billing codes for FT, forcing patients elsewhere to either join clinical trials or pay out of pocket. To close this care gap, equitable health care coverage and integration of FT into standard treatment options are essential. <b><i>Conclusion:</i></b> The quality of research in FT is showing promising improvements, with several clinical trials currently underway that may pave the way for broader acceptance within clinical guidelines by multiple urological societies. Although Canada has been slower to adopt FT compared with other parts of the world, Canadian urologists continue to advocate for provincial health care coverage to ensure that this innovative technology becomes accessible to Canadian patients.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":"S29-S37"},"PeriodicalIF":2.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endourologyPub Date : 2025-03-01Epub Date: 2025-02-11DOI: 10.1089/end.2024.0581
Ivan Schwartzmann, Pedro Hernandez-Peñalver, Alba Farré Alejo, Paula Izquierdo Gonzalez, Laura Mas Grillo, Maria Montlleó, Enver Moncada Castro, Pietro Diana, Alberto Breda, Joan Palou, Javier Ponce de Leon Roca