{"title":"<i>Response to Letter:</i> Reply Letter to Dr. Kumar et al. on: Enhanced Artificial Intelligence in Bladder Cancer Management: A Comparative Analysis and Optimization Study of Multiple Large Language Models.","authors":"Kun-Peng Li, Chen-Yang Wang, Li Yang","doi":"10.1089/end.2025.0426","DOIUrl":"https://doi.org/10.1089/end.2025.0426","url":null,"abstract":"","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Chen, Ying Wang, Shengmei Zhu, Jiani Yuan, Wen Zong
{"title":"An At-Home Monitoring Device and Remote Nursing Protocol to Prevent Nephrostomy Tube Dislodgement in Children: A Single-Center Retrospective Study.","authors":"Yi Chen, Ying Wang, Shengmei Zhu, Jiani Yuan, Wen Zong","doi":"10.1089/end.2023.0458","DOIUrl":"10.1089/end.2023.0458","url":null,"abstract":"<p><p><b><i>Purpose:</i></b> The study was to assess the effects of an at-home monitoring device and remote nursing protocol (early warning system) for children undergoing nephrostomy. <b><i>Methods:</i></b> This observational, descriptive, and retrospective study recruited 58 children who underwent nephrostomy between January 2018 and December 2019 at Xinhua Hospital, Shanghai Jiao Tong University School of Medicine. The patients were divided into an early warning system group (<i>n</i> = 32) and a conventional nurse group (<i>n</i> = 26), according to the catheter monitoring method. The primary endpoint was catheter-associated complications, whereas the secondary endpoints included parental satisfaction and the Pediatric Renal Caregiver Burden Scale (PR-CBS). <b><i>Results:</i></b> Patients in the early warning system group were associated with a reduced risk of catheter-associated complications compared to those in the conventional system group [OR, 0.019; 95% confidence interval (CI): 0.004-0.092; <i>P</i> < 0.001]. For specific catheter-associated complications, the risk of catheter detachment (OR, 0.060; 95% CI: 0.004-0.991; <i>P</i> = 0.048), poor drainage (OR: 0.061; 95% CI: 0.007-0.523; <i>P</i> = 0.011), and retrograde infection (OR: 0.195; 95% CI: 0.046-0.822; <i>P</i> = 0.026) in the early warning system group was lower than that in the conventional nurse group. Furthermore, overall parental satisfaction was higher in the early warning system group than in the conventional nurse group (<i>P</i> = 0.016). The PR-CBS score for each domain in the early warning system group was lower than that in the conventional nurse group (<i>P</i> < 0.001). <b><i>Conclusions:</i></b> Using an early warning system could improve catheter-associated complications, parental satisfaction, and PR-CBS in children undergoing nephrostomy during continuous nursing.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Letter:</i> \"The Safety and Feasibility of Ambulatory Minimally Invasive Partial Nephrectomy: A Systematic Review and Meta-Analysis\" by Paynter et al.","authors":"Miao He, Kun-Peng Li","doi":"10.1089/end.2025.0363","DOIUrl":"https://doi.org/10.1089/end.2025.0363","url":null,"abstract":"","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeni Elizabeth Mathew, Atanu Kumar Pal, Thekke Adiyat Kishore
{"title":"\"Partial Nephrectomy with Veriset: A Renorrhaphy-Less Approach\".","authors":"Jeni Elizabeth Mathew, Atanu Kumar Pal, Thekke Adiyat Kishore","doi":"10.1089/end.2024.0844","DOIUrl":"https://doi.org/10.1089/end.2024.0844","url":null,"abstract":"<p><p><b><i>Introduction and Objectives:</i></b> Renorrhaphy during partial nephrectomy is technically challenging and can extend the warm ischemia time (WIT). This study investigates the use of Veriset™ as an alternative to renorrhaphy in robot-assisted partial nephrectomy (RAPN) and presents our findings. <b><i>Methods:</i></b> In this retrospective analysis, 43 patients who had Veriset patch placed on the tumor bed post resection were compared against 43 patients who underwent conventional single-layer renorrhaphy for RAPN from January 2023 to January 2024 at our institution. The two groups underwent propensity score matching based on age, body mass index, and R.E.N.A.L. nephrometry score. Data of all patients, including patient demographic details, tumor characteristics including size, location, pre- and postoperative blood investigations, intraoperative findings, blood loss, postoperative course, complications, and follow-up of 6 months duration, were recorded. <b><i>Results:</i></b> The mean age of the study population was 52.62 ± 13.31 years, and the mean nephrometry score was 6.64 ± 1.91. The Veriset patch application failed in three patients (6.97%) and cortical renorrhaphy had to be performed for hemostasis. The Veriset group (VG) had significantly less console time and WIT when compared with renorrhaphy group (RG) (82.02 ± 25.17 minutes and 11.95 ± 10.02 minutes, respectively, <i>vs</i> 95.53 ± 29.80 minutes and 17.63 ± 6.59 minutes; <i>p</i> = 0.014 and <i>p</i> < 0.001, respectively). The RG witnessed a significant reduction in estimated glomerular filtration rate (eGFR) on postoperative day 1 as opposed to VG (-7.56 ± 15.89 mL/min/1.73 m<sup>2</sup> <i>vs</i> -0.21 ± 11.12 mL/min/1.73 m<sup>2</sup>; <i>p</i> = 0.015). The intraoperative blood loss, need for blood transfusion, postoperative change in hemoglobin rates, readmission, and renal function at 6 months in the VG and RG were comparable. <b><i>Conclusions:</i></b> The Veriset application instead of renorrhaphy led to reduced WIT, decreased console time, and early return of renal function with no significantly increased rate of complications.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hriday P Bhambhvani, Adithya Balasubramanian, Justin Lee, Richard Berman, Ojas Shah
{"title":"Prediction of Sepsis after Endourologic Kidney Stone Surgery: A Machine Learning Approach.","authors":"Hriday P Bhambhvani, Adithya Balasubramanian, Justin Lee, Richard Berman, Ojas Shah","doi":"10.1089/end.2024.0922","DOIUrl":"https://doi.org/10.1089/end.2024.0922","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Sepsis secondary to urinary tract infection after kidney stone surgery is associated with considerable morbidity. Limited research examines the use of hemoglobin A1c (HbA1c) to predict postoperative sepsis after endourologic procedures. We developed a machine learning (ML) model trained on demographic and clinical data to predict postoperative sepsis and better identify patients requiring preoperative optimization. <b><i>Methods:</i></b> Patients undergoing ureteroscopy, shockwave lithotripsy, or percutaneous nephrolithotomy at a tertiary care center were identified. Postoperative sepsis was defined as Systemic Inflammatory Response Syndrome (SIRS) scores ≥2. Five supervised ML models were developed: elastic-net penalized logistic regression, random forest, neural network, support vector machine, and naïve Bayes. The dataset was partitioned into training (80%) and testing (20%) sets; fivefold cross-validation was employed. Models were assessed for accuracy, discrimination via area under the receiver operating characteristic curve (AUCROC), calibration, and Brier score on the hold-out test set. <b><i>Results:</i></b> A total of 382 patients with complete data from a total cohort of 2,938 patients undergoing stone surgery from 2020 to 2023 were included with a mean age of 59.9 years (standard deviation [SD] ±14.9). Mean HbA1c was 6.34% (SD ±1.39). 15.2% (58/382) of patients in the study group developed postoperative sepsis, however the overall sepsis rate was 3.1% in the total cohort. Random forest modeling achieved the best performance in the hold-out test set with 91% accuracy, 0.88 AUCROC, calibration slope of 1.26, calibration intercept of -0.21, and Brier score of 0.09. The five most important urosepsis predictors, in descending order, were preoperative hemoglobin, HbA1c, stone size, length of surgery, and body mass index. The random forest model may be accessed at https://urol.shinyapps.io/sepsis_predict/. <b><i>Conclusions:</i></b> A random forest model performed well in predicting sepsis after kidney stone surgery. Our model may help guide preoperative surgical optimization and planning as well as postoperative monitoring, pending further validation.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brett A Johnson, Jonathan D Harper, Yu-Lun Liu, Hussein R Al-Khalidi, Hal D Kominsky, Rebecca D McCune, Alana C Desai, Ziya Kirkali, Charles D Scales, Naim M Maalouf
{"title":"Unplanned Health Care Utilization after Ureteroscopy with Ureteral Stenting: Results from the Study to Enhance Understanding of Stent-Associated Symptoms Cohort.","authors":"Brett A Johnson, Jonathan D Harper, Yu-Lun Liu, Hussein R Al-Khalidi, Hal D Kominsky, Rebecca D McCune, Alana C Desai, Ziya Kirkali, Charles D Scales, Naim M Maalouf","doi":"10.1089/end.2024.0805","DOIUrl":"https://doi.org/10.1089/end.2024.0805","url":null,"abstract":"<p><p><b><i>Background:</i></b> Urinary stone disease (USD) often necessitates ureteroscopy with ureteral stenting. We assessed the frequency and risk factors associated with unplanned health care utilization related to ureteroscopy with ureteral stenting within 30 postoperative days, using data from the STudy to Enhance uNderstanding of sTent-associated Symptoms (STENTS), a prospective multicenter observational cohort study. <b><i>Methods:</i></b> Demographic, medical, surgical, and postoperative data were collected prospectively across four clinical centers for participants undergoing ureteroscopy for USD. Any utilization of health care (urgent care/emergency room or in-person clinical encounter) within 30 days was assessed for potential relationship to the stone procedure. We used univariable and multivariable logistic regression models to evaluate the associations between potential prespecified covariates and the primary outcome of unplanned encounter (UE). <b><i>Results:</i></b> A total of 484 participants (451 adults) underwent ureteroscopy (424 unilateral and 60 bilateral). Mean age was 49 years, and 47% were female. All postoperative clinical encounters within 30 days were reviewed to determine if they were unplanned and surgery related. Overall, 49 of the participants (10%) had at least one UE within 30 days, and 24/49 (49%) were an emergency room visit and/or hospitalization. Age, race, sex, and previous stone history were not statistically associated with a UE. Participants with a chronic pain condition were three times more likely to have a UE. Surgical duration, use of a ureteral access sheath, stent diameter, or irrigation method did not differ between the groups in a multivariable logistic model. <b><i>Conclusions:</i></b> The prevalence of unplanned health care utilization related to ureteroscopy and stenting for USD in our cohort was 10%. The presence of a chronic pain condition was an independent predictor of a UE. These findings may help identify patients at higher risk of utilizing health care resources following USD surgery and could enable proactive targeted interventions.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Effect of Using Automated Irrigation Systems on the Risk of Infectious Complications after Endoscopic Combined Intrarenal Surgery: A Retrospective Cohort Study\".","authors":"Emma M Waddell, Daniel A Wollin","doi":"10.1089/end.2025.0338","DOIUrl":"https://doi.org/10.1089/end.2025.0338","url":null,"abstract":"","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Letter:</i> The Role of Tumor Volume Ratio in Predicting Clinically Significant Prostate Cancer on Transperineal Biopsy.","authors":"Ibrahim Hacibey","doi":"10.1089/end.2025.0281","DOIUrl":"https://doi.org/10.1089/end.2025.0281","url":null,"abstract":"","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Qualkenbush, Yeonsoo S Lee, Amanda Kahn, Neda Qosja, Alex Hochwald, Amanda Myers, Andrew Zganjar, Ram Pathak, Raymond Pak
{"title":"Peritoneal Window Technique: A Novel Sutureless Technique to Decrease the Rate of Symptomatic Lymphocele after Robot-Assisted Radical Prostatectomy with Extended Pelvic Lymph Node Dissection.","authors":"Eric Qualkenbush, Yeonsoo S Lee, Amanda Kahn, Neda Qosja, Alex Hochwald, Amanda Myers, Andrew Zganjar, Ram Pathak, Raymond Pak","doi":"10.1089/end.2025.0093","DOIUrl":"https://doi.org/10.1089/end.2025.0093","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Robot-assisted radical prostatectomy (RARP) with extended pelvic lymph node dissection (PLND) represents the gold standard surgical treatment for high-risk localized prostate cancer. PLND carries the risk of lymphocele formation, which can lead to complications such as deep vein thrombosis (DVT), infection, and voiding dysfunction. Many techniques have been described to minimize lymphocele formation, yet no method has seen widespread use or been described as sutureless. The objective of this study is to describe the novel, sutureless peritoneal window (PWIN) technique and assess its efficacy in lymphocele prophylaxis for extended PLND. <b><i>Methods:</i></b> This was a retrospective review of patients with high-risk prostate cancer undergoing RARP with extended PLND by a single surgeon from 2018 to 2024. PLND was carried out in the usual manner with bipolar cautery. PWIN technique is performed by excising a 3 × 5 cm PWIN over the lymphadenectomy bed to maintain lymphatic communication with the abdominal cavity. The primary outcome was a comparison between the incidence of symptomatic lymphoceles (SLs) with PWIN <i>vs</i> standard technique. SLs were defined as lymphoceles presenting with pain, DVT, voiding dysfunction, or infectious symptoms. Patients with asymptomatic lymphoceles were excluded. <b><i>Results:</i></b> Our study included 199 patients who underwent RARP with extended PLND. There were 46 patients (23.1%) in the standard approach group and 153 patients (76.9%) in the PWIN group. We identified 5/46 (10.9%) SLs in the standard technique, which were significantly higher than the 3/153 (2.0%) observed in the PWIN group (p = 0.017). There was no difference between the standard and PWIN cohorts regarding symptomology or treatment of their lymphocele. <b><i>Conclusion:</i></b> This study describes a novel, sutureless PWIN technique that significantly decreases SL after extended PLND. This technique offers a practical, time-efficient, and cost-effective alternative for lymphocele prevention. Future prospective studies are warranted to validate these findings.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}