Journal of Exposure Science and Environmental Epidemiology最新文献

{"title":"Longitudinal association of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) exposure with lipid traits, in a healthy unselected population.","authors":"Yasrab N Raza, Julia S El-Sayed Moustafa, Xinyuan Zhang, Dongmeng Wang, Max Tomlinson, Mario Falchi, Cristina Menni, Ruth C E Bowyer, Claire J Steves, Kerrin S Small","doi":"10.1038/s41370-025-00773-3","DOIUrl":"10.1038/s41370-025-00773-3","url":null,"abstract":"<p><strong>Background: </strong>Perfluorooctanoic acid (PFOA) and Perfluorooctanesulfonic Acid (PFOS) are synthetic substances with long half-lives. Their presence is widespread and pervasive, and they are noted for their environmental persistence. Research has shown these chemicals to be associated with dyslipidaemia, although few studies have considered the long-term associations in the general population.</p><p><strong>Objectives: </strong>The aim of this study was to consider the longitudinal and cross-sectional associations with lipid phenotypes.</p><p><strong>Methods: </strong>We investigated the association of these chemicals with total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), and the total cholesterol: high-density lipoprotein ratio (TC:HDL), in a healthy unselected British population of twins (n = 2069), measured at three timepoints between 1996 and 2014.</p><p><strong>Results: </strong>Serum levels of PFOA and PFOS decreased over time during this period. We demonstrate longitudinal associations across serum levels of both PFOA and PFOS, finding positive associations with TC (PFOA:β = 0.51, p = 1.9e-07; PFOS:β = 0.24, p = 3.8e-05) and LDL (PFOA:β = 0.61, p = 1.7e-11; PFOS:β = 0.42, p = 1.6e-14), and consistent negative associations with HDL and PFOA (β = -0.12, p = 0.003) and PFOS (β = -0.25, p = <2e-16). We also observe cross-sectional associations of PFAS with lipids across all three timepoints.</p><p><strong>Impact: </strong>PFAS remain persistent in the environment, despite regulations, due to their structural properties, leaving humans open to exposure. There is less understanding of how chronic low exposure to these chemicals, particularly within an unselected population, may impact health outcomes. This study reports the longitudinal associations of PFOA and PFOS over an 18-year window with 5 lipid phenotypes, highlighting that despite falling serum levels, PFAS exposure may lead to hyperlipidaemia. We further investigate the cross-sectional associations across three timepoints to understand time-dependent effects, demonstrating associations persist. This work aids our understanding on the long-term effect of chronic PFAS exposure.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electricity inaccessibility across historically redlined and present-day disadvantaged areas in New York City","authors":"Alexander J. Northrop,&nbsp;Vivian Do,&nbsp;Perry E. Sheffield,&nbsp;Diana Hernández,&nbsp;Jane Clougherty,&nbsp;Joan A. Casey","doi":"10.1038/s41370-025-00767-1","DOIUrl":"10.1038/s41370-025-00767-1","url":null,"abstract":"Electricity is crucial in sustaining livelihoods from turning the lights on at night, keeping the refrigerator running to avoid food spoilage, and powering electricity-dependent durable medical equipment such as nebulizers. Thus, electricity inaccessibility may result in adverse outcomes. Like other environmental burdens, electricity inaccessibility may be socially patterned, with disproportionate occurrence in racially and economically marginalized communities. To evaluate the 2017-2019 distribution of electricity inaccessibility – defined as power outages and energy insecurity – across historical and present-day measures of community racial disadvantage in New York City (NYC). We measured power outages with NYC 311 outage call reports and the System Average Interruption Frequency Index (SAIFI). We calculated energy insecurity as monthly average energy use, leveraging data from the New York State Energy Research and Development Authority. These three electricity inaccessibility metrics were estimated within both historical Home Owners’ Loan Corporation (HOLC) graded areas (A, ‘best’ through D, ‘redlined’) and present-day racial and economic Index of Concentrations at the Extremes (ICE) census tracts quartiles. Our study covered 396 HOLC areas and 2218 census tracts in NYC. Historically A-graded areas had fewer 311 outage calls and lower SAIFI. Additionally, the rate of 311 outage calls in the present-day most disadvantaged census tracts was nearly six times that of the most privileged tracts. Persistently disadvantaged areas (i.e., both poor HOLC grade and high ICE) had more power outages than consistently advantaged areas. However, the present-day most disadvantaged census tracts still had more power outages than persistently disadvantaged areas.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 5","pages":"848-858"},"PeriodicalIF":4.7,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perfluorooctanoic acid serum concentrations and half-lives in a community exposed to contaminated drinking water in New York State","authors":"Elizabeth L. Lewis-Michl,&nbsp;Steven P. Forand,&nbsp;Wan-Hsiang Hsu,&nbsp;Sanghamitra S. Savadatti,&nbsp;Ming Liu,&nbsp;June Moore,&nbsp;Qian Wu,&nbsp;Elizabeth J. Mullin,&nbsp;Kenneth M. Aldous","doi":"10.1038/s41370-025-00769-z","DOIUrl":"10.1038/s41370-025-00769-z","url":null,"abstract":"Investigations during 2014–2016 in two communities in New York State showed perfluorooctanoic acid (PFOA) in a public system serving 3800 residents (Hoosick Falls) averaging 534 ppt and in a smaller system serving 200 residents (Petersburgh) averaging 92.5 ppt. Bottled water (2015–2016) was provided until filtration brought PFOA levels to non-detectable (2016–2017). The New York State Department of Health (NYSDOH) sought to address community questions about exposures and evaluate reductions in serum concentrations. NYSDOH tested serum PFOA in 2016 just after drinking water exposure mitigation and again in 2018. Descriptive statistics for serum PFOA by sex, age, length of residence, and water consumption were evaluated using multiple regression, and half-lives were estimated. Using the serum PFOA GM and median for tests occurring within 3 months of exposure mitigation (N = 1121) (47.5, 54.2) produced serum to water ratios of 89.0 and 101.6. A total of 1573 Hoosick Falls public water consumers (337","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 3","pages":"403-413"},"PeriodicalIF":4.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personal care products exposure patterns and prostate cancer: evidence from a case-control study in Mexico City.","authors":"Luisa Torres-Sánchez, Jesús Gibran Hernández-Pérez, David S Lopez, Sara Romero-Romero, Lizbeth López-Carrillo, Mauricio Rodríguez-Dorantes, Ruth Argelia Vázquez-Salas","doi":"10.1038/s41370-025-00772-4","DOIUrl":"https://doi.org/10.1038/s41370-025-00772-4","url":null,"abstract":"<p><strong>Background: </strong>Personal care products (PCPs) use has been associated with a high risk of hormone-sensitive cancers in women. However, this association is poorly understood in hormone-sensitive cancers in men.</p><p><strong>Objective: </strong>To investigate the association between PCPs use and prostate cancer (PC) and PC histological differentiation in men from Mexico City.</p><p><strong>Methods: </strong>We analyzed the information from 400 histologically confirmed incident PC cases and 801 population controls matched by age (±5 y). The usage frequency (daily, weekly, or less, and non-use) of deodorant, body lotion, shampoo, perfume, and shaving or after-shaving products was evaluated based on a structured questionnaire. Using the K-means approach, we selected three patterns according to the usage frequency and number of PCPs used: high, intermediate, and low. Multivariable non-conditional logistic regression models adjusted by selected confounders were conducted to estimate the association between the use of PCPs (patterns, individual products, and number of products used daily) and PC, as well as PC histological differentiation.</p><p><strong>Results: </strong>Compared to the low exposure pattern, the high (OR: 2.6 95% CI: 1.8-3.8) and intermediate (OR: 1.3 95% CI: 1.0-1.8) PCPs patterns were associated with higher odds of PC. Similarly, the intermediate exposure pattern was significantly associated with poorly differentiated PC (OR: 1.8 95% CI: 1.1-2.9). The daily use of perfume was the most consistent PCP associated with PC (OR _{high vs. low}: 1.9 95% CI: 1.3-2.8; p for trend = 0.001) and PC poor differentiation (OR: 2.0, 95% CI: 1.1-3.6; p for trend = 0.013). In addition, a dose-response relationship was observed with the number of personal care products used daily.</p><p><strong>Impact statement: </strong>This study provided evidence that high exposure to personal care products (PCPs) is associated with prostate cancer. Our findings are consistent with those observed regarding hormone-sensitive female cancer and suggest the potential contribution of PCPs to prostatic carcinogenesis.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Reconstructing individual-level exposures in cohort analyses of environmental risks: an example with the UK Biobank","authors":"Jacopo Vanoli,&nbsp;Malcolm N. Mistry,&nbsp;Arturo De La Cruz Libardi,&nbsp;Pierre Masselot,&nbsp;Rochelle Schneider,&nbsp;Chris Fook Sheng Ng,&nbsp;Lina Madaniyazi,&nbsp;Antonio Gasparrini","doi":"10.1038/s41370-025-00771-5","DOIUrl":"10.1038/s41370-025-00771-5","url":null,"abstract":"","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 4","pages":"692-692"},"PeriodicalIF":4.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12234351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between indoor air exposures and cognitive test scores among university students in classrooms with increased ventilation rates for COVID-19 risk management","authors":"Sandra Dedesko,&nbsp;Joseph Pendleton,&nbsp;Anna S. Young,&nbsp;Brent A. Coull,&nbsp;John D. Spengler,&nbsp;Joseph G. Allen","doi":"10.1038/s41370-025-00770-6","DOIUrl":"10.1038/s41370-025-00770-6","url":null,"abstract":"Past work demonstrating an association between indoor air quality and cognitive performance brought attention to the benefits of increasing outdoor air ventilation rates beyond code minimums. These code minimums were scrutinized during the COVID-19 pandemic for insufficient ventilation and filtration specifications. As higher outdoor air ventilation was recommended in response, questions arose about potential benefits of enhanced ventilation beyond infection risk reduction. This was investigated by examining associations between indoor carbon dioxide concentrations, reflective of ventilation and building occupancy, and cognitive test scores among graduate students attending lectures in university classrooms with infection risk management strategies, namely increased ventilation. Post-class cognitive performance tests (Stroop, assessing inhibitory control and selective attention; Arithmetic, assessing cognitive speed and working memory) were administered through a smartphone application to participating students (54 included in analysis) over the 2022–2023 academic year in classrooms equipped with continuous indoor environmental quality monitors that provided real-time measurements of classroom carbon dioxide concentrations. Temporally and spatially paired exposure and outcome data was used to construct mixed effects statistical models that examined different carbon dioxide exposure metrics and cognitive test scores. Model estimates show directionally consistent evidence that higher central and peak classroom carbon dioxide concentrations, indicative of ventilation and occupancy, are associated with lower cognitive test scores over the measured range included in analysis ( ~ 440–1630 ppm). The effect estimates are strongest for 95th percentile class carbon dioxide concentrations, representing peak class carbon dioxide exposures.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 4","pages":"661-671"},"PeriodicalIF":4.7,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review","authors":"Adrian Goldsworthy,&nbsp;Liam A. O’Callaghan,&nbsp;Ciara Blum,&nbsp;Jarod Horobin,&nbsp;Lotti Tajouri,&nbsp;Matthew Olsen,&nbsp;Natalia Van Der Bruggen,&nbsp;Simon McKirdy,&nbsp;Rashed Alghafri,&nbsp;Oystein Tronstad,&nbsp;Jacky Suen,&nbsp;John F. Fraser","doi":"10.1038/s41370-025-00766-2","DOIUrl":"10.1038/s41370-025-00766-2","url":null,"abstract":"The human bioaccumulation of micro- and nano-plastics (MNPs) is increasingly being recognised in the aetiology and pathophysiology of human disease. This systematic scoping review aims to provide a comprehensive investigation of studies examining the impacts of MNPs on the human cardiovascular system. Five databases (PubMed, SCOPUS, CINAHL, Web of Science and EMBASE) were systematically searched. Forty-six articles were identified, 13 of which investigated the presence of MNPs within the human cardiovascular system, including atherosclerotic plaques, saphenous vein tissue, thrombi and venous blood. The effect of MNPs on cell lines suggest MNPs are cytotoxic, immunotoxic, and genotoxic. The findings of this review, when evaluated together with additional studies utilising animal models, suggest MNPs may contribute to global cardiovascular morbidity and mortality. In particular, the ability of MNPs to induce endothelial damage, oxy-LDL formation, foam cell development and apoptosis, as well as to alter the clotting cascade, has potential implications for vascular diseases. In addition, MNPs may play a role in the aetiology and progression of congenital heart abnormalities, infective pathologies and cardiomyopathies. Despite an increasing awareness of the ability for MNPs to result in cardiovascular disease and dysfunction, a limited amount of research has been conducted to date characterising the presence of MNPs in the human cardiovascular system. Reseach is required to understand the extent of this rapidly emerging issue and to develop strategies that will support clinicians to appropriately manage and educate their patients in the future.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 5","pages":"746-769"},"PeriodicalIF":4.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhalable microplastics and plastic additives in the indoor air of chemical laboratories","authors":"Joel D. Rindelaub,&nbsp;Gordon M. Miskelly","doi":"10.1038/s41370-025-00768-0","DOIUrl":"10.1038/s41370-025-00768-0","url":null,"abstract":"While recognition of airborne microplastics is increasing, there are still limited data on the microplastics within the aerosol size fractions most relevant to human inhalation (PM10 and PM2.5). Additionally, there are concerns that many of the additives used in plastic formulations have endocrine-disrupting properties, which could increase the hazards associated with microplastic exposure. To better understand the toxicological risks associated with airborne microplastics, more data are urgently needed on the mass concentrations of both microplastics and the related chemical additives in the air we breathe. Inhalation exposure to plastic-related species is currently uncertain in chemical laboratory workplaces. Using a Pyrolysis Gas Chromatography Mass Spectrometry (Pyr-GC/MS) based method, the airborne mass concentrations of both polymeric material and small molecule plastic additives were determined in inhalable air from two indoor locations. This method represents a fast, direct technique that can be used to better standardize airborne microplastic measurements. The PM2.5 and PM10 concentrations of seven different polymers were determined, with average plastic concentrations of 0.51 μg m−3 for the PM2.5 samples and 1.14 µg m−3 for the PM10 samples. Polycarbonate, polyvinylchloride, and polyethylene had the highest airborne concentrations in the inhalable fraction of air. Simultaneously, the airborne concentrations of plastic additives were determined, with phthalate-based plasticizers having an average concentration of 334 ng m−3 across all air samples.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 5","pages":"785-791"},"PeriodicalIF":4.7,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the relationship between space-time behaviours and personal noise exposure using isotemporal substitution models in the Grand Paris area.","authors":"Giovanna Fancello, Arnaud Can, Pierre Aumond, Sanjeev Bista, Basile Chaix","doi":"10.1038/s41370-025-00765-3","DOIUrl":"https://doi.org/10.1038/s41370-025-00765-3","url":null,"abstract":"<p><strong>Background: </strong>The individual exposure to environmental noise in cities is usually assessed at the residential neighbourhood level with static, year-averaged strategic maps. This representation may underestimate noise exposure, given the mobility of individuals within the city and proximate sources of exposure.</p><p><strong>Objective: </strong>Our study employs high-resolution sensor analysis to observe how personal noise exposure differs from modelled noise map metrics, identify socioeconomical and behavioural determinants of exposure, and explore the impact of reallocating certain behaviours to others on daily personal noise exposure (L_Aeq,24h).</p><p><strong>Method: </strong>Data on daily activities of 259 participants of the MobiliSense cohort living in the metropolitan area of Paris were collected between 2018 and 2020. Participants were equipped of a personal monitor for sound pressure, and of a GPS receiver and an accelerometer. Modes of transport were collected during a mobility survey.</p><p><strong>Results: </strong>Results showed that noise exposure based on personal monitoring during space-time behaviours differed from modelled noise levels at residence. Participants were exposed to values below the recommended critical value for health of 55 dB(A) in urban areas in only 36% of the days. Individual socioeconomic characteristics and residential factors explained very little variance in personal noise exposure. Noise exposure varied among performed activities and transport modes, with public transport associated with the highest sound levels. While time spent in the underground public transport was on average 1.4% of the total daily time-budget, it contributes on average to 9.5% of the daily noise dose.</p><p><strong>Impact: </strong>This research reveals that individual mobility behaviours significantly influence daily noise exposure in urban environments. By analysing how people move throughout their day, we found that traditional static assessments, limited to residential noise, underestimate actual exposure. Notably, despite limited time spent in it (1,4%), underground transport contributed substantially to daily noise (9.5%). Furthermore, participants experienced noise levels below recommended health thresholds in only 36% of days. These findings underscore the need for policy changes that prioritize walkable cities and minimize commuting time, alongside the design of \"quiet areas\" within urban spaces for recovering from the city noise stress.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacts of night market on indoor air quality and lung function of children in nearby households.","authors":"Jia Lin Zhang, Tsu-Nai Wang, Pei-Chen Lin, Kuan-Ting Lin, Yu-Han Chen, Jyun-Min Jhang, Ting-Ching Yao, Yuan-Chung Lin, Pei-Shih Chen","doi":"10.1038/s41370-025-00755-5","DOIUrl":"10.1038/s41370-025-00755-5","url":null,"abstract":"<p><strong>Background: </strong>Night markets-a unique element of Asian culture-involve various cooking methods and combustion, generating air pollutants with adverse health effects. However, there is no scientific literature on whether air pollutants from night markets affect indoor air quality and the lung function of children in nearby households.</p><p><strong>Objective: </strong>We evaluated the impacts of night market, specifically market opening days and household distance from the market, on indoor air quality and the lung function of children in nearby households.</p><p><strong>Methods: </strong>Using real-time monitoring equipment, we measured concentrations of particulate matter (PM)₁, PM_2.5, PM₁₀, carbon dioxide (CO₂), carbon monoxide (CO), nitrogen dioxide, sulfur dioxide (SO₂), ozone, total volatile organic compound (TVOC), airborne bacteria, and fungi in 58 households located near a night market. Additionally, we assessed the lung function values of children living in these households.</p><p><strong>Results: </strong>PM₁ and PM_2.5 concentrations were significantly higher during opening days than during closing days. The lung function values for children were significantly lower in households located ≤595 m from the market (near group) than in those located >595 m from the market (far group). Higher CO₂, CO, SO₂, TVOCs, and PM₁₀ concentrations and poor lung function were observed in children in the near group.</p><p><strong>Impact statement: </strong>PM₁ and PM_2.5 concentrations were significantly higher during opening days of the night market than during closing days. Children residing near the night market (≤595 m) exhibited significantly lower lung function values than those living in houses located >595 m from the market.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}