Journal of Exposure Science and Environmental Epidemiology最新文献

筛选
英文 中文
Disparities in exposure to concentrated animal feeding operations (CAFOs) and other animal feeding operations across multiple states in USA. 美国多个州对集中动物饲养操作(cafo)和其他动物饲养操作的暴露差异。
IF 4.7 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-06-06 DOI: 10.1038/s41370-025-00783-1
Ji-Young Son, Brandon M Lewis, Michelle L Bell
{"title":"Disparities in exposure to concentrated animal feeding operations (CAFOs) and other animal feeding operations across multiple states in USA.","authors":"Ji-Young Son, Brandon M Lewis, Michelle L Bell","doi":"10.1038/s41370-025-00783-1","DOIUrl":"10.1038/s41370-025-00783-1","url":null,"abstract":"<p><strong>Background: </strong>Animal feeding operations (AFOs), including concentrated animal feeding operations (CAFOs), pose significant environmental degradation and health risks. These facilities are often disproportionately located in disadvantaged communities, however, findings are inconsistent.</p><p><strong>Objective: </strong>We investigated disparities in AFO/CAFO exposure across seven US states, focusing on variables related to environmental justice (EJ) and at-risk populations.</p><p><strong>Methods: </strong>We linked AFO/CAFO data from seven states (Iowa, North Carolina, Pennsylvania, South Carolina, Texas, Virginia, and Wisconsin) to ZIP code-level census variables. We assessed exposure by calculating area-weighted number of AFO/CAFO within 15 km buffers and categorized ZIP codes into no, low, medium, and high exposure groups. Our analysis compared the spatial distributions of AFO/CAFO exposure and variables related to EJ and at-risk populations by exposure intensity.</p><p><strong>Results: </strong>We found differences in the distributions of AFO/CAFO exposure and variables related to EJ and at-risk populations among states. In some states (e.g., North Carolina, Pennsylvania), AFOs/CAFOs were densely clustered in specific areas, while in others (e.g., Iowa, Wisconsin), they were more evenly distributed. We found disproportionate exposure to AFO/CAFO in disadvantaged communities such as communities with high percentages of racial/ethnic minority persons and low socioeconomic status in some states, whereas other states showed different patterns. Trends varied by state, with some showing increasing Non-Hispanic Black and Hispanic populations with higher exposure (e.g., North Carolina), while others showed opposite trends (e.g., Pennsylvania). Education, poverty, and income levels also varied, with some states (e.g., North Carolina, South Carolina) showing higher poverty rates, lower education level, and lower incomes in higher exposure groups and other states showing reverse trends (e.g., Wisconsin).</p><p><strong>Impact: </strong>This study investigated disparities in AFO/CAFO exposure across seven US states. We applied an advanced exposure metric and considered multiple variables to capture diverse aspects of environmental injustice and disadvantaged communities. Our findings across multiple states provide valuable insights that can inform policy development and help mitigate exposure disparities across various populations and locations.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the association between groundwater contaminants and hypertension risk in India: a machine learning-based analysis. 调查印度地下水污染物与高血压风险之间的关系:基于机器学习的分析。
IF 4.1 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-06-04 DOI: 10.1038/s41370-025-00776-0
Sourav Biswas, Aparajita Chattopadhyay, Kathrin Schilling, Ayushi Das
{"title":"Investigating the association between groundwater contaminants and hypertension risk in India: a machine learning-based analysis.","authors":"Sourav Biswas, Aparajita Chattopadhyay, Kathrin Schilling, Ayushi Das","doi":"10.1038/s41370-025-00776-0","DOIUrl":"https://doi.org/10.1038/s41370-025-00776-0","url":null,"abstract":"<p><strong>Background: </strong>One-fourth of Indians are hypertensive, and the majority relies on groundwater for drinking. But the role of groundwater physicochemical properties and contamination in hypertension remains understudied.</p><p><strong>Objective: </strong>The study investigates the association between physicochemical groundwater characteristics andcontaminants and hypertension risk in India.</p><p><strong>Data: </strong>This study used data from the fifth round of the National Family Health Survey (NFHS-5 collected 2019-2021), including health, socio-demographics, and food and dietary information (n = 712,666 individuals). The physicochemical characteristics of groundwater data were derived from the Central Groundwater Board (CGWB, 2019-2021). This groundwater data from raster maps was linked to NFHS-5 records using cluster shapefiles and merging them with individual records via cluster IDs.</p><p><strong>Methods: </strong>Bivariate and multivariable regressions were used to identify factors associated with hypertension at the individual level. Moran's I statistics, Local Indicator of Spatial Association (LISA) cluster maps, and the Spatial Error Model (SEM) were used at district levels to investigate the spatial association. Machine learning models, including Artificial Neural Networks (ANN), Random Forest and Extreme Gradient Boosting (XGBoost), were used to predict hypertension risk zones.</p><p><strong>Results: </strong>Physicochemical drinking water composition is a key factor in hypertension risk. Elevated groundwater pH (>8.5, Adjusted Odds Ratio (AOR): 2.12), electrical conductivity (>300 μS/cm, AOR: 1.06), sulphate (>200 mg/L,  AOR: 1.16), arsenic (>0.01 mg/L, AOR: 1.09), nitrate (>45 mg/L, AOR: 1.07), and magnesium (>30 mg/L, AOR: 1.03) are associated to higher odds of hypertension. The Random Forest model demonstrated the highest predictive performance, with a coefficient of determination (R²) of 0.9970, mean absolute error (MAE) of 0.0012, and mean squared error (MSE) of 0.0077. It effectively identified high-risk zones in the northwestern (Delhi, Punjab, Haryana, and Rajasthan) and eastern (West Bengal and Bihar) regions of India.</p><p><strong>Impact: </strong>This study highlights how important groundwater quality is in determining the incidence of hypertension, pointing to groundwater physicochemical properties and contaminants such as electrical conductivity, sulphate, arsenic, nitrate, and magnesium as essential factors. Our research is the first of its kind to comprehensively map hypertension risk zones using machine learning models and geospatial analysis. The findings highlight that water quality is a modifiable risk factor, reinforcing the need for improved drinking water supply systems, regular water quality testing, and targeted interventions in high-risk regions. This study emphasizes the importance of intersectoral collaborations to enhance public health outcomes.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of climatic factors with pregnancy loss in Nicosia, Cyprus 塞浦路斯尼科西亚气候因素与妊娠损失的关系。
IF 4.7 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-05-22 DOI: 10.1038/s41370-025-00781-3
Aashna Pranav Shah, Souzana Achilleos, Veronica A. Wang, Michael Leung, Marc G. Weisskopf, Theopisti Kyprianou, Petros Koutrakis, Stefania Papatheodorou
{"title":"Associations of climatic factors with pregnancy loss in Nicosia, Cyprus","authors":"Aashna Pranav Shah,&nbsp;Souzana Achilleos,&nbsp;Veronica A. Wang,&nbsp;Michael Leung,&nbsp;Marc G. Weisskopf,&nbsp;Theopisti Kyprianou,&nbsp;Petros Koutrakis,&nbsp;Stefania Papatheodorou","doi":"10.1038/s41370-025-00781-3","DOIUrl":"10.1038/s41370-025-00781-3","url":null,"abstract":"While ambient climatic factors are linked to adverse pregnancy outcomes, only a few studies examine the risk of pregnancy loss. This study aims to examine the effects of climatic factors on pregnancy loss in Nicosia, Cyprus, an area that is highly affected by climate change. Birth registry data obtained from maternity units in Nicosia from 2014–2019 were linked with daily meteorological and traffic pollution data (minimum and maximum temperature, °C; relative humidity [RH], %; and nitrogen dioxide [NO2], μg/m3). We also estimated other climatic factors from the obtained data (mean weekly temperature, standard deviation of weekly temperature and RH [temperature and RH variability], and heat index [HI]). We used a novel variation of time-series design and distributed lag models adjusting for secular trends and air pollution to explore the association between climatic factors and weekly live-birth identified conceptions (LBICs), to indirectly estimate pregnancy losses. There were 26,382 live births over the study period, with an average weekly LBICs of 84.7( ± 12.2). We found an association between exposure to higher temperature between gestation weeks 0–9 and pregnancy loss, with the strongest association in weeks 0–1. Specifically, for a 5°C increase in mean week 0–1 temperature, 3.17 (95% Confidence Interval [CI]: 1.06–5.28) additional conceptions would result in pregnancy losses. A similar effect during early pregnancy was found for exposure to minimum and maximum temperature, HI, and RH. Furthermore, we found that temperature variability may have an impact in later weeks during pregnancy, with the strongest estimate in week 26 (6.70 [95% CI: 0.78–13.21] losses per 5 °C increase in standard deviation of weekly temperature). Similar results were observed for RH variability. This research investigates the link between climatic factors and pregnancy loss in Nicosia, Cyprus, a region experiencing rising temperatures and humidity levels. By analyzing live birth data using a novel time-series approach, the study finds that higher temperatures and humidity levels are associated with increased pregnancy loss, particularly in early gestation. These findings underscore the need for targeted public health interventions, such as heat warning systems, to mitigate the impact of climate change on vulnerable populations. As climate change escalates, understanding these associations is crucial for developing effective strategies to protect maternal and fetal health.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 5","pages":"831-838"},"PeriodicalIF":4.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between neighborhood greenery and birth outcomes in a North Carolina cohort 北卡罗莱纳队列中社区绿化与出生结果之间的关系。
IF 4.7 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-05-21 DOI: 10.1038/s41370-025-00780-4
Wei-Lun Tsai, Thomas J. Luben, Kristen M. Rappazzo
{"title":"Associations between neighborhood greenery and birth outcomes in a North Carolina cohort","authors":"Wei-Lun Tsai,&nbsp;Thomas J. Luben,&nbsp;Kristen M. Rappazzo","doi":"10.1038/s41370-025-00780-4","DOIUrl":"10.1038/s41370-025-00780-4","url":null,"abstract":"Higher levels of neighborhood greenery have been associated with improved birth outcomes. However, many studies use metrics relying on vegetation density and are not able to distinguish types of greenery or spatial context, which may result in variation in potential benefits. We examined relationships between term low birth weight (TLBW) and preterm birth (PTB), and different types of neighborhood greenery (i.e., tree cover, herbaceous cover, and aggregate greenery) within various spatial contexts (i.e., Euclidean distance and network distance-based buffers, and busy roadways to represent overall, street, and near-road greenery). North Carolina birth registry data from 2003 to 2015 were used to create a singleton live birth cohort and linked to greenery metrics from EnviroAtlas. Logistic regression models were used to estimate OR (95%CI) for associations between greenery metrics and TLBW (&lt;2500 g) or PTB (&lt;37 weeks gestational age) adjusting for potential confounders. Analyses were stratified by race/ethnicity, as many studies report potential differences in proximity to greenery across these groups. We observed modest associations between multiple measures of neighborhood greenery and TLBW and PTB. Most of our results indicated a decreased odds of adverse birth outcomes with increasing levels of neighborhood greenery, but some associations showed increased odds of adverse birth outcomes. We observed the strongest associations between overall aggregate greenery with TLBW (0.967 [0.939, 0.996]) and near-road tree cover with PTB (0.985 [0.971, 0.999]). We also observed unexpected associations between increased greenway density and TLBW among non-Hispanic Black mothers (1.181 [1.049, 1.326]). In contrast, we observed a decreased odds of PTB associated with increased greenway density for non-Hispanic white mothers (0.926 [0.871, 0.983]). We examined relationships between adverse birth outcomes and different types of neighborhood greenery, generally finding decreased odds of adverse birth outcomes with increasing levels of neighborhood greenery, with the strongest associations between aggregate greenery based on the Euclidean distance and decreased odds of term low birth weight. However, we also observed unexpected associations with increased greenway density and increased term low birth weight among non-Hispanic Black mothers. These results highlight the importance of considering the ways greenspace may or may not benefit some communities and will be important in guiding future efforts to increase instorative value or restore neighborhood greenspaces.","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 5","pages":"821-830"},"PeriodicalIF":4.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of volatile organic compound (VOC) emissions from desktop 3D printers and associated health implications. 桌面3D打印机的挥发性有机化合物(VOC)排放及其对健康的影响。
IF 4.1 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-05-08 DOI: 10.1038/s41370-025-00778-y
Danielle A Baguley, Gareth S Evans, Delphine Bard, Paul S Monks, Rebecca L Cordell
{"title":"Review of volatile organic compound (VOC) emissions from desktop 3D printers and associated health implications.","authors":"Danielle A Baguley, Gareth S Evans, Delphine Bard, Paul S Monks, Rebecca L Cordell","doi":"10.1038/s41370-025-00778-y","DOIUrl":"https://doi.org/10.1038/s41370-025-00778-y","url":null,"abstract":"<p><strong>Background: </strong>Three-dimensional (3D) printing is a technique by which materials are continually added in layers to form structures. The technique has grown in popularity over the past decade and affordable desktop 3D printers are now widely used in schools, universities, businesses, and hospitals.</p><p><strong>Objective: </strong>Understanding the types of chemical emissions from these 3D printers and their potential health effects is essential to safely use this technology.</p><p><strong>Methods: </strong>A scoping literature review on volatile organic compound (VOC) emissions from resin-bed and filament 3D printers has been conducted. Most of the published research has focused on emissions from filament 3D printers.</p><p><strong>Results: </strong>VOC emissions from resin 3D printers have been reported mostly as carbonyl compounds or methacrylate monomers. Filament VOC emissions are more varied in composition reflecting the constituents in the filaments used in this printer. The published research reported that the airborne concentrations of specific VOCs from 3D desktop printers fell below the HSE British workplace exposure limits (WELs). This may suggest that VOC emissions from these printers do not present a risk to occupational health. However, caution is required in reaching this conclusion because most of these studies quantified specific VOC emissions using methods different to those required by workplace regulatory standards. Other exposure circumstances, such as the effect of total VOC emissions, need to be considered, particularly for vulnerable groups, including individuals with respiratory disease, the elderly, or young children. Variables that could increase exposure and risks to health include long print times, multiple 3D printers, and poor ventilation. Research on the VOC emissions from resin 3D printers is required using experimental emission chambers.</p><p><strong>Impact: </strong>The research discussed in this review focused on VOC emissions from desktop 3D printers and the potential health impacts associated with exposure to these compounds. The review identifies circumstances when people may be exposed to 3D printer emissions for which no regulatory exposure limits apply. This circumstance is especially relevant to people working in small businesses and organisations and to vulnerable people, such as the young, elderly and those with pre-existing lung disease. Raising awareness of these potential health concerns from 3D printer emissions can help to inform actions to mitigate exposure, through policy and behavioural changes, as well as engineering control measures. To our knowledge, this is the first review discussing studies of VOC emission from resin and popular filament 3D printers, including exposure risks and health outcomes.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can a single pollen measurement site provide exposure information for health research across an entire state? Results from a study of allergic-type asthma associated with thunderstorms (2007-2018). 一个单独的花粉测量点能否为整个州的健康研究提供暴露信息?雷暴相关的过敏性哮喘研究结果(2007-2018)。
IF 4.1 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-05-05 DOI: 10.1038/s41370-025-00777-z
M Luke Smith, Richard F MacLehose, Jesse D Berman
{"title":"Can a single pollen measurement site provide exposure information for health research across an entire state? Results from a study of allergic-type asthma associated with thunderstorms (2007-2018).","authors":"M Luke Smith, Richard F MacLehose, Jesse D Berman","doi":"10.1038/s41370-025-00777-z","DOIUrl":"10.1038/s41370-025-00777-z","url":null,"abstract":"<p><strong>Background: </strong>Thunderstorm asthma is an increase in severe asthma following thunderstorm events during high pollen conditions. However, sparse pollen measurements hinder epidemiological research of this phenomenon.</p><p><strong>Objective: </strong>Is pollen measured at a single site predictive of thunderstorm asthma risk across a broad region?</p><p><strong>Methods: </strong>We conducted a meta-analysis to estimate thunderstorm asthma risk on 19 city-level sites incorporating local weather and patient data but a single pollen site. We use meta-regression to explore effect modification by land cover and distance from pollen measurement location.</p><p><strong>Results: </strong>Meta-analysis showed no evidence of a state-wide thunderstorm asthma effect. Meta-regressions suggest that increased vegetation was associated with higher thunderstorm asthma risk with reduced risk at greater distances from pollen collection sites.</p><p><strong>Impact statement: </strong>The phenomenon of thunderstorm asthma in the U.S. remains poorly studied due to geographically sparse pollen collection sites. Using a 19-city study, we demonstrate that incorporating environmental characteristics, such as land cover of allergic-type pollen-producing grasslands and deciduous trees, can improve the prediction of thunderstorm asthma risk at far distances from pollen monitors. By increasing the precision of pollen estimates, we can improve the estimation of thunderstorm asthma human health risks and potentially optimize decisions for new pollen collection sites.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal association of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) exposure with lipid traits, in a healthy unselected population. 在未选择的健康人群中,全氟辛酸(PFOA)和全氟辛烷磺酸(PFOS)暴露与脂质特征的纵向关联
IF 4.1 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-04-24 DOI: 10.1038/s41370-025-00773-3
Yasrab N Raza, Julia S El-Sayed Moustafa, Xinyuan Zhang, Dongmeng Wang, Max Tomlinson, Mario Falchi, Cristina Menni, Ruth C E Bowyer, Claire J Steves, Kerrin S Small
{"title":"Longitudinal association of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) exposure with lipid traits, in a healthy unselected population.","authors":"Yasrab N Raza, Julia S El-Sayed Moustafa, Xinyuan Zhang, Dongmeng Wang, Max Tomlinson, Mario Falchi, Cristina Menni, Ruth C E Bowyer, Claire J Steves, Kerrin S Small","doi":"10.1038/s41370-025-00773-3","DOIUrl":"10.1038/s41370-025-00773-3","url":null,"abstract":"<p><strong>Background: </strong>Perfluorooctanoic acid (PFOA) and Perfluorooctanesulfonic Acid (PFOS) are synthetic substances with long half-lives. Their presence is widespread and pervasive, and they are noted for their environmental persistence. Research has shown these chemicals to be associated with dyslipidaemia, although few studies have considered the long-term associations in the general population.</p><p><strong>Objectives: </strong>The aim of this study was to consider the longitudinal and cross-sectional associations with lipid phenotypes.</p><p><strong>Methods: </strong>We investigated the association of these chemicals with total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), and the total cholesterol: high-density lipoprotein ratio (TC:HDL), in a healthy unselected British population of twins (n = 2069), measured at three timepoints between 1996 and 2014.</p><p><strong>Results: </strong>Serum levels of PFOA and PFOS decreased over time during this period. We demonstrate longitudinal associations across serum levels of both PFOA and PFOS, finding positive associations with TC (PFOA:β = 0.51, p = 1.9e-07; PFOS:β = 0.24, p = 3.8e-05) and LDL (PFOA:β = 0.61, p = 1.7e-11; PFOS:β = 0.42, p = 1.6e-14), and consistent negative associations with HDL and PFOA (β = -0.12, p = 0.003) and PFOS (β = -0.25, p = <2e-16). We also observe cross-sectional associations of PFAS with lipids across all three timepoints.</p><p><strong>Impact: </strong>PFAS remain persistent in the environment, despite regulations, due to their structural properties, leaving humans open to exposure. There is less understanding of how chronic low exposure to these chemicals, particularly within an unselected population, may impact health outcomes. This study reports the longitudinal associations of PFOA and PFOS over an 18-year window with 5 lipid phenotypes, highlighting that despite falling serum levels, PFAS exposure may lead to hyperlipidaemia. We further investigate the cross-sectional associations across three timepoints to understand time-dependent effects, demonstrating associations persist. This work aids our understanding on the long-term effect of chronic PFAS exposure.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfluorooctanoic acid serum concentrations and half-lives in a community exposed to contaminated drinking water in New York State 纽约州接触受污染饮用水的社区的全氟辛酸血清浓度和半衰期。
IF 4.7 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-04-17 DOI: 10.1038/s41370-025-00769-z
Elizabeth L. Lewis-Michl, Steven P. Forand, Wan-Hsiang Hsu, Sanghamitra S. Savadatti, Ming Liu, June Moore, Qian Wu, Elizabeth J. Mullin, Kenneth M. Aldous
{"title":"Perfluorooctanoic acid serum concentrations and half-lives in a community exposed to contaminated drinking water in New York State","authors":"Elizabeth L. Lewis-Michl,&nbsp;Steven P. Forand,&nbsp;Wan-Hsiang Hsu,&nbsp;Sanghamitra S. Savadatti,&nbsp;Ming Liu,&nbsp;June Moore,&nbsp;Qian Wu,&nbsp;Elizabeth J. Mullin,&nbsp;Kenneth M. Aldous","doi":"10.1038/s41370-025-00769-z","DOIUrl":"10.1038/s41370-025-00769-z","url":null,"abstract":"Investigations during 2014–2016 in two communities in New York State showed perfluorooctanoic acid (PFOA) in a public system serving 3800 residents (Hoosick Falls) averaging 534 ppt and in a smaller system serving 200 residents (Petersburgh) averaging 92.5 ppt. Bottled water (2015–2016) was provided until filtration brought PFOA levels to non-detectable (2016–2017). The New York State Department of Health (NYSDOH) sought to address community questions about exposures and evaluate reductions in serum concentrations. NYSDOH tested serum PFOA in 2016 just after drinking water exposure mitigation and again in 2018. Descriptive statistics for serum PFOA by sex, age, length of residence, and water consumption were evaluated using multiple regression, and half-lives were estimated. Using the serum PFOA GM and median for tests occurring within 3 months of exposure mitigation (N = 1121) (47.5, 54.2) produced serum to water ratios of 89.0 and 101.6. A total of 1573 Hoosick Falls public water consumers (337","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 3","pages":"403-413"},"PeriodicalIF":4.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personal care products exposure patterns and prostate cancer: evidence from a case-control study in Mexico City. 个人护理产品暴露模式与前列腺癌:来自墨西哥城病例对照研究的证据。
IF 4.1 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-04-16 DOI: 10.1038/s41370-025-00772-4
Luisa Torres-Sánchez, Jesús Gibran Hernández-Pérez, David S Lopez, Sara Romero-Romero, Lizbeth López-Carrillo, Mauricio Rodríguez-Dorantes, Ruth Argelia Vázquez-Salas
{"title":"Personal care products exposure patterns and prostate cancer: evidence from a case-control study in Mexico City.","authors":"Luisa Torres-Sánchez, Jesús Gibran Hernández-Pérez, David S Lopez, Sara Romero-Romero, Lizbeth López-Carrillo, Mauricio Rodríguez-Dorantes, Ruth Argelia Vázquez-Salas","doi":"10.1038/s41370-025-00772-4","DOIUrl":"https://doi.org/10.1038/s41370-025-00772-4","url":null,"abstract":"<p><strong>Background: </strong>Personal care products (PCPs) use has been associated with a high risk of hormone-sensitive cancers in women. However, this association is poorly understood in hormone-sensitive cancers in men.</p><p><strong>Objective: </strong>To investigate the association between PCPs use and prostate cancer (PC) and PC histological differentiation in men from Mexico City.</p><p><strong>Methods: </strong>We analyzed the information from 400 histologically confirmed incident PC cases and 801 population controls matched by age (±5 y). The usage frequency (daily, weekly, or less, and non-use) of deodorant, body lotion, shampoo, perfume, and shaving or after-shaving products was evaluated based on a structured questionnaire. Using the K-means approach, we selected three patterns according to the usage frequency and number of PCPs used: high, intermediate, and low. Multivariable non-conditional logistic regression models adjusted by selected confounders were conducted to estimate the association between the use of PCPs (patterns, individual products, and number of products used daily) and PC, as well as PC histological differentiation.</p><p><strong>Results: </strong>Compared to the low exposure pattern, the high (OR: 2.6 95% CI: 1.8-3.8) and intermediate (OR: 1.3 95% CI: 1.0-1.8) PCPs patterns were associated with higher odds of PC. Similarly, the intermediate exposure pattern was significantly associated with poorly differentiated PC (OR: 1.8 95% CI: 1.1-2.9). The daily use of perfume was the most consistent PCP associated with PC (OR <sub>high vs. low</sub>: 1.9 95% CI: 1.3-2.8; p for trend = 0.001) and PC poor differentiation (OR: 2.0, 95% CI: 1.1-3.6; p for trend = 0.013). In addition, a dose-response relationship was observed with the number of personal care products used daily.</p><p><strong>Impact statement: </strong>This study provided evidence that high exposure to personal care products (PCPs) is associated with prostate cancer. Our findings are consistent with those observed regarding hormone-sensitive female cancer and suggest the potential contribution of PCPs to prostatic carcinogenesis.</p>","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Reconstructing individual-level exposures in cohort analyses of environmental risks: an example with the UK Biobank 修正:重建环境风险队列分析中的个人水平暴露:以英国生物银行为例。
IF 4.7 3区 医学
Journal of Exposure Science and Environmental Epidemiology Pub Date : 2025-04-16 DOI: 10.1038/s41370-025-00771-5
Jacopo Vanoli, Malcolm N. Mistry, Arturo De La Cruz Libardi, Pierre Masselot, Rochelle Schneider, Chris Fook Sheng Ng, Lina Madaniyazi, Antonio Gasparrini
{"title":"Correction: Reconstructing individual-level exposures in cohort analyses of environmental risks: an example with the UK Biobank","authors":"Jacopo Vanoli,&nbsp;Malcolm N. Mistry,&nbsp;Arturo De La Cruz Libardi,&nbsp;Pierre Masselot,&nbsp;Rochelle Schneider,&nbsp;Chris Fook Sheng Ng,&nbsp;Lina Madaniyazi,&nbsp;Antonio Gasparrini","doi":"10.1038/s41370-025-00771-5","DOIUrl":"10.1038/s41370-025-00771-5","url":null,"abstract":"","PeriodicalId":15684,"journal":{"name":"Journal of Exposure Science and Environmental Epidemiology","volume":"35 4","pages":"692-692"},"PeriodicalIF":4.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12234351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信