Jurnal MedaliPub Date : 2022-12-12DOI: 10.30659/medali.4.3.56-62
Shella Indri Novianty, Arlina Nurhapsari, Anitalia Sukma Permata Sari
{"title":"EFFECT OF ASIATIC ACID ISOLATE ON DECREASING REACTIVE OXYGEN SPECIES (ROS) LEVELS IN MICE REVERSIBLE PULPITIS","authors":"Shella Indri Novianty, Arlina Nurhapsari, Anitalia Sukma Permata Sari","doi":"10.30659/medali.4.3.56-62","DOIUrl":"https://doi.org/10.30659/medali.4.3.56-62","url":null,"abstract":"Background: Pulpitis is a form of pulp inflammation that occurs due to the response of vascular connective tissue to a trauma or continuation of caries. During inflammation the release of Tumor Necrosis Factor Alpha (TNF- ) will regulate excess ROS. Reactive Oxygen Species (ROS) can damage cellular lipids that cause oxidative stress, cell or tissue damage in mice caused by ROS to be seen with malondhydehyde biomarker (MDA) donors. Asiatic acid is a natural antioxidant that is able to neutralize free radicals by suppressing oxidative stress. This study aims to determine the effect of asiatic acid isolates on the reduction of ROS levels in reversible pulpitis mouse models. Method: This type of research is an experimental laboratory in vivo, conducted by making pulpitis on the right and left teeth of the right and left jaws of 24 male Wistar rats who were treated in the form of a control group, Asiatic Acid 0.5%, 1% and 2%, then examined using elisa sandwich method Result: The One way anova test showed that the highest mean rank was the control group and the lowest was the Asiatic Acid group of 1%. The p value < 0.05, there was a significant difference in the concentration of Asiatic Acid isolates against the significant reduction in ROS levels in reversible pulpitis between the four groups. Post Hoc LSD (Least Significant Difference test in between control groups and 1%, 0.5% and 1% group, and 1% and 2% groups obtained p < 0.05 which means there is a significant difference in reactive oxygen species (ROS) levels in reversible pulpitis between the two groups . Conclusion: Asiatic Acid was able to reduce the amount of Reactive Oxygen Species (ROS) as seen from the parameters of Malondialdehyde antibodies (MDA) in male wistar mice that developed reversible pulpitis","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125402204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-12-12DOI: 10.30659/medali.4.3.1-5
R. Putranto, M. M. S. Abdurrohman, C. Grati
{"title":"EFFECTS OF CLAMSHELL (Amusium Pleuronectes) CHITOSAN EXTRACT ON THE INCREASE NUMBER OF OSTEOBLAST OF THE ALVEOLAR BONE UNDER PERIODONTITIS","authors":"R. Putranto, M. M. S. Abdurrohman, C. Grati","doi":"10.30659/medali.4.3.1-5","DOIUrl":"https://doi.org/10.30659/medali.4.3.1-5","url":null,"abstract":"Background: Background: The number of patients with periodontal disease in Indonesia is estimated to continue to increase yearly. 4.79% or 34614 people had healthy periodontal tissue, while 95.21% or 687715 people had unhealthy periodontal tissue. Clamshell waste containing chitosan can be utilized, considering that interest in sources of raw materials derived from waste is increasing. Chitosan has a dual function, which is osteoinductive because it contains growth factors that provide growth for osteoblast cells. Methods : A true experimental laboratory study with a post-test-only control group design was conducted on 30 Wistar rats and divided into two groups: the 0.2% chlorhexidine gluconate group and the chitosan group of scallop shells (Amusium Pleuronectes). The increase in the number of osteoblasts was compared and analyzed. Results : The results showed that the average in the control group on days 7, 14, and 21 was 1, 3.20, 8.80, while in the treatment group on days 7, 14, and 21, it was 12.2, 21.8, and 25. Based on the One Way Anova test results, a p-value of 0,000 (p <0.05) was obtained, meaning a significant difference in the average number of osteoblast cells in each study group. Conclusion : This study concludes that there is an increasing effect of alveolar bone osteoblasts from chitosan in scallop shell extract (Amusium Pleuronecte) in Wistar rats with periodontitis.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123798471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE METAL BRACKETS STAINLESS STEEL SURFACE ANALYSIS OF THE NICKEL (Ni) AND MANGAN (Mn) ION RELEASE","authors":"Grahita Aditya, Arlina Nurhapsari, Balqis Nureska Khomsiana","doi":"10.30659/medali.4.3.68-71","DOIUrl":"https://doi.org/10.30659/medali.4.3.68-71","url":null,"abstract":"","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126290733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-12-12DOI: 10.30659/medali.4.3.6-11
Andina Rizkia Putri Kusuma, Rahmawati Sri Praptiningsih, Arlina Nurhapsari
{"title":"COMPARISON OF THE NUMBER OF MACROPHAGES IN THE RAT REVERSIBLE PULPITIS AFTER APPLICATION OF BIODENTIN AND SIWAK EXTRACT","authors":"Andina Rizkia Putri Kusuma, Rahmawati Sri Praptiningsih, Arlina Nurhapsari","doi":"10.30659/medali.4.3.6-11","DOIUrl":"https://doi.org/10.30659/medali.4.3.6-11","url":null,"abstract":"Background: Oral disease still need special attention, especially in dentistry. Inflammation of the pulp is caused by the presence of irritants. One of the mechanical irritants is iatrogenic factors caused by operator error during preparation so that roof of pulp chamber is exposed. This condition is called reversible pulpitis/inflammation of the pulp. Cells that play a role during inflammation are macrophages which are the second defense cell after neutrophil apoptosis. A direct pulp capping procedure is indicated for this condition. The material commonly used is biodentin, but because the price tends to be expensive, alternative materials are needed. Siwak contains flavonoids which are known to play an important anti-inflammatory role in the healing of exposed pulp. The purpose of this study was to compare the number of macrophages in the dental pulp of rats with reversible pulpitis after administration of biodentin and siwak extract. Method: This research is a true experimental with a post test only group design, consisting of 2 treatment groups, namely the 75% siwak extract group and the biodentin group. The material is applied after the tooth has been prepared. The research sample used male wistar rats and sacrificed on the 3rd day. Samples were stained with Hematoxylin Eosin to see macrophage cells. Result: The data obtained were analyzed using the independent T-test. The test results showed a significant difference, with a value of p = 0.008 (p <0.05). Conclusion: The conclusion of this study that the siwak extract group showed a lower mean number of macrophage cells than the biodentin group.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126039687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-12-12DOI: 10.30659/medali.4.3.12-18
Rizki Amalina, I. Hutami
{"title":"QUALITATIVE ANALYSIS OF SANTRI HUSADA CADRES FORMATION AND ORAL DENTAL EXAMINATION AT ASSHODIQIYAH ISLAMIC BOARDING SCHOOL SEMARANG","authors":"Rizki Amalina, I. Hutami","doi":"10.30659/medali.4.3.12-18","DOIUrl":"https://doi.org/10.30659/medali.4.3.12-18","url":null,"abstract":"Background: Dental and oral health problems in Indonesia are still high due to the low number of health workers, both dentists and dental nurses. Therefore, the prevention and promotion of dental and oral health services must be improved formation of dental health cadres in a community. Islamic boarding schools are places of Islamic learning where students or santri live permanently and study together with teachers or Kiai. In a pesantren learning environment, it is essential to pay attention to health, especially the condition of the teeth and mouth, so as not to interfere with the learning process. This community service aims to form cadres and carry out dental and oral health checks by dentists and dental co-operative students, Faculty of Dentistry, Sultan Agung Islamic University (UNISSULA) Semarang. Method: In addition, this activity also aims to change students' behaviour thus they put more attention of the condition of their oral cavity and know the importance dental and oral care treatments according to their oral condition. With direct counselling provided by dentists, the cadres gain understanding and knowledge about the oral cavity, including the arrangement of teeth, various kinds of dental and oral problems, and how to treat them. In addition, the cadres also received training on how to brush their teeth with the right brush and toothpaste provided by the Co-assistant of dental students. Result: With the formation of 12 cadres, it is suggested that promotive, preventive, and referral activities for dental and oral health problems in the Asshodiqiyah Islamic boarding school can continue to run to reduce dental and oral health problems. Conclusion: Cadre activities for students and brushing teeth together can increase knowledge in the field of dental and oral health and the ability to clean the mouth teeth of PP students. Asshodiqiyah. This activity was also able to increase the awareness of the students to be more active in caring for and maintaining the health of their teeth and mouth.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115571489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-09-23DOI: 10.30659/medali.4.2.104-109
Ade Ismail Abdul Kodir, M. M. S. Abdurrohman, Talitha Novi Rahmaningrum
{"title":"THE EFFECT OF PERIODONTAL PACK WITH ADDITIONAL PLANTS OF IODINE (JATROPHA MULTIFIDA L.) POST CURRETAGE","authors":"Ade Ismail Abdul Kodir, M. M. S. Abdurrohman, Talitha Novi Rahmaningrum","doi":"10.30659/medali.4.2.104-109","DOIUrl":"https://doi.org/10.30659/medali.4.2.104-109","url":null,"abstract":"Background: Curettage is an act of scraping the granulation tissue on the lateral gingival wall of the periodontal pocket. After curettage, a periodontal pack was applied to control bleeding and keep the wound area clean. The addition of iodine leaves as an alternative because it contains flavonoids that can help the wound healing process. This study aims to determine the effect of adding 10% iodine leaf extract gel on the curettage process.Method: A true experimental laboratory study with a post-test only control group design on 20 wistar rats. The periodontal pack group and the periodontal pack group were added with 10% iodine leaf extract gel. Curettage healing was seen from the mean number of fibroblasts using One-Way Anova analysis.Result: The study showed the mean number of fibroblasts on the 5th and 7th day periodontal pack groups were 35.20 and 49.60, while those in the periodontal pack group with the addition of iodine leaf extract gel on 5th and 7th days were 45.80 and 50.80, respectively. The One-Way Anova test showed p > 0.05, there was a significant difference in the mean number of fibroblasts between the study groups.Conclusion: The conclusion is that there is an effect of giving 10% iodine leaf extract gel on the number of fibroblasts in the healing process of wistar rat curettage.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"172 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134387413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COMPARISON OF SHEAR STRENGTH CEMENTATION OF PREHEATED RESIN COMPOSITE AND RESIN CEMENT ON INDIRECT LITHIUM DISILICATE","authors":"Hafisza Syalsyabila Maghfira, Rahmat Hidayat, Rizki Amalina","doi":"10.30659/medali.4.2.110-118","DOIUrl":"https://doi.org/10.30659/medali.4.2.110-118","url":null,"abstract":"Background: The success of fixed dentures is influenced by the cementation procedure. Resin cement is the most commonly used luting materials. In addition to resin cement, there are other types of luting materials, preheated resin composite. Preheating resin composite allow the material to have a low level of viscosity, therefore can be used as luting material. The purpose of this study was to evaluate the comparison of the shear strength cementation of preheated resin composite and resin cement on indirect lithium disilicate. Method: This study is experimental laboratory with post test only control group design. The sample in this study are 12 pieces lithium disilicate with diameter 5.5 mm x 3 mm cemented divided into three groups based on types of luting materials (preheated resin composite microhybrid, preheated nanohybrid, and resin cement). After the cementation procedure, the samples were immersed in artificial saliva at 37ºC for 24 hours. The shear strength test was carried out with a universal testing machine. Data analysis with using One Way ANOVA. Result: The results of the average shear strength of each group were 11.98 MPa for preheated microhybrid, 11.41 MPa for preheated nanohybrid, and 14.22 MPa for resin cement. The results of the One Way ANOVA test showed that there was a significant differences between groups (p value 0.000). Conclusion: There was a significant difference in shear strength between preheated microhybrid, preheated nanohybrid, and resin cement. The highest shear strength was the resin cement group.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131818978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-09-23DOI: 10.30659/medali.4.2.152-156
Muhammad Jodie Setiawan, Rahmat Hidayat, Muhammad Dian Firdausy
{"title":"EFFECT OF FILLER NANO TITANIUM DIOXIDE (TiO2) PARTICLES ON FLEXURAL STRENGTH OF NYLON THERMOPLASTIC DENTURE BASE","authors":"Muhammad Jodie Setiawan, Rahmat Hidayat, Muhammad Dian Firdausy","doi":"10.30659/medali.4.2.152-156","DOIUrl":"https://doi.org/10.30659/medali.4.2.152-156","url":null,"abstract":"Background: Treatment of missing teeth can be done by using dentures. One of the denture base materials is thermoplastic nylon. The advantages of thermoplastic nylon are flexible and deformable. Various attempts have been made to maximize the quality of the denture, for example, by adding TiO 2 . TiO 2 can be used as a filler. Filler is the process of adding TiO 2 to the denture base. The advantages of TiO 2 particles are non-toxic, antimicrobial, and increasing the mechanical strength of denture bases.TiO 2 can reduce the porosity of the denture. Method: the design study is a post-test-only control with a total of 27 samples. A flexural test was performed using the UTM GD 1100. The statistical test used by the One Way Anova test. Result: The results showed that there was no significant effect on the flexural strength of thermoplastic nylon with the addition of 1% and 5% TiO 2 with the control group. The highest flexural strength was obtained in the treatment group of TiO 2 1 %, which was an average of 133.3867 N/mm 2 and the lowest flexural strength was obtained in the control group without the addition of TiO 2 , which was an average of 127.57378 N/mm 2 . The lowest flexural strength was found in the control group without the addition of TiO 2 , which was an average of 127.57378 N/mm 2 . Conclusion: There was no significant effects on the flexural strength of thermoplastic nylon with 1% and 5% TiO 2 added to the control group.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"63 11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116445145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jurnal MedaliPub Date : 2022-09-23DOI: 10.30659/medali.4.2.123-129
Sri Ainur Astutik, Benni Benyamin, R. Pratiwi
{"title":"THE DIFFERENCE IN COLOR CHANGE OF PREHEATED AND NON-PREHEATED NANOFILLER COMPOSITE RESIN AFTER IMMERSION IN NON-INSTANT AND INSTANT COFFEE","authors":"Sri Ainur Astutik, Benni Benyamin, R. Pratiwi","doi":"10.30659/medali.4.2.123-129","DOIUrl":"https://doi.org/10.30659/medali.4.2.123-129","url":null,"abstract":"Background : One of the aesthetic issues in using composite resin is the color change. This study aimed to compare the color changes of preheated and non-preheated nanofiller composite resin soaked in non-instant coffee and instant coffee. Method : This study involved 24 round composite resins with a diameter of 12 mm and a thickness of 2 mm. The samples were divided into two groups (n=12); group I was prepared at 68°C and group II was prepared at room temperature. After curing, the samples were immersed in distilled water at 37°C for 24 hours before being measured with a UV-vis spectrophotometer. Each group was divided into two sub-groups (n=6), one soaked in non-instant coffee and the other in instant coffee for three days, and the final color was measured. The data was analyzed using two independent t-tests with a significance level of α =0.05. Result : Two independent t-tests revealed a significant difference between preheated and non-preheated nanofiller composite resins soaked in non-instant coffee (p<0.05), as well as a significant difference between preheated and non-preheated nanofiller composite resins soaked in instant coffee (p<0.05). Conclusion: The preheating was effective to improve the color stability of composite resin after immersion in non-instant coffee and instant coffee.","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"20 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114102352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DENTAL HEALTH EDUCATION TO TEACHERS AND STUDENTS OF SD - IT AZZAHRA DEMAK IN THE ORDER OF IMPROVING KNOWLEDGE ABOUT MOUTH DENTAL HEALTH","authors":"Febia Astiawati Sugiarto, Erdianto Setya Wardhana, Nira Ardlina","doi":"10.30659/medali.4.2.136-141","DOIUrl":"https://doi.org/10.30659/medali.4.2.136-141","url":null,"abstract":"Background: Basic Health Research data from the Ministry of Health of the Republic of Indonesia 2018 (RISKESDAS 2018) shows that the proportion of oral cavity diseases in Indonesia is still high, reaching 57.6%. When viewed by age, the proportion is 67.3% from the age of 5-9 years, and 55.6% from the age of 10-14 years. This shows that the proportion of oral cavity diseases in school-age children is quite high. Counseling and training on dental and oral health is a learning process aimed at teachers or parents in order to increase the degree of dental and oral health in children to the maximum.Method: Counseling and training of elementary school teachers as dental health cadres, Implementation of interactive discussions to deepen understanding of dental health, Counseling on oral health to elementary school students Result: Dental Health Counseling activities at SD - IT Azzahra Demak were carried out for 2 days. Participants who attended this activity were 37 teachers and 190 elementary school students - IT Azzahra Demak Conclusion: Community service activities in the form of dental health counseling for teachers and students of SD - IT Azzahra Demak took place smoothly and had enormous benefits for increasing knowledge about dental health for elementary school teachers and elementary students. This will certainly improve the degree of dental health, especially for children","PeriodicalId":156596,"journal":{"name":"Jurnal Medali","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129487256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}