RGUHS Journal of Dental Sciences最新文献

{"title":"Ligaplants: The Next Generation Implants","authors":"","doi":"10.26715/rjds.14_1_2","DOIUrl":"https://doi.org/10.26715/rjds.14_1_2","url":null,"abstract":"The field of implant dentistry has turned out to be an imperative part of mainstream dentistry in the current epoch of dental practice. Osseointegrated implants are the most sought out implants currently. The main shortcomings of these implants is the lack of periodontal ligaments. To overcome this, a tissue engineering concept involving the formation of a periodontal ligament attachment around dental implants has now become a vital and beneficial tool to restore lost teeth. This regenerative approach for periodontal ligament, called the ligaplant is a therapeutic combination of the implant together with newly generated periodontal ligament cells. The periodontal ligament thus formed facilitates micro-movements and shock absorption that is antagonistic to conventional endosseous implants. The ligaplants thus generated have a positive impact on force distribution among the abutment teeth and prosthesis.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"356 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132862174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Erosive Potential of the Commonly Consumed Fruit-Based Beverages Among Children","authors":"U. Azher, Vijayashree C, Santhosh T Paul, Divya C Reddy","doi":"10.26715/rjds.13_4_7","DOIUrl":"https://doi.org/10.26715/rjds.13_4_7","url":null,"abstract":"Background: Dental erosion, an irreversible loss of dental hard tissue by a chemical process without the involvement of bacteria can be caused by various intrinsic and extrinsic factors. The consumption of foods with a low pH can cause a drop in the pH of the oral cavity below critical pH and its persistence can lead to a potential damage to teeth. As acidic beverages are likely to be a major factor in the etiology of dental erosion, it is important to determine the erosive potential of commonly consumed fruit-based beverages among children and educate the parents of their detrimental effects on teeth. Objectives: To evaluate and compare the pH and titratable acidity of the commonly consumed fruit-based beverages. Methodology: Three commonly consumed flavours (Orange, Apple, Mixed fruit) of fruit-based beverages (Group 1 - fresh fruit juice; Group 2 - packed fruit juice; Group 3 - packed fruit drink) were analyzed for pH and titratable acidity. The pH was determined using digital pH meter and the titratable acidity was measured by adding 1M sodium hydroxide (NaOH) in increments of 0.2 ml to 100 ml of the freshly prepared/ opened fruit-based beverages until the pH reached 5.5 and 7. The pH reading was measured after each increment (0.2 ml) of NaOH, until a stable pH was achieved. All the measurements were repeated in triplicates. Results: The pH of all drinks investigated in the present study ranged between 3.29 - 4.43. On comparison of the titratable acidity, packed fruit drink (Group 3) exhibited highest titratable acidity, followed by packed fruit juices (Group 2) and fresh fruit juices (Group 1). Conclusion: All the fruit-based beverages in the present study exhibited an acidic pH, which was well below the critical pH of 5.5, thereby exhibiting an erosive potential.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133006602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Quantification of “Cancer Stem Cells” in Potentially Malignant and Malignant Disorders of Head and Neck Region: A Flow-Cytometric Study","authors":"Vathsala Naik, M. Venkataswamy, Ruthu Nagraj, Ganga Gk, Gaurav","doi":"10.26715/rjds.13_3_7","DOIUrl":"https://doi.org/10.26715/rjds.13_3_7","url":null,"abstract":"Background: Cancer stem cells (CSCs) are subpopulation of cells existent in a cancerous mass of cells. These CSCs hijack the properties of stem cells like self-renewal as well as being resistant to any conventional cancer therapies. The objective of this study was to identify and quantify the presence of these CSCs by using surface markers CD44, CD133, and ALDH1 among three groups of subjects who were age and gender matched (Normal controls, Oral cancers, Potentially malignant disorders). Methodology: This study was conducted in a sample of 108 subjects who were divided into three groups: Group I- Controls (C), Group II- Oral cancer (OC), Group III- Potentially Malignant Disorders (PMDs). Among them, 40 subjects each were present in Group I & II and 28 subjects were included in group III, and they were respectively diagnosed histopathologically as OC and PMDs. The identification of the sub-population of CSCs by means of above mentioned surface markers was done using Flow cytometry. Results interpretation: Non-parametric tests were applied. Median age limit was 59 years in group II, which was higher than Group I or Group III subjects. p-value was 0.002* which was significant. Group I included 19 females (47.5%) and 21 males (52.5%). In Group II, 18 subjects were females (45%) and 22 were males (55%), and in Group III, 17 subjects were females (60.7%) and 11 were males (39.3%). p-value was 0.409, which was not very significant. In group II, 23 subjects (57.5%) were in clinical stage 2, 11 (27,5%) were in clinical stage 1 and six (15%) were in clinical stage 3. Histopathologically in group II, 15 (37.5%) were in grade I, 20 (50%) were in grade II and five (12.5%) were in grade III. Results of the three groups were compared and correlated regarding the presence of cancer stem cells based on the surface markers CD44, CD133 and ALDH1. Unlike other similar studies, our study showed no statistically significant presence of CD44, ALDH1 positive cells, but only CD133 was slightly significant. Inference: The results of our study showed no statistically significant evidence in identification of the presence of cancer stem cells in the oral cancers as well as potentially malignant disorders based on the presence of surface markers.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116660005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of antimicrobial properties of piperidine and apple cider vinegar on Streptococcus mutans and in-silico demonstration of the mechanism of action","authors":"R Shweta, B GeetaI, Aravind Ganessin","doi":"10.26715/rjds.13_1_7","DOIUrl":"https://doi.org/10.26715/rjds.13_1_7","url":null,"abstract":"In the seventeenth century, Antonie van Leeuwenhoek first observed “animalcules” swarming on living and dead matter out of curiosity he discovered these “animalcules” on his own teeth, it is reasonable to suggest that this early study of dental plaque was the first documented evidence of the existence of microbial biofilms. Biofilm is an association of micro-organisms in which microbial cells adhere to each other on a wide range surfaces i.e. biological and inert surfaces within a self-produced matrix of extracellular polymeric substances (EPS). Bacterial biofilm is infectious in nature and can result in infections. The microbial biofilm of caries is diverse and contains many facultative and obligate anaerobic bacteria, S. mutans, is the most common acid producer, primarily associated with caries. Due to increased resistance to antibiotics and other antimicrobial agents there is a need for effective and economical way to control the oral biofilm. Chlorhexidine is the most commonly used antimicrobial agent in dentistry as they destroy wide spectrum of microrganisms. Black pepper (Piper nigrum L.) is used in traditional medicinal systems as an antimicrobial due to presence of volatile compounds, tannins, phenols and various unknown substances. Similarly, acetic acid in apple cider vinegar effective against several types of bacteria and acts as an antimicrobial agent. Methodology: The current study focuses on In-vitro studies on biofilm establishment by S. mutans followed by competitive quenching of the biofilm by Piperidine from black pepper and apple cider vinegar which was carried out at 50,100 150µL concentrations using bacterial growth assessment by spectrophotometer and crystal violet assay. Chlorhexidine has been used as the positive control. Conclusion: Statistical analysis of the results was carried out to determine the correlation between the intensity of biofilm and the concentration of the test materials to evaluate the competence of the three candidate materials tested. The mechanism of anti-biofilm activity has been demonstrated through insilico docking between Piperidine and S. mutans. The study predicts the prospects of Piperidine based product formulations for dental treatments.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121959953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“The beginning of knowledge is the discovery of something we do not understand” -Frank Herbert","authors":"N. None","doi":"10.26715/rjds.13_1_1","DOIUrl":"https://doi.org/10.26715/rjds.13_1_1","url":null,"abstract":"<jats:p>None</jats:p>","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"33 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123615104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Efficacy of Acacia nilotica Against Microorganisms of Oral Cavity- An In Vitro Study","authors":"","doi":"10.26463/rjds.15_1_11","DOIUrl":"https://doi.org/10.26463/rjds.15_1_11","url":null,"abstract":"Background One of the frequent dental problems is the lack of self-rejuvenation capability of cartilage tissue. Acacia nilotica commonly known as babul thorny acacia Egyptian acacia or thorn mimosa has been proven in medicinal uses. The current study was carried out to evaluate the antimicrobial efficacy and phytochemical analysis of Acacia nilotica on microorganisms of oral cavity.Methods The flower extract of Acacia nilotica was prepared using Soxhlet apparatus. The antimicrobial testing S. mutans and L. acidophilus was done using agar well diffusion method. 0.2 chlorhexidine was used as a positive control. Minimum Inhibitory Concentration MIC was estimated using micro dilution assay and Minimum Bactericidal Concentration MBC was estimated using Colony Forming Unit CFU method. SPSS version 20 was used for statistical analysis.Results Phytochemical screening of flower extract of Acacia nilotica demonstrated the presence of alkaloids flavonoids glycosides tannins terpenoids steroids. The antimicrobial activity of the flower extract of Acacia nilotica showed varying degree of activity against the bacterial isolates. The flower extract showed relatively larger zones of inhibition 21 mm19 mm at 40 mgmL against S. mutans and L. acidophilus when compared with chlorhexidine. The MIC OD at 600 nm showed maximum inhibition at 40 mgmL against S. mutans and L. acidophilus which was about 78 and 91 respectively. The MBC value was the lowest concentration that showed no apparent growth on agar plate. Comparison between the groups against L. acidophilus was statistically significant than S. mutans.Conclusion The present study highlights the antimicrobial efficacy of Acacia nilotica extracts which could be considered in the preparation of indigenous herbal mouth rinse or toothpaste as the formulation inhibited all the micro-organisms tested in this study at low concentrations.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125472198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central odontogenic fibroma of maxilla: A case report","authors":"Megha S. Kulkarni, Sahana N S, C. J, R. S, Hajira Khatoon, R. Verghese","doi":"10.26463/rjds.14_4_1","DOIUrl":"https://doi.org/10.26463/rjds.14_4_1","url":null,"abstract":"Central odontogenic fibroma is a rare mesenchymal odontogenic neoplasm with a prevalence of 0.1 of all odontogenic tumors. Herein we present a case of a 63-year-old female with swelling in the left posterior maxillary region which was later diagnosed as a central type of odontogenic fibroma. A painless swelling was noted in the left maxillary tuberosity area. Orthopantamogram was advised which revealed a unilocular lesion with a mixed radiopaqueradiolucent appearance. This was associated with a spherically dense radiopaque mass in the left maxillary sinus region. A provisional diagnosis of the calcifying epithelial odontogenic tumor was made. An incisional biopsy was done and the specimen was sent for histopathological evaluation. The microscopic examination revealed inactive-looking odontogenic islands in the background of mature connective tissue stroma. Few foci of calcifications were also noted. After contemplating all the histological features a final diagnosis of central odontogenic fibroma was given. This case emphasizes the importance of histopathological examination of the unusual and rarely observed central odontogenic fibroma which can be missed due to similarities with other entities.nbsp","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124132947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of two different desensitizers on the shear bond strength of two newly introduced bonding agents following the total etch strategy: an in vitro study","authors":"A. Pandey, Shibani Shetty, B JayalakshmiK, PrasannalathaNadig, I. Sujatha, Deena Elizabeth","doi":"10.26715/rjds.12_1_5","DOIUrl":"https://doi.org/10.26715/rjds.12_1_5","url":null,"abstract":"Objective: Evaluate the shear bond strengths of two different dentin bonding agents following the pretreatment of dentine with two different desensitizing agents. Materials and methods: 60 premolar samples were grounded to expose the dentine. The teeth were categorized into three major groups. Each major group was subdivided into 2 subgroups of 10 samples each. Groups 1&2 involved no pretreatment with desensitizer prior to the bonding agents application. Groups 3&4 were pretreated with Gluma desensitizing agent prior to the use of All bond Universal as self-etching modality in group 3 and One Coat 7.0 in group 4. Groups 5&6 involved pretreatment with MS Coat One desensitizer and use of All bond Universal and One Coat7.0 bonding agents respectively. Shear bond testing of the samples were then evaluated by the universal testing machine. Analysis of the data was done using One-way ANOVA and pair-wise comparison was performed using Tukey’s multiple comparison test. Results: Control groups in which no pretreatment was done with any desensitizing agent had the highest bond strength when compared to the experimental groups. Among the desensitizers, significantly higher bond strength was shown by Gluma than MS Coat One. Conclusion: Gluma with One Coat 7.0 can be used to decrease the post-operative sensitivity without compromising bond strength.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"26 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129151989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To write is human, to edit is divine - Stephen king","authors":"D. A","doi":"10.26715/rjds.14_3_1","DOIUrl":"https://doi.org/10.26715/rjds.14_3_1","url":null,"abstract":"<jats:p>None</jats:p>","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"96 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129254872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D Bioprinting: The Imminent Future of Maxillofacial Rehabilitation","authors":"P. Kumar, N. Kalavathy, Mitha M Shetty, Archana K Sanketh, Rutuja Tidke","doi":"10.26715/rjds.13_3_11","DOIUrl":"https://doi.org/10.26715/rjds.13_3_11","url":null,"abstract":"Three dimensional (3D) printing is the most widely used technology in reconstructive surgery to fabricate complex maxillofacial prosthesis. 3D Bioprinting, a combination of 3D printing and tissue engineering is a rapidly expanding technology in the field of regenerative medicine for autograft production. It is an additive manufacturing process in which there is computer-aided deposition of living cells with extracellular matrix (ECM) components with a biomaterial in particular combinations, for the fabrication of 3D biologically active tissue. In this review, we introduced the techniques, principles, limitations and future prospects of 3D bioprinting, a method that can open up new avenues in reconstructive surgery, by solving the problem of organ shortage and decreasing the donor site morbidity.","PeriodicalId":155332,"journal":{"name":"RGUHS Journal of Dental Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126471057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}